Clinical trials: Chlorhexidine
Infection Secondary to Surgical Procedure
Effect of Chlorhexidine Gluconate Hair Bath on the Development of Surgical Site Infection and Time to Discharge
One of the most important preventable complications occurring in the postoperative period is surgical site infections. Surgical site infections (SSI) are infections that occur in incisions, organs or organ spaces that occur after…
- Trial name
- NCT06763211
- Testing
- Chlorhexidine Hair Bath
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- HAVVA ÇOŞKUN
Hand Washing Behavior, Hand Cleansing Behavior
Waterless Hand Cleansing With Chlorhexidine During the Perinatal Period
Background (brief): 1. Burden: Neonatal death still unacceptably high in low income countries. The common causes of neonatal death are pneumonia, sepsis and omphalitis.
- Conditions
- Hand Washing Behavior, Hand Cleansing Behavior, Chlorhexidine, Neonatal Period
- Trial name
- NCT01955317
- Testing
- Hand cleansing with chlorhexidine, Mother and neonatal health counselling
- Where
- Bangladesh
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Non-Genital Warts
Chlorhexidine and Garlic Extract as Potential Topical Virucidal Therapeutic Agents of Non-Genital Warts
Aim(s) of the Research: 1. Evaluate the efficacy and safety of topical chlorhexidine (2%) solution vs garlic extract (15%) solution in treating non-genital warts. 2.
- Trial name
- NCT06077032
- Testing
- garlic extract (15%) solution, topical chlorhexidine (2%) solution, Saline
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Healthcare Associated Infections
Daily Chlorhexidine Bathing and Infection Rates in Critically-ill Patients
Healthcare-associated infections are a major cause of morbidity among critically ill patients. Bathing critically ill patients with cloths impregnated with the broad-spectrum antimicrobial agent chlorhexidine-gluconate may…
- Trial name
- NCT02033187
- Testing
- Chlorhexidine bathing, Non-chlorhexidine bathing
- Where
- United States
- Volunteers
- 12,000 people
- Sponsor
- Vanderbilt University
Third Molars Extraction
Effect of Post-operative Chlorhexidine on Postoperative Pain and Complications After Surgical Removal of Mandibular Third Molars
This study aimed to assess the impact of postoperative chlorhexidine use on pain management following mandibular third molar removal In this prospective, randomized controlled trial,130 patients who underwent mandibular third…
- Trial name
- RITOR (NCT06880952)
- Testing
- Chlorhexidine Digluconate Mouthwash without Alcohol
- Where
- Netherlands
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Isala
Gingivitis
Miswak Efficacy Compared With Chlorhexidine
Gingivitis is a form of gum disease and is elicited by the accumulation of plaque on the tooth and the soft-tissue adjoining the tooth.
- Trial name
- MiswakChlorx (NCT04607785)
- Testing
- Miswak mouthwash group, Chlorhexidine gluconate mouthwash
- Where
- Iraq
- Volunteers
- 60 people
- Sponsor
- Al-Iraqia University
Erythematotelangiectatic Rosacea
Evaluation of the New Laser PHOTOLASE PLV-585nm for the Treatment of Rosacea
Rosacea is a frequent dermatological condition, with a chronic and disturbing evolution that is characterized by redness, permanent erythema associated with telangiectasia (visible and permanent dilatation of the small vessels).
- Trial name
- ROSAPHOTOLASE (NCT03708263)
- Testing
- Excel V 532nm (KTP) green Laser, PHOTOLASE PLV 585 nm yellow laser
- Where
- France
- Volunteers
- 1 people
- Sponsor
- University Hospital, Lille
Cesarean Section, Surgical Site Infection
Preoperative Application of Chlorhexidine to Reduce Infection With Cesarean Section After Labor
Surgical site infections (SSI) are the second most common cause of nosocomial infections accounting for 15% of all nosocomial infections among hospitalized patients and 38% of nosocomial infections in surgical patients.
- Conditions
- Cesarean Section, Surgical Site Infection, Nosocomial Infection
- Trial name
- PRACTICAL (NCT03423147)
- Testing
- 2% chlorhexidine gluconate cloth, 4% Chlorhexidine gluconate vaginal scrub
- Where
- United States
- Volunteers
- 319 people
- Sponsor
- Angela Bianco
Dental Caries, Infection, Bacterial
Evaluation of Gel and Solution of Chlorhexidine in Disinfection Root Canals of Primary Anterior Teeth.
The process of removing bacteria and their products from the root canals is an essential step that is achieved through the combination of mechanical preparation and irrigation with chemicals.
- Conditions
- Dental Caries, Infection, Bacterial, Tooth, Deciduous
- Trial name
- NCT05361278
- Testing
- Chlorhexidine solution, Activated chlorhexidine solution, Chlorhexidine gel
- Where
- Syria
- Volunteers
- 15 people
- Sponsor
- Damascus University
Apical Periodontitis, Postoperative Pain
The Effect of Using Octenidine Hydrochloride as a Final Irrigation Solution on Teeth With Asymptomatic Apical Periodontitis on Postoperative Pain and Treatment Success: A Prospective Randomized Clinical Study
This single-centre, randomized, parallel-group clinical trial compared two commonly used final irrigants in single-visit root canal treatment: octenidine dihydrochloride (OCT) and chlorhexidine (CHX).
- Trial name
- NCT07173725
- Testing
- Octenidine dihydrochloride 0.1%, Chlorhexidine 2%
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people
- Sponsor
- Bezmialem Vakif University
Surgical Site Infection, Unplanned Fracture-Related Reoperation
Pre-operative Aqueous Antiseptic Skin Solutions in Open Fractures
The prevention of infection is the single most important goal influencing peri-operative care of patients with open fractures. Standard practice in the management of open fractures includes sterile technique and pre-operative…
- Conditions
- Surgical Site Infection, Unplanned Fracture-Related Reoperation, Open Appendicular Fracture
- Trial name
- Aqueous-PREP (NCT03385304)
- Testing
- 10% povidone-iodine (1% free iodine) in purified water, 4% chlorhexidine gluconate (CHG) in purified water
- Where
- 15 sites in United States, Canada and 1 more
- Volunteers
- 1,638 people
- Sponsor
- University of Maryland, Baltimore
Telangiectasis, Spider Veins
Treatment of Lower Extremity Spider Veins With Excel V
The purpose of this study is to evaluate the safety and effectiveness of a new laser for the removal of unsightly spider veins on the legs.
- Trial name
- NCT01362192
- Testing
- 532 nm KTP Excel V Laser, manufactured by Cutera, Inc.
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Periodontal Disease
Evaluation and Comparison of the Efficacy of Triphala Mouthwash and 0.2% Chlorhexidine
The purpose of this study is to evaluate the usefulness of triphala mouthwash in comparison with the gold standard chlorhexidine in hospitalized and periodontally diseased patients.
- Trial name
- NCT01900535
- Volunteers
- 120 people
- Sponsor
- Tatyasaheb Kore Dental College
Healthcare Associated Infection, Nosocomial Infection
Red Light Photobiomodulation and Topical Disinfectants
The goal of this clinical trial is to evaluate the potential effects of photobiomodulation when used with topical disinfectants in the anterior nares of healthy adults.
- Conditions
- Healthcare Associated Infection, Nosocomial Infection, Surgical Site Infection
- Trial name
- NCT05797818
- Testing
- Methylene Blue Only, Chlorhexidine Gluconate Only, Methylene Blue + Chlorhexidine Gluconate
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ondine Biomedical Inc.
Surgical Site Infection
Prevention of Surgical Site Infection After Cesarean Delivery
There are approximately 1.4 million cesarean deliveries in the United States each year, and an average of 1250 elective cesarean deliveries each year at the Brigham and Women's Hospital (BWH) in Boston, Massachusetts.
- Trial name
- CAPISSI (NCT02027324)
- Testing
- Chlorhexidine-alcohol group, Povidone-Iodine Group
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Plaque Score, Gingival Health
Effectiveness of Herbal vs Chlorhexidine Mouthwashes in Improving Oral Health in Schoolchildren
Dental plaque and gingivitis are common oral health problems among school children. Mechanical plaque control, such as tooth brushing, is essential but may be insufficient for maintaining optimal oral hygiene.
- Conditions
- Plaque Score, Gingival Health, Streptococcus Mutans
- Trial name
- NCT07309679
- Testing
- Chlorhexidine Digluconate 0.2% Mouthwash, Pomegranate Peel Extract Mouthwash, Neem Extract Mouthwash
- Where
- Egypt
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Satisfaction, Product Quality
Surgeons' Satisfaction With Two Types of Tinted Chlorhexidine Applicators (Chloraprep® and Nex Clorex 2%)
The development of surgical site infections (SSI) in clean-contaminated surgery is regarded as being preventable. Known to be effective in the prevention of surgical site infection are the adequate sterilization of the surgical…
- Trial name
- NCT03508492
- Testing
- Surgical tinted Chloraprep® applicators, Surgical tinted Nex Clorex 2% applicators
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cristina Fernandez Perez
Infectious Disease Transmission
Effectiveness of Chlorhexidine Bathing in the Neonatal Intensive Care Unit
This is a prospective, controlled; crossover study of daily bathing with no-rinse, 2% chlorhexidine gluconate (CHG) impregnated washcloths versus bathing with water/soap or water according to gestational age and weight (e.g.
- Trial name
- NCT02537964
- Testing
- washcloths impregnated with 2% chlorhexidine gluconate
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Shaare Zedek Medical Center
Human Microbiome
Cultures Before and After Decolonization in Community Dwelling Adults With Current S. Aureus Colonization
The investigators propose to study the microbiome of the nose, throat and three skin sites in a population without current exposure to the healthcare environment: 80 community dwelling adults.
- Trial name
- NCT04222699
- Testing
- Mupirocin calcium ointment, 2%, Topical Chlorhexidine, 4%
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Frenectomy, Erbium YAG Laser
Retrospective Frenectomy Analysis: Techniques and Adjunctive Antimicrobials
The frenulum is a mucosal fold that connects the lips and cheeks to the alveolar mucosa or gingiva, with abnormal attachments-particularly papillary and papillary-penetrating types-linked to clinical issues such as gingival…
- Conditions
- Frenectomy, Erbium YAG Laser, Antimicrobial Agent
- Trial name
- NCT07054021
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi