Clinical trials: Central Centrifugal Cicatricial Alopecia (CCCA)
Central Centrifugal Cicatricial Alopecia, Lichen Planopilaris
Safety and Biomarker Responses of Delgocitinib (JAK1,2,3/TYK2 Inhibitor) in Central Centrifugal Cicatricial Alopecia and Lichen Planopilaris
This study evaluates the safety, tolerability, and biomarker effects of twice-daily topical delgocitinib 2% cream in adults with lichen planopilaris (LPP) or central centrifugal cicatricial alopecia (CCCA) over a 48-week…
- Trial name
- NCT07487948
- Testing
- Delgocitinib
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Central Centrifugal Cicatricial Alopecia, Frontal Fibrosing Alopecia
Deucravacitinib in the Treatment of Cicatricial Alopecias
This is a prospective, open-label clinical trial, in which all participants will be treated with deucravacitinib for 48 weeks. Approximately 20 participants will be enrolled: 10 Central Centrifugal Cicatricial Alopecia (CCCA) and…
- Trial name
- NCT07508488
- Testing
- Deucravacitinib
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Central Centrifugal Cicatricial Alopecia
Azelaic Acid as a Novel Treatment for Central Centrifugal Cicatricial Alopecia (CCCA)
The purpose of this pilot study is to determine if azelaic acid shows potential to be an effective treatment for Central Centrifugal Cicatricial Alopecia (CCCA).
- Trial name
- (CCCA) (NCT05416333)
- Testing
- azelaic acid, usual medication for CCCA
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Wake Forest University Health Sciences
Central Centrifugal Cicatricial Alopecia (CCCA)
Treatment Results for Patients With Central Centrifugal Cicatricial Alopecia (CCCA): a Multicenter Prospective Study
The objective of this study is to examine photos of CCCA patients taken before and after treatment to compare treatment outcomes between different treatment groups
- Trial name
- CCCA (NCT04207931)
- Testing
- Topical steroid class I-II, Triamcinolone Acetonide, Doxycyline
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Wake Forest University Health Sciences
Scarring Alopecia, Central Centrifugal Cicatricial Alopecia
Barriers to Care and QOL for CCCA Patients
The purpose of the current project is twofold; first to determine what personal, historical, logistical, and environmental factors preclude women from obtaining medical care for CCCA hair loss.
- Conditions
- Scarring Alopecia, Central Centrifugal Cicatricial Alopecia, Central Centrifugal Scarring Alopecia
- Trial name
- NCT03044782
- Testing
- 53-Item Survey
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Central Centrifugal Cicatricial Alopecia
Calcipotriol as a Novel Treatment for Central Centrifugal Cicatricial Alopecia (CCCA)
The purpose of this pilot study is to determine if calcipotriol shows potential to be an effective treatment for Central Centrifugal Cicatricial Alopecia (CCCA).
- Trial name
- CCCA (NCT05416320)
- Testing
- Calcipotriol, Subject's already prescribed drug
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Central Centrifugal Cicatricial Alopecia
Effect of Platelet-Rich Plasma Versus Placebo in the Treatment of Central Centrifugal Cicatricial Alopecia
This study aims to investigate whether platelet-rich plasma (PRP) injections can help treat central centrifugal cicatricial alopecia (CCCA), a type of scarring hair loss that mostly affects women of African descent.
- Trial name
- NCT06998433
- Testing
- Platelet-Rich Plasma (PRP) Injections, Saline
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Baylor College of Medicine
Alopecia
Safety and Efficacy of Clobetasol Propionate 0.05% E Foam in Alopecia
The purpose of this study is to ascertain the safety and efficacy of Clobetasol Propionate 0.05% E Foam in the treatment of Central Centrifugal Cicatricial Alopecia.
- Trial name
- NCT01111981
- Testing
- Clobetasol Propionate 0.05% Emollient Foam
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Callender Center for Clinical Research
Fibrosing Alopecia, Frontal Fibrosing Alopecia
Follicular Revival in Fibrosing Alopecia: Evaluating Use of Micro-needling
To evaluate the efficacy microneedling via a professional tattoo machine in revitalizing hair follicles in patients with fibrosing alopecia.
