Clinical trials: Cerebral Oxygen Saturation
Pulmonary Surgical Procedures, Recovery Period
Oxygen Peripheral Saturations and Lung Surgery
The purpose of this study is to compare the ability of two peripheral and non invasive devices to detect hypoxic events during one-lung ventilation and during the early postoperative period.
- Trial name
- NCT01255033
- Testing
- Monitoring of tissular oxygenation
- Where
- France
- Volunteers
- 47 people
- Sponsor
- Hopital Foch
Aortic Stenosis Disease, TAVI(Transcatheter Aortic Valve Implantation)
Cerebral Regional Oxygen Saturation During TAVI - The CROS-TAVI Prospective Registry
This single-center, non-commercial clinical study investigates how different types of transcatheter aortic valve prostheses affect cerebral oxygen saturation during the procedure (TAVI - Transcatheter Aortic Valve Implantation).
- Conditions
- Aortic Stenosis Disease, TAVI(Transcatheter Aortic Valve Implantation), Cerebral Oxygen Saturation, Hemodynamic Changes
- Trial name
- CROS-TAVI (NCT07016789)
- Testing
- Near-infrared spectroscopy monitoring (NIRS) INVOS 5100C
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Intracranial Pressure Increase
Comparison of ONSD and rSO2 Measurements Between General and Spinal Anesthesia in C-Section
General anesthesia and regional anesthesia can be chosen in cesarean operations. Endotracheal intubation and mechanical ventilation are components of general anesthesia.
- Trial name
- NCT04446013
- Testing
- Optic Nerve Sheath Diameter Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Neonatal Cerebral Oxygenation, Cesarean Section
Effects of Spinal Versus General Anesthesia on Neonatal Cerebral Oxygenation During Cesarean Section
This prospective observational study evaluates and compares the effects of spinal and general anesthesia techniques used during elective cesarean section on neonatal cerebral regional oxygen saturation (crSO₂) during the early…
- Trial name
- NEO-OXY-CS (NCT07477093)
- Testing
- No intervention (observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Akdeniz University Hospital
Cataract Extraction, Anesthesia, Local
Cerebral Oxymeter and End Tidal Carbondioxide Values Under Surgical Drapes With and Without Past COVID-19 Infection
Today, phacoemulsification has become the most commonly applied method in the treatment of cataract, which is considered as a public health problem.
- Conditions
- Cataract Extraction, Anesthesia, Local, Optic Nerve Sheath
- Trial name
- NCT05571683
- Testing
- oxygen support
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Duzce University
Coronary Artery Bypass Graft
High Frequency Ventilation During Off Pump Coronary Artery Bypass Graft (CABG)
This study is to test the safety of high frequency-low volume ventilation during off pump coronary artery bypass as reflected in the near infrared spectroscopy values for cerebral oxygenation.
- Trial name
- VHF (NCT00863044)
- Testing
- Apnea, High frequency ventilation
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Montreal Heart Institute
Perfusion Index and Cerebral NIRS Trends in Low Cardiac Output Syndrome
Can Perfusion Index and Cerebral Oxygen Saturation Trends Predict Low Cardiac Output in Pediatric Cardiovascular Surgeries
In this prospective, observational study, we aim to investigate whether routinely monitored Perfusion Index (PI) and cerebral oxygen saturation (NIRS) values in pediatric patients aged 0-6 undergoing congenital heart surgery are…
- Trial name
- NCT06759506
- Volunteers
- 40 people
- Sponsor
- Bozyaka Training and Research Hospital
Cerebral Oxygen Saturation
Influence of Variations in Systemic Blood Flow and Blood Pressure on Cerebral Oxygenation Measured by Cerebral Oximetry
This study emphasizes on the influence of changes in systemic flow and systemic mean arterial blood pressure (MAP) during cardiopulmonary bypass (CPB) on cerebral oxygenation assessed by near-infrared spectroscopy (NIRS).
- Trial name
- NCT01424800
- Testing
- A disposable NIRS (near-infrared spectroscopy) sensor will be applied on the patient's forehead for continuous registration of the cerebral oxygen saturation.
- Where
- Belgium
- Volunteers
- 34 people
- Sponsor
- University Hospital, Ghent
Epilepsy
Pre-oxygenation and Measures of Gas Exchanges During Seizures in the Epilepsy Monitoring Unit
The primary goal of the study is to assess the effect of pre-oxygenation on oxygen and carbon dioxide levels during seizures in patients admitted at the Epilepsy Monitoring Unit (EMU).
- Trial name
- NCT02241798
- Testing
- oxygen
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- NYU Langone Health
Delirium, Dementia, Amnestic, Cognitive Disorders, Arthroplasty, Hip Replacement
Cerebral Regional Oxygen Saturation and Markers of Brain Damage During Primary Hip Arthroplasty
Postoperative Cognitive Disorders (POCD) are common in hospitalized people > 60 year old, especially in orthopedic patients. Etiology of POCD is complex, and in some aspects still remains unclear.
- Trial name
- NCT02342236
- Testing
- cemented or cementless type of hip prothesis
- Where
- Poland
- Volunteers
- 18 people
- Sponsor
- Military Institute od Medicine National Research Institute
Hypoplastic Left Heart, Surgery
NIRS in Neonatal Cardiac Surgery
Due to the small size of infants and the use of bypass machines, physicians have difficulty assessing whether the infant's brain and body is getting enough oxygen during heart surgery.
- Trial name
- NCT00166101
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Emory University
Epilepsies, Partial
Cerebral Oxygen Saturation and Cytochrome Oxidase REDOX State in Children With Epilepsy: A Pilot Study
The purpose of this pilot study is to describe the relationship of regional cerebral oximetry and cytoximetry, measured using near-infrared spectroscopy, with seizure activity in the periictal period in children with epilepsy.
- Trial name
- NCT03054961
- Testing
- Near-infrared spectroscopy
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Medical College of Wisconsin
Hypotension During Surgery, Hemodynamic Instability
Prevention or Treatment of Arterial Hypotension and Oxygen Cerebral Saturation During Major Abdominal Surgery
In this study investigators will explore the association between intraoperative arterial hypotension and cerebral oxygen saturation in patients scheduled for major abdominal surgery.
- Trial name
- NCT05481047
- Testing
- HPI
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Establish the Incidence Rate of Abdominal and Cerebral Hyperoxemia and Hypoxemia Events in Neonates at Birth
Monitoring of Cerebral and Abdominal Tissue Oxygen Saturation in Neonates
Near-infrared spectroscopy (NIRS) functions in a manner similar to pulse oximetry, using the difference in absorptive qualities of oxy- and deoxyhemoglobin to infrared light to quantify the percent saturation.
- Trial name
- NCT03149731
- Testing
- NIRS
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xijing Hospital
Anxiety
Effect of Different Doses of Dexmedetomidine on Cerebral Oxygen Saturation and Postoperative Anxiety in Elderly Patients
To investigate the effect of different doses of dexmedetomidine on Cerebral Oxygen Saturation and Postoperative anxiety in elderly patients undergoing laparoscopic surgery
- Trial name
- NCT05640427
- Testing
- Dexmedetomidine, normal saline
- Where
- China
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Qinhuangdao
Oxygen Deficiency
Comparison of Oxygen Reserve Index and Regional Cerebral Oxygen Saturation Indetermining Hypoxia in Obese Patients
The primary aim of this study is to compare the effectiveness of ORI and rcSO2 in predicting hypoxia early in obese patients who are sensitive to hypoxia.
- Trial name
- NCT06404151
- Testing
- monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Depression
Hyperventilation Combined With Etomidate or Ketamine Anesthesia in ECT Treatment of Major Depression
This is a randomized controlled study assessing the effect of pre-emptive hyperventilation on ECT seizure duration, cerebral desaturation and remission of depressive symptoms in patients with Major Depressive Disorder.
- Trial name
- NCT02924090
- Testing
- Etomidate, Ketamine, Hyperventilation
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University of Manitoba
Cerebral Ischemia
Correlation of Cerebral Oxygen Saturation Measured From 2 Sensor Sites: Forehead vs. Temporal
Cardiac surgery and neurosurgery may decrease cerebral blood flow leading to cerebral dysfunction. Regional cerebral oxygen saturation (rScO2) monitor via Near-infrared spectometry (NIRS) is recommended for early detection and…
- Trial name
- NCT05087836
- Testing
- Sensor at forehead area, Sensor at temporal area
- Where
- Thailand
- Volunteers
- 21 people
- Sponsor
- Khon Kaen University
Brain Death
Organ Donor Tissue Oxygen Saturation as a Predictor of Number of Organs to Transplant Per Donor
The objective of this study is to quantify the association between tissue oxygen saturation (StO2) during the donor management phase of the Death by Neurological Criteria (DNC) organ donor and the number of organs transplanted…
- Trial name
- NCT01819116
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Cleveland Clinic
Anesthesia, Cerebral Blood Flow
Hypertension and Cerebrovascular Hemodynamics in General Anaesthesia
During anesthesia, blood pressure-raising medications are often required to achieve an adequate blood pressure level. However, there is limited knowledge about what constitutes an adequate blood pressure to ensure sufficient…
- Conditions
- Anesthesia, Cerebral Blood Flow, Regional Cerebral Oxygen Saturation, Blood Pressure
- Trial name
- NCT06855407
- Testing
- Blood pressure elevation
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Umeå University