Clinical trials: Central Venous Catheters, open to volunteers
Shock
Central Line Study
Two different techniques for placing a central venous catheter will be compared. The studyu team hypothesizes that clinicians randomized to the peripheral catheter technique will have higher first attempt success rates, fewer…
- Trial name
- NCT05534971
- Testing
- Central venous catheter insertion
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Montefiore Medical Center
Ventilator-Associated Pneumonia (VAP), Central Line-Associated Bloodstream Infection
Impact of Nurses' Behavior Change and Evidence-Based Practice Implementation on Quality Indicators in Intensive Care Units in Low- and Middle-Income Countries
Study title: Impact of nurses' behavior change and implementing evidence-based practice to improve quality indicators in intensive care units in low-and middle-income countries Background and Rationale: Quality care is crucial…
- Conditions
- Ventilator-Associated Pneumonia (VAP), Central Line-Associated Bloodstream Infection, Pressure Ulcers (Hospital-acquired Pressure Injuries), Prolonged Intensive Care Unit Length of Stay
- Trial name
- NCT07397364
- Testing
- Evidence based practices bundles of care
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Venous Thromboembolism, Cancer
Primary Thromboprophylaxis in Patients With Malignancy and Central Venous Catheters
The purpose of the full trial is to determine the efficacy and safety of prophylactic dose rivaroxaban to prevent VTE among cancer patients with CVC.
- Trial name
- TRIM-Line (NCT05029063)
- Testing
- Rivaroxaban 10 MG
- Where
- 11 sites in Canada
- Volunteers
- 1,828 people
- Sponsor
- Ottawa Hospital Research Institute
Device Related Infection, Vascular Access Complication
The IVCare Adaptive Platform Trial
The IVCare trial is a multicentre adaptive platform study evaluating interventions to prevent infections and other complications associated with central venous access devices (CVADs) in patients with newly inserted or existing…
- Conditions
- Device Related Infection, Vascular Access Complication, Device Related Sepsis, Catheter Infection
- Trial name
- NCT07587593
- Testing
- Connectors/Caps Domain - Standard of Care, Curos™, ClearGuard™ HD
- Volunteers
- 2,500 people
- Sponsor
- The University of Queensland
Infusions, Intravenous, Administration, Intravenous
Digital Transformation of Continuity of Care for Peripherally Inserted Central Catheters: SpadCare Experience
The study focuses on patients who require outpatient infusion of therapy ("Infusions, Intravenous"[Mesh]) "Administration, Intravenous"[Mesh] ("Home Infusion Therapy"[Mesh]) "Parenteral Nutrition, Home"[Mesh] via a peripherally…
- Conditions
- Infusions, Intravenous, Administration, Intravenous, Home Infusion Therapy, Parenteral Nutrition, Home
- Trial name
- SpadCare (NCT06905119)
- Testing
- Digital Transformation of Continuity of Care for Peripherally Inserted Central Catheters
- Where
- Spain
- Volunteers
- 201 people
- Sponsor
- Fundacion Miguel Servet
Ventilator Acquired Pneumonia, Central Line Associated Blood Stream Infections (CLABSI)
Evidence-Based Nursing to Reduce Adverse Events Regarding Ventilator Associated Pneumonia, Pressure Injuries and Central Line Bloodstream Infection in Intensive Care Unit in Bangladesh
Quality of care is crucial for preventing adverse events such as infection in the intensive care units (ICUs). The most common ICU-acquired infections include pneumonia such as Ventilator Associated Pneumonia (VAP), Pressure…
- Conditions
- Ventilator Acquired Pneumonia, Central Line Associated Blood Stream Infections (CLABSI), Pressure Ulcer (PU), Medical Device Related Pressure Ulcer (MDRPU)
- Trial name
- EBP in Nursing (NCT07299799)
- Testing
- Education with EBP, This is a pre- and post- quasi-experimental study.
- Where
- 2 sites in Bangladesh, Japan
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Hiroshima University
Cancer
Maintenance Optimization of the Fully Implanted Venous Catheter
Central venous catheter (CVC) are intravascular devices used in clinical practice, namely to administer fluid therapy, parenteral nutrition, drugs, blood products, hemodynamic monitoring, also being a gateway to the collection of…
- Trial name
- OTIMACAT (NCT05411666)
- Testing
- Saline solution maintenance of the CVC, No maintenance of the CVC
- Where
- Portugal
- Volunteers
- 176 people
- Sponsor
- Clinical Academic Center (2CA-Braga)
Anticoagulant-induced Bleeding, Direct Oral Anticoagulant
Peri-procedural Management of Direct Oral Anticoagulants for Central VENOus Catheters in CAncer Patients With Venous Thromboembolism or Atrial Fibrillation Pilot Study
The peri-procedural management of direct oral anticoagulants (DOACs) in persons with cancer (PWC) undergoing tunneled or port central venous catheter (CVC) insertion is a common but understudied clinical problem, with conflicting…
- Conditions
- Anticoagulant-induced Bleeding, Direct Oral Anticoagulant, Cancer, Central Venous Catheter
- Trial name
- VENO CAT (NCT06887270)
- Testing
- Continued DOAC, Interrupted DOAC
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University Health Network, Toronto
Peripherally Inserted Central Catheter, Umbilical Venous Catheter
Umbilical Venous Versus Peripherally Inserted Central Catheters in Neonates: A Prospective Cohort Study of Complications, Catheter Survival, and CLABSI"
This study aims to prospectively compare umbilical venous catheters (UVCs) and peripherally inserted central catheters (PICCs) in neonates, focusing on complications, catheter survival, and central line-associated bloodstream…
- Conditions
- Peripherally Inserted Central Catheter, Umbilical Venous Catheter, CLABSI - Central Line Associated Bloodstream Infection
- Trial name
- NCT07209670
- Testing
- peripherally inserted central catheter insertion, umbilical venous catheters insertion
- Volunteers
- 360 people
- Sponsor
- Assiut University
Atrial Fibrillation - Symptomatic
Low Voltage-Directed Catheter Ablation for Atrial Fibrillation
A two-pronged approach to evaluate long term success of non-paroxysmal ablation when using a: 1. specified low voltage-directed with pulmonary vein isolation (LD+PVI) approach compared to , 2.
- Trial name
- NCT03355456
- Testing
- Radiofrequency ablation
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Ohad Ziv
Central Line Associated Blood Stream Infections (CLABSI)
Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults And Adolescent Participants Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)
This is a Phase 3, randomized, double-blind, controlled, adaptive, 2-arm, multicenter study to demonstrate the efficacy and safety of DefenCath in adult and adolescent participants receiving home Total Parenteral Nutrition (TPN)…
- Trial name
- NCT06822426
- Testing
- (taurolidine and heparin) catheter lock solution, Heparin
- Where
- 24 sites in United States, Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- CorMedix Therapeutics
Central Line-Associated Bloodstream Infection (CLABSI), Bacteremia
Evaluation of an AI-Assisted Tool for CLABSI Surveillance at VA Medical Centers
Infection prevention and control programs at US hospitals perform surveillance to detect and publicly report hospital-onset central line-associated bloodstream infections (CLABSI) using standards set by CDC's National Healthcare…
- Conditions
- Central Line-Associated Bloodstream Infection (CLABSI), Bacteremia, Bloodstream Infections
- Trial name
- VA-AI-CLABSI (NCT07918352)
- Testing
- Generative AI tool for CLABSI surveillance
- Volunteers
- 30 people
- Sponsor
- University of Maryland, Baltimore
Vasoconstriction, Biomarkers
Immersive VR to Reduce Stress, Anxiety, and Pain During PICC/Midline Placement
Medical and technological advancements allow increasingly complex invasive procedures to be performed on hospitalized patients, improving their survival rates and prognosis.
- Conditions
- Vasoconstriction, Biomarkers, Central Venous Catheters, Midline Catheter
- Trial name
- PICC (NCT07696156)
- Testing
- Immersive Virtual Reality, Peripherally Inserted Central Catheter (PICC), Mepivacaine 2% Injection
- Where
- 4 sites in Spain
- Volunteers
- 202 people
- Sponsor
- diana garcia
CLABSI - Central Line Associated Bloodstream Infection, CRBSI - Catheter Related Bloodstream Infection
Neonatal Catheter Lock for Infection Prevention
For newborns admitted to Neonatal Intensive Care Units (NICUs), one of the main risk factors for late-onset sepsis is the presence of a central venous catheter (CVC), which is often essential for the administration of medications…
- Conditions
- CLABSI - Central Line Associated Bloodstream Infection, CRBSI - Catheter Related Bloodstream Infection, Neonatal Sepsis, Late-Onset
- Trial name
- Neo-CLIP (NCT07585188)
- Testing
- Taurolidine 2% lock, Normal saline lock
- Where
- Italy
- Volunteers
- 576 people
- Sponsor
- University of Turin, Italy
Central Line Associated Blood Stream Infections (CLABSI)
Machine Learning Prediction of Possible Central Line Associated Blood Stream Infections and Rate of Reduction
Prospective, multi-center, cluster-randomized trial of a hospital Infection Preventionist (IP)-led quality improvement study to provide clinical teams with just-in-time clinical education and reinforcement of existing best…
- Trial name
- CLABSI AI (NCT07108660)
- Testing
- Infection Preventionist Led Best Practices Reminders
- Where
- 19 sites in United States
- Volunteers
- 17,800 people
- Sponsor
- Swedish Medical Center
CLABSI - Central Line Associated Bloodstream Infection
Epidemiological Investigation of Central Venous Catheter-related Bloodstream Infections in Icus in China
In recent years, with the rapid advancement of medical technology and the rapid development of critical care medicine, the use of various central venous catheters in icus has been increasing day by day.
- Trial name
- NCT07255105
- Where
- China
- Volunteers
- 1,846 people
- Sponsor
- Jianfeng Xie
Central Venous Catheter, Point of Care Ultrasound (POCUS)
Central Venous Catheter Placement With Thoracic Ultrasound and Intracavity ECG Positioning
The goal of this interventional study is to assess the feasibility of two bedside techniques for confirming central venous catheter (CVC) placement and detecting complications: Intracavity ECG monitoring to confirm internal…
- Conditions
- Central Venous Catheter, Point of Care Ultrasound (POCUS), Intracavitary Electrocardiogram Guiding, Feasibility Studies
- Trial name
- CVC-TIP (NCT07291869)
- Testing
- Intracavity ECG, Thoracic point of care ultrasound
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- York Teaching Hospitals NHS Foundation Trust
Congenital Heart Disease, Unfractionated Heparin
Comparison of the Best Method for Measuring Anti-Xa Activity in Children Receiving Unfractionated Heparin in Cardiac Intensive Care (COMPAXE-HNF)
This study aims to compare the accuracy of two different blood sampling methods from a central venous catheter (CVC) for measuring anti-Xa activity in children receiving unfractionated heparin (UFH) from this CVC.
- Conditions
- Congenital Heart Disease, Unfractionated Heparin, Anti Xa Activity
- Trial name
- COMPAXE-HNF (NCT07365670)
- Testing
- blood sampling for measuring anti-Xa activity, measurement of anti-XA activity
- Volunteers
- 22 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Atrial Fibrillation, Persistent Atrial Fibrillation
PFA-based Bi-atrial Maze-like Catheter Ablation for PeAF
In radiofrequency (RF) ablation of persistent atrial fibrillation (PeAF), the additional linear ablation beyond pulmonary vein isolation (PVI) does not yield an reduce atrial arrhythmias recurrences.The goal of this clinical…
- Trial name
- PEACE-AF (NCT06952023)
- Testing
- Modified Maze ablation with PFA, PVI only with PFA
- Where
- 3 sites in China
- Volunteers
- 390 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Infants, Intensive Care Unit
Open Surgical, Modified Seldinger's and US Techniques for Jugular Central Line Insertion in Infants
The aim of this study was to compare the three approaches: open technique, modified Seldinger's technique and closed ultrasound-guided Central venous catheterization insertion for central line insertion in infancy as regards…
- Conditions
- Infants, Intensive Care Unit, Central Venous Catheterization
- Trial name
- NCT06862492
- Testing
- Open surgical cut down technique, Modified Seldinger's technique, Closed Ultrasound guided CVC insertion
- Where
- Egypt
- Volunteers
- 35 people
- Sponsor
- Tanta University