External Oblique Intercostal Plane BlockNCT07179731
Comparison of the Effects of External Oblique Intercostal Plane Block, Subcostal Transverse Abdominis Plane Block, and Their Combination in the Management of Postoperative Pain in Laparoscopic Cholecystectomy Surgery
A study testing subcostal transversus abdominis plane block, External Oblique Intercostal Plane Block and external oblique intercostal plane block and subcostal transversus abdominis plane block combination in people with External Oblique Intercostal Plane Block and Subcostal Transverse Abdominis Plane Block, run by Istanbul Medeniyet University.
Trial summary
This study aims to compare the efficacy of Subcostal Transversus Abdominis Plan Block, External Oblique Intercostal Plan Block and the combination of these two blocks, which are used in anesthesiology practice for postoperative pain in laparoscopy cholecystectomy surgery. Read more about this study
- Who is it for?
- Ages 18 to 80 years
- Conditions the study is for
- External Oblique Intercostal Plane Block, Subcostal Transverse Abdominis Plane Block
- What is being tested?
- subcostal transversus abdominis plane block, External Oblique Intercostal Plane Block and external oblique intercostal plane block and subcostal transversus abdominis plane block combination
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 105 participants
- Where
- No sites listed yet
- Study dates
- 23 Sep 2025to 31 Dec 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 80 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Patients scheduled for laparoscopic cholecystectomy surgery
- Patients aged between 18 to 80 years
- Having an anesthesiology risk assessment of ASA I, II, or III
Who cannot join
- Patients who do not give written and oral consent
- Patients with coagulopathy
- History of allergic reaction or intoxication by local anesthetics
- Severe organ failure
- Mental retardation or illiteracy
- Presence of infection on the injection site
- Pregnancy
- Patients whom the procedure is extended to open cholecystectomy
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
This study aims to compare the efficacy of Subcostal Transversus Abdominis Plan Block, External Oblique Intercostal Plan Block and the combination of these two blocks, which are used in anesthesiology practice for postoperative pain in laparoscopy cholecystectomy surgery.
- Being tested
- subcostal transversus abdominis plane block, External Oblique Intercostal Plane Block, external oblique intercostal plane block and subcostal transversus abdominis plane block combination
- Keywords
- external oblique intercostal block, subcostal transverse abdominis block
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
subcostal transversus abdominis plane blockProcedure or surgery
Under ultrasound guidance, 30 ml of bupivacaine is injected along the fascia of transversus abdominis muscle.
External Oblique Intercostal Plane BlockProcedure or surgery
Under ultrasound guidance, 30 ml of bupivacaine is injected between the fascias of external oblique and intercostal muscles.
external oblique intercostal plane block and subcostal transversus abdominis plane block combinationProcedure or surgery
The combination of the two blocks will be applied in 15 ml of volume for each.
| Study group | Role | What they receive |
|---|---|---|
| Group 1: subcostal transversus abdominis plane block | Active comparator | This group will receive 30 ml 0.25% of bupivacaine for the subcostal transversus abdominis plane block prior to surgery. Receives: Procedure: subcostal transversus abdominis plane block |
| Group 2: external oblique intercostal plane block | Active comparator | This group will receive 30 ml 0.25% of bupivacaine for the external oblique intercostal plane block prior to surgery. Receives: Procedure: External Oblique Intercostal Plane Block |
| Group 3: subcostal transversus abdominis and external oblique intercostal plane block combination | Active comparator | This group will receive 15 ml 0.25% of bupivacaine for the external oblique intercostal plane block, in combination with 15 ml 0.25% of bupivacaine for the subcostal transversus abdominis plane block prior to surgery. Receives: Procedure: external oblique intercostal plane block and subcostal transversus abdominis plane block combination |
What is being measured
The primary outcome is the main question the study is designed to answer.
Postoperative Analgesic Consumption
The opioid consumption via patient controlled analgesia (PCA) in 24 hours postoperatively
Measured: 24 hours postoperatively
Secondary outcomes (1)
Postoperative Pain Scores
Postoperative pain will be assessed using Numeric Rating Scale (NRS) at 30 mins, and 1, 4, 8, 12, 24 hours after surgery.
