Clinical trials: Caries, Dental
Dental Caries
Comparison of the Effect of Fluoride Remineralizer Gel and Foam
Compare the remineralizing effect of acidulated fluoride gel Flugel (1.23% FFA, DFL) and acidulated Fluoride Foam Flúor Care (1.23% FFA, FGM) in maxillary anterior permanent teeth of 58 children aged 7 to 12 years of age.
- Trial name
- NCT02490592
- Testing
- Fluoride Foam, Fluoride gel
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University Center of João Pessoa
Cervical Caries
18-Month Clinical Evaluation of Self-Adhesive Flowable Giomer Compared to Conventional Flowable Giomer in Carious Cervical Lesions: A Randomized Clinical Trial
The material under investigation will offer the patient a high strength and high durability restoration with the advantage of having anti-bacterial properties.
- Trial name
- NCT06946134
- Testing
- FIT SA, Beautifil Flow Plus F00
- Volunteers
- 34 people
- Sponsor
- Cairo University
Dental Caries
Radiographic Progression of Sealed and Infiltrated Caries Lesions in Vivo
The purpose of this study was to compare with a clinical randomized controlled split-mouth design study the changes in the therapeutic effect of infiltrating versus sealing proximal caries lesions and placebo treatment after 1, 2…
- Trial name
- NCT01417832
- Testing
- Resin infiltration / adhesive
- Where
- Colombia
- Volunteers
- 37 people
- Sponsor
- Universidad El Bosque, Bogotá
Dental Caries, Tooth Wear
DIMOH: New Digital Methods for Monitoring Oral Health. An in Vivo Assessment
The objectives of this study are i) to monitor the oral health of young people over a period of one year and ii) to assess the ability of a new intraoral scanner combining fluorescence with 3D imaging to detect and monitor…
- Trial name
- NCT04050306
- Where
- 2 sites in Denmark, Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dental Caries
A Comparative Study of Hall Technique, Modified Hall Technique and Conventional Stainless-Steel Crown Restorations in the Treatment of Primary Molars With Proximal Caries Lesions.
The purpose of this study is to compare the effectiveness of the Hall technique and modified Hall technique to the conventional Stainless-Steel Crown restoration in the treatment of primary molars with dentinal caries with or…
- Trial name
- NCT04822233
- Testing
- Hall Technique (HT), Modified Hall Technique (MHT), Conventional Technique (CT)
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- The University of Texas Health Science Center, Houston
Tooth Loss, Tooth Diseases
The Cortical Shield for Facial Bone Reconstruction
To evaluate a novel technique of bone regeneration and simultaneous implant placement in severely damaged sockets.
- Conditions
- Tooth Loss, Tooth Diseases, Tooth Fracture, Tooth Injuries
- Trial name
- NCT04827693
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Verdugo, Fernando, DDS
Dental Caries of Root Surface, Surgery
Intraoral Imaging at Clinical Crown Lengthening
Crown lengthening surgery is done when a tooth needs to be fixed with a crown. Sometimes, not enough of the tooth sticks out above the gum to support a crown.
- Trial name
- NCT03064217
- Testing
- Making impression at surgery
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Gingival Inflammation, Dental Caries
Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences
Objectives: To evaluate the effectiveness of toothpaste tablets when compared to conventional dentifrices in removing plaque. Methods: 50 participants are randomized into two groups: Denttabs toothpaste tablets (T) and Colgate's…
- Trial name
- NCT07124533
- Testing
- Toothpaste Tablet, Conventional Toothpaste
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Dental Caries
Sealing Manifest Occlusal Caries Lesions in the Permanent Dentition
The research project "SEAL-DK" is focusing on advantages and disadvantages of two treatment strategies: non-invasive fissure sealing and invasive restorative treatment of manifest occlusal caries lesions in permanent teeth in…
- Trial name
- SEAL-DK (NCT02573090)
- Testing
- Non-invasive resin based fissure sealing, Invasive resin based restoration
- Volunteers
- 521 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dental Caries
Evaluation of Preventive Regimens With Different Toothpastes vs Fluoride Varnish & Toothpaste in High Caries Patients
This study will be conducted in order to determine the prevention effect of caries preventive regimen using herbal toothpaste and regimen using fluoride toothpaste versus fluoride toothpaste and fluoride varnish on the caries…
- Trial name
- NCT04436913
- Testing
- Himalaya complete care toothpaste, Signal toothpaste, Signal toothpaste and fluoride varnish
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Infection, Bacterial
Evaluation of Gel and Solution of Chlorhexidine in Disinfection Root Canals of Primary Anterior Teeth.
