Clinical trials: Childhood Cancer Survivors
Survivors of Childhood Cancer, Acute Lymphoblastic Leukemia, Childhood
Feasibility and Acceptability of Remote Saliva Collection
The purpose of this study is to evaluate the practicality and acceptability of collecting biological samples and health information from childhood survivors of acute lymphoblastic leukemia (ALL) and their siblings.
- Trial name
- NCT07884474
- Testing
- Salivary Cortisol Collection, Blood Biomarker Collection, Hair Cortisol Collection
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Cancer Survivor, Childhood Acute Lymphoblastic Leukemia in Remission
Culturally Adapted Parenting Intervention for Spanish-Speaking Parents in Improving Outcomes of Younger Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia Survivors at Risk for Late Neurocognitive Effects
This pilot clinical trial studies a culturally adapted skills training and educational intervention in guiding parents of younger acute lymphoblastic leukemia (ALL) or acute myeloid leukemia (AML) survivors at risk for long-term…
- Conditions
- Cancer Survivor, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Cognitive Side Effects of Cancer Therapy
- Trial name
- NCT02559557
- Testing
- Educational Intervention, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Childhood Cancer, Childhood Cancer Survivors
Proof-of-Concept Testing of the Cardiovascular Health Equity Through Food (CHEF) Intervention in Childhood Cancer Survivors
The goal of the Cardiovascular Health Equity Through Food (CHEF) program is to make it easier for participants and families to cook and eat healthy foods during and following childhood cancer treatment with the long-term goal of…
- Trial name
- CHEF (NCT06609473)
- Testing
- CHEF Intervention Program
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Dana-Farber Cancer Institute
Childhood Cancer Survivors
Pain and Sleep Disturbances in Children Living Beyond Cancer: A Case-Control Study
Children living beyond cancer (CBC) represent a unique and growing population of young people in need of long-term clinical support.
- Trial name
- NCT07120646
- Testing
- Questionnaire, actigraphy measurement and sleep diary
- Where
- 2 sites in Belgium
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Survivors of Childhood Cancer, Bladder Dysfunction
Impact of Chemotherapy on Urinary Biomarkers and Non-Invasive Urodynamics in Children
The over-arching aim of this study is to evaluate the effects of two specific anti-cancer chemotherapies, vincristine and doxorubicin, on bladder function and urine composition.
- Trial name
- NCT04993859
- Testing
- Non-invasive Urodynamic Test (niUDS), Urinary proteomic screen, Dysfunctional Voiding Symptom Score Survey (DVSS)
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- University of Colorado, Denver
Childhood Cancer Survivors
A Study of Time-Restricted Eating in Childhood Cancer Survivors
This study will look at whether motivational sessions (including regular calls with a trained health coach) in combination with time-restricted eating (TRE) is an effective way to achieve weight loss and lower cardiometabolic…
- Trial name
- NCT07009288
- Testing
- Children's Oncology Group Heart Health Link, Monthly weights, Fasting
- Where
- 4 sites in United States
- Volunteers
- 300 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Childhood Cancer Survivor, Chronic Pain
Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Cancer: A Randomized Clinical Trial
The purpose of the study is to determine if an adapted mobile cognitive behavioral therapy (CBT) app (WebMAP Onc) is more effective than standard pain education in reducing chronic pain and improving daily functioning in…
- Trial name
- ADAPTED2 (NCT07160621)
- Testing
- Cognitive Behavioral Therapy (CBT), Education, Questionnaires
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- St. Jude Children's Research Hospital
Survivors of Childhood Cancer, Substance Use
Feasibility of Incorporating a Standardized Substance Use Measure With Linked-Brief Intervention Into Routine Psychosocial Care of Adult Childhood Cancer Survivors
The ASSIST Study is designed to explore whether a brief, evidence based substance use screening and counseling approach can be easily integrated into routine survivorship care at St. Jude Children's Research Hospital.
- Trial name
- NCT07516301
- Testing
- WHO ASSIST v3.1 Screening with Feedback, ASSIST Linked Brief Intervention (10 Step Motivational interviewing (MI)/FRAMES), WHO ASSIST v3.1 Screening (No Feedback)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- St. Jude Children's Research Hospital
Survivors of Childhood Cancer
Behavioral Reinforcement Intervention for Greater Health Trajectories After Childhood Cancer (BRIGHT)
Survivors of childhood cancer have a substantially increased risk of long-term health problems in adulthood, including cardiovascular disease, metabolic disorders, psychological morbidity, and impaired health-related quality of…
- Trial name
- BRIGHT (NCT07384286)
- Testing
- Lifestyle Management
- Where
- Sweden
- Volunteers
- 900 people
- Sponsor
- Vastra Gotaland Region
Cancer Risk, Cancer Predisposition Syndrome
InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer
This research study is creating a way to collect and store specimens and information from participants who may be at an increased risk of developing cancer, or has been diagnosed with an early phase of a cancer or a family member…
- Conditions
- Cancer Risk, Cancer Predisposition Syndrome, Hereditary Cancer Prediction, Childhood Cancer Survivors
- Trial name
- NCT05463796
- Testing
- Samples
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Survivor of Childhood Cancer, Insomnia
Transcutaneous Auricular Vagus Nerve Stimulation for Insomnia in Survivors of Childhood Acute Lymphoblastic Leukemia
This pilot study will assess the usefulness and potential effectiveness of using transcutaneous auricular vagus nerve stimulation (tVNS) for treating insomnia in adult survivors of childhood acute lymphoblastic leukemia (ALL).
