Central Vein CatheterNCT07701746
Ultrasound Guidance vs Landmark Technique for Internal Jugular Vein Catheterization
An observational study of Central Vein Catheter and Ultrasound, run by Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital at 1 site in Turkey (Türkiye).
Trial summary
Central venous catheterization (CVC) is a fundamental procedure in anesthesiology and reanimation practice for critical clinical processes such as hemodynamic monitoring, vasoactive drug infusion, and fluid resuscitation. Read more about this study
- Who is it for?
- Ages 18 to 75 yearsHealthy volunteers can take part
- Conditions the study is for
- Central Vein Catheter, Ultrasound
- What is being tested?
- Ultrasound Guidance and Landmark Technique
- Type of treatment
- Surgery or procedure
- How many people
- 144 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Jul 2026to 30 Sep 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 75 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: The study population consists of patients aged 18 to 75 years who are scheduled to undergo surgery in the general operating room unit at Dicle University Faculty of Medicine Hospital and require the insertion of a central venous catheter. All included patients will receive standard general anesthesia following an 8-hour fasting period
Who may be able to join
- Patients aged 18-75 years
- Patients operated on in the general operating room unit
- Patients undergoing central venous catheter insertion
Who cannot join
- Refusal to participate in the study
- Patients aged under 18 or over 75 years
- Patients undergoing emergency surgery
- Presence of coagulopathy
- History of infection, operation, or cannulation in the intervention area
- Allergy to USG gel
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site
Dicle University
Diyarbakır, Eyalet/Yerleşke, 21070
About this study
Official title: The Effect of Ultrasound Guidance Versus Landmark Technique on the Number of Needle Redirections in Internal Jugular Vein Catheterization
Central venous catheterization (CVC) is a fundamental procedure in anesthesiology and reanimation practice for critical clinical processes such as hemodynamic monitoring, vasoactive drug infusion, and fluid resuscitation. The internal jugular vein (IJV) is frequently preferred due to its superficial anatomical location and ease of access. This study aims to observe and compare the ultrasound (USG) guidance and the landmark method in patients scheduled for IJV catheterization.
Read the detailed description
Traditionally, IJV catheterization applied with a blind technique based on anatomical landmarks is increasingly being replaced by USG-guided applications. However, the landmark method is still actively and widely used in the field due to equipment limitations or practical habits. A total of 144 patients aged 18-75 who are operated on in the general operating room unit and have a central venous catheter inserted will be included in this prospective study. Patients will be divided into two groups: those receiving USG-guided catheterization (n=72) and those receiving the landmark technique (n=72). All patients will receive standard general anesthesia after an 8-hour fasting period. The physician performing the cannulation with USG will have at least 2 years of USG experience and/or a certificate.
- Conditions
- Central Vein Catheter, Ultrasound
- Being tested
- Ultrasound Guidance, Landmark Technique
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Ultrasound GuidanceProcedure or surgery
Patients (n=72) receiving internal jugular vein catheterization performed with ultrasound guidance by an anesthesiologist with at least 2 years of USG experience or certification.
Landmark TechniqueProcedure or surgery
Patients receiving internal jugular vein catheterization performed using the traditional blind/anatomical landmark technique (typically by residents or clinicians gaining experience).
| Study group | Role | What they receive |
|---|---|---|
| Ultrasound guided central venous catheterisation | Patients (n=72) receiving internal jugular vein catheterization performed with ultrasound guidance by an anesthesiologist with at least 3 years of USG experience or certification. Receives: Procedure: Ultrasound Guidance | |
| Landmark technique | Patients (n=72) receiving internal jugular vein catheterization performed using the traditional blind/anatomical landmark technique (typically by residents or clinicians gaining experience). Receives: Procedure: Landmark Technique |
What is being measured
The primary outcome is the main question the study is designed to answer.
Number of Needle Redirections.
Measured: Intraoperative.
Secondary outcomes (2)
First-Attempt Success Rate
Measured: Intraoperative
Total Access Time
Measured: Intraoperative, up to 15 minutes
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Jul 2026
- Study start1 Jul 2026
- Primary completion15 Sep 2026 (estimated)
- Study completion30 Sep 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Central Vein CatheterStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Prospective
- Enrolment
- 144 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Fikret Salık, Dicle University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07701746
- Sponsor's protocol ID
- 320/2026
- Status last verified
- Aug 2026
- First submitted
- 8 Jul 2026
- Last updated
- 2 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Sazdov D, Srceva MJ, Todorova ZN. Comparative Analysis of Ultrasound Guided Central Venous Catheterization Compared to Blind Catheterization. Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2017 Sep 1;38(2):107-114. doi: 10.1515/prilozi-2017-0028.
