Clinical trials: Cerebral Hemodynamic
Stroke, Acute
Hemodynamic Response and Motor Functions Following Transcranial Direct Current Stimulation in Acute Stroke
The aim of the present study is to evaluate the possible effect of using dual-tDCS applied before conventional physical therapy on motor functions and hemodynamic response
- Trial name
- NCT04051658
- Testing
- Transcranial direct current stimulation
- Where
- Thailand
- Volunteers
- 96 people
- Sponsor
- Mahidol University
Chronic Pain, Rheumatoid Arthritis
Effects of Virtual Reality on Brain Hemodynamic Activity in Chronic Pain
Virtual reality systems have been applied in recent years to reduce pain intensity and fear of movement in individuals with acute and chronic pain.
- Conditions
- Chronic Pain, Rheumatoid Arthritis, Virtual Reality
- Trial name
- NCT06154850
- Testing
- Immersive virtual reality, Non-immersive virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Acibadem University
Functional Magnetic Resonance Imaging
A Study of Two Methodologies for Measuring Blood Flow in the Brain in Response to Non-Drug Stimuli (P08085/MK-0000-180)
This study will identify a dose of ferumoxytol that can reliably detect changes in blood flow/volume in response to non-drug stimuli.
- Trial name
- NCT01244282
- Testing
- fMRI with sensory stimulation
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Mechanical Circulatory Support
BRAIN-HEART Ultrasound Study Normative Values for Transcranial Doppler Based Cerebral Blood Flow Assessment
There is a dire need to establish normative values for transcranial Doppler(TCD) derived cerebral blood flow parameters for each type of Mechanical circulatory support (MCS) device and explore the relationship between the MCS…
- Trial name
- MCS (NCT05924503)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Wake Forest University Health Sciences
Carotid Endarterectomy, Percutaneous Transluminal Angioplasty
Study of Blood Flow Changes and Microemboli During Carotid Surgery
The purpose of this study is to determine the clinical and radiologic implications of the intraoperative microemboli during carotid revascularization.
- Conditions
- Carotid Endarterectomy, Percutaneous Transluminal Angioplasty, Cognitive Aspects, Diffusion Weighted MRI
- Trial name
- NCT01343615
- Testing
- carotid stenting, carotid endarterectomy
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Campinas, Brazil
Cerebral Venous Thrombosis
Evaluation of Cerebral Oxygenation and Hemodynamics in Patients With Cerebral Venous Thrombosis
Cerebral hypoperfusion and hypoxia are the major determinants of neurological outcomes following acute brain injury as proved in Traumatic Brain Injury/Sub Arachnoid Haemhorrhage literature.
- Trial name
- NCT03033966
- Testing
- NIRS based Cerebral Oximetry
- Where
- India
- Volunteers
- 17 people
- Sponsor
- Dhritiman Chakrabarti
Treatment Resistant Schizophrenia
Comparison of Maintenance ECT Versus Clozapine in Treatment-resistant Schizophrenia
The proposed study will be conducted to compare the efficacy of maintenance ECT (M-ECT) vs Clozapine in treatment resistant schizophrenia (TRS) in terms of change in psychopathology measures and cerebral hemodynamics.
- Trial name
- NCT03807882
- Testing
- Bilateral M-ECT, Clozapine
- Where
- India
- Volunteers
- 60 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Healthy Participants
Prefrontal Hemodynamics and Working Memory After Exhaustive Aquatic Exercise
This study compared prefrontal cortex hemodynamics and working memory performance following exhaustive aquatic exercise between endurance athletes and physically active individuals.
- Trial name
- NCT07837661
- Testing
- Incremental Exhaustive Aquatic Stepping Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Traumatic Brain Injuries, Brain Injuries,Traumatic
Doppler Ultrasonography Parameters and Mortality in Traumatic Brain Injury
The purpose of this study is to find out whether blood flow measurements of the brain and neck arteries, obtained with bedside Doppler ultrasonography are associated with neurological outcome and survival in adult patients with…
- Trial name
- NCT07890259
- Testing
- Transcranial and Carotid Doppler Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Inonu University
Epilepsy
Electro- Hemodynamic Activity in Children: Combined Analysis by Video -EEG Spectroscopy and Near-infrared (NIRS )
Epilepsy in children is a major public health issue. It is the first neurological disease of the child.
- Trial name
- AEHCEE (NCT02826915)
- Testing
- Near Infra Red Spectroscopy (NIRS), Electroencephalogram (EEG)
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Brain Arteriovenous Malformation
Registry of Multimodality Treatment for Brain Arteriovenous Malformation in Mainland China
This study is a multi-center, prospective, registry study. This research was supported by the National Key Research and Development Program.
- Trial name
- MATCH (NCT04572568)
- Testing
- Multi-disciplinary assessment
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Beijing Tiantan Hospital
Orthostatic Hypotension, Pure Autonomic Failure
Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure
Compression garments have been shown to be effective in the treatment of orthostatic hypotension in autonomic failure patients. The purpose of this study is to determine the hemodynamic mechanisms by which abdominal compression…
- Conditions
- Orthostatic Hypotension, Pure Autonomic Failure, Multiple System Atrophy, Autonomic Failure
- Trial name
- NCT02429557
- Testing
- Abdominal compression, midodrine
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Vanderbilt University Medical Center
Alcohol Dependence
Cerebral Hemodynamics With rTMS in Alcohol Dependence
The present study measures the cerebral hemodynamic indices of alcohol dependent patients and observe the relative changes in these parameters with rTMS application.
- Trial name
- NCT02446067
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- India
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Central Institute of Psychiatry, Ranchi, India
Magnesium Sulfate, Remifentanil
Anesthesia Techniques, Neuroprotection and Surgical Field in FESS Under Controlled Hypotension
This prospective, randomized controlled trial investigates the effect of four different anesthetic maintenance techniques on surgical field conditions, hemodynamic stability, and neuroprotection during functional endoscopic sinus…
- Conditions
- Magnesium Sulfate, Remifentanil, S 100beta, S100 Beta Protein, Human
- Trial name
- NCT07181564
- Testing
- Propofol / Remifentanil, Ketamine + Magnesium sulfate (drug combination), Sevoflurane and Remifentanil
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- University General Hospital of Patras
Carotid Stenosis
Diabetes and Risk of Ischemic Stroke.
Diabetes in an independent risk factor for ischemic stroke, whose associated mortality rate is higher and sequelae more serious than for nondiabetics.
- Trial name
- NCT06401902
- Testing
- carotid clamping
- Where
- France
- Volunteers
- 3,739 people
- Sponsor
- Institut Mutualiste Montsouris
Trans Cranial Doppler Ultrasonography in Heamodynamic Optimisation in Septic Shock
Hemodynamic Optimisation Guided With Transcranial Doppler in Septic Shock
Randomized, controlled, prospective trial, including ICU patients with Sepsis or septic Shock, at the early phase. patients will be randomized in 2 groups regarding the hemodynamic management and catecholamin doses: Group 1…
- Trial name
- NCT04398069
- Testing
- hemodynamic optimisation aiming to achieve normal cerebral perfusion
- Where
- Tunisia
- Volunteers
- 24 people
- Sponsor
- Mongi Slim Hospital
Orofacial Pain, Tension-Type Headache
Photobiomodulation Dosimetry s in Patients With Orofacial Pain
This project aims to validate a dosimetry model for photobiomodulation treatment in patients with orofacial pain and tension-type headache symptoms. The study will involve 240 participants divided into four age groups.
- Trial name
- NCT06065969
- Testing
- Photobiomodulation
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Migraine, Pain
The Effects of a Long-lasting Infusion of Vasoactive Intestinal Peptide (VIP) in Episodic Migraine Patients
Vasoactive intestinal peptide (VIP) is a peptide of 28 amino acid residues that belongs to the glucagon/secretin superfamily of peptides.
- Conditions
- Migraine, Pain, Neurologic Manifestations, Signs and Symptoms
- Trial name
- NCT04260035
- Testing
- Vasoactive Intestinal Polypeptide (VIP), Sterile saline
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Danish Headache Center
Cerebral Palsy, Physical Inactivity
Effects of Modified Pilates Training on Hemodynamic Responses
Cerebral Palsy (CP) is a non-progressive neurodevelopmental disorder that starts in the early stages of life, causes activity limitation, and consists of movement and posture deficiencies.
- Conditions
- Cerebral Palsy, Physical Inactivity, Gait Disorders in Children, Gait, Spastic
- Trial name
- cp (NCT05221307)
- Testing
- exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Anesthesia
Cerebral Flow-metabolism Coupling During Adult Surgery
The brain is a highly active organ that requires a large blood flow to function properly. Normally, blood flow is tightly linked to the brain's energy demands.
- Trial name
- NCT05941494
- Testing
- Propofol, Sevoflurane, Ephedrine
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Jason Chui