Clinical trials: Central Venous Catheterization, open to volunteers
Shock
Central Line Study
Two different techniques for placing a central venous catheter will be compared. The studyu team hypothesizes that clinicians randomized to the peripheral catheter technique will have higher first attempt success rates, fewer…
- Trial name
- NCT05534971
- Testing
- Central venous catheter insertion
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Montefiore Medical Center
Infusions, Intravenous, Administration, Intravenous
Digital Transformation of Continuity of Care for Peripherally Inserted Central Catheters: SpadCare Experience
The study focuses on patients who require outpatient infusion of therapy ("Infusions, Intravenous"[Mesh]) "Administration, Intravenous"[Mesh] ("Home Infusion Therapy"[Mesh]) "Parenteral Nutrition, Home"[Mesh] via a peripherally…
- Conditions
- Infusions, Intravenous, Administration, Intravenous, Home Infusion Therapy, Parenteral Nutrition, Home
- Trial name
- SpadCare (NCT06905119)
- Testing
- Digital Transformation of Continuity of Care for Peripherally Inserted Central Catheters
- Where
- Spain
- Volunteers
- 201 people
- Sponsor
- Fundacion Miguel Servet
Vasoconstriction, Biomarkers
Immersive VR to Reduce Stress, Anxiety, and Pain During PICC/Midline Placement
Medical and technological advancements allow increasingly complex invasive procedures to be performed on hospitalized patients, improving their survival rates and prognosis.
- Conditions
- Vasoconstriction, Biomarkers, Central Venous Catheters, Midline Catheter
- Trial name
- PICC (NCT07696156)
- Testing
- Immersive Virtual Reality, Peripherally Inserted Central Catheter (PICC), Mepivacaine 2% Injection
- Where
- 4 sites in Spain
- Volunteers
- 202 people
- Sponsor
- diana garcia
Stroke
Comparative Study of the Effects of Dry Needling and Botulinum Toxin Type A as a Treatment for Lower Limb Post-stroke Spasticity
This is a randomized parallel group clinical trial which will be conducted in three countries (Spain, Canada and Belgium) comparing Botulinum Toxin type A (BTX-A) and Dry Needling (DN) effectiveness for post-stroke spasticity in…
- Trial name
- STROKEPOC (NCT06296082)
- Testing
- Botulinum toxin type A, Dry Needling
- Where
- 3 sites in Belgium, Canada and 1 more
- Volunteers
- 90 people
- Sponsor
- Universiteit Antwerpen
Critical Illness
The INVADE Study: INnominate Vein Approach for Central Catheterization in Difficult to cannulatE Patients
Most recent guidelines suggest central venous access must be performed with real-time ultrasound guidance, and the most recommended site for cannulation is internal jugular vein (IJV); however, it is recognized that evidence for…
- Trial name
- INVADE (NCT04265703)
- Testing
- Internal jugular vein catheterization, Subclavian vein catheterization, Innominate vein catheterization
- Where
- Mexico
- Volunteers
- 315 people
- Sponsor
- Hospital Civil de Guadalajara
Tension-Type Headache, Chronic Tension-type Headache
Efficacy of a Multimodal Physiotherapy Program and Mobile-App Guided Meditation in Adults With Frequent or Chronic Tension-Type Headache
The goal of this clinical trial is to evaluate whether a multimodal physiotherapy program and guided meditation using a mobile app can help reduce headache pain and improve quality of life in adults with frequent or chronic…
- Conditions
- Tension-Type Headache, Chronic Tension-type Headache, Frequent Episodic Tension-Type Headache
- Trial name
- JBE-CEF (NCT07240532)
- Testing
- Multimodal Physiotherapy for Tension-Type Headache, Guided Meditation Using Insight Timer App
- Where
- Spain
- Volunteers
- 78 people
- Sponsor
- Universidad de Granada
Infants, Intensive Care Unit
Open Surgical, Modified Seldinger's and US Techniques for Jugular Central Line Insertion in Infants
The aim of this study was to compare the three approaches: open technique, modified Seldinger's technique and closed ultrasound-guided Central venous catheterization insertion for central line insertion in infancy as regards…
- Conditions
- Infants, Intensive Care Unit, Central Venous Catheterization
- Trial name
- NCT06862492
- Testing
- Open surgical cut down technique, Modified Seldinger's technique, Closed Ultrasound guided CVC insertion
- Where
- Egypt
- Volunteers
- 35 people
- Sponsor
- Tanta University
Chronic Migraine, Tension-type Headache
Fire Needling Plus Filiform Needling for Chronic Migraine With Comorbid Tension-Type Headache
The investigators conducted a multicenter, prospective, randomized controlled clinical study to learn whether fire needling combined with filiform needling applied to pericranial muscle tenderness areas can effectively treat…
- Trial name
- NCT07633522
- Testing
- filiform needling, fire needling combined with filiform needling
- Where
- 3 sites in China
- Volunteers
- 88 people
- Sponsor
- Beijing Hospital of Traditional Chinese Medicine
Migraine Without Aura
Efficacy and Mechanism of Fu's Subcutaneous Needling Treatment for Migraine Without Aura
This study aimed to compare the analgesic efficacy and quality-of-life improvement between FSN and flunarizine hydrochloride in patients with migraine without aura.
