Clinical trials: Chlamydia
Chlamydial Infection, Gonococcal Infection
Clinical Evaluation of the Click Sexual Health Test for the Detection of Neisseria Gonorrhoeae (NG), Trichomonas Vaginalis (TV), and Chlamydia Trachomatis (CT) in Women
This study is a multi-center study with a minimum of three CLIA-waived intended operator sites in the United States in which prospectively self-collected vaginal specimens obtained from subjects who are symptomatic or…
- Conditions
- Chlamydial Infection, Gonococcal Infection, Trichomoniasis
- Trial name
- NCT04098900
- Testing
- Click Sexual Health Test
- Where
- 5 sites in United States
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- Visby Medical
Chlamydial Infection
YCFM (Youth Correctional Facilities Males)
The proposed study is a single center (with multiple long-term YCFs) treatment trial of the CDC-recommended azithromycin regimen (1 gm PO once) for chlamydia in males.
- Trial name
- NCT03249935
- Testing
- Azithromycin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Chlamydia Trachomatis Genital Infection, Chlamydia Trachomatis Infection of Anus and Rectum
Are Rectal and Genital Chlamydia Trachomatis Infections in Women Related to Anal Sex, Autoinoculation / Contamination
Chlamydia trachomatis is the most common cause of sexually transmitted bacterial infection in Sweden, an infection that is notifiable according to the Communicable Diseases Act and the Communicable Diseases Ordinance.
- Trial name
- NCT04030949
- Testing
- No new interventions will be applied. MLST and MLVA even vPCR are tests already existing, tested and without any known adverse effects for the participants
- Where
- 2 sites in Sweden
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Region Östergötland
HIV, Sexual Behavior
Love, Sex & Choices: A Web Series on Mobile Devices to Reduce Black Women's HIV Risk
This study tests a 12-episode Internet-based, guide enhanced Love, Sex, \& Choices (LSC) HIV prevention soap opera video series for smartphones or computers, in a randomized clinical trial among predominately at-risk African…
- Conditions
- HIV, Sexual Behavior, Women's Role, Risk Behavior
- Trial name
- LSC (NCT02493647)
- Testing
- Love, Sex, & Choices
- Where
- United States
- Volunteers
- 814 people
- Sponsor
- Northeastern University
Reproductive Tract Infections
Evaluation of Immediate v. Delayed CT/NG Test for Treatment in the ED
The purpose of this study is to determine if immediate availability of GeneXpert® CT/NG test results reduces the overtreatment rate for ED patients with suspected gonorrhea or chlamydia and to assess changes in clinician…
- Trial name
- NCT01989130
- Testing
- Roche AMPLICOR CT/NG, Cepheid Xpert CT/NG Test
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- George Washington University
Neisseria Gonorrhoeae Infection, Chlamydia Trachomatis Infection
Performance of Nucleic Acid Amplification Tests for the Detection of NG and CT
The purpose of this study was to use participant samples to simultaneously evaluate three nucleic acid amplification tests (NAATs) diagnostic platforms.
- Conditions
- Neisseria Gonorrhoeae Infection, Chlamydia Trachomatis Infection, Sexually Transmitted Infections
- Trial name
- pNAAT (NCT02870101)
- Testing
- Nucleic acid amplification test 1 for NG and CT, Nucleic acid amplification test 2 for NG and CT, Nucleic acid amplification test 3 for NG and CT
- Where
- 9 sites in United States
- Volunteers
- 2,767 people, healthy volunteers welcome
- Sponsor
- Duke University
Gonorrhea, Chlamydia
Safer Sex Program for Young African-American Men
To evaluate the efficacy of the adapted program a randomized controlled trial enrolling 620 eligible African American men who have sex with men (MSM) will be conducted.
- Conditions
- Gonorrhea, Chlamydia, Trichomoniasis, Syphilis
- Trial name
- NCT01439503
- Testing
- Intervention
- Where
- United States
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- Richard Crosby
Gonococcal Infection, Chlamydia Infections
Screening of Gonococcal and Chlamydial Infections in the Third Trimester
Untreated maternal infection with gonorrhea and/or chlamydia can have serious complications in pregnancy and the neonatal period.
- Trial name
- NCT03073538
- Volunteers
- 1,691 people
- Sponsor
- Unity Health Toronto
Gonorrhea, Chlamydia
Cepheid Rectal Sample Validation Study
The purpose of this study is to validate Xpert CT/NG for the detection of CT and GC in rectal samples as part of the PA DOH and CLIA requirements.
- Conditions
- Gonorrhea, Chlamydia, Trichomonas
- Trial name
- NCT02099760
- Testing
- STD testing (GC/Ct/trich)
- Where
- 2 sites in United States
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Arthritis, Reactive, Reiter Disease
Combination Antibiotic Treatment for Reactive Arthritis Caused by Chlamydia Bacteria
Reactive arthritis, also known as Reiter's syndrome, is a form of arthritis that occurs as a reaction to an infection elsewhere in the body. It is characterized by inflammation of the joints, tendons, urogenital tract, and eyes.
