Clinical trials: Choledocholithiasis
Choledocholithiasis With Cholecystitis With Obstruction, Obstructive Jaundice
Supraglottic Oxygenation Via Oral Transtracheal Catheter for Reducing the Incidence of Hypoxemia During ERCP Under Sedation
Endoscopic retrograde cholangiopancreatography (ERCP) is commonly used for the diagnosis and treatment of pancreatobiliary diseases.
- Conditions
- Choledocholithiasis With Cholecystitis With Obstruction, Obstructive Jaundice, Pancreatitis, Cholelithiasis
- Trial name
- NCT07637721
- Testing
- The Supraglottic Oxygenation Via Oral Transtracheal Catheter Group, The Regular Nasal Cannula
- Where
- 3 sites in China
- Volunteers
- 410 people
- Sponsor
- Zhejiang University
Cholelithiasis, Choledocholithiasis
Using da Vinci SP System for Patients With Cholelithiasis and Choledocholithiasis
A prospective, interventional, single arm study to investigate clinical feasibility of single-stage cholecystectomy and common bile duct exploration using da Vinci SP Surgical System (robotic surgery)
- Trial name
- NCT06852937
- Testing
- da Vinci SP Surgery System
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- National Taiwan University Hospital
Cholecystectomy, Laparoscopic, Choledocholithiasis
ChOlecystectomy aFter successFul Endoscopic Common Bile Duct Stone Extraction in Elderly
The goal of this study is to compare safety and efficacy of laparoscopic cholecystectomy versus wait-and-see policy after endoscopic removal of common bile duct stones in elderly.
- Conditions
- Cholecystectomy, Laparoscopic, Choledocholithiasis, Cholelithiasis
- Trial name
- COFFEE (NCT07001423)
- Testing
- Laparoscopic cholecystectomy
- Where
- 12 sites in Finland
- Volunteers
- 400 people
- Sponsor
- Helsinki University Central Hospital
Choledocholithiasis, Common Bile Duct Stones
Hyoscine Butylbromide During Transcystic Papillary Balloon Dilation for Choledocholithiasis
The purpose of the PAPRELAX study is to evaluate the intraoperative effect of intravenous hyoscine butylbromide during laparoscopic transcystic balloon dilation of the papilla of Vater in adult patients undergoing surgical…
- Trial name
- PAPRELAX (NCT07814976)
- Testing
- Hyoscine Butylbromide
- Where
- Latvia
- Volunteers
- 50 people
- Sponsor
- Riga East Clinical University Hospital
Cholecystectomy, Gallbladder
EUS-Guided Gallbladder Drainage Versus Conservative Management in Patients Unfit for Surgery After a Biliary Event Without Cholecystitis. DRECON Study
Cholecystectomy is considered the standard definitive treatment after an acute biliary event (biliary colic, acute pancreatitis, cholangitis, or choledocholithiasis).
- Conditions
- Cholecystectomy, Gallbladder, Endoscopic Ultrasound (EUS), Cholelithiasis
- Trial name
- DRECON (NCT07655778)
- Testing
- EUS-guided gallbladder drainage (EUS-GBD), Conservative management (CM)
- Volunteers
- 110 people
- Sponsor
- Hospital Mutua de Terrassa
Choledocholithiasis
Common Bile Duct Pressure After Surgical Exploration
A study that included patients of any gender between 15 and 70 years, with the diagnosis of choledocholithiasis who required a cholecystectomy with an exploration of bile ducts.
- Trial name
- NCT04968873
- Testing
- Cholecystectomy and common bile duct exploration
- Volunteers
- 13 people
- Sponsor
- Hospital General de Chihuahua - Dr. Salvador Zubirán Anchondo
Biliary Disease, Choledocholithiasis
Optimizing the Evaluation and Management of Patients With Suspected Choledocholithiasis
Choledocholithiasis (stone(s) in the common bile duct) is common. Untreated or missed, choledocholithiasis has high morbidity and mortality.
