Clinical trials: Chlorhexidine
Poikiloderma of Civatte, Dyschromia
Study of the 532 nm KTP Laser for the Treatment of Poikiloderma of Civatte
This study will evaluate the safety and efficacy of the Excel V 532 nm KTP laser for the treatment of dyschromia of the neck and/or chest (poikiloderma of Civatte).
- Conditions
- Poikiloderma of Civatte, Dyschromia, Pigmentation Disorders, Telangiectasia
- Trial name
- NCT01491620
- Testing
- 532 nm KTP laser
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Cutera Inc.
Vaginal Dysbiosis
Effect of FB301 on Vaginal Bacterial Profile in Women With Asymptomatic Vaginal Dysbiosis Undergoing a Mock Frozen Embryo Transfer Cycle
The goal of this clinical trial is to evaluate FB301 during a mock frozen embryo transfer (FET) cycle in pre-menopausal women aged 18 to 45 years with a prior failed FET and a defined vaginal bacterial imbalance (dysbiosis).
- Trial name
- NCT07453069
- Testing
- FB-301, Chlorhexidine (0.5%) Vaginal Cleanse
- Where
- 4 sites in United States
- Volunteers
- 30 people
- Sponsor
- Freya Biosciences ApS
Bacteriuria, Intermittent Catheterization
Open Prospective Study on Reduction of Bacteriuria Following Bladder Irrigation With Chlorhexidine
This a prospective, non-controlled, open, multi-center study evaluating the reduction of bacteriuria after bladder irrigation with chlorhexidine in spinal cord injured patients with chronic bacteriuria practicing intermittent…
- Trial name
- NCT01782404
- Testing
- Chlorhexidine
- Where
- 4 sites in Sweden
- Volunteers
- 50 people
- Sponsor
- Wellspect HealthCare
Covid19
Pilot Study to Evaluate Effect of CHX0.12/CPC 0.05 of SARS-CoV-2 Viral Load in COVID-19 Patients
Randomized, double-blind, placebo-controlled pilot study to evalaute viral load in saliva of COVID19+ patients using quantitative PCR, before and after use of active or placebo rinses
- Trial name
- NCT04563689
- Testing
- CHX0.12+CPC0.05 oral rinse (PerioAidActive Control)
- Where
- Colombia
- Volunteers
- 23 people
- Sponsor
- Dentaid SL
Coronary Artery Disease
EXCEL-II DES to Treat the Patients With de Novo Coronary Artery Lesions. (CREDIT-III)
The study aims to further assess the safety, efficacy and the performance of its delivery system of the new generation Sirolimus-eluting stent of JWMS up to five years.
- Trial name
- CREDIT-III (NCT02027870)
- Testing
- EXCEL-II biodegradable polymer sirolimus-eluting stent
- Where
- China
- Volunteers
- 625 people
- Sponsor
- JW Medical Systems Ltd
Telangiectasis, Spider Veins
Treatment of Lower Extremity Spider Veins With Excel V
The purpose of this study is to evaluate the safety and effectiveness of a new laser for the removal of unsightly spider veins on the legs.
- Trial name
- NCT01362192
- Testing
- 532 nm KTP Excel V Laser, manufactured by Cutera, Inc.
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Chronic Coronary Occlusion, Unprotected Left Main Coronary Artery Disease
EXCEL Clinical Trial
To establish the safety and efficacy of the commercially approved XIENCE Family Stent System (inclusive of XIENCE PRIME, XIENCE V, XIENCE Xpedition and XIENCE PRO [for use outside the United States [OUS] only]) in subjects with…
- Conditions
- Chronic Coronary Occlusion, Unprotected Left Main Coronary Artery Disease, Stent Thrombosis, Vascular Disease
- Trial name
- EXCEL (NCT01205776)
- Testing
- Percutaneous Coronary Intervention, CABG
- Where
- United States
- Volunteers
- 1,905 people
- Sponsor
- Abbott Medical Devices
Erythematotelangiectatic Rosacea, Papulopustular Rosacea
Excel V 532 nm KTP Laser for Treatment of Erythematotelangiectatic Rosacea & Papulopustular Rosacea
A single center prospective, randomized, controlled split face study comparing a 532nm KTP laser with a 595nm PDL for the treatment of Erythematotelangiectatic Rosacea and Papulopustular Rosacea.
- Trial name
- NCT02268474
- Testing
- 532nm KTP Laser vs 595nm Pulse Dye Laser
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Periodontitis
The Efficacy and Safety of Flurbiprofen Chip Versus Chlorhexidine Chip (Periochip®) in Therapy of Adult Chronic Periodontitis
The purpose of the study is to assess efficacy and safety of Flurbiprofen Chip versus Chlorhexidine chip (Periochip®) in therapy of adult chronic periodontitis.
- Trial name
- NCT01040286
- Testing
- Flurbiprofen, Chlorhexidine
- Where
- Israel
- Sponsor
- Dexcel Pharma Technologies Ltd.
Peri-Implantitis
The Efficacy and Safety of Chlorhexidine Gluconate Chip (PerioChip®) in Therapy of Peri-implantitis
The objective of the study is to assess the efficacy and safety of PerioChip® (Chlorhexidine gluconate chip) in the treatment of patients with Peri-implantitis.
- Trial name
- NCT02080403
- Testing
- 2.5 mg Chlorhexidine gluconate chip
- Where
- 10 sites in United States, Germany and 2 more
- Volunteers
- 290 people
- Sponsor
- Dexcel Pharma Technologies Ltd.
Bacterial Contamination
Effectiveness of Pre-Procedural CPC and Zinc Mouthwash in Reducing Dental Aerosols
This clinical trial evaluates the effectiveness of pre-procedural mouthwashes in reducing bacterial contamination in dental aerosols generated during ultrasonic scaling.
- Trial name
- NCT07880509
- Testing
- 0.09% CPC + Zinc Lactate Mouthwash, 0.2% Chlorhexidine Mouthwash, Water
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Preoperative Skin Preparation
Evaluating Safety and Effectiveness of Octenidine Dihydrochloride
The purpose of this study is to evaluate the safety and effectiveness of a topical antiseptic for preoperative skin preparation
- Trial name
- NCT03140254
- Testing
- Chlorhexidine gluconate, N,N'-(1,10-decanediyldi-1(4H)-Pyridinyl-4-ylidene)-Bis-(1-octanamine) Dihydrochloride
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- C. R. Bard
Gingivitis
Clinical Investigation of PerioGard (Test) Regimen
The objective of this three-month clinical research study is to evaluate the clinical efficacy of the PerioGard (test) regimen (0.45% SnF-HW Toothpaste, CPC-Zinc-Fluoride Mouthwash, Gummy Toothbrush) compared to the control…
- Trial name
- NCT07210138
- Testing
- PeriGuard regimen, Colgate Dental Cream regimen
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Alveolar Osteitis
Efficacy of 0.2 % Digluconate Chlorhexidine Mouthwash for Preventing Alveolar Osteitis After Third Molar Extraction
The purpose of this study is to demonstrate the efficacy of 0.2 % digluconate chlorhexidine mouthwash in the prevention of alveolar osteitis following third molar extraction and to evaluate the safety and local tolerability.
- Trial name
- NCT02382809
- Testing
- DC071
- Where
- 18 sites in Estonia, France and 2 more
- Volunteers
- 414 people
- Sponsor
- Pierre Fabre Medicament
Wound Healing Time
Enhanced Early Soft-Tissue Healing With THERAVEX Technology
randomized, double-blind clinical trial aims to evaluate the effect of different postoperative mouthwashes on early soft-tissue healing following tooth extraction
- Trial name
- NCT07580599
- Testing
- THERAVEX Total Oral Care Plus, Chlorhexidine 0.12% (Paroex), Warm saline
- Where
- Lebanon
- Volunteers
- 51 people
- Sponsor
- Biointelligent Technology Systems SL
Topical Antisepsis
Test for Pre Operative Skin Preparations
Compare 2 application techniques of ChloraPrep Swabstick--3 swabsticks at once versus 3 swabsticks used sequentially. Hibiclens applied according to the manufacturer's directions.
- Trial name
- NCT00799812
- Testing
- CHG 2% w/v & IPA 70% v/v, swabstick (3 @ once)., CHG 2% w/v & IPA 70% v/v swab applied sequentially, Aqueous CHG 4% w/v applied according to mfr's directions
- Where
- United States
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- C. R. Bard
Hypertension and Cardiovascular Risk Factors
Real Life Experience With Caduet In Patients With Cardiovascular Risk Factors
To assess the effect of single pill therapy on the management of hypertension and other cardiovascular risk factors (e.g., dyslipidemia) in Indian patients in whom the treating doctor has already considered that the…
- Trial name
- EXCEL (NCT00579254)
- Testing
- CADUET (AMLODIPINE 5 mg/ATORVASTATIN 10 mg or 20 mg)
- Volunteers
- 112 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Bacterial Vaginosis (BV)
Chlorhexidine and/or Metronidazole Plus FB301 Pre-treatment Trial
The goal of this study is to evaluate how treatment with FB301 affects the balance of vaginal bacteria in women (aged 18-45) with bacterial vaginosis after pre-treatment with either a vaginal antiseptic wash (chlorhexidine), an…
- Trial name
- NCT07481955
- Testing
- FB 301, Chlorhexidine 0.5%, metronidazole 500 mg
- Where
- 2 sites in Germany
- Volunteers
- 120 people
- Sponsor
- Freya Biosciences ApS
Periodontal Diseases
Evaluation and Comparison of Efficacy of PeriActive Mouthwash to Chlorhexidine 0.12% Mouth Rinse
Izun Pharmaceuticals has shown that PeriActive, an oral rinse containing extracts of Sambucus nigra, Echinacea purpurea, and Centella asiatica significantly reduced gingival inflammation in an experimental gingivitis model in a…
- Trial name
- NCT02987634
- Testing
- PeriActive
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Izun Pharma Ltd
Coronary Artery Disease, Myocardial Ischemia
EXCEL-II Stent Vesus EXCEL Stent to Treat the Patients With de Novo Coronary Artery Lesions.
The purpose of this Randomized Study to evaluate the safety and efficacy of the Excel-II DES compared to the EXCEL DES in the treatment of patients with de novo coronary artery lesions.
- Conditions
- Coronary Artery Disease, Myocardial Ischemia, Coronary Disease, Heart Diseases
- Trial name
- CREDIT-II (NCT02057978)
- Testing
- EXCEL DES implatation, EXCEL-II DES implantation
- Where
- China
- Volunteers
- 419 people
- Sponsor
- JW Medical Systems Ltd