PubMed 28991766
Study at a glance
From the registry record, last updated by the sponsor on 2 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Ultrasound Guidance Versus Landmark Technique on the Number of Needle Redirections in Internal Jugular Vein Catheterization
- ClinicalTrials.gov ID
- NCT07701746
- Acronym / sponsor ID
- 320/2026
- Conditions
- Central Vein Catheter, Ultrasound
- Study type
- Observational
- Recruitment status
- Enrolling by invitation
- Enrolment
- 144 participants (estimated)
- Lead sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research HospitalUniversity, hospital or other
- Study start
- 1 Jul 2026 (actual)
- Primary completion
- 15 Sep 2026 (estimated)
- Study completion
- 30 Sep 2026 (estimated)
- First posted
- 14 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Central venous catheterization (CVC) is a fundamental procedure in anesthesiology and reanimation practice for critical clinical processes such as hemodynamic monitoring, vasoactive drug infusion, and fluid resuscitation. The internal jugular vein (IJV) is frequently preferred due to its superficial anatomical location and ease of access. This study aims to observe and compare the ultrasound (USG) guidance and the landmark method in patients scheduled for IJV catheterization.
Detailed description
Traditionally, IJV catheterization applied with a blind technique based on anatomical landmarks is increasingly being replaced by USG-guided applications. However, the landmark method is still actively and widely used in the field due to equipment limitations or practical habits. A total of 144 patients aged 18-75 who are operated on in the general operating room unit and have a central venous catheter inserted will be included in this prospective study. Patients will be divided into two groups: those receiving USG-guided catheterization (n=72) and those receiving the landmark technique (n=72). All patients will receive standard general anesthesia after an 8-hour fasting period. The physician performing the cannulation with USG will have at least 2 years of USG experience and/or a certificate.
Study design
- Observational model
- Case-control
- Time perspective
- Prospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Ultrasound guided central venous catheterisation | – | Procedure: Ultrasound GuidancePatients (n=72) receiving internal jugular vein catheterization performed with ultrasound guidance by an anesthesiologist with at least 3 years of USG experience or certification. |
| Landmark technique | – | Procedure: Landmark TechniquePatients (n=72) receiving internal jugular vein catheterization performed using the traditional blind/anatomical landmark technique (typically by residents or clinicians gaining experience). |
Who may qualify
- Ages
- 18 to 75 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- The study population consists of patients aged 18 to 75 years who are scheduled to undergo surgery in the general operating room unit at Dicle University Faculty of Medicine Hospital and require the insertion of a central venous catheter. All included patients will receive standard general anesthesia following an 8-hour fasting period
Key inclusion criteria (3 listed)
- Patients aged 18-75 years
- Patients operated on in the general operating room unit
- Patients undergoing central venous catheter insertion
Key exclusion criteria (6 listed)
- Refusal to participate in the study
- Patients aged under 18 or over 75 years
- Patients undergoing emergency surgery
- Presence of coagulopathy
- History of infection, operation, or cannulation in the intervention area
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Ultrasound GuidancePatients (n=72) receiving internal jugular vein catheterization performed with ultrasound guidance by an anesthesiologist with at least 2 years of USG experience or certification. | Procedure or surgery | Ultrasound guided central venous catheterisation |
| Landmark TechniquePatients receiving internal jugular vein catheterization performed using the traditional blind/anatomical landmark technique (typically by residents or clinicians gaining experience). | Procedure or surgery | Landmark technique |
Primary outcome
Number of Needle Redirections.
Time frame: Intraoperative.
2 secondary outcomes
First-Attempt Success Rate
Time frame: Intraoperative
Total Access Time
Time frame: Intraoperative, up to 15 minutes
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Sep 2026.
- Background: PubMed 28991766Sazdov D, Srceva MJ, Todorova ZN. Comparative Analysis of Ultrasound Guided Central Venous Catheterization Compared to Blind Catheterization. Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2017 Sep 1;38(2):107-114. doi: 10.1515/prilozi-2017-0028.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Central Vein Catheter and Ultrasound, run by Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 2 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Number of Needle Redirections. (time frame: Intraoperative.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07701746, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Sep 2026.