- Trial name
- NCT07068815
- Testing
- Fu's Subcutaneous Needling, Flunarizine Hydrochloride
- Volunteers
- 60 people
- Sponsor
- Guangzhou University of Chinese Medicine
Tension-Type Headache
HVLAT, Electric DN, Exercise Vs. Mobilization, STM, Exercise, TENS for Tension Type Headaches
The purpose of this research is to compare two different approaches for treating patients with tension-type headaches: thrust Manipulation, electric dry Needling and exercise Vs.
- Trial name
- NCT04609709
- Testing
- Thrust Manipulation, Electric Dry Needling and Exercise, Non-thrust Mobilization, Soft-Tissue Mobilization, Exercise and TENS
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Alabama Physical Therapy & Acupuncture
Cannulation of Internal Jugular Vein
Comparison of Short-Axis and Long-Axis Internal Jugular Vein Cannulation for First-Pass Success
To compare the frequency of first pass success by short axis versus long axis for cannulation of internal jugular vein.
- Trial name
- NCT07691554
- Testing
- Short-Axis Ultrasound-Guided Internal Jugular Vein Cannulation, Long-Axis Ultrasound-Guided Internal Jugular Vein Cannulation
- Where
- Pakistan
- Volunteers
- 10 people
- Sponsor
- University of Health Sciences Lahore
Prophylactic, Anticoagulation
Prophylactic Anticoagulation for Central Venous Line Insertion in Critically Ill Children
This will be a Prospective, randomized, open- label, parallel-group, center trial, which will include 80 of Children which will be admitted at Pediatric Intensive Care Unit (PICU) of Menoufia university Hospital from August 2026…
- Trial name
- NCT07710482
- Testing
- Enoxaparin
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Menoufia University
Dry Needling, Dry Cupping
Dry Needling Versus Dry Cupping on Pain and Disability in Cervicogenic Headache Patients
This study aims to compare the added effects of dry needling and dry cupping to conventional physical therapy on headache pain intensity, headache frequency, headache duration, upper cervical range of motion, and disability…
- Conditions
- Dry Needling, Dry Cupping, Cervicogenic Headache
- Trial name
- NCT06689371
- Testing
- Group A (Dry Needling), Group B (Dry cupping), Group C (control)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
Frailty, Cardiac Surgery
Frailty and Ultrasound-Guided Central Venous Catheterization Difficulty in Adult Cardiac Surgery Patients
This prospective observational study aims to evaluate the association between preoperative frailty and the procedural difficulty of ultrasound-guided internal jugular vein catheterization in adult patients undergoing elective…
- Conditions
- Frailty, Cardiac Surgery, Central Venous Catheter
- Trial name
- FRAILCVC (NCT07701538)
- Testing
- Ultrasound-Guided Internal Jugular Vein Catheterization
- Where
- Turkey (Türkiye)
- Volunteers
- 280 people
- Sponsor
- Ankara City Hospital Bilkent
Central Vein Catheter, Ultrasound
Ultrasound Guidance vs Landmark Technique for Internal Jugular Vein Catheterization
Central venous catheterization (CVC) is a fundamental procedure in anesthesiology and reanimation practice for critical clinical processes such as hemodynamic monitoring, vasoactive drug infusion, and fluid resuscitation.
- Trial name
- NCT07701746
- Testing
- Ultrasound Guidance, Landmark Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Catheter Malposition, Central Venous Catheterization
Ultrasound Guidance vs. Landmark Technique for Catheter Malposition in IJV Catheterization
Central venous catheterization (CVC) via the internal jugular vein (IJV) is a fundamental procedure in anesthesia and intensive care for hemodynamic monitoring, fluid resuscitation, and vasoactive drug administration.
- Trial name
- NCT07701720
- Testing
- Ultrasound-Guided Technique, Landmark Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Cervicogenic Headache, Whiplash Injuries
Manipulation and Dry Needling in Patients With Cervicogenic Headache and WAD II
The purpose of this research is to compare two different approaches for treating patients with cervicogenic headaches associated with type II whiplash associated disorder: non-thrust mobilization and exercise versus thrust…
- Trial name
- NCT06502951
- Testing
- Dry Needling,Thrust Manipulation, Exercise,Non-thrust Mobilization
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Alabama Physical Therapy & Acupuncture
Headache Disorders, Primary, Headache, Cervicogenic
Effect of Ultrasound-Guided Dry Needling Targeting Rectus Capitus Posterior Major on Individuals With Headaches
Headaches such as tension-type, migraine, and cervicogenic (neck-related) headaches are among the most common and disabling conditions worldwide.
- Trial name
- NCT07309874
- Testing
- Dry needling
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Texas Tech University Health Sciences Center
Anticoagulants and Bleeding Disorders
Comparison of Heparin Anti-Xa Activity From Central Venous Catheter Samples Using a 5 mL Syringe Flush or a Vacuum Tube Flush Versus Peripheral Vein Samples in ICU Patients
The goal is to investigate whether blood samples drawn from a central venous catheter can provide reliable measurements of unfractionated heparin (UFH) anti-Xa activity, compared to the standard method of peripheral vein…
- Trial name
- CASSANDRA (NCT07183605)
- Testing
- catheter flushing techniques
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Vascular Access, Elevated Jugular Venous Pressure
Ultrasound Assessment of Internal Jugular Vein for Cannulation and Venous Pressure Prediction
This prospective observational study aims to evaluate the diagnostic utility of vascular ultrasound for internal jugular vein (IJV) assessment in adult patients undergoing clinically indicated IJV cannulation.
- Conditions
- Vascular Access, Elevated Jugular Venous Pressure, Hemodynamic Instability
- Trial name
- NCT07773506
- Volunteers
- 100 people
- Sponsor
- Assiut University