- Conditions
- Fibrosing Alopecia, Frontal Fibrosing Alopecia, Central Centrifugal Cicatricial Alopecia
- Trial name
- NCT04342091
- Testing
- SOL Nova Device
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Yale University
Cicatricial Alopecia
Ritlecitinib for Cicatricial Alopecia
Alopecia could be subdivided into two main groups of diseases: non-scarring alopecia, such as male pattern baldness, or alopecia areata (AA), in which hair follicles are preserved, yet quiescent, and scarring alopecia, also known…
- Trial name
- NCT05549934
- Testing
- PF-06651600
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Emma Guttman
Central Centrifugal Cicatricial Alopecia
A Pilot Study of Revian Red All LED Cap as a Novel Treatment for Central Centrifugal Cicatricial Alopecia
Central centrifugal cicatricial alopecia (CCCA) is form of scarring hair loss that predominately affects middle-aged women of African descent.1 .
- Trial name
- NCT04764331
- Testing
- Revian Red All LED cap
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Wake Forest University Health Sciences
Central Centrifugal Cicatricial Alopecia (CCCA)
Tirzepatide for Treatment of CCCA
The goal of this pilot clinical trial is to learn if tirzepatide can treat active central centrifugal cicatricial alopecia (CCCA), a type of permanent scarring hair loss, in adults.
- Trial name
- NCT07734870
- Testing
- Tirzepatide
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Scarring Alopecia, Frontal Fibrosing Alopecia
Role of Neurogenic Inflammation and Topical 6% Gabapentin Therapy in Symptomatic Scarring Alopecia
This study will serve as a pilot study to determine the efficacy and safety of topical gabapentin in the treatment of symptomatic scarring alopecia.
- Conditions
- Scarring Alopecia, Frontal Fibrosing Alopecia, Lichen Planopilaris, Central Centrifugal Cicatricial Alopecia
- Trial name
- NCT03346668
- Testing
- Topical gabapentin
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Minnesota
Central Centrifugal Cicatricial Alopecia
Apremilast in the Treatment of Central Centrifugal Cicatricial Alopecia (CCCA)
This is a single-center, open-label clinical study to study the efficacy of apremilast in the treatment of mild to moderate central centrifugal cicatricial alopecia.
- Trial name
- NCT03521687
- Testing
- Apremilast
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Central Centrifugal Cicatricial Alopecia
Baricitinib for Central Centrifugal Cicatricial Alopecia in Adults of African Descent
This study evaluated the safety and efficacy of baricitinib 4 mg daily in adults of African descent with biopsy-proven central centrifugal cicatricial alopecia, a scarring alopecia for which no FDA-approved treatment exists.
- Trial name
- NCT07843732
- Testing
- Baricitinib
- Where
- 4 sites in United States
- Volunteers
- 27 people
- Sponsor
- Raven Clinical Research
Central Centrifugal Cicatricial Alopecia
A Study of Revian Red All LED Cap as a Novel Treatment for Central Centrifugal Cicatricial Alopecia
The purpose of this study is to determine if the Revian Red All LED cap shows potential to be an effective treatment for Central centrifugal cicatricial alopecia (CCCA) by recruiting hair follicles back to anagen growth or by…
- Trial name
- NCT05759338
- Testing
- Revian Red All LED cap
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Wake Forest University Health Sciences
Central Centrifugal Cicatricial Alopecia (CCCA)
Study to Determine Effect of Gentle Wounding to Stimulate Hair Follicle Neogenesis
The investigators have extensive evidence in mouse that wounding leads to the generation of new hair follicles in the skin. This can be an important new therapy for patients with scarring, but especially those with alopecia.
- Trial name
- NCT03491267
- Testing
- Retinoic acid, Laser
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Johns Hopkins University