Clinical trials: Cholecystitis, active
Acute Cholecystitis
External Validation os the ACME Scoring System
Acute calculous cholecystitis (ACC) is the second most frequent surgical condition in emergency departments. The recommended treatment is surgical treatment (ST) and the accepted mortality is <1%, but in severe and/or fragile…
- Trial name
- ACME_2 (NCT06228027)
- Volunteers
- 10,000 people
- Sponsor
- Hospital del Mar
Acute Calculous Cholecystitis Candidate to Early Cholecystectomy
CHOLE-POSSUM PRO Validation for Prediction of Mortality After Cholecystectomy for Acute Calculous Cholecystitis: Protocol for a Prospective Multicenter Observational Study
CHOLE-POSSUM PRO is a prospective multicenter observational study on patients with ACC candidate to EC. The rationale of the study is to validate the CHOLE-POSSUM PRO SCORE for 30-day mortality in this population.
- Trial name
- NCT06908980
- Where
- Italy
- Volunteers
- 2,500 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Acute Cholecystitis
EUS-GBD vs Antibiotics for Patients at High Risk for Cholecystectomy
Objectives Acute cholecystitis commonly occurs in elderly patients who are at high-risk for surgery. Whether upfront Endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) is advantageous over antibiotics first for mild…
- Trial name
- NCT05893511
- Testing
- Endoscopic ultrasound-guided gallbladder drainage, Antibiotics first
- Where
- Hong Kong
- Volunteers
- 110 people
- Sponsor
- Chinese University of Hong Kong
Recurrent Cholecystitis, Cholecystitis
One vs. Two Stents for Gallbladder Disease
This randomized trial will look at whether placing two cystic duct stents is more effective than one cystic duct stent in preventing recurrent gallbladder disease (cholecystitis, gallstone pancreatitis, or biliary colic) among…
- Conditions
- Recurrent Cholecystitis, Cholecystitis, Symptomatic Gallbladder Disease, Biliary Colic
- Trial name
- NCT07222527
- Testing
- ERCP with one stent placement, ERCP with two stent placement
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Gallbladder Stone
A Strategy for Gallstone Expulsion Through Dietary Therapy
This study is a double-blind, prospective, single-center controlled trial conducted at a tertiary hospital, aiming to determine whether dietary therapy can effectively expel gallstones.
- Trial name
- NCT06699030
- Testing
- Functional fatty acids
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
Cholecystitis, Acute, Cholecystectomy, Laparoscopic
Implementation of RICA (ERAS) Guidelines in Grade II Acute Cholecystitis Undergoing Early Laparoscopic Cholecystectomy
Background Acute cholecystitis (sudden gallbladder inflammation, usually due to gallstones) is a highly frequent surgical emergency.
- Conditions
- Cholecystitis, Acute, Cholecystectomy, Laparoscopic, Enhanced Recovery After Surgery
- Trial name
- COLERICA II (NCT07695922)
- Testing
- RICA Perioperative Care Pathway
- Where
- Spain
- Volunteers
- 146 people
- Sponsor
- Hospital d'Igualada
Avascular Necrosis of the Femoral Head, Coronary Artery Disease (CAD)
Desflurane Potentially Induces Postoperative Cognitive Dysfunction in Elderly Patients Undergoing Perioperative Procedures by Modulating Cdc42 and Clock Proteins
This clinical trial investigates whether desflurane induces postoperative cognitive dysfunction (POCD) in elderly patients undergoing perioperative procedures by modulating Cdc42 and Clock proteins.
- Conditions
- Avascular Necrosis of the Femoral Head, Coronary Artery Disease (CAD), Benign Prostatic Hyperplasia (BPH), Cholecystitis
- Trial name
- NCT06772558
- Testing
- Desflurane Inhalation, mechanical ventilation (MV)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xiaguang Duan
Acute Appendicitis, Acute Cholecystitis
Web-based International Register of Emergency Surgery and Trauma
The WIRES-T project (Web-based International Registry of Emergency General Surgery and Trauma) has been set up to allow to all the EGS (Emergency General Surgery) and Trauma surgeons to register their activity and to obtain a…
- Conditions
- Acute Appendicitis, Acute Cholecystitis, Acute Diverticulitis, Post-operative Complications
- Trial name
- WIRES-T (NCT03643718)
- Testing
- Emergency General Surgery
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Cholecystitis, Acute
Bile Aspiration vs Drain in Acute Cholecystitis
In order to compare percutaneous cholecystostomy and leaving a drain in situ with percutaneous gallbladder aspiration we plan to undertake a double-blind randomized controlled trial.
- Trial name
- NCT03012243
- Testing
- Gallbladder aspiration, Cholecystostomy
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Acute Cholecystitis
Diagnostic Value of Deep Learning-Based Rapid MRI in Preoperative Evaluation of Acute Cholecystitis
This is a single-center, prospective observational study at Peking Union Medical College Hospital. The main goal is to evaluate the image quality and clinical value of a new fast abdominopelvic MRI sequence that uses deep…
- Trial name
- NCT07551375
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking Union Medical College Hospital
Acute Cholecystitis
Conservative Versus Proactive Management of Acute Cholecystitis After EUS-guided Transmural Gallbladder Drainage: FUGITIVE Trial (FUGITIVE)
Patients with gallbladder inflammation (acute cholecystitis) who cannot undergo surgery due to their fragility and surgical risk require a gallbladder drainage.
