Clinical trials: Central Line Catheters
Difficult Intravenous Access
Central Venous Catheter vs Midline in Difficulty Access Patient - Pilot Trial
Intravenous access is a necessity for nearly all inpatient medical care. Approximately half of hospitalized patients require a peripheral venous catheter (PVC), either to enable administration of medications intravenously or to…
- Trial name
- p-ACCESS-D (NCT06719869)
- Testing
- Midline intravenous catheter, Central Venous Catheter (CVC):
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Region Jönköping County
Central Venous Catheter Thrombosis, Central Venous Catheter Related Bloodstream Infection
Central Venous Catheter-related Complications in Patients Under Anticancer Treatment
Oncology and hemotology patients under anticancer treatments are exposed to increased risks of central venous catheter-related complications due to the underlying cancer and its treament.
- Conditions
- Central Venous Catheter Thrombosis, Central Venous Catheter Related Bloodstream Infection, Solid Tumor, Hematologic Malignancy
- Trial name
- KTcCHO (NCT05455866)
- Testing
- central venous catheter
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Alpes Leman
Atrial Fibrillation
First Line Radiofrequency Ablation Versus Antiarrhythmic Drugs for Atrial Fibrillation Treatment (The RAAFT Study)
The purpose of this study is to determine whether catheter-based pulmonary vein isolation is superior to antiarrhythmic drugs as first line therapy in patients with symptomatic paroxysmal recurrent atrial fibrillation not…
- Trial name
- RAAFT (NCT00392054)
- Testing
- Pulmonary Vein Isolation performed by Catheter Ablation, Conventional Antiarrhythmic Drug Therapy
- Where
- 16 sites in United States, Canada and 3 more
- Volunteers
- 127 people
- Sponsor
- Population Health Research Institute
Catheter-Related Infections
Impact of a Task Delegation to ICU Nurses for Midlines' Placement
The administration of medication, fluid resuscitation, or even nutrition in intensive care unit (ICU) patients, requires one or more infusion lines which can be peripheral or central.
- Trial name
- IDEM (NCT04155723)
- Where
- France
- Volunteers
- 310 people
- Sponsor
- Groupe Hospitalier de Bretagne Sud
Central Line-associated Bloodstream Infection (CLABSI)
Port Protectors for Prevention of CLABSIs in Respiratory Semi-intensive Care Unit
Central Line-Associated BloodStream Infections (CLABSIs) are responsible for many deaths in the United States annually. Several collaboratives have demonstrated the preventability of these infections.
- Trial name
- NCT03486093
- Testing
- Training and retraining to GAVECELT "bundle" recommendations plus port protector, Training and retraining to GAVECELT "bundle" recommendations
- Volunteers
- 132 people
- Sponsor
- Catholic University of the Sacred Heart
Cancer, Central Venous Catheterization
Study of Sodium Bicarbonate in Restoring Blocked Catheters
This is a study looking at the use of sodium bicarbonate to restore the flow of blocked central line devices in patients with blood cancers.
- Trial name
- NCT03348826
- Testing
- Sodium Bicarbonate 8.4% Solution for Injection, Alteplase Injectable Solution
- Where
- Canada
- Sponsor
- University Health Network, Toronto
Central Line Complication
Incidence and Risk Factors of Central Line Catheter Related Thrombosis
Central venous catheters are frequently used for monitoring haemodynamic status and rapidly delivering fluid therapy during the peri- and postoperative periods.
- Trial name
- NCT03450785
- Testing
- ultrasound examination
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Hospital
Healthy
Medical Residents Performance: Effect of Simulation-Based Training
I Hypothesis: 1. Simulation-based training in maximal barrier precaution technique during central venous catheter (CVC) placement is superior to general videotape-based training 2.
- Trial name
- NCT00612131
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Catheterization, Peripheral
Study of Peripherally Inserted Central Catheter (PICC)-Related Infections in a Tropical Area
Septi-PICC study aims at assessing incidence of Peripherally Inserted Central Catheter (PICC)-related infections among patients managed in the University Hospital of La Reunion for PICC setting.
- Conditions
- Catheterization, Peripheral, Infection
- Trial name
- Septi-PICC (NCT02899546)
- Where
- France
- Volunteers
- 283 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Vascular Access Complication, Central Line Complication
Novel Strategy to Encourage Early Removal of Central Venous Catheters
The goal of this study is to determine if early placement of a midline catheter in patients with a central venous catheter (CVC) will decrease the number of days the CVC is in place.
- Conditions
- Vascular Access Complication, Central Line Complication, Central Line-Associated Infection, Superficial Vein Thrombosis
- Trial name
- NCT04136561
- Testing
- Midline catheter
- Where
- United States
- Sponsor
- Corewell Health East
Catheter Related Complications
Central Catheters Used for Chemotherapy in Women With Breast Cancer
The overall aim of this study is to evaluate two different central venous lines, PICC-lines (PICC) and subcutaneous venous access ports (SVAP) used for chemotherapy in women with breast cancer.
