Clinical trials: Chest Tube
Lung Diseases, Interstitial, Pulmonary Nodule, Solitary
Chest Tube After a Video-assisted Thoracoscopic Surgery Pulmonary Wedge Resection
After performing VATS pulmonary wedge resections, a chest tube is routinely left in the pleural cavity to drain possible air leaks and fluid accumulations.
- Trial name
- NOTUBE (NCT00841750)
- Testing
- Do not leave a chest tube in the pleural cavity., Do leave a chest tube in the pleural cavity.
- Where
- 3 sites in Colombia
- Volunteers
- 100 people
- Sponsor
- Fundación Oftalmológica de Santander Clínica Carlos Ardila Lulle
Pleural Effusion, Pneumothorax
Suturing With U-Technique Versus Un-Reapproximated Wound Edges During Removal of Closed Thoracostomy Tube Drain
The study will be carried out by the principal investigator and his team at the Division of Cardiovascular and Thoracic Surgery of the Department of Surgery, College of Medicine, University of Ibadan and the University College…
- Conditions
- Pleural Effusion, Pneumothorax, Chest Trauma, Video-assisted Thoracoscopic Surgery
- Trial name
- SUTURE (NCT04193241)
- Testing
- Closure of chest tube wound
- Where
- Nigeria
- Volunteers
- 142 people
- Sponsor
- University of Ibadan
Mediastinal Tumor
Totally no Tube (TNT) Uniportal Video-assisted Thoracoscopic Surgery (VATS) VS Traditional Uniportal VATS for Mediastinal Tumor
TNT surgery is a new area of exploration and evolution in thoracic minimal invasive surgery. TNT Uniportal Video-assisted Thoracoscopic Surgery (VATS) has become popular during mediastinal tumors resection.
- Trial name
- NCT03537430
- Testing
- TNT uniportal VATS mediastinal tumor resection, Traditional uniportal VATS mediastinal tumor resection
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Xueying Yang
Double-lumen Tube, One-lung Ventilation (OLV)
The Role of Existing Formulas in the Double-lumen Tube in Thoracic Surgery Anesthesia
In most clinical scenarios, left DLT is preferred for one-lung ventilation because of its anatomical ease of placement; these tubes allow separate ventilation of both lungs.
- Conditions
- Double-lumen Tube, One-lung Ventilation (OLV), Thoracic Anesthesia
- Trial name
- NCT07191002
- Testing
- placement depth of the double lumen tube
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Patients Undergoing Elective Thoracic Surgery Requiring Obligatory Single-lung Ventilation During Surgery
Prospective, Randomized Clinical Trial Evaluating the ETView Double-Lumen Tube
No prospective randomized clinical trial assessed the performance of this new device in a clinical setting. Consequently the aim of this study is to determine clinical performance of this new device compared with conventional…
- Trial name
- NCT01807676
- Testing
- ET View Double Lumen Tube, conventional Double Lumen Tube
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Malignant Pleural Effusion
Tunneled Pleural Catheter in Partially Entrapped Lung
An open randomized, prospective, single center; parallel group trial to compare efficiency and safety of PleurX-Pleural Catheter versus standard surgical treatment in patients with malignant pleural effusion and partial…
- Trial name
- NCT00637676
- Testing
- VATS, Talc-Pleurodesis, tunneled pleural drainage, VATS, Talc-pleurodesis
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Heidelberg University
Pleural Effusion
Virtual Reality for Satisfaction and Tolerability During Intercostal Chest Drain Insertion: A Headset-Based Randomized Controlled Trial
Intercostal chest drain (ICC) insertion is a common procedure done worldwide to treat and diagnose pleural disease. It is used to evacuate fluid, blood, or air in the cavity from a myriad of causes namely pleural effusions of…
- Trial name
- VR-STICH (NCT06247800)
- Testing
- Virtual Reality Device, Without virtual reality
- Where
- Malaysia
- Volunteers
- 72 people
- Sponsor
- National University of Malaysia
Pleural Effusion, Video Assisted Thoracic Surgery
Safety and Efficacy of Coaxial Smart Drain (Redax TM) in Uniportal-VATS
The aim of the study is to evaluate efficacy and safety of "Smart Coaxial drain" (Redax TM, Poggio Rusco, Mantova, Italia) in terms of total amount of effusion drained, incidence of residual effusion at Chest X-Ray and patient's…
- Conditions
- Pleural Effusion, Video Assisted Thoracic Surgery, Chest Tubes
- Trial name
- NCT06036667
- Testing
- 28Fr "coaxial smart drain" chest tube
- Where
- Italy
- Volunteers
- 178 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
One-lung Ventilation
EZ Blocker Versus Left Sided Double-lumen Tube
Lung isolation is used to achieve one lung ventilation to facilitate thoracic surgery. Two methods are commonly used, a double lumen tube (DLT) or a bronchial blocker introduced through a single lumen tube.