- Trial name
- NCT00351273
- Testing
- Doxycycline and Rifampin, Azithromycin and Rifampin
- Where
- 3 sites in United States, Canada
- Volunteers
- 42 people
- Sponsor
- University of South Florida
Gonorrhoea of Rectum, Chlamydia of Rectum
STI Screening as a Combined HIV Prevention Platform for MSM in Peru
The investigators propose to develop and pilot an HIV prevention intervention based on rectal STI testing, counseling, and treatment for MSM in Peru.
- Conditions
- Gonorrhoea of Rectum, Chlamydia of Rectum, HIV Infections
- Trial name
- NCT03010020
- Testing
- PCC, Traditional Counseling
- Where
- Peru
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Pre-Eclampsia
Impact of Antichlamydial Treatment on the Rate of Preeclampsia
This randomized, double blinded controlled trial included 1200 healthy primigravidae who attended an outpatient clinic at 16-20weeks of pregnancy.
- Trial name
- NCT03233880
- Testing
- Azithromycin 1gm
- Where
- Egypt
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Streptococcus Pneumonia, Haemophilus Influencae
Etiology of Community Acquired Pneumonia
The proposed study aims to provide current information, etiology and outcome of community-acquired pneumonia (CAP), risk factors for for CAP in isolates of Streptococcus pneumoniae and Haemophilus influencae, Mycoplasma…
- Conditions
- Streptococcus Pneumonia, Haemophilus Influencae, Mycoplasma Pneumonia, Chlamydia Pneumonia
- Trial name
- CAP (NCT00471757)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Pittsburgh
Chlamydia Trachomatis Infection
Transmission of Genital and Extra-genital Chlamydia Trachomatis Infections in Women
Multicenter prospective cohort study in Chlamydia trachomatis positive women after regular treatment to understand the transmission of anorectal CT infections.
- Trial name
- FemCure (NCT02694497)
- Testing
- Chlamydia care as usual
- Where
- Netherlands
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Chlamydia Infections
Partner Notification for Chlamydia in Primary Care
The purpose of this study was to compare the effectiveness of partner notification by general practice nurses with referral to a specialist clinic for people with genital chlamydia diagnosed in a community setting.
- Trial name
- NCT00112255
- Testing
- Practice nurse-led partner notification, Referral to specialist genitourinary clinic
- Where
- 2 sites in United Kingdom
- Volunteers
- 214 people
- Sponsor
- University of Bristol
Attitude, Sexual Behavior
Theater in School Sex Education - a Randomized Controlled Study
The study evaluated if interactive theater in school sex education affects student knowledge, attitudes and behavior regarding condom use.
- Conditions
- Attitude, Sexual Behavior, Condom Use, Prevention
- Trial name
- NCT03374696
- Testing
- SAFETY, Standard education
- Volunteers
- 826 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Chlamydia, Gonorrhea
Detection of Chlamydia (CT) and Gonorrhea (NG)
To evaluate the illumigene Chlamydia and illumigene Gonorrhea assays, using the illumipro-10, with male urine, female urine, physician-collected (medical professional) endocervical swabs and self-collected vaginal swabs taken…
- Trial name
- NCT02055742
- Testing
- illumigene CT and NG assays, illumipro-10
- Where
- 3 sites in United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Meridian Bioscience, Inc.
Gonorrhea, Chlamydia Infections
Risk Assessment of Long-Haul Truck Drivers
International studies have repeatedly documented a substantial prevalence of sexual risk behaviors and high rates of human immunodeficiency virus (HIV) and other sexually transmitted infections (STI) ranging from 5%-56% amongst…
- Conditions
- Gonorrhea, Chlamydia Infections, Hepatitis B, Hepatitis C
- Trial name
- NCT00381992
- Where
- United States
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Trachoma, Chlamydia
Tripartite International Research for the Elimination of Trachoma
Mass antimicrobial administrations have been remarkably successful in reducing the prevalence of the ocular strains of Chlamydia that cause trachoma.
- Trial name
- TIRET (NCT01202331)
- Testing
- mass treatment with oral azithromycin
- Where
- Ethiopia
- Volunteers
- 29,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Uncomplicated Urogenital Gonorrhea
Efficacy and Safety Study of Oral Solithromycin Compared to Intramuscular Ceftriaxone Plus Oral Azithromycin in the Treatment of Patients With Gonorrhea
This study will compare a single dose of oral solithromycin to the standard of care (intramuscular ceftriaxone plus oral azithromycin) in the treatment of patients with urogenital gonorrhea.
- Trial name
- SOLITAIRE-U (NCT02210325)
- Testing
- solithromycin, ceftriaxone, azithromycin
- Where
- 5 sites in United States, Australia
- Volunteers
- 264 people
- Sponsor
- Melinta Therapeutics, Inc.