Measured: up to 24 hours after surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 Sep 2025
- Study start23 Sep 2025 (estimated)
- Primary completion10 Dec 2025 (estimated)
- Study completion31 Dec 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for External Oblique Intercostal Plane BlockStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 105 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Istanbul Medeniyet University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Faruk Komez, Istanbul Medeniyet University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07179731
- Sponsor's protocol ID
- EOİKB001
- Status last verified
- Jul 2025
- First submitted
- 31 Jul 2025
- Last updated
- 18 Sep 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 18 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of the Effects of External Oblique Intercostal Plane Block, Subcostal Transverse Abdominis Plane Block, and Their Combination in the Management of Postoperative Pain in Laparoscopic Cholecystectomy Surgery
- ClinicalTrials.gov ID
- NCT07179731
- Acronym / sponsor ID
- EOİKB001
- Keywords
- external oblique intercostal block, subcostal transverse abdominis block
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 105 participants (estimated)
- Lead sponsor
- Istanbul Medeniyet UniversityUniversity, hospital or other
- Study start
- 23 Sep 2025 (estimated)
- Primary completion
- 10 Dec 2025 (estimated)
- Study completion
- 31 Dec 2025 (estimated)
- First posted
- 18 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to compare the efficacy of Subcostal Transversus Abdominis Plan Block, External Oblique Intercostal Plan Block and the combination of these two blocks, which are used in anesthesiology practice for postoperative pain in laparoscopy cholecystectomy surgery.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Group 1: subcostal transversus abdominis plane block | Active comparator | Procedure: subcostal transversus abdominis plane blockThis group will receive 30 ml 0.25% of bupivacaine for the subcostal transversus abdominis plane block prior to surgery. |
| Group 2: external oblique intercostal plane block | Active comparator | Procedure: External Oblique Intercostal Plane BlockThis group will receive 30 ml 0.25% of bupivacaine for the external oblique intercostal plane block prior to surgery. |
| Group 3: subcostal transversus abdominis and external oblique intercostal plane block combination | Active comparator | Procedure: external oblique intercostal plane block and subcostal transversus abdominis plane block combinationThis group will receive 15 ml 0.25% of bupivacaine for the external oblique intercostal plane block, in combination with 15 ml 0.25% of bupivacaine for the subcostal transversus abdominis plane block prior to surgery. |
Who may qualify
- Ages
- 18 to 80 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Patients scheduled for laparoscopic cholecystectomy surgery
- Patients aged between 18 to 80 years
- Having an anesthesiology risk assessment of ASA I, II, or III
Key exclusion criteria (8 listed)
- Patients who do not give written and oral consent
- Patients with coagulopathy
- History of allergic reaction or intoxication by local anesthetics
- Severe organ failure
- Mental retardation or illiteracy
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| subcostal transversus abdominis plane blockUnder ultrasound guidance, 30 ml of bupivacaine is injected along the fascia of transversus abdominis muscle. | Procedure or surgery | Group 1: subcostal transversus abdominis plane block |
| External Oblique Intercostal Plane BlockUnder ultrasound guidance, 30 ml of bupivacaine is injected between the fascias of external oblique and intercostal muscles. | Procedure or surgery | Group 2: external oblique intercostal plane block |
| external oblique intercostal plane block and subcostal transversus abdominis plane block combinationThe combination of the two blocks will be applied in 15 ml of volume for each. | Procedure or surgery | Group 3: subcostal transversus abdominis and external oblique intercostal plane block combination |
Primary outcome
Postoperative Analgesic Consumption
Time frame: 24 hours postoperatively
The opioid consumption via patient controlled analgesia (PCA) in 24 hours postoperatively
1 secondary outcome
Postoperative Pain Scores
Time frame: up to 24 hours after surgery
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Sep 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing subcostal transversus abdominis plane block, External Oblique Intercostal Plane Block and external oblique intercostal plane block and subcostal transversus abdominis plane block combination in people with External Oblique Intercostal Plane Block and Subcostal Transverse Abdominis Plane Block, run by Istanbul Medeniyet University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 18 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Faruk Kömez (+90 507 688 28 50, dr.farukkomez@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Postoperative Analgesic Consumption (time frame: 24 hours postoperatively). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Sep 2025.