Clinical trials: Central Auditory Disease
Retrocochlear Pathology, Auditory Processing Disorder, Central
Cochlear Implantation in Single Sided Deafness and Asymmetrical Hearing Loss: a Cost/Utility Study.
The investigators assume that cochlear implants in this indication are not only effective but also cost-effective. The investigators' experimental protocol relies on real life therapeutic strategy, where a cochlear implant may be…
- Conditions
- Retrocochlear Pathology, Auditory Processing Disorder, Central, Major Cochlear Ossification or Malformation
- Trial name
- CISSD (NCT02204618)
- Testing
- cochlear implantation, 6 months initial abstention
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Toulouse
Parkinson Disease, Gait, Unsteady
Effect of Haptic Cueing on Long-Range Autocorrelations in Parkinson's Disease Gait Variability
Parkinson's Disease (PD) patients suffer from gait impairments responsible for falls and bad quality of life: reduced speed and stride length, randomness in the temporal organization of stride duration variability (reduced…
- Trial name
- NCT05790759
- Testing
- No cueing versus Haptic cueing versus Auditory cueing during parkinson's disease gait
- Where
- 2 sites in Belgium
- Volunteers
- 10 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Siderosis, Neurological Disorder
Audiovestibular Function in Infratentorial Superficial Siderosis
One in six people in the United Kingdom and over 400 million people worldwide have disabling hearing loss. This figure will double by 2050 as predicted by the World Health Organisation.
- Conditions
- Siderosis, Neurological Disorder, Rare Diseases, Age Related Hearing Loss
- Trial name
- AViSS (NCT04200664)
- Testing
- Hearing assessment, Vestibular/balance assessment, Quality of life assessment
- Where
- 2 sites in United Kingdom
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University College, London
Parkinson's Disease
Monitoring Brain Waves in Response to Visual and/or Auditory Stimulation in Parkinson's Disease Patients
Voltage fluctuation as a result of brain activity will be recorded into the computer using an EEG device.
- Trial name
- NCT02768896
- Testing
- Baseline, visual stimuli, Auditory stimuli
- Volunteers
- 100 people
- Sponsor
- Rambam Health Care Campus
Parkinson's Disease
Effects of RAC With Locomotion Training on Cortical Excitability and Behavior in Patients With PD
In this study, 51 subjects include 17 freezers,17 non-freezers and 17 aged-matched healthy subjects will be recruited. We will compare the cortical excitability, gait performance, and stepping-in-place performance before and…
- Trial name
- NCT03656796
- Testing
- Treadmill training with auditory cues, Treadmill training without auditory cues
- Where
- Taiwan
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Progesterone, Estrogens
Neural Changes in the Aging Auditory System
The purpose of this study was to determine the effects of hormone replacement therapy (HRT) on hearing in post-menopausal women.
- Conditions
- Progesterone, Estrogens, Hearing, Psychoacoustics
- Trial name
- NCT00264407
- Testing
- Hormone Replacement Therapy - HRT
- Where
- 2 sites in United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Stroke, Gait, Hemiplegic
Effect of RAS on Balance and Gait After Stroke
A rhythmic auditory stimulation intervention may be beneficial in order to improve movement parameters after stroke. Reviews argue that more randomized controlled trials with a control group are needed.
- Conditions
- Stroke, Gait, Hemiplegic, Gait Disorders, Neurologic
- Trial name
- NCT03974490
- Testing
- Rhythmic auditory stimulation
- Where
- Spain
- Volunteers
- 55 people
- Sponsor
- Hospital Sociosanitari Mutuam Girona
Age-related Hearing Loss, Dementia
Management of Age-Related Auditory Decline and Early Warning of Its Co-occurring Dementia
Against the backdrop of global population aging, age-related hearing loss (ARHL) has reached epidemic proportions and is increasingly recognized as an independent risk factor for cognitive decline and other major…
- Trial name
- AHEAD (NCT07608640)
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Neuromyelitis Optica Spectrum Disorder
Acceptability and Safety of MR-C-014 in Persons With Neuromyelitis Optica Spectrum Disorder
The purpose of this proof of concept study is to assess the acceptability and safety of MR-C-014 in persons with Neuromyelitis optica spectrum disorder (NMOSD) who have a gait deficit.
- Trial name
- aNiMatO (NCT06374264)
- Testing
- MR-C-014
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- MedRhythms, Inc.
Auditory Perceptual Disorders, Aging Problems
Neuroplasticity in Auditory Aging_Project 2 Aims 1 and 2
Millions of elderly adults in the USA have age related hearing loss (ARHL), a malady that affects half of adults 60-69 years, and the majority of older adults.
