Clinical trials: Cervical Stenosis
Radiculopathy
Cervical Foraminal Stenosis and Radiculopathy - ACDF Versus Minimal Invasive Posterior Cervical Foraminotomy.
A prospective randomized clinical trial. Cervical spondylotic foraminal stenosis with radiculopahty. Comparison results between 2 treatment options: ACDF and minimal invasive posterior cervical foraminiotomy.
- Trial name
- NCT02350621
- Testing
- ACDF, minimal invasive Posterior Cervical Foraminotomy
- Volunteers
- 80 people
- Sponsor
- Stockholm Spine Center AB
Spinal Cord Injuries, Neurogenic Bladder Dysfunction
Functional and Structural Changes in the Central Nervous System Following Spinal Cord Injury
Building on recent improvements, state-of-the-art functional MRI will be applied as an advanced diagnostic tool for the lumbosacral cord in spinal cord injury (SCI) patients to characterize the remaining neuronal activity of the…
- Conditions
- Spinal Cord Injuries, Neurogenic Bladder Dysfunction, Degenerative Cervical Spinal Stenosis
- Trial name
- NCT05681936
- Where
- Switzerland
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Cervical Spinal Stenosis, Thoracic Spinal Stenosis
The Effect of Oxytocin Nasal Spray on Preventing Postoperative Delirium in Elderly Patients Undergoing Orthopedic Surgery
Postoperative delirium is a delirium that occurs within 7 days after surgery or before hospital discharge. It has been shown that combined POD can increase the incidence of postoperative pulmonary infections, deep vein thrombosis…
- Conditions
- Cervical Spinal Stenosis, Thoracic Spinal Stenosis, Lumbar Spinal Stenosis, Rotator Cuff Injury
- Trial name
- NCT06945926
- Testing
- oxytocin nasal spray
- Where
- China
- Volunteers
- 227 people
- Sponsor
- Zhejiang University
Solid Malignancy Located in the Head and Neck, Cancer
Study of 68GaNOTA-Anti-MMR-VHH2 in Oncological Lesions, Cardiovascular Atherosclerosis, Syndrome With Abnormal Immune Activation and sarcoïdosis
Phase II study to evaluate the clinical potential of 68GaNOTA-anti-MMR-VHH2 for in vivo imaging of Macrophage Mannose Receptor (MMR)-expressing Macrophages by means of Positron Emission Tomography (PET) in patients with…
- Conditions
- Solid Malignancy Located in the Head and Neck, Cancer, Carotid Stenosis, Atherosclerosis of Artery
- Trial name
- MITRAS (NCT04758650)
- Testing
- 68GaNOTA-Anti-MMR-VHH2
- Where
- Belgium
- Volunteers
- 29 people
- Sponsor
- Universitair Ziekenhuis Brussel
Carotid Artery Stenosis
Ultrasound-guided Intermediate Cervical Plexus Block for Carotid Surgery
Since stroke and myocardial ischemia are major causes of perioperative morbidity and mortality associated with carotid endarterectomy, monitoring the brain and ensuring the best hemodynamic stability are important goals of…
- Trial name
- NCT02450734
- Testing
- Ultrasound-guided intermediate cervical plexus block
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Institut Mutualiste Montsouris
Low Back Pain, Neck Pain
The Effect of Integrated CAM Treatment in Hospitalized Patients
This study investigates the effect of hospital-based intensive non-surgical treatment in musculoskeletal patients admitted to an integrated hospital that offers both complementary and alternative medicine (CAM) and conventional…
- Conditions
- Low Back Pain, Neck Pain, Knee Pain, Shoulder Pain
- Trial name
- NCT02257723
- Testing
- Herbal medicine, Acupuncture, Pharmacopuncture
- Where
- South Korea
- Volunteers
- 100,000 people
- Sponsor
- Jaseng Hospital of Korean Medicine
Endometrial Cancer, Cervical Cancer
An Enhanced Vaginal Dilator to Reduce Radiation-Induced Vaginal Stenosis
This is a randomized control trial aimed to decreased radiation-induced vaginal stenosis in patients with endometrial or cervical cancer treated with post-operative external beam radiation therapy with or without brachytherapy.
- Conditions
- Endometrial Cancer, Cervical Cancer, Vaginal Stricture, Radiation Toxicity
- Trial name
- NCT03876860
- Testing
- Silicone Dilator, Standard Dilator
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Margaret Liotta
Barrett Esophagus, Esophageal Dysplasia
trūFreeze® Spray Cryotherapy Patient Registry
To collect efficacy and outcomes data related to the use of trūFreeze® spray cryotherapy for the treatment of unwanted tissue in the pulmonary and gastrointestinal settings.
- Conditions
- Barrett Esophagus, Esophageal Dysplasia, Esophageal Neoplasm, Esophageal Stenosis
- Trial name
- NCT01802203
- Testing
- truFreeze Spray Cryotherapy
- Where
- 16 sites in United States
- Volunteers
- 275 people
- Sponsor
- US Endoscopy Group Inc.
Cervical Stenosis
Use of Misoprostol in Case of Insertion Failure of Intrauterine Contraceptives
To assess the usefulnes sof misoprostol versus placebo (in a double-blind placebo controlled randomized clinical trial)to facilitate the insertion of copper-IUD and the levonorgestrel-releasing intrauterine system (LNG-IUS) in…
- Trial name
- NCT01754649
- Testing
- Misoprostol
- Where
- 2 sites in Brazil
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Luis Bahamondes
Analgesia, Epidural
Correlation of Intravascular Injection Rate and Severity of Cervical Neural Foraminal Stenosis
This study evaluates whether there is a correlation between intravascular injection rate and severity of cervical foraminal stenosis during cervical transforaminal epidural steroid injection
- Trial name
- NCT04071483
- Testing
- Cervical transforaminal epidural steroid injection
- Where
- South Korea
- Volunteers
- 126 people
- Sponsor
- Kyungpook National University Hospital
Cervical Foraminal Stenosis, Cervical Disc Herniation
Safety and Efficacy of Electromagnetic Navigation System Assisted Percutaneous Endoscopic Lumbar Decompression
There is a shallow learning curve with TELD (transforaminal endoscopic lumbar discectomy). The aim of this study is to assess the safety and efficacy of TELD assisted by electromagnetic navigation for treating lumbar disc…
- Trial name
- NCT05270486
- Testing
- Electromagnetic navigation system
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Régional de la Citadelle
Degenerative Cervical Kyphosis With Stenosis
Anterior Spinal Canal Reconstruction and Fusion Surgery for Treating Degenerative Cervical Kyphosis With Stenosis
Degenerative cervical kyphosis with stenosis (DCKS) is a common cervical spine degenerative disease, causing pain, numbness, and weakness of limbs, which seriously affect the quality of life of the patient.
- Trial name
- NCT04806360
- Testing
- ACRF surgery, conventional anterior surgery, conventional posterior surgery
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shanghai Changzheng Hospital
Acute Traumatic Cervical Central Cord Syndrom Injury
Prospective Study for Delay in Surgical Treatment of Traumatic Cervical Central Cord Injury in Canal Stenosis
The studied pathology concerns post traumatic cervical spinal cord contusion on narrow spinal canal. The pathophysiology remains controversial. This pathology does not enjoy consensus support.
- Trial name
- DS3CS (NCT02673320)
- Testing
- Early surgery within 48 hours, Delayed surgery at 15 days
- Where
- 5 sites in France
- Volunteers
- 72 people
- Sponsor
- Nantes University Hospital
Neck Pain, Radiculopathy, Cervical
Repeated Transforaminal Anesthetic Injections With or Without Glucocorticoid in Patients With Cervical Radiculopathy
The main objective is to evaluate pain and muscle strength in the upper extremities after treatment with cervical transforaminal injection of glucocorticoid vs.
- Conditions
- Neck Pain, Radiculopathy, Cervical, Cervical Foraminal Stenosis, Cervical Disc Disease
- Trial name
- NCT03541681
- Testing
- Glucocorticoid Injections, Anesthetic Injections
- Sponsor
- Region Skane
Adult Spinal Deformity, Degenerative Scoliosis
Gait and Paraspinal sEMG in Degenerative Spinal Diseases
This cross-sectional observational study aims to quantitatively compare three-dimensional gait parameters, surface electromyography (EMG) patterns, and radiological parameters among patients with different degenerative spinal…
- Conditions
- Adult Spinal Deformity, Degenerative Scoliosis, Sagittal Deformity, Sagittal Imbalance
- Trial name
- TDGKSEPDSD (NCT07309926)
- Testing
- Gait analysis and surface electromyography analysis
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Radiculopathy, Cervical Region
Predictors of Treatment Response to Stellate Ganglion Block in Cervical Radicular Pain
Purpose: Stellate ganglion block (SGB) is a procedure that uses ultrasound to guide a needle near a group of nerves in the neck called the stellate ganglion. A local anesthetic is then injected to block pain signals.
- Trial name
- NCT07476235
- Testing
- Cervical multifidus fatty degeneration, Primary etiology of foraminal stenosis, Steroid use during stellate ganglion block
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Asan Medical Center
Cervical Artery Stenosis, Intracranial Artery Stenosis
A Prospective Cohort of Patients With Cervical/Intracranial Arteries Stenosis in China
The aim of this study is to establish a prospective cohort of patients with cervical/intracranial arteries stenosis in China.
- Trial name
- NCT06595342
- Testing
- No intervention
- Where
- China
- Volunteers
- 60,000 people
- Sponsor
- The First Hospital of Jilin University
Lumbar Disk Herniation, Lumbar Spinal Stenosis
Screening and Prospective Cohort Study of Risk Factors for Enhanced Recovery After Spinal Fusion Surgery in Advanced Age Patient
To determine the high risk factors affecting accelerated recovery after spinal fusion surgery in advanced age patient.
- Conditions
- Lumbar Disk Herniation, Lumbar Spinal Stenosis, Lumbar Spondylolisthesis, Cervical Spondylotic Myelopathy
- Trial name
- NCT06591442
- Testing
- This is an observational study
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Esophageal Cancer
Balloon Dilation to Permit Complete Endoscopic Ultrasound Staging in Esophageal Cancer
Despite improvement in treatment-related morbidity and mortality, esophageal cancer is still one of the most lethal malignancies. Accurate staging is essential to establish prognosis and for patient management.
- Trial name
- CT0046 (NCT01950442)
- Testing
- Balloon dilation
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Degenerative Spine, Degeneration of Lumbar Intervertebral Disc
Percutaneous Trans-facet Spine Fixation
Percutaneous Trans-facet Fixation Massoud-Goel Technique and Theory for Treatment of Degenerative Spine
- Conditions
- Degenerative Spine, Degeneration of Lumbar Intervertebral Disc, Degenerative Cervical Disc Disease, Ligamentum Flavum Hypertrophy
- Trial name
- Massoud-Goel (NCT07001969)
- Testing
- Massoud-Goel Technique and Theory, Percutaneous Trans-facet Fixation for Treatment of Degenerative Spine
- Where
- Egypt
- Volunteers
- 77 people
- Sponsor
- Mahmoud Massoud