Clinical trials: Cholecystectomy, open to volunteers
Abdominal Disorder
Evaluation of Laparoscopic Cholecystectomy and Concomitant Paraumbilical Hernia Repair
Umbilical hernia frequently accompanies cholelithiasis. It is possible to repair these hernias after completing cholecystectomy.
- Trial name
- NCT06317779
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
External Oblique Intercostal Plane Block, Subcostal Transverse Abdominis Plane Block
Comparison of the Effects of External Oblique Intercostal Plane Block, Subcostal Transverse Abdominis Plane Block, and Their Combination in the Management of Postoperative Pain in Laparoscopic Cholecystectomy Surgery
This study aims to compare the efficacy of Subcostal Transversus Abdominis Plan Block, External Oblique Intercostal Plan Block and the combination of these two blocks, which are used in anesthesiology practice for postoperative…
- Trial name
- NCT07179731
- Testing
- subcostal transversus abdominis plane block, External Oblique Intercostal Plane Block, external oblique intercostal plane block and subcostal transversus abdominis plane block combination
- Volunteers
- 105 people
- Sponsor
- Istanbul Medeniyet University
Acute Cholecystitis
External Validation os the ACME Scoring System
Acute calculous cholecystitis (ACC) is the second most frequent surgical condition in emergency departments. The recommended treatment is surgical treatment (ST) and the accepted mortality is <1%, but in severe and/or fragile…
- Trial name
- ACME_2 (NCT06228027)
- Volunteers
- 10,000 people
- Sponsor
- Hospital del Mar
Airway Edema, Postoperative Complications
Effect of Prophylactic Dexamethasone vs Placebo on Airway Dimensions Assessed by Ultrasonography in Patients Undergoing Laparoscopic Cholecystectomy
During laparoscopic surgery, the abdomen is inflated with carbon dioxide gas (pneumoperitoneum), which alters venous return and fluid distribution, potentially leading to swelling in the tissues of the upper airway.
- Conditions
- Airway Edema, Postoperative Complications, Cholecystolithiasis
- Trial name
- NCT07918495
- Testing
- Dexamethasone
- Volunteers
- 80 people
- Sponsor
- Assiut University
Cholelithiasis, Postoperative Pain
Pain Diary Use After Laparoscopic Cholecystectomy
This randomized controlled study aims to evaluate the effectiveness of using a pain diary in the assessment of early postoperative pain in patients undergoing laparoscopic cholecystectomy.
- Trial name
- PDP-LC (NCT07308730)
- Testing
- Postoperative Pain Management Protocol for Laparoscopic Cholecystectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people
- Sponsor
- Muğla Sıtkı Koçman University
Cholelithiasis
Electrosurgical Patterns and Learning Curve in Elective Laparoscopic Cholecystectomy
This prospective observational study will examine how electrosurgical activation patterns during elective laparoscopic cholecystectomy are associated with surgeon experience and intraoperative difficulty.
- Trial name
- ELECTRO-LC (NCT07888491)
- Testing
- Elective laparoscopic cholecystectomy
- Where
- Croatia
- Volunteers
- 165 people
- Sponsor
- University Hospital of Split
Postoperative Pain
Comparison of Intraperitoneal Bupivacaine and Saline Irrigation for Pain Relief After Laparoscopic Cholecystectomy
This randomized clinical trial compared intraperitoneal irrigation of bupivacaine(a local anesthetic) vs a control group receiving normal saline for relief of post operative pain following laparoscopic gallbladder surgery.
- Trial name
- NCT07650760
- Testing
- Bupivacain, Saline (0.9% NaCl)
- Where
- Pakistan
- Volunteers
- 106 people
- Sponsor
- Wah Medical college , POF hospital
Laparoscopic Cholecystectomy, Postoperative Pain
Subcostal TAP Block and EEG Dynamics in Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is a commonly performed minimally invasive surgical procedure. Despite its minimally invasive nature, surgical stimulation and pneumoperitoneum may cause pain-related physiological and…
- Conditions
- Laparoscopic Cholecystectomy, Postoperative Pain, Intraoperative Nociception
- Trial name
- NCT07818954
- Testing
- Remifentanil, Ultrasound-Guided Subcostal Transversus Abdominis Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Cholecystectomy, Laparoscopic
Smart Intraoperative Reminder to Implement Safety Principles in Laparoscopic Cholecystectomy
The Critical View of Safety (CVS) is universally recommended to prevent bile duct injuries in laparoscopic cholecystectomy. However, CVS is underutilized and bile duct injuries are not decreasing.
- Trial name
- CVS-Notifier (NCT06895200)
- Testing
- CVS-Notifier SaMD
- Where
- France
- Volunteers
- 40 people
- Sponsor
- IHU Strasbourg
Laparoscopic Cholecystectomy
Unilateral Right-Sided Erector Spinae Plane Block for Analgesia in Laparoscopic Cholecystectomy: Does the Volume Matter? A Randomized Controlled Trial
Laparoscopic cholecystectomy is one of the most common surgeries today, cause it has many advantages over open cholecystectomy. (1) Although these advantages pain remains a big problem after laparoscopic cholecystectomy which…
- Trial name
- NCT07027540
- Testing
- Bupivacaine 0.25% 20ml, 2mg of dexamethasone, 35 ml of Bupivacaine 0.25%
- Volunteers
- 60 people
- Sponsor
- Assiut University
Acute Calculous Cholecystitis Candidate to Early Cholecystectomy
CHOLE-POSSUM PRO Validation for Prediction of Mortality After Cholecystectomy for Acute Calculous Cholecystitis: Protocol for a Prospective Multicenter Observational Study
CHOLE-POSSUM PRO is a prospective multicenter observational study on patients with ACC candidate to EC. The rationale of the study is to validate the CHOLE-POSSUM PRO SCORE for 30-day mortality in this population.
- Trial name
- NCT06908980
- Where
- Italy
- Volunteers
- 2,500 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Acute Cholecystitis
EUS-GBD vs Antibiotics for Patients at High Risk for Cholecystectomy
Objectives Acute cholecystitis commonly occurs in elderly patients who are at high-risk for surgery. Whether upfront Endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) is advantageous over antibiotics first for mild…
- Trial name
- NCT05893511
- Testing
- Endoscopic ultrasound-guided gallbladder drainage, Antibiotics first
- Where
- Hong Kong
- Volunteers
- 110 people
- Sponsor
- Chinese University of Hong Kong
Laparoscopic Cholecystectomy, Postoperative Pain
Subcostal TAP Block Versus Combined Subcostal TAP and Recto-Intercostal Fascial Plane Block for Analgesia After Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is commonly associated with moderate postoperative pain, particularly during the early postoperative period.
- Trial name
- NCT07869316
- Testing
- Subcostal Transversus Abdominis Plane Block, Recto-Intercostal Fascial Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Recurrent Cholecystitis, Cholecystitis
One vs. Two Stents for Gallbladder Disease
This randomized trial will look at whether placing two cystic duct stents is more effective than one cystic duct stent in preventing recurrent gallbladder disease (cholecystitis, gallstone pancreatitis, or biliary colic) among…
- Conditions
- Recurrent Cholecystitis, Cholecystitis, Symptomatic Gallbladder Disease, Biliary Colic
- Trial name
- NCT07222527
- Testing
- ERCP with one stent placement, ERCP with two stent placement
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Postoperative Bowel Function, Postoperative Pain
Fentanyl vs. Remifentanil in Laparoscopic Cholecystectomy: Effects on Bowel Function and Pain
Background: Postoperative ileus (POI) is a common complication after abdominal surgery, leading to delayed gastrointestinal recovery, prolonged hospitalization, and increased healthcare costs.
- Trial name
- NCT07182097
- Testing
- Fentanyl 2 µg/kg IV bolus + 1-2 µg/kg/h infusion during anesthesia, Remifentanil 1 µg/kg IV bolus + 0.1-1 µg/kg/min infusion during anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Konya City Hospital
Laparoscopic Surgery, Laparoscopic Appendectomy
Pre-incisional Infiltration With Ropivacaine Plus Diprospan for Relieving Postoperative Pain After Laparoscopic Surgery
Incisional infiltration is the simplest, safest, and most effective anesthesia method for preventing incision pain after laparoscopic surgery, but even using long-acting local anesthetics, the effectiveness of postoperative…
- Conditions
- Laparoscopic Surgery, Laparoscopic Appendectomy, Laparoscopic Cholecystectomy, Laparoscopic Hernia Repair Surgery
- Trial name
- NCT07626463
- Testing
- Pre-incisional infiltration with ropivacaine and diprospan, Pre-incisional infiltration with ropivacaine alone
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Beijing Tiantan Hospital
Analgesia After Laparoscopic Cholecystectomy
Opioid-Free Analgesia for Laparoscopic Cholecystectomy
laparoscopic cholecystectomy (LC) is often accompanied by moderate-to-severe postoperative pain. opioid-free anesthesia (OFA) consists of a variety of non-opioid narcotic drugs and techniques.
- Trial name
- NCT07750769
- Testing
- EOI with OFA, OFA
- Volunteers
- 70 people
- Sponsor
- Assiut University
Analgesia, Pain Management
Ultrasound-Guided Recto-Intercostal Fascial Plane Block in Laparoscopic Cholecystectomy
The aim of the study is to reduce postoperative pain by performing rectointercostal block in L/S cholecystectomy surgeries. Main goal is to provide well managed post-operative analgesia.
- Conditions
- Analgesia, Pain Management, Pain, Acute Post-Operative
- Trial name
- NCT07745972
- Testing
- Rectointercostal facial plane block using bupivacaine 0.25%
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istinye University
Common Bile Duct Stones
Endoscopic Retrograde Cholangiopancreatography Access and Complication Rates After Cholecystectomy With Common Bile Duct Stones
The aim of this retrospective, register-based study is to investigate whether access, or no access, to endoscopic retrograde cholangiopancreatography (ERCP) at a surgical unit is associated with the risk of complications in…
- Trial name
- NCT07640204
- Testing
- Exposed group
- Volunteers
- 10,000 people
- Sponsor
- Karolinska Institutet
Breast Lumpectomy, Laparoscopic Cholecystectomy
De-Implementation of Low-value Testing in Patients Undergoing Low-Risk Surgery
This trial aims to evaluate the effectiveness of a multi-level, multi-component de-implementation strategy to reduce unnecessary preoperative testing.
- Conditions
- Breast Lumpectomy, Laparoscopic Cholecystectomy, Inguinal Hernia Repair
- Trial name
- NCT06934564
- Testing
- Active de-Implementation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Michigan