- Trial name
- NCT05141916
- Testing
- Endoscopic Retrograde Cholagiopancreatography (ERCP)
- Where
- Canada
- Volunteers
- 2,000 people
- Sponsor
- University of Calgary
Cholangitis Acute, Biliary Tract Diseases
Antimicrobial Resistance in Acute Cholangitis
This study prospectively explores antimicrobial resistance in patients with acute cholangitis undergoing ERCP procedures. By analyzing patient profiles, microbial cultures, and treatment outcomes, the current study seeks to…
- Conditions
- Cholangitis Acute, Biliary Tract Diseases, Jaundice; Malignant, Jaundice, Obstructive
- Trial name
- ARISE (NCT06197984)
- Testing
- ERCP
- Where
- Romania
- Volunteers
- 1,435 people
- Sponsor
- Emergency County Hospital Pius Brinzeu; Timisoara, Romania
Choledocholithiasis, Cholangiopancreatography, Endoscopic Retrograde
IDUS in CBD Stone Recurrence High Risk Patients
This study is designed to observed CBD stones cases with high recurrence risks applying IDUS or not during ERCP. Patients with CBD stone high recurrence risks were enrolled in this study, and prospectively randomized into IUDS…
- Conditions
- Choledocholithiasis, Cholangiopancreatography, Endoscopic Retrograde, Ultrasonography
- Trial name
- NCT06265311
- Testing
- IDUS examination
- Where
- China
- Volunteers
- 248 people
- Sponsor
- Shanghai Municipal Hospital of Traditional Chinese Medicine
Choledocholithiasis, Choledocholithiasis With Cholecystitis
The Significance of Laparoscopic Transcystic Papilla Vateri Balloon Dilatation in Patients With Choledocholithiasis.
A prospective randomized trial. It is planned to analyze groups of patients with cholecystitis and choledocholithiasis. As part of the study, after signing the consent, the patients will be divided into two groups that have…
- Trial name
- DILAILA (NCT07503964)
- Testing
- Endoscopic retrograde cholangiopancreatography with papillotomy and stone evacuation from common bile duct., Laparoscopic Cholecystectomy., Laparoscopic transcystic balloon dilatation of the papilla Vateri.
- Where
- Latvia
- Volunteers
- 100 people
- Sponsor
- Riga East Clinical University Hospital
Endoscopic Retrograde Cholangiopancreatography (ERCP), Choledocholithiasis
Role of Prophylactic Aggressive Hydration to Prevent Post-ERCP Pancreatitis
Endoscopic Retrograde Cholangiopancreatography, also called ERCP, is a procedure used to diagnose and treat disorders of the bile ducts and pancreas.
- Conditions
- Endoscopic Retrograde Cholangiopancreatography (ERCP), Choledocholithiasis, Bile Duct Disorder, Biliary Obstruction
- Trial name
- NCT07417020
- Testing
- Aggressive intravenous hydration with lactated Ringer's solution, Standard intravenous hydration with lactated Ringer's solution
- Where
- Pakistan
- Volunteers
- 126 people
- Sponsor
- Lahore General Hospital
Choledocholithiasis, Pancreatic Duct Stone
Comparing the Efficacy and Safety of Holmium Laser Lithotripsy Versus Electrohydraulic Lithotripsy for the Treatment of Difficult Choledocholithiasis and Pancreatic Duct Stones
The goal of this clinical trial is to learn if a low-power holmium laser works to treat large and/or difficult bile duct or pancreatic duct stones in adults. It will also learn about the safety of the low-wattage holmium laser.