- Trial name
- NCT03475043
- Testing
- Auditory training: temporal cues
- Where
- United States
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Profound Hearing Impairment
Positron Emission Tomography Imaging of Brain Reorganisation of the Central Auditory Cortex in Asymetrical Profound Deaf Patient With a Cochlear Implantation.
Our main objective is to study how the extent of reorganization of the central auditory system is related to the binaural integration in cochlear implanted subjects with asymmetric hearing loss.
- Trial name
- UniTEP (NCT03117413)
- Testing
- Positron emission tomography scan
- Where
- 2 sites in France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Gamma Oscillations, Healthy Adults
Investigating the Effectiveness of Personalized Optimal Gamma Auditory Frequency Stimulation Intervention on Cognitive Function Enhancement
This study aims to evaluate whether personalized gamma-frequency auditory stimulation enhances cognitive function and brain synchronization.
- Conditions
- Gamma Oscillations, Healthy Adults, Alzheimer's Disease (AD), Gamma Entrainment Using Sensory Stimuli (GENUS)
- Trial name
- NCT07690865
- Testing
- Personalized optimal gamma auditory frequency stimulation, Non-optimal gamma auditory frequency stimulation
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Stroke
Gait Training for Hemiplegic Stroke Patients With Stationary Trainer
This study aims to evaluate the effectiveness of a novel mobile neurodevelopmental treatment (NDT) gait training device for patients recovering from stroke.
- Trial name
- NCT07395544
- Testing
- NDT Gait Training System
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Cheng-Hsin General Hospital
Auditory Perceptual Disorders, Stress Disorder
The Listening Project at the ADD Centre and Biofeedback Institute of Toronto
Purpose: A research project will be conducted at the ADD ("Attention Deficit Disorder") Centre and Biofeedback Institute of Toronto to evaluate the feasibility of the Listening Project Protocol (LPP) intervention in individuals…
- Trial name
- NCT02680730
- Testing
- Listening Project Protocol
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of North Carolina, Chapel Hill
Rehabilitation, Parkinson Disease
Golden Walk as Measure of Gait Rehabilitation in Parkinson's Disease
Gait is specifically impaired in Parkinson's disease (PD). External auditory cue based on a binary rhythm tested in PD patients disappear when the stimulus is removed.
- Conditions
- Rehabilitation, Parkinson Disease, Locomotion Disorder, Neurologic, Rhythm; Abnormal
- Trial name
- NCT04706572
- Testing
- Stimulation with external auditory bio-feedback
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Cognitive Dysfunction, Auditory Dysfunction, Central
Effect of Propfol Versus Sevoflurane on Auditory and Cognitive Function
Perioperative hearing loss is a rarely reported phenomenon. However, it occurs more frequently than most anaesthesiologists suspect.
- Trial name
- NCT04874545
- Testing
- Propofol
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Beni-Suef University
Healthy, Mild Cognitive Impairment
Does Acoustic Stimulation During Sleep Boost Slow Wave Sleep and Memory Performance?
With aging the amount of slow wave sleep decreases drastically and this disruption is markedly exaggerated in older adults suffering from mild cognitive impairment and Alzheimer's disease.
- Conditions
- Healthy, Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- NCT04277104
- Testing
- Closed loop acoustic stimulation
- Where
- Switzerland
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Bern
Central Auditory Processing Disorder, Traumatic Brain Injury
Central Auditory Processing Disorders Associated With Blast Exposure
The incidence of central auditory dysfunction in war fighters who are exposed to high-explosive blasts while serving in combat have not been clearly determined.
- Conditions
- Central Auditory Processing Disorder, Traumatic Brain Injury, Hearing Loss
- Trial name
- NCT00554801
- Testing
- Audiological testing
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Auditory Processing Disorder, Central, Stroke
Auditory Rehabilitation in Stroke Patients With Auditory Processing Disorders
This study aimed to evaluate long term benefits in speech reception in noise, after daily 10 week use of an assisting listening device (personal frequency-modulates systems) , in non-aphasic stroke patients with auditory…
- Trial name
- NCT02889107
- Testing
- personal frequency modulated systems
- Where
- United Kingdom
- Volunteers
- 9 people
- Sponsor
- University College, London
Cerebral Palsy
Effect of Rhythmic Auditory Stimulation on Balance in Children With Cerebral Palsy.
To evaluate the effect of Rhythmic Auditory Stimulation (RAS) on balance in children with cerebral palsy.
- Trial name
- NCT05455970
- Testing
- Rhythmic auditory stimulation (RAS)
- Where
- Thailand
- Volunteers
- 22 people
- Sponsor
- Mahidol University