Clinical trials: Central Pain Syndrome
Temporomandibular Disorder, Temporomandibular Joint Disorders
Effect of Exercises on Convergence Insufficiency in Individuals With Temporomandibular Disorders
Temporomandibular Disorder is a disorder that involves the muscles of mastication, the temporomandibular joint (TMJ), and associated structures.
- Conditions
- Temporomandibular Disorder, Temporomandibular Joint Disorders, Temporomandibular Joint Dysfunction Syndrome, Convergence Insufficiency
- Trial name
- NCT05761106
- Testing
- Oculomotor Therapy, Therapy for Temporomandibular Disorder
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- University of Nove de Julho
Cachexia, Lymphoma
Celecoxib in Managing Pain, Weight Loss, and Weakness in Patients With Advanced Cancer
RATIONALE: Celecoxib may help relieve moderate or severe pain associated with cancer. It may also decrease weight loss and improve muscle strength in cancer patients.
- Conditions
- Cachexia, Lymphoma, Melanoma (Skin), Ovarian Cancer
- Trial name
- NCT00093678
- Testing
- celecoxib, anticachectic therapy, nutritional support
- Sponsor
- Eastern Cooperative Oncology Group
Migraine, Healthy
Molecular and Functional PET-fMRI Measures of Analgesia in Migraine
The placebo effect is a phenomenon that has experienced major advances of its understanding in the last decade. However, mechanisms of placebo analgesia in chronic pain patients have yet to be compared to healthy subjects.
- Trial name
- NCT01970943
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Stroke
MTPr With Shockwave on Pain & Function of SHS in Stroke
Background: shoulder-hand syndrome is considered a significant reason for the reduction of upper limb functions after stroke. Purpose: To investigate the influence of Myofascial Trigger Points (MTrPs) release and shockwave…
- Trial name
- NCT04627636
- Testing
- Myofascial trigger points pressure (MTrP) release, Shockwave therapy application, conventional therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- October 6 University
Bladder Outlet Obstruction, Multiple Sclerosis
GentleCath™ for Men Intermittent Catheter With FeelClean™ Technology
Male self catherterisng observational study.
- Conditions
- Bladder Outlet Obstruction, Multiple Sclerosis, Cauda Equina Syndrome, Enlarged Prostate With Lower Urinary Tract Symptoms
- Trial name
- NCT05470751
- Testing
- Intermittent self-catheterisation
- Where
- 16 sites in United States, France and 1 more
- Volunteers
- 72 people
- Sponsor
- ConvaTec Inc.
Migraine, Abdominal Pain
Migraine and Recurrent Abdominal Pain in Children
This study will evaluate a new model for assessing and treating migraine and recurrent abdominal pain in children. The model combines behavioral techniques such as relaxation training with biologic components such as thermal…
- Trial name
- NCT00060619
- Testing
- thermal biofeedback, relaxation training, cognitive coping skills
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Stroke
Effects of Task-Based Mirror Therapy for Post-stroke Shoulder-Hand Syndrome
The study aims to determine the effects of task-based mirror therapy on edema, pain and upper limb motor function with shoulder-hand syndrome in post stroke patients.
- Trial name
- NCT07428811
- Testing
- Task based mirror therapy, Conventional exercises
- Where
- 2 sites in Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Irritable Bowel Syndrome
Characterization of Pain Processing Mechanisms in Irritable Bowel Syndrome
The purpose of this study is to provide new information and to determine which kinds of brief, tolerable, experimental pain are affected by the drugs being studied in patients with irritable bowel syndrome, a disease that causes…
- Trial name
- NCT00100425
- Testing
- Viceral Perception Testing
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Spinal Cord Injuries, Myofascial Pain Syndrome
Effectiveness of Dry Needling as a Treatment of Shoulder Myofascial Pain Syndrome in Spinal Cord Injury Patients
Shoulder pain in people with spinal cord injury is one of the most prevalent in acute and chronic patients because of weakness in shoulder periarticular muscles, and also because of overuse of these part of the body in assistive…
- Conditions
- Spinal Cord Injuries, Myofascial Pain Syndrome, Shoulder Pain, Puncture
- Trial name
- NCT03709797
- Testing
- Dry needling in infraspinatus muscle
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad de León
Borderline Personality Disorder
Clinical Research Study to Evaluate Selegiline in the Treatment of Borderline Personality Disorder
Selegiline is superior to placebo in improving psychological and physical functioning in patients with Borderline Personality Disorder.
- Trial name
- NCT01912391
- Testing
- Selegiline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mood and Anxiety Research, Inc
Migraine, Pain, Shoulder
Effects of MTRPs Therapy in Migraine.
Case series, repeated-measures design, pilot study. Adult, female, migraine patients underwent seven Ischemic Compression Myofascial Trigger Points (IC-MTrPs) therapy sessions.
- Conditions
- Migraine, Pain, Shoulder, Trapezius Muscle Strain Left, Trapezius Muscle Strain Right
- Trial name
- MTRPs (NCT05646160)
- Testing
- Ischemic Compression of Myofascial Trigger Points (IC-MTRPs)
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Józef Piłsudski University of Physical Education
Low Back Pain, Chronic
Person-Centered Lifestyle Redesign in Chronic Low Back Pain
This study is designed to examine the effects of a person-centered lifestyle intervention on pain, occupational performance, quality of life, disability, physical activity levels, and mental status in individuals with chronic low…
- Trial name
- NCT07163546
- Testing
- Lifestyle intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Hacettepe University
Atherosclerosis, Stroke
Vascular Inflammation Imaging Using Somatostatin Receptor Positron Emission Tomography
This VISION study aims to investigate the role of inflammation in atherosclerosis using 68Ga- DOTATATE PET, and to validate 68Ga-DOTATATE PET imaging for the detection and quantification of vascular inflammation in the aorta…
- Conditions
- Atherosclerosis, Stroke, Transient Ischemic Attack, Chronic Stable Angina
- Trial name
- VISION (NCT02021188)
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- University of Cambridge
Аcute Coronary Syndrome
Registry of Acute Coronary Syndrome in the Regional Cardiovascular Center
The study is a prospective registry of patients consequently admitted to the regional cardiovascular center with a diagnosis of acute coronary syndrome, in order to study the behavior of patients from the first minutes of the…
- Trial name
- STOCS (NCT06845384)
- Where
- Russia
- Volunteers
- 555 people
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Migraine Disorders, Facial Pain Disorder, Cluster Headache, Trigeminal Neuralgia, Trigeminal Autonomic Cephalalgias
Sphenopalatine Ganglion Pulsed Radiofrequency Treatment Outcomes
Purpose of the Study: This study aims to evaluate the clinical effectiveness and long-term outcomes of "Sphenopalatine Ganglion (SPG) Pulsed Radiofrequency (PRF)" treatment in patients with chronic headaches and facial pain.
- Trial name
- SPG-PRF (NCT07370142)
- Testing
- Pulsed Radiofrequency of the Sphenopalatine Ganglion
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Ankara City Hospital Bilkent
Stroke, Ischemic, Coronary Artery Disease
BuqitongluO Granule for Qi Deficiency and Blood Stasis Syndrome
The main purpose of this trial is to evaluate the efficacy and safety of Buqitongluo Granule in treating qi deficiency and blood stasis syndrome, and explore the effect of the improvement of qi deficiency and blood stasis…
- Conditions
- Stroke, Ischemic, Coronary Artery Disease, Angina Pectoris, Stable, Diabetic Peripheral Neuropathy
- Trial name
- BOSS (NCT04408261)
- Testing
- Buqitongluo Granule, Standard care
- Where
- China
- Volunteers
- 432 people
- Sponsor
- Dongzhimen Hospital, Beijing
Knee Osteoarthritis, Chronic Knee Pain
Selective Nerve Ablation for Chronic Knee Pain: A Retrospective Study
SAVE-KNEE is a single-center retrospective observational cohort study evaluating outcomes of ultrasound-guided cryoneurolysis, radiofrequency ablation and chemical neurolysis for chronic knee pain in routine clinical care.
- Trial name
- SAVE-KNEE (NCT07835672)
- Testing
- Ultrasound-Guided Cryoneurolysis, Ultrasound-Guided Radiofrequency Ablation, Ultrasound-Guided Chemical Neurolysis
- Where
- Poland
- Volunteers
- 746 people
- Sponsor
- Michał Bartoszewicz
Spinal Cord Injuries, Central Pain Syndrome
Effect of Preventional Drug Therapy on Pain Regulation Mechanisms Among SCI
Central neuropathic pain (CNP) is defined as chronic pain due to injury or disease in the central nervous system. This pain is most common among people with a spinal cord injuries (SCI), with a prevalence of about 50%.
- Trial name
- NCT03748290
- Testing
- Pregabalin
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Sheba Medical Center
Interstitial Cystitis/Painful Bladder Syndrome, Myofascial Pelvic Pain
Interstitial Cystitis: Examination of the Central Autonomic Network
This proposal aims to move the science of chronic pelvic pain (CPP) from simple associations towards an investigation of cause and effect relationships.
- Trial name
- ICECAN (NCT03008382)
- Testing
- Metoprolol Tartrate Oral Tablet, No intervention- observational sub-study
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Femoroacetabular Impingement Syndrome
AI-Based Screening and Diagnostic Models for Femoroacetabular Impingement Syndrome (FAIS-AI)
Femoroacetabular impingement syndrome (FAIS) is the leading cause of hip pain in young adults and frequently progresses to osteoarthritis, often exacerbated by delayed diagnosis in primary care.
- Trial name
- FAIS-AI (NCT07737223)
- Where
- China
- Volunteers
- 2,617 people
- Sponsor
- ChunBao Li