- Trial name
- FUGITIVE (NCT06967597)
- Testing
- Cholecystoscopy and gallbladder cleaning
- Where
- 2 sites in Spain
- Volunteers
- 82 people
- Sponsor
- Hospital General Universitario de Alicante
Common Bile Duct Calculi, Acute; Cholecystitis, Choledocholithiasis
Modified Laparoscopic Transcystic Biliary Drainage in the Management of Cholecystocholedocholithiasis
The modified laparoscopic transcystic biliary drainage which we developed in the treatment of cholecystocholedocholithiasis has some advantages over conventional techniques.
- Conditions
- Common Bile Duct Calculi, Acute; Cholecystitis, Choledocholithiasis, Acute Cholecystitis With Obstruction, Acute Cholangitis
- Trial name
- NCT06011941
- Testing
- Modified laparoscopic transcystic biliary drainage
- Where
- China
- Volunteers
- 310 people
- Sponsor
- Peking University Third Hospital
Gallstone, Gallstone; Cholecystitis, Acute
Indocyanine Green Fluorescence During Fundus First Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is the routine method for managing gallstone disease. This is considered a safe procedure with low risk of severe complications.
- Trial name
- INFUNDUS (NCT06918210)
- Testing
- Indocyanine Green, Cholangiography
- Volunteers
- 294 people
- Sponsor
- Karolinska Institutet
Cholecystitis, Acute
Percutaneous Drainage Versus EUS-guided Gallbladder Drainage in Poor Surgical Patients With Cholecystitis
The goal of this clinical trial is to learn if endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) works better than percutaneous gallbladder drainage (PT-GBD) for people with acute cholecystitis (inflammation of the…
- Trial name
- EUSCAPE (NCT07792486)
- Testing
- Endoscopic ultrasound guided gallbladder drainage (EUS-GBD) with lumen apposing metal stents (LAMS), Percutaneous gallbladder drainage
- Where
- Netherlands
- Volunteers
- 212 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Hemodynamics Instability, Post Operative Pain
Evaluating Perioperative Outcomes: Dexmedetomidine vs Lignocaine in Laparoscopic Chlolecystectomy
Nowadays laparoscopic surgery is the first choice for many surgeries. Such surgeries have revolutionized the surgical practice and has markedly reduced the incidence of intraoperative and postoperative complications.
- Conditions
- Hemodynamics Instability, Post Operative Pain, Gastrointestinal Dysfunction, Cholecystitis
- Trial name
- NCT06740903
- Testing
- inj. dexmedetomidine infusion @ 0.2-0.4 μg/kg/h, inj. lignocaine infusion @1-2 mg/kg/h
- Where
- Pakistan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Sahiwal medical college sahiwal
Choledocholithiasis With Cholecystitis With Obstruction, Obstructive Jaundice
Feasibility and Safety of Supraglottic Oxygen Delivery Via an Endotracheal Tube for Non-intubated ERCP Anesthesia: A Two-Stage Phase II Clinical Study
Endoscopic retrograde cholangiopancreatography (ERCP) is a technique for evaluating the bile duct, pancreatic duct, and ampulla.
- Conditions
- Choledocholithiasis With Cholecystitis With Obstruction, Obstructive Jaundice, Pancreatitis, Cholelithiasis
- Trial name
- NCT07051980
- Testing
- Supraglottic Oxygen Delivery via an Endotracheal Tube
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Zhejiang University
Cholecystitis, Liver Neoplasms
Feasibility Study of Non-Contact Imaging-Based Physiological Monitoring in the Operating Room
This study aims to evaluate the feasibility and accuracy of a non-contact, camera-based physiological monitoring technology in a perioperative setting (including anesthesia induction, surgery, and recovery).Conventional vital…
- Conditions
- Cholecystitis, Liver Neoplasms, Cholelithiasis, Inguinal Hernia
- Trial name
- IBPM (NCT07473687)
- Testing
- Non-contact rPPG software
- Where
- Taiwan
- Volunteers
- 315 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Gastric Outlet Obstruction, Biliary Obstruction
Prospective Registry Of Therapeutic EndoscopiC ulTrasound
This registry aims to analyze long-term outcomes of therapeutic EUS (T-EUS) procedures, as well as to describe clinical and technical variables potentially predicting clinical success or adverse events, for a better selection of…
- Conditions
- Gastric Outlet Obstruction, Biliary Obstruction, Acute Pancreatic Fluid Collection, Acute Pancreatitis With Infected Necrosis
- Trial name
- PROTECT (NCT04813055)
- Testing
- Therapeutic EUS, Percutaneous Procedures, Surgical Interventions
- Where
- Italy
- Volunteers
- 510 people
- Sponsor
- Paolo Giorgio Arcidiacono, MD
Cholecystitis, Acute
SnapChole: An International, Time-Bound Prospective Platform Study of Management Strategies and Outcomes in Acute Calculous Cholecystitis
This study aims to understand how different treatment approaches for acute gallbladder inflammation (acute calculous cholecystitis) affect patient outcomes in real-world hospital settings.
- Trial name
- SnapChole (NCT07568080)
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- European Society for Trauma and Emergency Surgery
Cholecystitis; Gallstone, Cholecystolithiasis
A (5-5-5-8) Technique for Laparoscopic Cholecystectomy
The aim of this current study is to investigate the effectiveness and safety of a novel technique which is the 5-5-5-8 where the camera port is 5 mm.
- Conditions
- Cholecystitis; Gallstone, Cholecystolithiasis, Cholecystitis, Chronic
- Trial name
- NCT06045546
- Testing
- 5-5-5-8 technique, 10-10-5-5 technique
- Where
- Egypt
- Volunteers
- 524 people
- Sponsor
- ClinAmygate