Clinical trials: Cataract and IOL Surgery, active
IOL, Cataract
Post-Market Clinical Follow-Up Study on the Rotational Stability of an Intraocular Lens After Cataract Surgery
The goal of this post-market, prospective study at multiple clinics is to evaluate the rotational stability of the RayOne Model RAO800S non-toric monofocal intraocular lens with orientation marks in adult patients undergoing…
- Trial name
- NCT07099079
- Volunteers
- 92 people
- Sponsor
- Rayner Intraocular Lenses Limited
Dry Eye Disease (DED), Cataract
Impact of DED on the Accuracy of Preoperative Keratometry Values in the Calculation of IOL Power for Cataract Surgery.
This study looks at how dry eye disease can affect important eye measurements needed before cataract surgery. These measurements guide us in choosing the right artificial lens to implant, which is essential for achieving clear…
- Trial name
- NCT06989827
- Testing
- Preservative free artificial tear
- Where
- Croatia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Sestre Milosrdnice
Cataract, Multifocal Intraocular Lens
Visual Outcomes in Patients Contralaterally Implanted With PanOptix Pro and Clareon Vivity Compared to Bilateral Implantation of PanOptix Pro
Title: Visual Outcomes in Patients Contralaterally Implanted with PanOptix Pro and Clareon Vivity Compared to Bilateral Implantation of PanOptix Pro Sponsor: Brian Shafer, MD, Shafer Vision Institute Objective: To compare visual…
- Trial name
- NCT07076277
- Testing
- Clareon PanOptix Pro and Clareon Vivity Intraocular Lens, Clareon PanOptix Pro Intraocular Lenses
- Where
- 5 sites in United States
- Volunteers
- 346 people
- Sponsor
- Brian Shafer
Cataract and IOL Surgery, IOL Implantation
Head-to-Head Comparison of Five Enhanced Depth of Focus IOLs and One Monofocal IOL
Study Goal The goal of this clinical trial is to compare how well four different types of artificial lenses (called intraocular lenses or IOLs) help people see after cataract surgery.
- Conditions
- Cataract and IOL Surgery, IOL Implantation, Presbyopia Correction, Extended Depth of Focus
- Trial name
- AKA-Reports (NCT07051720)
- Testing
- Bilateral implantation of CT ASPHINA 409M, Bilateral implantation of TECNIS Eyhance ICB00, Bilateral implantation of AcrySof® IQ Vivity®
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- Augenklinik Ahaus G + H GmbH & Co. KG
Irregular Astigmatism, Astigmatism
Improving Visual Quality in Patients With Irregular Corneas Using Asymmetrical Toric Intraocular Lenses
Cataract surgery in patients with irregular corneas presents unique challenges, primarily due to the high variability in keratometry and corneal tomography measurements, which complicates accurate intraocular lens (IOL)…
- Conditions
- Irregular Astigmatism, Astigmatism, Cataract and IOL Surgery
- Trial name
- VITAL (NCT07294716)
- Testing
- AMILens Individual
- Where
- Austria
- Volunteers
- 15 people
- Sponsor
- Johannes Kepler University of Linz
Cataract, Fuchs Endothelial Corneal Dystrophy
Partial Range Of Field IOLs in DMEK-Enabled Procedures
Study Overview This study aims to evaluate the visual outcomes, quality of vision, and patient satisfaction after receiving an extended range PRoF intraocular lens (IOL) during triple Descemet Membrane Endothelial Keratoplasty…
- Trial name
- PROFIDE (NCT07441616)
- Testing
- combined cataract and lamellar endothelial keratoplasty
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Universitair Ziekenhuis Brussel
Cataract
Visual Performance of Clareon Vivity and PureSee IOL
This is study to determine the visual performance of patients with age-related cataracts implanted in both eyes with either of two extended depth of focus intraocular lenses, the Clareon Vivity (Alcon Healthcare) or the PureSee…
- Trial name
- PURVI2 (NCT07165197)
- Testing
- Phacoemulsification with implantation of an extended depth of focus intraocular lens
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- OMIQ Research
Cataract and IOL Surgery, Cataract Surgery Anesthesia
The Impact of Physiologic Cataract Surgery on Patient Comfort and Medication Usage
The study will pertain to investigating the impact of high vs low IOP on the intraoperative experience and comfort for the patient and surgeon.
- Conditions
- Cataract and IOL Surgery, Cataract Surgery Anesthesia, Cataract Surgery Experience, Nuclear Cataract
- Trial name
- NCT07223866
- Testing
- High IOP Setting, Low IOP Setting
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Matthew Rauen
Cataract
Visual and Patient Reported Outcomes With Clareon TruPlus
This is a prospective, single-site, two-surgeon, single-arm, observational study evaluating the Clareon TruPlus IOL. Subjects will be assessed up to 3 months post-operatively.
- Trial name
- NCT07648355
- Testing
- Clareon TruPlus
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- OVO LASIK + Lens
Dry Eye
SAS 1: Develop Ocular Disease (OSD) Diagnostic, Algorithms, and Management Protocols for Cataract Surgery
Patient: Tear film issues resulting in poor visual outcomes are a major cause of dissatisfaction after cataract surgery. There is no universal best preoperative algorithm for managing the ocular surface prior to surgery.
- Trial name
- NCT07323264
- Where
- Singapore
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Louis Tong
Cataract and IOL Surgery, Epi-retinal Membrane
Outcomes of Combined Cataract Surgery With Retinal Surgery for Visually Significant Epiretinal Membrane With Vivity Versus Monofocal Intraocular Lens
To investigate the patient Quality of Life and satisfaction outcomes of combined cataract surgery with retinal surgery for visually significant epiretinal membrane in patients receiving Vivity IOL versus standard monofocal…
- Trial name
- NCT07070492
- Testing
- cataract surgery, retinal surgery
- Volunteers
- 36 people
- Sponsor
- Debbie Kuo, MD
Eye Disorders, Cataract Extraction
Effectiveness of a Large Language Model-Based Educational Tool on Intraocular Lens Options
Patients with cataracts disease need to choose what type of artificial lens will go into their eye prior to surgery date. Some lenses are standard and are usually covered by insurance.
- Conditions
- Eye Disorders, Cataract Extraction, Cataract and IOL Surgery, Cataract Surgery Experience
- Trial name
- NCT07317661
- Testing
- LLM-based Education
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Stanford University
Pediatric Cataract, IOL Implantation
Myopia Progression Control Using Atropine 0.05% After Pediatric Cataract Surgery And Intraocular Lens Implantation Surgery
Myopic shift remains a debilitating and unpredictable adverse event following pediatric cataract surgery. While research exploring peripheral myopic defocus for post-cataract surgery myopia prevention shows promising results, the…
- Conditions
- Pediatric Cataract, IOL Implantation, Myopia Progression
- Trial name
- NCT07364370
- Testing
- Atropine Eye drops
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Cataract and IOL Surgery
Development of Optical Biometer
The Helioscope (Cassini Technologies B.V.) is a novel device under development that aims at combining LED-based corneal topography and SS-OCT to provide accurate and fast measurements of both the corneal shape and the ocular…
- Trial name
- CH-0203 (NCT07325162)
- Testing
- New Investigational Optical Biometer (Device), Comparator Device A (Cassini Ambient), omparator Device B (Argos)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Cassini Technologies
Endothelial Cell Loss, Corneal, Cataract and Intraocular Lens (IOL) Surgery
Effect of Vitamin C Supplementation in Corneal Endothelial Damage in Phacoemulsification of Patients with Hard Cataracts
The goal of this clinical trial is to analyze the protective effects of oral ascorbic acid on the corneal endothelial layer undergoing oxidative stress due to phacoemulsification in patients with hard cataracts.
- Trial name
- NCT06781970
- Testing
- Oral Vitamin C
- Where
- 2 sites in Indonesia
- Volunteers
- 120 people
- Sponsor
- Universitas Indonesia
Cataract and IOL Surgery, Keratoplasty
Postoperative Outcomes of a Toric AddOn Intraocular Lens After Keratoplasty and Cataract Surgery
The aim of this clinical study is to evaluate a toric add-on intraocular lens (IOL) for the correction of high astigmatism in patients who have undergone keratoplasty and cataract surgery.
- Conditions
- Cataract and IOL Surgery, Keratoplasty, Toric Intraocular Lens Stability
- Trial name
- AddOn (NCT07452042)
- Testing
- AddOn toric IOL implantation
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Vienna
Cataract, Cataract Surgery
Binocular and Monocular Distance-Corrected Visual Performance and Defocus Characteristics of Clareon Truplus Intraocular Lens (IOL)
This study aims to generate data that characterizes visual outcomes, including the binocular distance-corrected intermediate visual acuity (DCIVA) at 66cm or defocus behavior, of the Clareon TruPlus modified monofocal intraocular…
- Conditions
- Cataract, Cataract Surgery, Cataract Bilateral, Cataract (Post-operative Cataract Surgery Follow-up)
- Trial name
- BMVDI (NCT07589894)
- Testing
- Clareon TruPlus IOL
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Colvard Kandavel Eye Center
Cataract
AI-Driven IOL Prediction Using SS-OCT Biometry
This prospective, multicenter, non-interventional observational study aims to evaluate the agreement between a novel swept-source optical coherence tomography (SS-OCT) biometer and the IOLMaster 700 for ocular biometric…
- Trial name
- NCT07733154
- Testing
- IOLMaster 700, Novel SS-OCT Biometer
- Where
- 3 sites in Australia, China and 1 more
- Volunteers
- 2,500 people
- Sponsor
- The Hong Kong Polytechnic University
Age Related Cataracts
Visual Performance of Clareon PanOptix vs. a Comparable Multifocal Intraocular Lens
This is a two-part, multi-center, investigator-initiated clinical study comparing visual outcomes and patient satisfaction in subjects receiving bilateral implantation of either the Clareon PanOptix intraocular lens (IOL) or a…
- Trial name
- NCT07006428
- Testing
- Clareon PanOptix or PanOptix Toric IOLs, Comparable multifocal IOL
- Where
- 3 sites in United States
- Volunteers
- 290 people
- Sponsor
- Argus Research Center, Inc.
Cataract
Outcomes of Clareon PanOptix Pro in Patients With Prior Myopic Refractive Surgery
This study is a Single center, single arm, prospective, observational study of clinical outcomes following bilateral cataract surgery and Clareon PanOptix Pro implantation.
- Trial name
- NCT06555289
- Testing
- Clareon PanOptix Pro IOL
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Juliette Eye Institute Research Center