- Trial name
- PICC&PAC (NCT04324346)
- Testing
- FEC75 (or EC90) x 6, FEC100 + Taxotere (EC90 + Taxotere) 3+3, Paclitaxel
- Where
- Sweden
- Volunteers
- 250 people
- Sponsor
- Swedish Red Cross University College
Shock, Peripheral Venous Catheterization
Pulse Study: Peripheral Use of Low-dose Vasopressors for Safety and Efficacy in the Intensive Care Unit
Using medications to increase blood pressure, called vasopressors, is invaluable in treating patients who have difficulty maintaining stable blood pressure.
- Conditions
- Shock, Peripheral Venous Catheterization, Central Venous Catheterization, Critically Ill Patients Admitted in ICU
- Trial name
- PULSE (NCT06920173)
- Testing
- Experiemental: Peripheral Venous Catheter
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Kingston Health Sciences Centre
Ultrasound for Diagnosis of CVC Position in Children
Feasibility Study of CVC Diagnosis Via Ultrasound in Children
After the placement of a central venous catheter in children, a routine chest X-ray will be performed in order to examine the correct position of the catheter.
- Trial name
- CVC (NCT02178423)
- Testing
- Ultrasound for diagnosis of CVC position in children
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Medical University of Vienna
Pressure Injuries, Medical Device Related Pressure Ulcer (MDRPU)
Effect of Central Venous Catheter Dressing Types on Device-Related Pressure Injuries
The purpose of this clinical trial is to evaluate the effect of different central venous catheter dressing methods on the development of medical device-related pressure injuries in participants treated in the intensive care unit.
- Trial name
- CVC PROTECT (NCT07437040)
- Testing
- Gauze Dressing, Chlorhexidine Gluconate Transparent Dressing
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Catheter Thrombosis, Catheter-Related Infections
The Central Venous Catheter Related Complications in Critically Ill Patients
In this prospective clinical study, the researchers investigate the incidence of catheter-related thrombosis and catheter-related infection during indwelling central venous catheterization in critically ill patients, and analyzed…
- Conditions
- Catheter Thrombosis, Catheter-Related Infections, Central Venous Catheter Related Bloodstream Infection, Central Venous Catheter Thrombosis
- Trial name
- NCT03841240
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Zhujiang Hospital
Central Line-associated Bloodstream Infections
Impact of Disinfectant Caps on Nosocomial CLABSI
In a worldwide, one-day, prospective point-prevalence study, a prevalence of 15.1% for hospital-acquired central line-associated bloodstream infections (HA-CLABSI) was determined in 13,796 patients across 1,265 intensive care…
- Trial name
- NCT07430215
- Testing
- use of desinfection caps, sterile catheter cap
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- BDH-Klinik Hessisch Oldendorf
Cardiac Surgery, Shock
Hemoglobin Saturation in Superior Vena Cava and Right Atrium
The aim of the study is to compare oxygen saturation of blood samples collected from the superior vena cava, the right atrium, and the pulmonary artery.
- Trial name
- NCT01398436
- Testing
- central venous catheter positioning in right atrium
- Where
- Italy
- Volunteers
- 61 people
- Sponsor
- Catholic University of the Sacred Heart
Central Venous Catheter
Siting Central Venous Catheters Precisely While Performing the Access Procedure
For central venous catheters (CVC) to function properly, optimal tip location is of utmost importance. One technique to verify CVC position is the ECG method.
- Trial name
- NCT05751395
- Testing
- Central Venous Access
- Where
- 2 sites in Germany
- Volunteers
- 120 people
- Sponsor
- Deutsche Interdisziplinäre Vereinigung für Intensiv- und Notfallmedizin
Preterm, Pain, Acute
Peripheral Intravenous Central Catheter Intervention in Preterm Infants
This study will be conducted to evaluate the effect of grasping reflex stimulation applied during peripheral intravenous central catheter (PIC) intervention on pain and stress in preterm infants receiving treatment and care in…
- Conditions
- Preterm, Pain, Acute, Stress, Nursing Caries
- Trial name
- NCT05359809
- Testing
- Graspin Palmar Reflex Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Central Venous Catheter Thrombosis, Central Venous Catheter Associated Bloodstream Infection
t-PA Prophylaxis to Prevent Catheter-associated Thrombosis and Infection
The purpose of this pilot study is to test feasibility of concept, consent and enrollment rates, and mechanics of study designed to assess if intra-catheter dwells of tissue plasminogen activator (t-PA) is effective in decreasing…
- Trial name
- TOPCAT (NCT03672006)
- Testing
- alteplase (recombinant t-PA), Heparin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical College of Wisconsin