Clinical trials: Catheter-associated Bloodstream Infections (CLABSI)
CLABSI - Central Line Associated Bloodstream Infection
Risk Factors for PICC-Related Infection in 994 High-Risk Patients: The Role of Hb Levels and Sampling Frequency
This retrospective cohort study aims to evaluate the incidence and clinical predictors of Central Line-Associated Bloodstream Infections (CLABSI) in patients receiving Peripherally Inserted Central Catheters (PICCs) via the…
- Trial name
- NCT07674992
- Testing
- Hemoglobin level
- Where
- Thailand
- Volunteers
- 1,239 people
- Sponsor
- Mahidol University
Intensive Care (ICU), Central Venous Catheter Related Infections
Impact of Infusion Line Change Frequency on Infectious Complications Related to Central Venous Catheters in the ICU - A Randomized Controlled Trial
In the intensive care unit, patients' care and secure drugs administration require a central venous catheter. These invasive devices can lead to complications, particularly infections.
- Conditions
- Intensive Care (ICU), Central Venous Catheter Related Infections, Critical Care Nursing, Catheter-associated Bloodstream Infections (CLABSI)
- Trial name
- TANDOORI (NCT07183592)
- Testing
- 7-day Infusion set replacement, 4-day infusion set replacement
- Where
- 27 sites in France
- Volunteers
- 2,830 people
- Sponsor
- University Hospital, Angers
CLABSI - Central Line Associated Bloodstream Infection, CRBSI - Catheter Related Bloodstream Infection
Neonatal Catheter Lock for Infection Prevention
For newborns admitted to Neonatal Intensive Care Units (NICUs), one of the main risk factors for late-onset sepsis is the presence of a central venous catheter (CVC), which is often essential for the administration of medications…
- Conditions
- CLABSI - Central Line Associated Bloodstream Infection, CRBSI - Catheter Related Bloodstream Infection, Neonatal Sepsis, Late-Onset
- Trial name
- Neo-CLIP (NCT07585188)
- Testing
- Taurolidine 2% lock, Normal saline lock
- Where
- Italy
- Volunteers
- 576 people
- Sponsor
- University of Turin, Italy
Falls Injury, Readmission Rates
Duke Virtual IntEgrated Workflow
This quality improvement initiative aims to evaluate the implementation, utilization, and impact of virtual care technologies and workflows being implemented at Duke University Health System (DUHS).
- Conditions
- Falls Injury, Readmission Rates, CLABSI - Central Line Associated Bloodstream Infection, Catheter Associated Urinary Tract Infection
- Trial name
- Duke VIEW (NCT07406074)
- Testing
- Co-Care
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Duke University
CRBSI - Catheter Related Bloodstream Infection, Evidence-based Nursing Practice
Multicenter Clinical Translational Study of "ICU-NO CRBSI" Based on Improvement Science
The goal of this type of study is to construct the continuous quality promotion project "ICU-NO CRBSI(Catheter-Related Bloodstream Infection , CRBSI)" based on improvement science, and to verify its effect in the prevention of…
- Conditions
- CRBSI - Catheter Related Bloodstream Infection, Evidence-based Nursing Practice, Central Venous Catheter Related Bloodstream Infection, Central Venous Catheter Associated Bloodstream Infection
- Trial name
- NCT06085690
- Testing
- evidence-based intervention Plan for the Prevention of CRBSI in ICU patients
- Where
- China
- Volunteers
- 8,050 people, healthy volunteers welcome
- Sponsor
- Fudan University
Peripherally Inserted Central Catheter, Umbilical Venous Catheter
Umbilical Venous Versus Peripherally Inserted Central Catheters in Neonates: A Prospective Cohort Study of Complications, Catheter Survival, and CLABSI"
This study aims to prospectively compare umbilical venous catheters (UVCs) and peripherally inserted central catheters (PICCs) in neonates, focusing on complications, catheter survival, and central line-associated bloodstream…
- Conditions
- Peripherally Inserted Central Catheter, Umbilical Venous Catheter, CLABSI - Central Line Associated Bloodstream Infection
- Trial name
- NCT07209670
- Testing
- peripherally inserted central catheter insertion, umbilical venous catheters insertion
- Volunteers
- 360 people
- Sponsor
- Assiut University
CLABSI - Central Line Associated Bloodstream Infection, Catheter-Related Blood Stream Infection
Study on the Reduction of Catheter-related Infections by Use of Self-disinfecting Venous and Arterial Access Caps
Observational study on the reduction of catheter-related Infections by use of self-disinfecting venous and arterial access caps (Curos caps ;3M, Saint Paul, MN, USA)
- Trial name
- STERILE (NCT04534348)
- Testing
- 70% isopropyl alcohol-impregnated catheter caps
- Where
- Germany
- Volunteers
- 598 people
- Sponsor
- University of Cologne
Central Venous Catheter Thrombosis, Central Venous Catheter Related Bloodstream Infection
CLiCK in the Critical Care Unit
Insertion of a central venous access device (CVAD) allows clinicians to easily access the circulation of a patient to administer life-saving interventions.