- Trial name
- NCT07418112
- Testing
- Laser lithotripsy with low-wattage holmium laser, Electrohydraulic lithotripsy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Rush University Medical Center
Acute Cholangitis, Biliary Tract Infection
Comparative Efficacy Of Intraductal Antibiotic During ERCP In Acute Cholangitis
Does intraductal administration of antibiotics during endoscopic retrograde cholangiopancreatography (ERCP), in addition to standard systemic antibiotic therapy, improve clinical outcomes in patients with acute cholangitis…
- Conditions
- Acute Cholangitis, Biliary Tract Infection, Biliary Obstruction, Choledocholithiasis
- Trial name
- NCT07407491
- Testing
- Gentamicin - single dose, Distilled water
- Where
- Malaysia
- Volunteers
- 172 people
- Sponsor
- National University of Malaysia
Biliary Stones, Cholangiocarcinoma, Intrahepatic
Percutaneous Cholangiopancreatoscopy Registry
The Percutaneous Cholangiopancreatoscopy (PCPS) registry is an observational, multicentric, prospective, and retrospective registry of patients undergoing the percutaneous cholangiopancreatoscopy procedure at sites across the…
- Conditions
- Biliary Stones, Cholangiocarcinoma, Intrahepatic, Biliary Stricture, Cholelithiasis
- Trial name
- NCT05210322
- Testing
- Percutaneous cholangiopancreatoscopy
- Where
- United States
- Volunteers
- 679 people
- Sponsor
- Johns Hopkins University
Liver Circulation, Choledocholithiasis
Double Stent for Biliary Stones in Cirrhotic Patients
This prospective, single-center, interventional study enrolled 400 cirrhotic patients with large or complex common bile duct (CBD) stones that could not be removed during an initial Endoscopic Retrograde Cholangiopancreatography…
- Conditions
- Liver Circulation, Choledocholithiasis, Stent
- Trial name
- NCT07337291
- Testing
- Single 10 Fr Plastic Biliary Stent, Two 10 Fr Plastic Biliary Stent, Single 11.5 Fr Plastic Biliary Stent
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- National Liver Institute, Egypt
ERCP, Choledocholithiasis
Pre-cut Versus Intentional Double Guidewire for ERCP Cannulation: Prospective, Randomized Controlled Trial
Endoscopic retrograde cholangiopancreatography (ERCP) is an indispensable therapeutic procedure in the management of a wide spectrum of pancreaticobiliary disorders, including choledocholithiasis, benign and malignant biliary…
- Conditions
- ERCP, Choledocholithiasis, Biliary Drainage, Biliary Strictures Caused by Malignant Neoplasms
- Trial name
- PRIDE (NCT07329803)
- Testing
- Precut Sphincterotomy, Double Guidewire Technique
- Volunteers
- 840 people
- Sponsor
- Asian Institute of Gastroenterology, India
Choledocholithiasis
CBD Stenting vs Non-Stenting for Choledocholithiasis
The role of prophylactic biliary stenting after complete clearance of common bile duct stones in patients awaiting cholecystectomy remains controversial.
- Trial name
- NCT07331142
- Testing
- Temporary Plastic Biliary Stent Placement, Endoscopic Retrograde Cholangiopancreatography with Stone Clearance
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- National Liver Institute, Egypt
Choledocholithiasis, Papillary Stenosis
Endoscopic Antegrade Sphincterotomy (ASD) Versus Standard Sphincterotomy
This study compares endoscopic transpapillary antegrade sphincterotomy developed by Dr. Dovbenko (Antegrade Sphincterotomy Dovbenko, ASD) with conventional pull-type endoscopic sphincterotomy (EST) in patients undergoing…
- Conditions
- Choledocholithiasis, Papillary Stenosis, Biliary Obstruction, Gallstone Disease
- Trial name
- ASD (NCT04406961)
- Testing
- Endoscopic transpapillary antegrade sphincterotomy developed by Dr. Dovbenko., The antegrade sphincterotome developed by Dr. Dovbenko., Endoscopic sphincterotomy.
- Where
- Ukraine
- Volunteers
- 1,521 people
- Sponsor
- Military Medical Clinical Center of the Southern Region, Ukraine
Choledocholithiasis
Application of Machine Learning Models to Reduce Need for Diagnostic EUS or MRCP in Patients With Intermediate Likelihood of Choledocholithiasis
Machine learning predictive model can help in stratifying heterogenous intermediate likelihood group to reduce need for EUS or MRCP in selected subgroup of patients.
- Trial name
- NCT06066372
- Where
- India
- Volunteers
- 1,000 people
- Sponsor
- Asian Institute of Gastroenterology, India
Choledocholithiasis
Prospective Comparison of the Carbon Footprint of EUS vs MRCP for Evaluation of Suspected Choledocholithiasis
MRCP and EUS are diagnostically equivalent in detecting CBD stones among patients with intermediate risk, as shown in a landmark RCT.
- Trial name
- NCT07283185
- Where
- India
- Volunteers
- 200 people
- Sponsor
- Asian Institute of Gastroenterology, India