- Conditions
- Survivor of Childhood Cancer, Insomnia, Acute Lymphoblastic Leukemia (ALL)
- Trial name
- NCT07191119
- Testing
- Soterix tVNS device, Sleep Quality, Neurocognitive and mental health outcomes
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- St. Jude Children's Research Hospital
Adolescent Cancer Survivors, Childhood Cancer Survivors
IMpact of Mind-body Therapies (HYpnosis and Relaxation) on Anxiety in Children, Adolescents and Young Adults Who Had Been Treated in ONcology. Multicenter Study.
In France today, it is estimated that one in 850 people aged between 20 and 45 has been cured of cancer in childhood. Some descriptive studies have established that cancer diagnosis and treatment can affect psychological health…
- Conditions
- Adolescent Cancer Survivors, Childhood Cancer Survivors, Anxiety
- Trial name
- HARMONY-Impact (NCT07380672)
- Testing
- 10 mind-body therapy sessions (hypnosis or relaxation, depending on the patient's choice), 9 sessions of standard psychological care
- Where
- 5 sites in France
- Volunteers
- 558 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Generalized Anxiety, Introspective & Anxiety-Prone Patient
Validation of a Rapid Screening Tool for Anxiety-depressive Disorders in Children, Adolescents and Young Adults Treated in Oncology. Multicenter Study.
In France today, it is estimated that one in every 850 people aged between 20 and 45 is a childhood cancer survivor (CCS), equivalent to around 40,000 to 50,000 people.
- Conditions
- Generalized Anxiety, Introspective & Anxiety-Prone Patient, Depression, Anxiety, Survivors of Childhood Cancer
- Trial name
- HARMONY-Tool (NCT07117058)
- Testing
- New rapid screening tool for anxiety and depressive disorders, SCARED-R-51 (Screen for Child Anxiety Related Emotional Disorders-Revised), HADS (Hospital Anxiety and Depression Scale)
- Where
- 7 sites in France
- Volunteers
- 545 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Childhood Cancer Survivors
Overnight Fasting After Completion of Therapy: The OnFACT Study
The purpose of this study is to test whether regularly not eating for at least 14 hours overnight ("intermittent fasting") is feasible and can improve blood sugar.
- Trial name
- NCT03523377
- Testing
- prolonged overnight fasting, usual care
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Survivors of Childhood Cancer
Complementary Behavioral Interventions To Remediate Cognitive Impairment or Emotional Distress in Cancer Survivors
Childhood cancer survivors are at risk for accelerated aging due to the specific treatments they have received to cure their cancer.
- Trial name
- COPILOT (NCT06989463)
- Testing
- 12 Week Exercise Intervention, Cognitive Training Intervention, Mindfulness practice intervention
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- St. Jude Children's Research Hospital
Childhood Cancer Survivors
eQuoL Effectiveness Study
This prospective cohort study aims to evaluate the implementation and impact of the MyCare eQuoL digital tool across nine clinical sites in Europe: Italy, France, Hungary, Germany, Switzerland, Belgium, Slovenia, Spain, and…
- Trial name
- NCT07541183
- Testing
- Psychosocial support trought a web app
- Volunteers
- 200 people
- Sponsor
- Istituto Giannina Gaslini
Childhood Cancer Survivors
Lifestyle Medicine Adherence, Mental Wellbeing, and Quality of Life in Pediatric Oncology in Ecuador
Background: Advances in pediatric oncology have significantly improved survival rates; however, many children and adolescents with cancer experience persistent physical and psychological challenges that negatively affect their…
- Trial name
- NCT07490548
- Where
- 4 sites in Ecuador
- Volunteers
- 62 people
- Sponsor
- Universidad de Especialidades Espiritu Santo
Childhood Cancer, Cancer Survivors
Diaphragm Structure and Function in Childhood Cancer Survivors
The purpose of this research is to study the feasibility of a specific training program for the breathing muscles (inspiratory muscle training) and the effects on how breathing is regulated during exercise in childhood cancer…
- Trial name
- NCT06205251
- Testing
- POWERbreathe Plus IMT
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Maryland, Baltimore
School Attendance, Academic Level
SchoolCare: A Social Intervention Introducing Telepresence Robots and School Navigation to Reduce School Fragmentation for Children Undergoing Cancer Treatment
Advances in pediatric cancer treatment have led to significant improvements in survival rates, where 5-year survival now exceeds 85%.
- Conditions
- School Attendance, Academic Level, Childhood Cancer Survivors, Social Well-being
- Trial name
- SchoolCare (NCT07398677)
- Testing
- Telepresence robot, School Navigator, Teleteaching and technical support
- Where
- 3 sites in Denmark
- Volunteers
- 128 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Childhood Cancer Survivors, Cardiotoxicity
Impact of Exercise Intensity on Cardiac Health in Young Adult Survivors of Childhood Cancer: The PULSE Trial
This trial aims to evaluate the impact of exercise intensity on cardiac health in young adult survivors of childhood cancer previously treated with anthracyclines.
- Conditions
- Childhood Cancer Survivors, Cardiotoxicity, Cardiovascular Diseases, Anthracycline-induced Cardiotoxicity
- Trial name
- PULSE (NCT07442578)
- Testing
- HIIT Exercise Program, MICT Exercise Program
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dana-Farber Cancer Institute