The process of removing bacteria and their products from the root canals is an essential step that is achieved through the combination of mechanical preparation and irrigation with chemicals.
- Conditions
- Dental Caries, Infection, Bacterial, Tooth, Deciduous
- Trial name
- NCT05361278
- Testing
- Chlorhexidine solution, Activated chlorhexidine solution, Chlorhexidine gel
- Where
- Syria
- Volunteers
- 15 people
- Sponsor
- Damascus University
Dental Caries
CAMBRA - PBRN Caries Management By Risk Assessment In A Practice-Based Research Network
The goal of this project is to create a Practice Based Research Network with 30 researcher dentists calibrated on the administration of a caries risk assessment and the treatment modalities recommended based on the caries risk…
- Trial name
- CAMBRA-PBRN (NCT01176396)
- Testing
- Caries prevention active intervention, control treatment
- Where
- United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dental Caries Extending to Pulp, Pulp Disease, Dental
Assessment of Vital Pulp Therapy in Permanent Molars
The purpose of this study is to evaluate the long term clinical performance of vital pulp therapy of young permanent teeth with irreversible pulpitis
- Trial name
- NCT03410134
- Testing
- NeoMTA
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Caries, Dental Materials
Carious Tissue Selective Removal on Permanent Posterior Teeth.
This study is a prospective randomized controlled study of patients who come to the University. The aim is to evaluate the success rate of selective removal of carious tissue in deep lesions of posterior teeth.
- Trial name
- NCT04533113
- Testing
- Carious tissue selective removal
- Where
- Spain
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Juan Gonzalo Olivieri
Decayed Teeth
Effect of Bone Marrow Mononuclear Cell Layer Seeded on Platelet-rich Fibrin on an Alveolar Socket After Extraction
Bone marrow aspiration from maxillary tuberosity will be centrifuged to separate the bone marrow mononuclear cell layer using the density gradient separation method, then it will be seeded in a platelet-rich fibrin membrane and…
- Trial name
- NCT05465421
- Testing
- bone marrow aspiration from maxillary tuberosity and BMMNCs separation to be seeded on PRF and used for socket preservation
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Deep Caries, Pulpitis Reversible
The Prognostic Impact of Symptoms and Lesion Depth in Partial Removal of Carious Tissue
The goal of this prospective, observational clinical cohort study is to study the effect of the preoperative condition of the tooth on the outcome of partial removal of carious tissue in mature teeth in adults.
- Conditions
- Deep Caries, Pulpitis Reversible, Pulp Hyperemia
- Trial name
- NCT05816525
- Testing
- Partial removal of carious tissue, Final restoration
- Where
- Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Caries, Dental
Clinical Evaluation of ELS Versus ELS Extra Resin Composite
Adhesive restorative materials are routinely used in operative dentistry to improve tooth tissues with minimal preparation, achieve more esthetic and long term restorations.
- Trial name
- NCT03306576
- Testing
- ELS Extra composite, ELS composite
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Medipol University Hospital
Carious Cervical Lesions
Self-Cure vs. Highly Filled Flowable Composite in Carious Cervical Lesions: 18-Month RCT
The aim of the study is to compare and evaluate the clinical performance of a self cure composite system versus a highly filled flowable composite in the restoration of carious cervical lesions over an 18 months follow up period.
- Trial name
- NCT07576673
- Testing
- Class V Restoration - Polofil, Class V Restoration - Stela
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Dental Caries
Safety Evaluation of Advantage Anti-Caries Varnish
The purpose of the study is to confirm the safety of Advantage Anti-Caries Varnish.
- Trial name
- NCT02645617
- Testing
- Varnish
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Advantage Dental Services, LLC
Dental Caries, Dry Mouth
Oral Health Intervention in Adult Primary Care
This study is a Stage III cRCT to test the efficacy of multi-level interventions at the practice- and provider-level to address low dental utilization (attendance) among Medicaid-enrolled older adults 55 years or older attending…
- Conditions
- Dental Caries, Dry Mouth, Periodontal Diseases, Bleeding Gum
- Trial name
- NCT06555029
- Testing
- EHR Changes, Medical Staff EHR Training, Clinician CSM theory-based didactic education and skills training, Standard ADA Oral Health Training
- Where
- United States
- Volunteers
- 929 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
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