- Conditions
- Central Venous Catheter Thrombosis, Central Venous Catheter Related Bloodstream Infection, Catheter Complications, Catheter Blockage
- Trial name
- CLiCK (NCT04548713)
- Testing
- 4% EDTA, Saline
- Where
- 6 sites in Canada
- Volunteers
- 1,449 people
- Sponsor
- Fraser Health
Health Care Associated Infection, Ventilator Associated Pneumonia
Daily Chlorexidine Bath for Health Care Associated Infection Prevention
Cluster randomized controlled trial comparing two bathing strategies in critically ill patients. The intervention group will receive daily bathing with chlorhexidine. The control group will receive usual care.
- Conditions
- Health Care Associated Infection, Ventilator Associated Pneumonia, Central Line-associated Bloodstream Infection (CLABSI), Catheter-Associated Urinary Tract Infection
- Trial name
- CLEAN-IT (NCT05485051)
- Testing
- 2% chlorhexidine digluconate solution with surface-active agents, Usual Baths
- Where
- 16 sites in Brazil
- Volunteers
- 15,730 people
- Sponsor
- Hospital do Coracao
CLABSI - Central Line Associated Bloodstream Infection, Deep Vein Thrombosis
Tunneled Peripherally Inserted Central Catheter (PICC) in Adult Patients and Associated Outcomes
The aim of this multicenter randomized clinical trial is to compare the tunneling technique of PICC insertion with the non-tunneled insertion technique in the incidence of the combined or isolated outcome of catheter-related…
- Conditions
- CLABSI - Central Line Associated Bloodstream Infection, Deep Vein Thrombosis, Dislodged Catheter, Occlusion
- Trial name
- NCT06365528
- Testing
- Subcutaneous tunnelling, Non-tunnelling
- Where
- Brazil
- Volunteers
- 840 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Central Line-associated Bloodstream Infection (CLABSI), Central Venous Catheter Associated Bloodstream Infection
Central Venous Catheter Insertion Site and Colonization in Pediatric Cardiac Surgery
Randomized controlled trial comparing femoral vs internal jugular insertion site of central venous catheters (CVC) in newborns and infants undergoing cardiac surgery.
- Conditions
- Central Line-associated Bloodstream Infection (CLABSI), Central Venous Catheter Associated Bloodstream Infection, Heart; Surgery, Heart, Functional Disturbance as Result, Congenital Heart Disease
- Trial name
- PRECiSE (NCT03282292)
- Testing
- Internal jugular vein CVC insertion
- Where
- Italy
- Sponsor
- IRCCS Policlinico S. Donato
CLABSI - Central Line Associated Bloodstream Infection, CRBSI - Catheter Related Bloodstream Infection
Erythema at Exit Site & Tablet Camera
Background: In critical care medicine central venous catheters play an important role in the source of infections. In the daily routine prior to the diagnosis the suspicion of catheter related infection is discussed in the…
- Conditions
- CLABSI - Central Line Associated Bloodstream Infection, CRBSI - Catheter Related Bloodstream Infection, Digital Technology
- Trial name
- NCT04927325
- Testing
- Set of Photos
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Medical University of Vienna
Central Line-associated Bloodstream Infection (CLABSI), Catheter-related Bloodstream Infection
Effect of Vancomycin After Catheter Replacement
Randomized controlled trial of the effect of a single-dose intravenous Vancomycin after catheter replacement for suspected central line-associated bloodstream infection on resolution of infection in critically ill patients.
- Trial name
- VanCat (NCT04856878)
- Testing
- Vancomycin
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Catheter-associated Bloodstream Infections (CLABSI)
Catheter Biofilm Microbiome in Infected Neonatal Catheters.
Percutaneously Inserted Central Catheters (PICCs) are special tubes that are inserted into blood vessels of premature babies (neonates) to give them nutrition and medications.
- Trial name
- NCT01985737
- Testing
- Sample collection
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Baylor College of Medicine
Infection, Catheter-Related, Central Line-associated Bloodstream Infection (CLABSI)
Ethanol-lock Therapy for the Prevention of Non-tunneled Catheter-related Infection in Pediatric Patients
Central venous catheter (CVC) infection is a common complication in pediatric patients, resulting in prolonged length of stay in hospital, requiring antibiotics, invasive procedures and increase morbidity and mortality.
- Conditions
- Infection, Catheter-Related, Central Line-associated Bloodstream Infection (CLABSI), Pediatric
- Trial name
- E-LockPed (NCT03253887)
- Testing
- Ethanol-lock
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Central Line-Associated Bloodstream Infection (CLABSI), Venous Thromboembolism
Patient Safety Learning Laboratory: Making Acute Care More Patient-Centered
The Brigham and Women's Hospital (BWH) Patient Safety Learning Laboratory (PSLL) focuses on developing health information technology (HIT) tools to engage patients, family, and professional care team members in reliable…
- Conditions
- Central Line-Associated Bloodstream Infection (CLABSI), Venous Thromboembolism, Patient Fall, Catheter-Associated Infection
- Trial name
- PSLL (NCT02969343)
- Testing
- Patient Safety health information technology
- Where
- United States
- Volunteers
- 21,000 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital