Clinical trials: Cervical Preparation
Thyroid Cancer
CASE 1320: RAI Uptake and Serum Prolactin in Thyroid Cancer
Radioactive iodine (RAI) is a radioisotope used to ablate thyroid gland remnant after thyroidectomy in patients diagnosed with differentiated thyroid carcinoma (DTC).
- Trial name
- NCT04495985
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- The Cleveland Clinic
Uterine Polyp, Uterine Bleeding
Pharmacological Preparation of the Cervix for Hysteroscopy
Pain accompanying office hysteroscopy is the most common reason for its discontinuation. Urogenital atrophy may cause technical difficulties in passage through the cervical canal, further increasing the pain.
- Conditions
- Uterine Polyp, Uterine Bleeding, Endometrium; Senility
- Trial name
- NCT05783479
- Testing
- estradiol, Hyaluronic acid
- Where
- Poland
- Volunteers
- 96 people
- Sponsor
- Jagiellonian University
Abortion, Induced
Cervical Preparation Before Dilation and Evacuation
The purpose of this research study is to compare three different ways of opening a woman's cervix before her second-trimester surgical abortion.
- Trial name
- NCT01751087
- Testing
- Mifepristone, misoprostol, Osmotic dilators
- Where
- 7 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood League of Massachusetts
Pain
12 Versus 20 mL PCB for D&E Cervical Prep
More research is needed to investigate methods of pain control for cervical preparation for abortion procedures. Women report pain with paracervical block injection as well as with osmotic dilator placement.
- Trial name
- NCT03356145
- Testing
- 12 mL paracervical block, 20 mL paracervical block
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Stanford University
Legally Induced Abortion Without Mention of Complication
Pre-Operative Effects of Mifepristone on Dilation and Evacuation Services
This research study investigates the use of a drug, mifepristone, given before second trimester abortion. Mifepristone is a medication that is approved for medical abortion during the first trimester.
- Trial name
- POEM (NCT01862991)
- Testing
- Hygroscopic cervical dilators, Misoprostol, Intra-amniotic digoxin
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Stanford University
Induced Abortion
Same-Day Mifepristone-Misoprostol Compared to Misoprostol Only for Surgical Abortion Cervical Preparation
A randomized double---blinded comparison of same---day mifepristone and misoprostol with misoprostol only for cervical preparation in second---trimester surgical abortion in 100 women at 14 0/7---19 6/7 weeks gestation.
- Trial name
- MMSAP (NCT02412618)
- Testing
- Mifepristone, Misoprostol
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Surgical Abortion
Cervical Preparation of Abortions Under Paracervical Block in the First Trimester:
Surgical abortion is one of the most frequently surgery of women in the world. 43 millions are annually performed in the world. 90% of the abortions are performed during the first trimester of pregnancy before 13 weeks.
- Trial name
- BPCEN (NCT03043014)
- Testing
- Mifépristone versus Misoprostol
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Second Trimester Abortion
Cervical Preparation With Mifepristone Prior to Osmotic Dilators
The investigators plan to study the role of mifepristone prior to the placement of cervical osmotic dilators to evaluate if the medication helps increase the number of dilators.
- Trial name
- NCT03714880
- Testing
- Mifepristone 200 MG
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
HPV, HPV-Related Cervical Carcinoma
STI Knowledge and HPV Vaccine Acceptance in Bamako, Mali in 2012
Although screening for pre-cancerous cervical lesions and human papilloma virus (HPV) vaccination are accepted and effective means to prevent cervical cancer, women in Mali have limited access to these interventions.
- Trial name
- NCT05767138
- Testing
- HPV Vaccine Acceptance Survey
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Global Alliance to Immunize Against AIDS Vaccine Foundation
Cervical Preparation
Mifepristone vs Misoprostol
The Investigator team hypothesizes that in a randomized trial comparing mifepristone-alone or misoprostol-alone for cervical preparation for procedural abortions at 12 to 16 weeks in hospital-based care, the proportion of…
- Trial name
- NCT06502158
- Testing
- Mifepristone, Misoprostol
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Surgical Abortion
Cervical Preparation for Surgical Abortion at 12-14 Weeks: a Prospective, Randomized, Evaluator-blinded, Multicenter, Controlled Comparison Between Mifepristone, Misoprostol and Their Combination
More than 100 000 surgical abortions are annually performed in France. About four in ten women will have an abortion in their life.
- Trial name
- NCT01795599
- Testing
- Mifegyne ®, Gymiso®
- Where
- France
- Volunteers
- 198 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Contraception
Use of Misoprostol for Intrauterine Device (IUD) Insertion in Nulliparous Women
The purpose of this study is to evaluate if the use of misoprostol can make it easier for a provider, and less painful for a woman, to place an IUD if she has never had a child before.
- Trial name
- NCT01001897
- Testing
- Misoprostol
- Where
- 2 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Thyroid Cancer
Evaluation Study of L-T3 Utility in the Follow-up of Patients With Thyroid Cancer
To compare the hypothyroid state in patients with thyroid cancer prepared either by placebo or L-T3 following L-T4 withdrawal in preparation for whole body scintigraphy.
- Trial name
- NCT00223158
- Testing
- Liothyronine
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Patrice Perron
Abortion, Induced
Value of Mifepristone in Cervical Preparation Prior to Dilation and Evacuation 19-24 Weeks
A common practice for preparation for surgical abortion after 19 weeks gestation is the placement of multiple sets of osmostic dilators 1-2 days prior to the procedure.
- Trial name
- NCT01615731
- Testing
- Mifepristone, Hygroscopic cervical dilators, Misoprostol
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Stanford University
Second Trimester Abortion
Laminaria Compared to Dilapan-S for Cervical Preparation Before Dilation and Evacuation at 18-24 Weeks of Gestation
Primary objective: To study the difference in dilation and evacuation (D\&E) procedure time following overnight cervical preparation with laminaria or Dilapan-S™.
- Trial name
- NCT02033083
- Testing
- Laminaria, Dilapan-S
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood of Greater New York
Evening Primorose Oil, Misoprostol
Evening Primorose Oil Versus Misoprostol in Cervical Preparation Before Operative Hysteroscopy
This study aimed to compare the efficacy of misoprostol versus intravaginal Evening Primrose Oil capsule as a cervical ripening agent prior to operative hysteroscopy.
- Conditions
- Evening Primorose Oil, Misoprostol, Cervical Preparation, Hysteroscopy
- Trial name
- NCT07641595
- Testing
- Primorose Oil, Misoprostol
- Where
- Egypt
- Volunteers
- 230 people
- Sponsor
- Sohag University
Head and Neck Neoplasms
S-Frame CT Immobilization Masks For Patients Undergoing Radiation Therapy For Head and Neck Cancer
Immobilization devices such as thermoplastic masks are used routinely in the radiation treatment of head and neck cancer patients.
- Trial name
- NCT00252473
- Testing
- MedTec S-frame Immobilization Masks
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University Health Network, Toronto
Head and Neck Cancer
Adherence to Swallowing Exercises in Head and Neck Cancer
The goal of this research study is to help patients complete the swallowing and dental care exercises they are supposed to perform during radiation treatment.
- Trial name
- NCT00761397
- Testing
- Interview, Phone Call, Brochure
- Where
- United States
- Volunteers
- 485 people
- Sponsor
- M.D. Anderson Cancer Center
Abortion, Second Trimester, Abortion, Medical
Foley Balloon for Cervical Preparation Before Dilation and Evacuation
To evaluate the Foley Balloon technique for cervical preparation before second trimester surgical abortion between 16 and 21 weeks estimated gestational age in combination with misoprostol to prepare the cervix before dilation…
- Trial name
- NCT06850974
- Testing
- Foley Balloon Catheter, Misoprostol, Laminaria
- Where
- Mozambique
- Volunteers
- 102 people
- Sponsor
- Stony Brook University
Esophageal Cancer
Mechanical Bowel Preparation Versus no Bowel Preparation for Esophageal Cancer Surgery
The study type was designed as a prospective multicenter randomized controlled study. The patients will be divided into intervention group and control group, 281 patients were needed for each group and 562 patients would be…
- Trial name
- NCT05523960
- Testing
- No MBP
- Where
- China
- Volunteers
- 652 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences