Clinical trials: Caries
Dental Caries in Children
Comparing the Effectiveness of Papain Based Chemico-mechanical Caries Removal Gel and 38% Silver Diamine Fluoride for Treating Active Caries Lesion of Primary Molars
This study aims to investigate the efficacy of silver diamine fluoride (SDF) and Papain-based chemico-mechanical caries removal gel and using ceramic bur as a control in treating dentine caries in primary molars aged 7-8 years…
- Trial name
- NCT06412731
- Testing
- Cera-bur, Brix3000, E-SDF
- Where
- Iraq
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Caries Class II
Clinical Evaluation of Fiber Reinforced Resin Composite Base Versus Incremental Packing of Nanohybrid Resin Composite
A clinical trial, comparing two different incrementation techniques in the restoration of proximal caries in permanent posterior teeth .
- Trial name
- NCT04019145
- Testing
- EverX Posterior, Resins, Composite
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Nursing Caries, Laughter
The Effect of Laughter Yoga on Loneliness, Anger and Salivary Cortisol Levels in Visually Impaired Individuals
Purpose: This project aimed to examine the effects of laughter yoga, which is accepted as an international nursing initiative, on loneliness, anger and salivary cortisol levels in visually impaired individuals.
- Conditions
- Nursing Caries, Laughter, Visual Impairment, Loneliness
- Trial name
- NCT06308601
- Testing
- Laughter yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ege University
Dental Caries, Caries,Dental
Caries Prevalence, Experience and Risk Related Factors Among Early Middle-aged Patients Attending Cairo University
Dental caries, a widespread oral health issue, results from a complex interplay of factors including behavior, hygiene, diet, and socio-demographic aspects.
- Trial name
- NCT06365281
- Where
- Egypt
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Cairo University
Poor Aesthetic of Existing Restoration of Tooth, Dental Restoration Failure of Marginal Integrity
The Effect of Different Adhesion Strategies on the Clinical Success
The study will involve 41 people who regularly seek treatment at clinics. Participants must be in generally good health and be older than eighteen.
- Conditions
- Poor Aesthetic of Existing Restoration of Tooth, Dental Restoration Failure of Marginal Integrity, Unacceptable Morphology of Tooth Restoration, Secondary Caries
- Trial name
- NCT06500546
- Testing
- Treatment of cervical lesions
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Dental Caries, Obesity Prevention
Advancing Water Security: A Community Participatory School-Based Hydration Intervention
The goal of this study is to determine the effectiveness and sustainability of a community-participatory hydration intervention over 3 years within a district that has newly installed hydration stations and is operating under a…
- Trial name
- NCT06714929
- Testing
- Hydration
- Where
- United States
- Volunteers
- 7,200 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Secondary Caries, Dental Restoration Failure of Marginal Integrity
Comparative Evaluation of Class V Restorations
To evaluate and compare the 2-year clinical performance of Class V restorations using various restorative systems with ion-releasing and non-ion-releasing composites, utilizing fluoride-free and fluoride-releasing universal…
- Trial name
- NCT06164418
- Testing
- Dental restoration
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Caries, Dental
The Effects of Stainless Steel Crowns Applied With Hall Technique on Occlusal Vertical Dimension
In recent years restoring carious of fractured primary teeth with stainless steel crowns (SSC) has became more popular than ever.
- Trial name
- NCT03010618
- Testing
- Hall technique stainless steel crowns
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Root Caries
Evaluation of Corrective Surgery Versus Dental Implants in Compromised Upper Molars
This study seeks to assess the clinical, radiographic, and patient-reported outcomes of root amputation versus implant over a 12 months period, generating robust evidence to guide clinical decision-making and enhance patient care.
- Trial name
- NCT07608497
- Testing
- root amputation
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Inflammatory Bowel Diseases, Periodontitis
Oral Health-related Quality of Life (OHRQoL) in Patients With Inflammatory Bowel Disease (IBD)
IBD patients have a higher risk of oral diseases that affect the oral mucosa, the teeth and the tooth supporting tissues. These conditions are often associated with pain, bleeding and impaired masticatory function which may have…
- Conditions
- Inflammatory Bowel Diseases, Periodontitis, Dental Caries, Tooth Loss
- Trial name
- OQal-MICI (NCT05096897)
- Testing
- Self-administrated questionnaires
- Where
- France
- Volunteers
- 138 people
- Sponsor
- University Hospital, Lille
Unsatisfactory Restoration of Tooth, Carious Teeth
Biological and Esthetic Evaluation of Ceramic Onlay With Different Preparation Designs
Aim of study: is to asses biological and esthetical success of ceramic onlay restorations while preparing the teeth using shoulder finish line preparation versus butt joint with bevel preparation.
- Trial name
- NCT04438642
- Testing
- shoulder finishline, butt joint with bevel
- Where
- Egypt
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Ahmed Adel Mahmoud Gadallah
High Caries Risk Patients, Antimicrobial Effect
Antibacterial Effect of Guava Leaves Extract Mouthwash Compared to Chlorhexidine Mouthwash in High Caries Risk Patients
This trial is to test the antibacterial effect of Guava leaves extract mouth wash compared to Chlorhexidine mouth wash in high caries risk patients. Also salivary pH and patient satisfaction to taste will also be tested.
- Conditions
- High Caries Risk Patients, Antimicrobial Effect, Salivary pH, Patient Satisfaction to Taste
- Trial name
- NCT03773094
- Testing
- Guava leaves extract, Chlorhexidine
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Cairo University
Restored Decayed Teeth and Post-operative Sensitivity
Dental Cement in Post-operative Sensitivity: Randomized Clinical Trial
Context: CEMENT PBS CIMMO DTA® has physical and biological properties that classify it as a biocompatible material and inducer of biomineralization, attributes that qualify it as material as an indirect pulp capper in permanent…
- Trial name
- Bioactivity (NCT04870294)
- Testing
- Teeth treated with composite resin, control group, Teeth treated with lining, pulp wall with PBS DTA® cement and composite resin restoration
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Sapucai
Preterm Infants, Injector
The Effect of Different Feeding Methods on Infants
Objective: The aim of this study was to investigate the effect of finger feeding and syringe feeding methods on infant weight, time to full oral feeding and breastfeeding success in preterm infants.
- Conditions
- Preterm Infants, Injector, Finger, Sucking Success
- Trial name
- NCT06737796
- Testing
- Finger Feeding, syringe feeding
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Tooth Decay
Comparing the Clinical Success of Two Different CAD/CAM Full Cuspal Coverage Onlays
This is a single-center, ten-year, randomized controlled, split-mouth clinical trial. A total of 164 adult patients requiring full-cuspal coverage onlays will be enrolled.
- Trial name
- CUSTOM (NCT07519382)
- Testing
- full cuspal covarage onlay
- Where
- Hungary
- Volunteers
- 164 people
- Sponsor
- Semmelweis University
Oral Hygiene
The Effect of Experimental Dentifrices on Remineralization of Caries Lesions In-situ
This study will evaluate the effect of experimental sodium fluoride-silica dentifrice formulations, with and without zinc, on remineralization of enamel in situ.
- Trial name
- NCT02195583
- Testing
- Sodium fluoride (1426 ppm), Sodium fluoride (1150 ppm), Sodium fluoride (250 ppm)
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dental Caries
Fluoride Application on Preventing and Arresting Root Caries in Fluoridated and Non-fluoridated Areas
This study was a randomized clinical trial lasting for 24 months in two study sites, Hong Kong (water fluoridated) and Guangzhou (non-fluoridated area).
- Trial name
- NCT02742142
- Testing
- silver diammine fluoride
- Where
- 2 sites in China
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Dental Plaque, Dental Caries
Probiotic Treatment of Orthodontic Patients
The purpose of this study is to examine the effect of treatment with a lozenge containing the probiotic strain S. salivarius M18 on the formation, composition and virulence of dental plaque and in healthy orthodontic patients…
- Trial name
- NCT06751979
- Testing
- Probiotic treatment
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Insufficient Dental Filling or Primary Caries (Class I or II Cavities in Premolars or Molars)
Clinical Evaluation of a New Flowable and a New Sculptable Universal Bulk-fill Composite for Direct Restorative Treatment
The overall objective of this clinical investigation is to evaluate the clinical safety and performance of the new flowable composite TM Flow and the new sculptable composite TM Fill for restoration of class I and class II…
- Trial name
- NCT06369779
- Testing
- TM Fill in combination with TM Flow
- Where
- Liechtenstein
- Volunteers
- 65 people
- Sponsor
- Ivoclar Vivadent AG
pH, Saliva
Carbonated Beverage Consumption in pH and Bacterial Proliferation
The objective of this research is to evaluate the oral modifications caused by different types of coke drinks (regular coke and diet coke).
- Conditions
- pH, Saliva, Dental Plaque
- Trial name
- pHSB (NCT05437874)
- Testing
- Natural Water
- Where
- Mexico
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hospital Infantil de Mexico Federico Gomez