Clinical trials: Cervix Neoplasm
Cervical Cancer, Radiotherapy
Chemoradiotherapy With or Without Metformin in Locally Advanced Cervical Cancer
This is a prospective, single-center, phase II, randomized, window-of-opportunity trial initiated by researchers. The research hypothesis is that metformin can improve the level of hypoxia in locally advanced cervical cancer and…
- Conditions
- Cervical Cancer, Radiotherapy, Metformin, Hypoxia
- Trial name
- NCT06353061
- Testing
- Metformin, Radiotherapy, Chemotherapy
- Where
- China
- Volunteers
- 51 people
- Sponsor
- Peking Union Medical College Hospital
Prostate Cancer, Cervix Cancer
Medico-economic Evaluation of IMRT by Hi Art, RapidArc, VMAT Therapy in Prostate, Cervix and Anal Canal Cancers
The aim of the study is a medico-economic evaluation to estimate a cost differential between three modalities of Intensity-Modulated Radiation Therapy for cancers of the prostate, cervix and anal canal with pelvic lymph node…
- Conditions
- Prostate Cancer, Cervix Cancer, Anal Canal Cancers
- Trial name
- RCMI-PELVIS (NCT01325961)
- Testing
- IMRT using Rapid Arc - prostate cancer, IMRT using Rapid Arc - Anal canal cancer, IMRT using Rapid Arc - Cervix cancer
- Where
- 15 sites in France
- Volunteers
- 215 people
- Sponsor
- Institut Cancerologie de l'Ouest
Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma
MRI and PET Imaging in Predicting Treatment Response in Patients With Stage IB-IVA Cervical Cancer
This trial studies magnetic resonance imaging (MRI) and positron emission tomography (PET) imaging in predictive treatment response in patients with stage IB-IVA cervical cancer.
- Conditions
- Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Cervical Squamous Cell Carcinoma, Not Otherwise Specified, Cervical Undifferentiated Carcinoma
- Trial name
- NCT01992861
- Testing
- Computed Tomography, Diffusion Weighted Imaging, Dynamic Contrast-Enhanced Magnetic Resonance Imaging
- Where
- 6 sites in United States, Canada and 1 more
- Volunteers
- 51 people
- Sponsor
- University of Washington
Cervical Cancer
Contribution of PET/MRI in Locally Advanced Cervical Cancer (ATICC)
[18 F]fluorodeoxyglucose (18F-FDG) positron emission tomography-magnetic resonance imaging (PET/MRI) is a new hybrid imaging tool that has recently arrived in oncology, and is particularly promising.
- Trial name
- ATICC (NCT06083103)
- Testing
- 18-FDG PET-MRI
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Paul Strauss
Cervical Cancer ≥ FIGO IIB and or Lymph Node Metastases
Chemo-radio-immunotherapy With Nivolumab and Ipilimumab Treatment in Locally Advanced Cervical Cancer Patients
The purpose of this study is to use Chemo-radio-immunotherapy and maintenance therapy with Nivolumab and Ipilimumab in order to achieve improved outcome in patients with locally advanced cervical cancer.
- Trial name
- CERAD-IMMUNE (NCT05504642)
- Testing
- Pre-Chemo-radio-immunotherapy Treatment (Nivolumab/Ipilimumab), Concurrent Chemo-radio-immunotherapy (Nivolumab/Ipilimumab), Maintenance Treatment (Nivolumab/Ipilimumab)
- Sponsor
- Universitätsklinikum Köln
Cervical Intraepithelial Neoplasia, Cervical Cancer (Early Detection)
Cervical Intraepithelial Neoplasia Screening Using Liquid-Based Pap Smear Among Egyptian Women
This observational study aims to screen Egyptian women aged 25-60 for cervical intraepithelial neoplasia (CIN) using liquid-based Pap smear during routine gynecological visits at Kasr Al-Aini outpatient clinics.
- Trial name
- NCT07250841
- Testing
- Liquid-Based Pap Smear (LBC)
- Where
- Egypt
- Volunteers
- 984 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Human Papillomavirus Vaccination, Cervical Cancer Prevention
Integrating HPV Education Into School Health Programs in Cambodia and Kenya
The Clinton Health Access Initiative conducted a mixed-methods, school-based interventional study in Cambodia and Kenya to evaluate whether integrating age-appropriate human papillomavirus (HPV) education into existing school…
- Trial name
- NCT07784283
- Testing
- Integrated HPV Education
- Where
- 5 sites in Cambodia, Kenya
- Volunteers
- 9,054 people, healthy volunteers welcome
- Sponsor
- Clinton Health Access Initiative Inc.
Cervical Cancer Screening
St. Joe's Invitation Effectiveness Study
The objective of this study is to evaluate the effectiveness of offering self-sampling for high risk human papilloma virus (HPV) testing in order to increase the number of women who are screened for cervical cancer.
- Trial name
- NCT04658888
- Testing
- Evalyn Self-Sampling Brush
- Where
- United States
- Volunteers
- 964 people
- Sponsor
- Milton S. Hershey Medical Center
Cardio-vascular Disease, Stroke Cancer
Improving Access to Control of Diseases for Women
The aim of this study is to evaluate the feasibility and acceptability of the model of delivering CHW-driven home-based comprehensive NCD control services aimed to prevent premature deaths from cardio-vascular diseases, stroke…
- Conditions
- Cardio-vascular Disease, Stroke Cancer, Breast Cancer, Oral Cancer
- Trial name
- IMPACD (NCT03604939)
- Testing
- Evaluation of social, cultural and behavioral factors, Evaluation of the feasibility and acceptability of delivery of early detections services
- Where
- India
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- International Agency for Research on Cancer
Cervical Cancer Screening, Cervical Cancer
Evaluation of Three Strategies Based on Vaginal Self-sampling Kit Send to Home of Unscreened Women for Cervical Cancer
Despite the existence of an effective screening test (pap smear), cervical cancer is, every year in France, the cause of more than 3,000 new cases and 1,100 deaths.
- Trial name
- APACHE-4 (NCT03856684)
- Testing
- Self-sampling kit sent at home, Self-sampling kit sent at home + SMS reminder, Letter offering a self-sampling kit "on request"+ SMS reminder
- Where
- France
- Volunteers
- 10,400 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Advanced Solid Tumours, Squamous Cell Carcinoma of Head and Neck
A Phase I/II Trial of UCB4594 in Participants With Advanced Cancer
This clinical trial is looking at UCB4594. This is the first time the drug is being tested in humans. UCB4594 is a type of drug called a monoclonal antibody.
- Conditions
- Advanced Solid Tumours, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms
- Trial name
- NCT06380816
- Testing
- UCB4594
- Where
- 4 sites in United Kingdom
- Volunteers
- 167 people
- Sponsor
- Cancer Research UK
Head and Neck Cancer, Lung Cancer
Study of [F 18]HX4 Positron Emission Tomography (PET) as a Tool to Detect Hypoxia in Tumors
This pilot phase II study is designed as a test and retest study to investigate [F 18]HX4 as a reliable non-invasive PET imaging marker for detection of tumor hypoxia regions and to establish a threshold for [F 18]HX4 uptake in…
- Conditions
- Head and Neck Cancer, Lung Cancer, Liver Cancer, Rectal Cancer
- Trial name
- HX4-200 (NCT01075399)
- Testing
- [F 18]HX4
- Volunteers
- 50 people
- Sponsor
- Siemens Molecular Imaging
Cervical Cancer
Use of Social Networking to Survey Women With Small and Large Cell Carcinomas of the Cervix
Objectives: Primary: 1. To assess the feasibility of using social networking groups to survey patients with rare cancers. Secondary:1.
- Trial name
- NCT01606293
- Testing
- Questionnaires
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- M.D. Anderson Cancer Center
Head and Neck Cancer, Gynecologic Cancer
Quality of Life Assessment of Radiotherapy in Recurrent Head and Neck Cancer
The purpose of this study is to examine the uses of a mobile health-based assessment and symptom monitoring platform.
- Conditions
- Head and Neck Cancer, Gynecologic Cancer, Cervical Cancer, Endometrial Cancer
- Trial name
- NCT05850663
- Testing
- Ecologic Momentary Assessment (EMA)
- Sponsor
- University of Oklahoma
Advanced Cervical Cancer
Combination Therapy for First Line Treatment of Advanced Cervical Cancer
This is a single center phase 1 trail to observe safety and efficacy of Paclitaxel plus Cisplatin\Carboplatin, PD-L1 antibody Toripalimab and Anlotinib as first-line regimen to treat the patient with metastatic 、persistent or…
- Trial name
- NCT04731038
- Testing
- Anlotinib, Toripalimab, Paclitaxel, Cisplatin/ Carboplatin
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Ruijin Hospital
Cervical Cancer
To Evaluate the Efficacy and Safety of PEG-rhG-CSF（Jinyouli®） in Reducing Neutropenia in Patients With Cervical Cancer
A Prospective, open, randomized, controlled clinical study to evaluate the efficacy and safety of PEG-rhG-CSF(PEGylated recombinant human granulocyte stimulating factor injection) in reducing neutropenia during…
- Trial name
- NCT03206684
- Testing
- PEG-rhG-CSF, rhG-CSF
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Air Force Military Medical University, China
Cervical Cancer
Thunderbeat Technology vs Standard Bipolar Electro Surgery in Laparoscopic Radical Hysterectomy and Pelvic Lymphadenectomy for Cervical Cancer
This prospective randomized pilot study is aimed to verify if the operative time of a LRH with pelvic lymphadenectomy for early stage cervical cancer (FIGO stages IA2-IB1-IIA<2cm) and for advanced stage cervical cancer (FIGO…
- Trial name
- Thunder Cervix (NCT01717781)
- Testing
- Thunderbeat technology, Standard bipolar electrosurgery
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Catholic University of the Sacred Heart
Uterine Cervical Neoplasms, Sexually Transmitted Diseases
Preventive Sexual Health Screening Among Female-to-Male (FTM) Transgender Adult Patients
The purpose of this study is to assess the acceptability and effectiveness of utilizing vaginal self-swabs for HPV DNA testing as compared to provider-collected cervical swabs for HPV, as well as to investigate the prevalence of…
- Trial name
- NCT02401867
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Fenway Community Health
Cervical Cancer Screening, HPV
Cervical Thermal Ablation to Treat Persistent HPV Infection
Thermal ablation of women ≥40 years of age with persistent Human papillomavirus (HPV) infection. A pilot and intervention study.
- Conditions
- Cervical Cancer Screening, HPV, Thermal Ablation
- Trial name
- NCT07376031
- Testing
- Treatment
- Where
- Denmark
- Volunteers
- 131 people
- Sponsor
- Hvidovre University Hospital
Cervix Neoplasms, Uterine Neoplasms
Magnetic Resonance Imaging Guided Gynecologic Brachytherapy
The primary goal of this pilot study is to assess the feasibility of using magnetic resonance (MR) imaging guidance in the Magnetic Resonance Therapy (MRT) unit at the Brigham and Women's Hospital during the implantation of…
- Conditions
- Cervix Neoplasms, Uterine Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms
- Trial name
- NCT00112307
- Testing
- Brachytherapy
- Volunteers
- 15 people
- Sponsor
- Brigham and Women's Hospital