- Trial name
- NCT01073722
- Testing
- Placement of double lumen tube for one-lung ventilation, Placement of EZ- Blocker for one-lung ventilation
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Radboud University Medical Center
Advanced Malignant Solid Neoplasm, Clinical Stage III Cutaneous Melanoma AJCC v8
Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies
This phase Ib trial studies the side effects and best dose of selinexor when given together with several different standard chemotherapy or immunotherapy regimens in treating patients with malignancies that have spread to other…
- Conditions
- Advanced Malignant Solid Neoplasm, Clinical Stage III Cutaneous Melanoma AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8, Fallopian Tube Carcinoma
- Trial name
- NCT02419495
- Testing
- Capecitabine, Carboplatin, Cyclophosphamide
- Where
- 5 sites in United States
- Volunteers
- 221 people
- Sponsor
- M.D. Anderson Cancer Center
Melanoma, Breast Carcinoma
A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors
This is a Phase 1, multiple dose, ascending dose escalation study to define a MTD/RD and regimen of XmAb20717, to describe safety and tolerability, to assess PK and immunogenicity, and to preliminarily assess anti-tumor activity…
- Conditions
- Melanoma, Breast Carcinoma, Hepatocellular Carcinoma, Urothelial Carcinoma
- Trial name
- DUET-2 (NCT03517488)
- Testing
- XmAb20717
- Where
- 17 sites in United States
- Volunteers
- 150 people
- Sponsor
- Xencor, Inc.
Neoplasms
First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors
This is a first time in-human (FTIH) study designed to investigate the safety, tolerability, pharmacokinetics (PK), and immunogenicity of remzistotug in participants with select loco-regionally recurrent solid tumors or…
- Trial name
- NCT05277051
- Testing
- Remzistotug, Dostarlimab, Belrestotug
- Where
- 26 sites in United States, Australia and 7 more
- Volunteers
- 152 people
- Sponsor
- GlaxoSmithKline
Head and Neck Cancer Squamous Cell Carcinoma, Non-small Cell Lung Cancer
Study of ADCT-301 in Patients With Selected Advanced Solid Tumors
This study evaluates ADCT-301 in patients with Selected Advanced Solid Tumors. Patients will participate in a Treatment Period with 3-week cycles and a Follow-up Period every 12 weeks for up to 1 year after treatment…
- Conditions
- Head and Neck Cancer Squamous Cell Carcinoma, Non-small Cell Lung Cancer, Gastric Cancer, Esophageal Cancer
- Trial name
- NCT03621982
- Testing
- ADCT-301, Pembrolizumab
- Where
- 9 sites in United States, Belgium and 1 more
- Volunteers
- 78 people
- Sponsor
- ADC Therapeutics S.A.
Heart Surgery, Chest Tube
Timing for Removal of Chest Tubes in Adult Cardiac Surgery
Rationale: Evidence regarding the timing of chest tube removal after cardiac surgery is sparse. The timing of chest tubes removal constitutes a balancing act between risk of retained blood syndrome, infection, patient discomfort…
- Conditions
- Heart Surgery, Chest Tube, Effusion Pleural, Pain, Postoperative
- Trial name
- NCT04487262
- Testing
- Cardiac surgery
- Where
- Denmark
- Volunteers
- 515 people
- Sponsor
- Aarhus University Hospital Skejby
Lung, Lung Adenocarcinoma
Reinforced and Non-Reinforced Staple Lines in Fissureless Lobectomy
Prolonged Air Leak (PAL) is a common and serious problem after lung surgery. It can lead to worse patient outcomes, longer hospital stays, and higher costs.
- Conditions
- Lung, Lung Adenocarcinoma, Lung Adenosquamous Carcinoma, Lung Cancer, Non-Small Cell
- Trial name
- NCT06602661
- Testing
- Fissureless Lobectomy with Reinforced Staple Lines, Fissureless Lobectomy with Non-Reinforced Staple Lines
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- Surrey Thoracic Surgery Group
Difficult Intubation
A Comparison of a Macintosh Laryngoscope and Endotracheal Tube Introducer in a Manikin
In this prospective, randomized, cross-over study, investigators aimed to compare the first pass successes of inexperienced doctors with Macintosh laryngoscopy and endotracheal tube introducer on a manikin with continuous chest…
- Trial name
- NCT03419507
- Testing
- Endotracheal tube introducer, Macintosh laryngoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Derince Training and Research Hospital
Lung Neoplasms, Pulmonary Surgical Procedures
Staple-line Reinforcement for Prevention of Pulmonary Air Leakage
The aim of this study is to compare the efficacy of FORESEAL with stapling alone or associated with tissue sealant or glue in terms of air leakage duration after lung resection for cancer.
- Conditions
- Lung Neoplasms, Pulmonary Surgical Procedures, Surgical Staplers, Tissue Adhesives
- Trial name
- SPIRAL (NCT00925444)
- Testing
- FOREseal, Stapling
- Where
- France
- Volunteers
- 380 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Intubation
Nonintubated Versus Intubated Anesthesia in Video-assisted Thoracic Surgery
The purpose of this study is to compare to the patients undergoing nonintubated general anesthesia with laryngeal mask and undergoing intubated general anesthesia with double-lumen endotracheal intubation in Video-assisted…
- Trial name
- NCT04253795
- Testing
- Laryngeal mask, double lumen tube
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Antalya Training and Research Hospital
Drainage
Improved Drainage Strategy for Patients With Lung Wedge Resection
This study evaluates the viability and safety of two-lumen catheterization versus complete omission of chest tube in patients with lung wedge resection.
- Trial name
- NCT04207671
- Testing
- Complete omission of chest tube, Improved drainage strategy
- Volunteers
- 600 people
- Sponsor
- Guangdong Provincial People's Hospital
Educational Assessment, Chest Tube Insertion
Validation of a New Assessment Tool for Chest Tube Insertion (ACTION) on Two Different Simulators
The aim of this study is to collect validity evidence for the ACTION-tool on two different simulators: a porcine rib model, and Thiel embalmed human cadavers. Validity evidence will be collected following Messick's framework.
- Conditions
- Educational Assessment, Chest Tube Insertion, Validity
- Trial name
- NCT05396768
- Testing
- Assessment using the ACTION-tool.
- Where
- Belgium
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University Ghent