Clinical trials: Carpal Tunnel Release
Carpal Tunnel Syndrome, Median Neuropathy
Hydrodissection With Neuroprolotherapy Versus Open Release for Carpal Tunnel Syndrome
This study is a randomized controlled, parallel-group, non-inferiority trial designed to compare ultrasound-guided hydrodissection combined with neuroprolotherapy versus open carpal tunnel release in patients with carpal tunnel…
- Trial name
- HN-CTS (NCT07576803)
- Testing
- Ultrasound-guided Hydrodissection of the Median Nerve, Open Carpal Tunnel Release
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- Universidade Federal de Pernambuco
Carpal Tunnel Syndrome (CTS)
Simultaneous vs. Postponed Carpal Tunnel Release (CTR) During Distal Radius Fracture (DRF) Fixation.
This randomized study evaluates the impact of performing a prophylactic carpal tunnel release (CTR) at the same time as surgical fixation for a distal radius fracture (DRF).
- Trial name
- NCT07509437
- Testing
- Carpal tunnel release, Distal Radius Fracture Fixation with Observation.
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Benha University
Carpal Tunnel Syndrome, Wound Infection
abSorbable vErsus Non-absorbable SuturEs for Wound Closure in Carpal Tunnel Release
Carpal Tunnel Syndrome is a prevalent condition, up to 9% in women and 0.6% in men. Surgical decompression in the most effective treatment. After surgery, approximately 1,8% of the patients develop a wound infection.
- Conditions
- Carpal Tunnel Syndrome, Wound Infection, Suture, Complication
- Trial name
- SENSE (NCT05431101)
- Testing
- Carpal Tunnel Release
- Where
- 2 sites in Netherlands
- Volunteers
- 2,604 people, healthy volunteers welcome
- Sponsor
- Gelre Hospitals
Peripheral Nervous System Diseases, Nerve Compression Syndromes
Dextrose, Corticosteroids and Surgical Release in Carpal Tunnel Syndrome
The objective of the present study is to compare the effectiveness of 5% dextrose, local corticosteroids injections and surgical release in patients with electrodiagnostically (EDx) mild to moderate carpal tunnel syndrome (CTS).
- Conditions
- Peripheral Nervous System Diseases, Nerve Compression Syndromes, Carpal Tunnel Syndrome
- Trial name
- NCT04014244
- Testing
- Corticosteroid vs. Dextrose, Corticosteroid or Dextrose vs. Surgery
- Where
- Slovenia
- Volunteers
- 100 people
- Sponsor
- University Medical Centre Ljubljana
Carpal Tunnel Syndrome
A Pilot Study to Evaluate the Effectiveness of Ultrasound Guided Looped Thread Carpal Tunnel Release
Carpal tunnel syndrome occurs when a nerve gets pinched as it passes through a confined tunnel within the wrist and hand. It is the most commonly pinched nerve and often results in disabling hand numbness, tingling, pain and…
- Trial name
- NCT03476486
- Testing
- Thread carpal tunnel release
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Carpal Tunnel Syndrome, Patient Satisfaction
Postoperative Care After Carpal Tunnel Release Using Short Educational Videos
The goal of this clinical trial is to learn if a patient-directed postoperative care program, using short educational videos, can improve patient satisfaction and reduce healthcare resource utilization in patients undergoing…
- Trial name
- VIDEO (NCT06647719)
- Testing
- Educational Videos
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Carilion Clinic
Carpal Tunnel Syndrome
Post-Operative Splinting After Short-Incision Carpal Tunnel Release: a Prospective Study
This research study is for patients who are schedule to have carpal tunnel release surgery. The investigators have developed this study in order to determine if post-operative splinting is effective in improvement of patient…
- Trial name
- NCT01897272
- Testing
- Splinting
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Christine M. Kleinert Institute for Hand and Microsurgery
Carpal Tunnel Syndrome (CTS)
Ultrasound-Guided Percutaneous Release vs. Open Surgery for Carpal Tunnel Syndrome
The goal of this clinical trial is to compare the clinical and functional outcomes of two surgical approaches for the treatment of carpal tunnel syndrome (CTS): ultrasound-guided percutaneous release of the flexor retinaculum and…
- Trial name
- NCT07230782
- Testing
- Percutaneous Ultrasound Guided Release of the Transverse Carpal Ligament, Open release surgery
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Fundacin Biomedica Galicia Sur
Carpal Tunnel Syndrome
Effects of Kinesiotaping With and Without Active Release Technique in Patients With Carpal Tunnel Syndrome
The goal of this study is to compare the effects of Kinesiotaping and Active Release Technique in patients with CTS to see which method is better for improving Pain, Grip Strength, Range of Motion and functional disability.
- Trial name
- NCT05354011
- Testing
- Kinesiotape, Active Release Technique
- Where
- Pakistan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Carpal Tunnel Syndrome
Carpal Tunnel Release Under Local Anaesthesia With or Without Distal Median Nerve Block
Carpal tunnel syndrome (CTS) is the most commonly appearing entrapment neuropathy of the upper extremity. Treatment options include both non-operative and operative methods.
- Trial name
- PERSONNEL (NCT05372393)
- Testing
- Local infiltration anaesthesia in carpal tunnel release, Distal median nerve block with local infiltration anaesthesia in carpal tunnel release
- Where
- Finland
- Volunteers
- 118 people
- Sponsor
- Kuopio University Hospital
Carpal Tunnel Syndrome
Carpal Tunnel Release Effects on Median Nerve Perfusion
This study aims to examine the effect of carpal tunnel release on blood flow to the median nerve using SPY scope imaging to view the perfusion to the nerve.
- Trial name
- NCT01610739
- Testing
- Indigocyanine green dye
- Where
- United States
- Sponsor
- Henry Ford Health System
Carpal Tunnel Syndrome, Hand Injuries and Disorders
The ACTS Trial: N-acetylcysteine (NAC) and Night-splinting as a Non-operative Treatment for Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common nerve compression syndrome worldwide, causing significant chronic pain, functional impairment, and lowered quality of life for individuals of various backgrounds.
- Conditions
- Carpal Tunnel Syndrome, Hand Injuries and Disorders, Nerve Compression, Splints
- Trial name
- ACTS (NCT04460521)
- Testing
- N-Acetyl cysteine, Wrist Splint
- Where
- Canada
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Emily Krauss
Carpal Tunnel Syndrome
Carpal Tunnel Release Via Two Small Incisions Comparing With Via Standard Incision And Under Endoscope
Carpal Tunnel Release via Two Small Incisions Comparing With via Standard Incision And Under Endoscope.
- Trial name
- CTR (NCT02500355)
- Testing
- Carpal Tunnel Release via limited approaches, Carpal Tunnel Release via standard approach, Endoscopic Carpal Tunnel Release
- Where
- China
- Volunteers
- 220 people
- Sponsor
- The Second Hospital of Qinhuangdao
Carpal Tunnel Syndrome
Percutaneous Treatment of Carpal Tunnel Syndrome With Scan
The objective of the study is to evaluate in patients suffering from carpal tunnel syndrome resistant to medical treatment, clinical course after percutaneous treatment under ultrasound guidance.
- Trial name
- ECHOCARPE (NCT02514317)
- Testing
- percutaneous treatment, Ultrasound
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Caen
Carpal Tunnel Syndrome
WALANT Versus Local Anesthesia With Tourniquet for Carpal Tunnel Decompression
This multicenter, randomized, double-blinded controlled trial compared two local anesthetic techniques for open carpal tunnel decompression in adults.
- Trial name
- WALANT vs LA-T (NCT07617064)
- Testing
- WALANT technique for carpal tunnel decompression, Local anesthesia with tourniquet for carpal tunnel decompression
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Misr University for Science and Technology
Compression Neuropathy, Carpal Tunnel Syndrome
4AP for Carpal Tunnel Syndrome (CTS)
The investigators have found recent promising data supporting the use of a currently FDA approved drug, 4-aminopyridine, in the treatment of nerve injury including compression neuropathy.
- Trial name
- CTS (NCT06294821)
- Testing
- 4-Aminopyridine
- Volunteers
- 160 people
- Sponsor
- John Elfar
Carpal Tunnel Syndrome (CTS), Lacertus Syndrome
MeDe Study: Comparing Median Nerve Decompression at the Carpal Tunnel Alone Versus Median Nerve Decompression at Both the Carpal Tunnel and Lacertus Fibrosis in Adults With Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is a condition that can cause pain, numbness, or tingling in the hand and wrist. The most common surgery for CTS is called carpal tunnel release, which aims to relieve pressure on the main nerve in…
- Trial name
- MeDe (NCT07594821)
- Testing
- Carpal tunnel release, Combined carpal tunnel and lacertus release
- Where
- 2 sites in Netherlands
- Volunteers
- 110 people
- Sponsor
- Maasstad Hospital
Carpal Tunnel Syndrome
Splinting After Mini-Open Carpal Tunnel Release
The purpose of this study is to determine if any difference exists among 3 different postoperative splinting regimens- no splint, removable splint, and plaster non-removable splint- following mini-open carpal tunnel release (CTR)…
- Trial name
- NCT02885701
- Testing
- No Splint, Removable Splint, Non-removable Splint
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Anthony L. Logli
Carpal Tunnel Syndrome, CTS
Multicenter Prospective Trial of Office-based Carpal Tunnel Release With Ultrasound Guidance (ROBUST)
Multicenter prospective single-arm trial of subjects with symptomatic Carpal Tunnel Syndrome treated with Ultrasound Guided Carpal Tunnel Release (CTR-US) in an office-based setting.
- Trial name
- ROBUST (NCT05675046)
- Testing
- Carpal Tunnel Release with Ultrasound Guidance using the UltraGuideCTR device
- Where
- 7 sites in United States
- Volunteers
- 149 people
- Sponsor
- Sonex Health, Inc.
Bier Block, Dexmedetomidine
A Sequential Allocation Study to Determine the ED50 of Dexmetedomidine as an Adjuvant to Lidocaine Intravenous Regional Anesthesia
Intravenous Regional Anesthesia (IVRA) is an easy and reliable anesthetic technique for hand and forearm surgery. Its use is however limited by the presence of tourniquet pain during the surgery and the absence of postoperative…
- Conditions
- Bier Block, Dexmedetomidine, Tourniquet Pain, Carpal Tunnel
- Trial name
- NCT05342870
- Testing
- Dexmedetomidine
- Volunteers
- 23 people
- Sponsor
- American University of Beirut Medical Center