Clinical trials: Cat Allergy, active
Allergy
LYmph Node eXamination in Cat Allergen Immunotherapy
Sixteen eligible cat-allergic participants will be accrued in the study. Eight participants who have been on subcutaneous immunotherapy (SCIT) at maintenance dosing for at least 1 year will be assigned to the SCIT cohort, and 8…
- Trial name
- LYNX (NCT07447869)
- Testing
- Intradermal cat allergen challenge
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Allergy to Cats
Crossover Study of Zafirlukast in Preventing Allergen-induced Signs and Symptoms in Response to Cat Dander Challenge
The goal of this clinical trial is to test the hypothesis that pre-treatment with a nasal dose of Zafirlukast works well in blocking the signs and symptoms of cat dander in patients sensitive to cat dander.
- Trial name
- NCT06069063
- Testing
- Zafirlukast
- Volunteers
- 12 people
- Sponsor
- Allergy & Asthma Medical Group & Research Center
Asthma, Allergic Rhinitis
Viral Mucosal Reprogramming
This is a mechanistic, controlled, open-label, single-site study to evaluate the effects of RG-RV16 inoculation on airway mucosal gene expression and airway remodeling in 25 healthy controls (HC), in 25 allergic rhinitis subjects…
- Conditions
- Asthma, Allergic Rhinitis, Cat Allergy, Healthy
- Trial name
- VMR (NCT05331170)
- Testing
- Research Grade RG-RV
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Allergic Conjunctivitis
A Study to Evaluate the Efficacy and Safety of Fel d 1 Monoclonal Antibodies in Adult and Pediatric Participants With Allergic Conjunctivitis Due to Cat Allergy
This study is researching two experimental medicines, freneslerbart and mevonlerbart. Freneslerbart and mevonlerbart can be given alone or together. When given together, the medicine is called "REGN-2Cat".
- Trial name
- NCT07675811
- Testing
- REGN-2Cat, Freneslerbart, Mevonlerbart
- Where
- 2 sites in United States
- Volunteers
- 570 people
- Sponsor
- Regeneron Pharmaceuticals
Allergic Rhinitis
Allergenic Extract Standardized Cat Hair AP in an Allergic Rhinitis Model.
The goal of this study is to learn if a cat allergen extract known as Allergenic Extract Standardized Cat Hair Acetone Precipitated (AP Cat) can induce allergic rhinitis (AR) in a nasal allergen challenge model in cat-allergic…
- Trial name
- AP-CAT (NCT06828484)
- Testing
- Allergenic Extract Standardized Cat Hair Acetone-Precipitated (AP)
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Queen's University
Cat Allergy (Disorder), Allergic Rhinitis
A Study on the Efficacy of Environmental Probiotics in Patients With Cat Hair Allergies
Objective of this clinical trial: The goal of this clinical study is to evaluate whether an environmental probiotic spray can improve symptoms in adults with cat allergy-induced allergic rhinitis (AR) and allergic asthma (AA).
- Conditions
- Cat Allergy (Disorder), Allergic Rhinitis, Allergic Asthma
- Trial name
- NCT07114133
- Testing
- Environmental Probiotic Spray Intervention
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Conjunctivitis Allergic
A Study to Identify and Characterize Adults and Pediatric Participants With Cat and/or Birch Allergy
The purpose of this Patient Identification and Characterization (PIC) study is to collect information and perform limited allergy-related procedures to determine if participants can qualify for cat and/or birch tree pollen…
- Trial name
- NCT07710846
- Testing
- Noninterventional
- Volunteers
- 1,500 people
- Sponsor
- Regeneron Pharmaceuticals
Allergic Rhinitis, Allergic Asthma
Safety and Immunogenicity of Cat-allergen Intralymphatic Immunotherapy in Patients With Cat Allergy With and Without Asthma
The goal of this clinical trial is to evaluate the safety and tolerability of intralymphatic immunotherapy (ILIT) with ALUTARD SQ Felis domesticus in patients with cat allergy-induced allergic rhinitis and asthma.
- Trial name
- NCT06960382
- Testing
- ALUTARD SQ® Felis domesticus
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- University of Zurich
Allergic Rhinitis
Impact of Pet Cats on Nasal and Gut Microbiota in Patients With Cat Allergen Allergy
It has been reported that the incidence of allergic rhinitis (AR) is as high as 24.1% in adults and 16.8% in children in China. A study explored the changes in the incidence of AR in China, and the study showed that the incidence…
- Trial name
- NCT07110311
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University