Clinical trials: Chlorhexidine Gel
Dental Caries, Infection, Bacterial
Evaluation of Gel and Solution of Chlorhexidine in Disinfection Root Canals of Primary Anterior Teeth.
The process of removing bacteria and their products from the root canals is an essential step that is achieved through the combination of mechanical preparation and irrigation with chemicals.
- Conditions
- Dental Caries, Infection, Bacterial, Tooth, Deciduous
- Trial name
- NCT05361278
- Testing
- Chlorhexidine solution, Activated chlorhexidine solution, Chlorhexidine gel
- Where
- Syria
- Volunteers
- 15 people
- Sponsor
- Damascus University
Diabetes Mellitus, Type 2, Periodontitis, Adult
Evaluation of Chlorhexidine Gel Associated with Photodynamic Therapy in the Treatment of Chronic Periodontitis in Type 2 Diabetics
The objective of this clinical trial is to evaluate chlorhexidine gel associated with photodynamic therapy in the treatment of chronic periodontitis in Type 2 diabetics The main questions it aims to answer are: To evaluate if the…
- Conditions
- Diabetes Mellitus, Type 2, Periodontitis, Adult, Periodontitis
- Trial name
- NCT06469294
- Testing
- Control (C) - Saline Gel, Test (t) - Photodynamic therapy and 2% chlorexidine and 0,005% methylene blue
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Catheter-Related Infections
Chlorhexidine-Impregnated Sponge Dressing: A Clinical Trial
The purpose of this study is to compare the use of chlorhexidine-gel-impregnated dressing and the transparent polyurethane film dressing as coverage of the site of insertion of central venous catheter, in the evaluation of…
- Trial name
- CISDCT (NCT02472158)
- Testing
- chlorhexidine-gel-impregnated dressing, Polyurethane film dressing
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- University of Sao Paulo
Peri-implant Mucositis
Domiciliary Use of Hyaluronic Acid Gel Solutions vs Domiciliary Use of Chlorhexidine Mouthwash 0,20% for the Management of Peri-implant Mucositis Sites
This is a randomized controlled clinical trial (RCT). After signing the informed consent, patients satisfying the inclusion criteria will undergo supragingival and subgingival professional oral hygiene of both arches performed…
- Trial name
- NCT05312593
- Testing
- Aftoral Oral Gel, Unidea Chlorhexidine mouthwash
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Pavia
Alveolar Osteitis
Evaluations of the Effects of Tranexamic Acid and Chlorhexidine Gel on Alveolar Osteitis Incidence
This intervention is the treatment of alveolar osteitis (alveolitis) with different effects, which occurs due to the formation of clot after extraction, which is one of the most common intervals after tooth extraction.98 healthy…
- Trial name
- NCT06435832
- Testing
- Absorbable Gelatin, Chlorhexidine, Tranexamic acid
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Periodontal Diseases
Hyaluronic Gel vs Chlorhexidine in Periodontal Patients
This randomized controlled clinical trial (RCT) aims to evaluate the adjunctive efficacy of two domiciliary treatments in patients with periodontitis undergoing non-surgical periodontal therapy.
- Trial name
- NCT05312606
- Testing
- Aftoral Oral gel, Unidea Chlorhexidine digluconate mouthwash 0.20%
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Periodontology, Periodontal Disease
Evaluation of Hyaluronic Acid and Chlorhexidine Gel as an Adjunct to Minimally Invasive Non-surgical Therapy in the Treatment of Stage III and IV Periodontitis
Stage III and IV periodontitis are advanced forms of periodontal disease characterized by significant attachment loss, deep periodontal pockets, and progressive destruction of supporting periodontal tissues.
- Conditions
- Periodontology, Periodontal Disease, Periodontal Diseases, Periodontitis (Stage 3)
- Trial name
- NCT07731113
- Testing
- MINST + CHX+HA gel, MINST
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Cairo University
Head and Neck Cancer
Chlorhexidine Gel Therapy for Cariogenic Oral Microflora
The goal of this clinical research study is to find out if 1% chlorhexidine gluconate gel will decrease the amount of bacteria that causes tooth decay. Whether the gel is acceptable to patients will also be studied.
- Trial name
- NCT01036412
- Testing
- 1% Chlorhexidine Gluconate Gel, Surveys
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- M.D. Anderson Cancer Center
Orthodontic Appliance Complication, Dental Caries
Effect of Chlorhexidine Gel on Bacterial Count During Fixed Orthodontic Treatment
This study investigates the benefit of using chlorhexidine gel as an antimicrobial agent in orthodontic patient to reduce caries risk and the possible consequential effect of this use on the orthodontic brackets used for the…
- Trial name
- NCT02001311
- Testing
- Chlorhexidine gluconate
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Chronic Periodontitis
Effectiveness of Locally Delivered Morus Alba Gel on Moderate Periodontitis
Background: Periodontitis is a chronic inflammatory disease of tooth and supporting tissues with clinical signs of bone and connective tissue loss and is mediated by a combination of periodontal pathogens and host defense…
- Trial name
- NCT03475394
- Testing
- Chlorhexidine gel, Morus alba gel
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- KLE VK Institute of Dental Sciences
Infection
Study of Antimicrobial Activity of Omiganan 1% Gel vs. Chlorhexidine 2% for Topical Skin Antisepsis in Healthy Adult Subjects
The purpose of this research study is to determine if omiganan 1% gel (the investigational medication in this research study) is effective and safe when compared to chlorhexidine 2% (an FDA approved medication) for killing…
- Trial name
- NCT00608959
- Testing
- omiganan 1% gel, chlorhexidine 2% solution
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cadence Pharmaceuticals
Periodontal Diseases
Treatment of Periodontal Disease With Two Different Bioactive Gels for Home Oral Care
This study is an open-label split-mouth study in which periodontal patients will be treated in order to obtain periodontal health.
- Trial name
- NCT04781478
- Testing
- Application of Biorepair Gel, Irrigation of Chlorhexidine 1.00% gel
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Pavia
Peri-implant Mucositis
Ozoral Pro and Ozoral Gel vs Chlorhexidine Gel 1% for the Management of Peri-implant Mucositis Sites.
This is a randomized controlled clinical trial (RCT) with a split-mouth design. After signing the informed consent, patients satisfying the inclusion criteria will undergo supragingival and subgingival professional oral hygiene…
- Trial name
- NCT05254275
- Testing
- Ozoral Pro and Ozoral gel administration, Curasept chlorhexidine gel 1%
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Pavia
Peritoneal Dialysis Catheter Exit Site Infection, End Stage Renal Disease on Dialysis
Chlorhexidine Gluconate-gel Dressing for Exit Site Infection in Peritoneal Dialysis
Exit site infection (ESI) is one of the major predisposing factors to peritoneal dialysis (PD) related peritonitis. Chlorhexidine Gluconate (CHG) has been widely used for cutaneous disinfection for half a century.
- Conditions
- Peritoneal Dialysis Catheter Exit Site Infection, End Stage Renal Disease on Dialysis, Dialysis; Complications
- Trial name
- NCT06022835
- Testing
- Chlorhexidine Gluconate-gel (CHG) Dressing
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- National Healthcare Group, Singapore
Advanced Periodontitis, Stage III Periodontitis
Treatment of Periodontitis by Tulsi Gel
This study will be carried out to compare between the effect of 4%Tulsi gel and 1%Chlorohexidine gel as locally administered agents in the treatment of advanced periodontitis.
- Conditions
- Advanced Periodontitis, Stage III Periodontitis, Stage IV Periodontitis
- Trial name
- NCT06675578
- Testing
- Tulsi gel, Chlorhexidine gel
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Al-Azhar University
Drain Site Complication
The Efficacy of Chlorhexidine Gluconate Gel Dressing in Preventing Surgical Drain Site Infection
This study aims to evaluate if the application of chlorhexidine gluconate dressing on surgical drain sites can decrease drain site infection vs the standard of care (dry, sterile gauze).
- Trial name
- NCT04656145
- Testing
- 3M™ Tegaderm™ CHG Chlorhexidine Gluconate I.V. Securement Dressing
- Where
- United States
- Sponsor
- NYU Langone Health
Intracanal Medicament
Comparison of Inter-appointment Pain Reduction During Root Canal Treatment in Symptomatic Apical Periodontitis by Using Intracanal Medicaments; Chlorhexidine Gel and Single Antibiotic Paste Nitrofurantoin
This study is being conducted to find out which of two medications-Chlorhexidine Gel or Nitrofurantoin-works better in reducing pain between root canal treatment visits.
- Trial name
- NCT07198919
- Testing
- Chlorhexidine gel, Nitrofurantoin 100 MG
- Where
- Pakistan
- Volunteers
- 220 people
- Sponsor
- Altamash Institute of Dental Medicine
Impacted Third Molar Tooth
Chlorhexidine Gel Versus Alvogyl Following Surgical Extraction of Impacted Mandibular Third Molar
Background: One of the most frequent surgical operations in dentistry is the surgical extraction of the impacted mandibular third molar, which is accompanied by a sequelae of swelling, trismus, and pain.
- Trial name
- NCT06144983
- Testing
- Alvogyl, Chlorhexidine Gluconate
- Where
- Iraq
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Peri-implant Mucositis
Ozonized In-office and Domiciliary Gels vs Chlorhexidine Gel 1% for the Management of Peri-implant Mucositis Sites
This is a split-mouth randomized controlled clinical trial (RCT). After signing the informed consent, patients satisfying the inclusion criteria will undergo supragingival and subgingival professional oral hygiene of both arches…
- Trial name
- NCT05256914
- Testing
- Ozoral Pro and Ozoral gel administration, Curasept chlorhexidine gel 1%
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Periodontal Bone Loss
The Use of Chlorhexidine Gel Following EDTA Root Surface Etching as an Adjunctive to Open Flap Debridement in Treating Intra-Bony Defects
SUMMARY Chronic periodontitis is regarded as an inflammatory disease that affects the supporting tissues of teeth which could lead to bone destruction.
- Trial name
- NCT05170932
- Testing
- CHX gel 2 % + 24% EDTA
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University