Clinical trials: Child Allergy
Asthma
Prevention of Asthma Exacerbations Using Dupilumab in Urban Children and Adolescents
This is a multi-center, double-blind, placebo-controlled, randomized trial of dupilumab adjunctive therapy for prevention of asthma exacerbations in urban children and adolescents with T2-high exacerbation-prone asthma.
- Trial name
- PANDA (NCT05347771)
- Testing
- Dupilumab
- Where
- 8 sites in United States
- Volunteers
- 240 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Asthma
Telemedicine Education for Rural Children With Asthma
The investigators will implement an interactive school-based telemedicine education program for rural low-income, minority children with asthma, their caregivers, and school nurses in the Delta region of Arkansas.
- Trial name
- NCT00964301
- Testing
- Telemedicine Education, Usual care
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Self Efficacy, Asthma
The Effect of Online Peer and Adult Education Given to Adolescents With Allergic Asthma
Objectives: To examine the effect of interactive online education given by peers or adults on anxiety, self-efficacy, quality of life, and disease knowledge and management in adolescents with allergic asthma in the 10-14 age…
- Conditions
- Self Efficacy, Asthma, Asthma in Children
- Trial name
- NCT06045312
- Testing
- education
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Aydin Adnan Menderes University
Severe Asthma
Follow-up of Children With Severe Asthma at Adult Age
Most of clinical cohorts focused on the course of asthma over time and on the different phenotypes of asthma have investigated children and adults separately. The passage from childhood to adulthood is scarcely explored.
- Trial name
- S2AEA (NCT05032209)
- Testing
- follow-up of children with severe asthma in adulthood
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Allergy
Direct Oral Challenges in Private Practice Setting to Delabeling Children With Beta-lactam Allergy
The purpose of this study is to demonstrate the feasibility of direct oral challenge performed in private practice setting for children with suspected benign delayed allergy to beta-lactams.
- Trial name
- Betalactaville (NCT07002814)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorder
Schema, Emotion, and Behavior Therapy for Children
The study is a randomized controlled trial to examine the efficacy of individual cognitive behavioral therapy (CBT) relative to a standard community treatment, in youngsters with autism spectrum disorder (ASD).
- Trial name
- SEBASTIEN (NCT01784263)
- Testing
- Individual Cognitive Behavioral Therapy, Standard Community Treatment
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, Los Angeles
Asthma, Wheeze
The Development of Novel Clinical Tests to Diagnose and Monitor Asthma in Preschool Children
The study will ascertain the ability of preschool lung function tests to distinguish healthy children from those with wheeze, and to differentiate phenotypes of wheezy children (high and low risk for asthma as defined by API) in…
- Conditions
- Asthma, Wheeze, Obstructive Sleep Apnea, Food Allergy
- Trial name
- WheezyER (NCT02743663)
- Testing
- Bronchodilator response, Allergy Skin Test, Multiple-Breath Washout
- Where
- Canada
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Allergic Rhinitis
Nasal Budesonide Efficacy on Nasal FeNO in Children With Allergic Rhinitis
In clinical trials for treatment of allergic rhinitis a significant reduction of the total symptom score compared to baseline has been demonstrated by using nasal budesonide.Previous results in adults show that the assessment and…
- Trial name
- NCT02409563
- Testing
- Budesonide nasal spray (100 mcg bid), Budesonide nasal spray (50 mcg bid
- Where
- Italy
- Volunteers
- 39 people
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Allergic Rhinitis Due to Grass Pollen
The Influence of Nonspecific Immunostimulation on Changes in the Concentration of iNKT Cells
The aim of the study is to assess the effect of polyvalent mechanical bacterial lysate (PMBL, Ismigen) on the clinical course of grass pollen-induced allergic rhinitis (using: total nasal symptom score, visual analogue scale…
- Trial name
- NCT04802616
- Testing
- Ismigen
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Medical University of Lublin
Cough Variant Asthma
Non-Interventional Study of Cough Variant Asthma Treatment With Pulmicort®Respules® in Children Outpatients
This open label, non-interventional study is to show the efficacy of Pulmicort®Respules® in cough variant asthma in patient aged 5-year old or younger in outpatient department
- Trial name
- PUL NIS (NCT00660114)
- Where
- 32 sites in China
- Volunteers
- 914 people
- Sponsor
- AstraZeneca
Asthma
Early Diagnosis of Asthma in Young Children
The overall aim of the study is an early asthma diagnosis in young children by the use of non-invasive biomarkers of airway inflammation /oxidative stress in exhaled air, and early lung function measurements
- Trial name
- NCT00422747
- Testing
- beclomethasondipropionate
- Where
- Netherlands
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Bronchial Asthma
Effect of Addition of Oral Montelukast to Standard Treatment in Acute Moderate to Severe Asthma in Children
Available evidences show a role of oral montelukast in acute asthma. Safety of oral montelukast is well established in children, as evidenced by use of oral montelukast in long term management of asthma.
- Trial name
- Montelukast (NCT00565955)
- Testing
- montelukast
- Where
- India
- Volunteers
- 116 people
- Sponsor
- All India Institute of Medical Sciences
Asthma in Children
BiPAP in Pediatric Moderate to Severe Asthma Randomized Control Trial
The goal of this clinical trial is to study if starting bi-level positive airway pressure (BiPAP), a mask that gives pressure to the lungs, works well for children in the emergency department with moderate to severe asthma…
- Trial name
- NCT05848115
- Testing
- Bi-level Positive Airway Pressure
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of Colorado, Denver
Food Allergy, Food Allergy in Children
Effect of Omalizumab in the Skin of Food Allergy Patients
The goal of this interventional study is to evaluate whether skin barrier abnormalities occur in subjects with a food allergy, as determined by positive oral food challenge (OFC).
- Trial name
- NCT06618963
- Testing
- Omalizumab Injection
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Jewish Health
Asthma
Efficacy of Ciclesonide Inhaled Once Daily Versus Other Corticosteroids Used for Treatment of Mild Asthma in Children (4 to 11 Years) (BY9010/CA-101)
The aim of this study is to compare the efficacy of ciclesonide with respect to reduction of the number of asthma exacerbations in children with mild persistent asthma.
- Trial name
- POPCICLE (NCT00163293)
- Testing
- Ciclesonide
- Where
- 7 sites in Canada, Hungary and 1 more
- Volunteers
- 240 people
- Sponsor
- AstraZeneca
Asthma
Kids 2 Be & Breathe: A Study on the Use of Yoga and Mindfulness in Children With Severe Asthma (K2B2)
This proposed pilot study will examine the tolerability, feasibility, acceptability, and preliminary effects of a gentle yoga intervention "Kids 2 Be \& Breathe" (K2B2; a manualized 30 minute gentle yoga and mindfulness session…
- Trial name
- K2B2 (NCT03752164)
- Testing
- Yoga and Mindfulness Skills
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Virginia Commonwealth University
Environmental Exposure
Effects of Pesticide Exposure on Neurodevelopment/Growth/Respiratory Health
Exposure and health study of pesticide and allergen exposures to pregnant women and children. Intervention study is planned after assessment is completed.
- Trial name
- NCT00021658
- Testing
- Pesticide application procedures
- Where
- United States
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Atopic Dermatitis
A Study of Baricitinib (LY3009104) in Children and Adolescents With Atopic Dermatitis
The reason for this study is to see if the study drug called baricitinib works and is safe in children and teenage participants with atopic dermatitis.
- Trial name
- BREEZE-AD-PEDS (NCT03952559)
- Testing
- Baricitinib, Topical corticosteroid
- Where
- 78 sites in Argentina, Australia and 15 more
- Volunteers
- 516 people
- Sponsor
- Eli Lilly and Company
Asthma
Montelukast Added to Standard Therapy for Acute Asthma in Children Age 6-14 Years
Oral montelukast is helpful in chronic asthma. The purpose of this pediatric study was to investigate whether the addition of oral montelukast to standard therapy for acute asthma exacerbations results in further improvement in…
- Trial name
- NCT00353184
- Testing
- Montelukast 5-mg orally added to standard therapy
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Washington University School of Medicine
Henoch-Schoenlein Purpura
The Research of Standard Diagnosis and Treatment for Severe HSP in Children
This study is performed to evaluate the efficacy and safety of various measures in the treatment of severe HSP in children.
- Trial name
- NCT02540720
- Testing
- Dexamethasone, Gamma globulin, Hemoperfusion
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Nanjing Children's Hospital
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