Clinical trials: Cardiovascular Fitness
Cognitive Decline, Executive Dysfunction
Fitness on White Matter and Cognition in Aging
Cardiorespiratory fitness (CRF) is associated with decreased risk for mild cognitive impairment (MCI) and dementia. CRF is linked with more conserved gray and white matter (WM) volume, improved WM microstructural integrity, and…
- Conditions
- Cognitive Decline, Executive Dysfunction, Cardiovascular Risk Factor
- Trial name
- NCT03775941
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- Suffolk University
Rheumatoid Arthritis, Physical Activity
The Effects of a Six-week Exercise Programme Undertaken by Women With Rheumatoid Arthritis
This study is investigating whether a six-week exercise training programme, designed for patients with Rheumatoid Arthritis, improves disease activity, inflammation, cardiorespiratory fitness, muscle strength, flexibility and…
- Trial name
- NCT02819830
- Testing
- Exercise Intervention
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Siobhan Graham
Healthy Subjects
Cardiovascular Fitness and Venous Function in Trained and Untrained Subjects
The primary aim is to study the relationship between vascular function, cardiovascular fitness and age in healthy subjects. Individuals with the highest cardiovascular fitness will have the greatest arterial inflow independent of…
- Trial name
- NCT01215630
- Testing
- Aerobic Interval Training
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Prostatic Neoplasms, Exercise
Health Effects of Soccer Training in Men With Prostate Cancer Receiving Androgen Deprivation Therapy
Androgen Deprivation Therapy (ADT) is standard treatment for locally advanced or advanced Prostate Cancer (PC). The musculoskeletal toxicity associated with ADT is well established, leading to a decrease in muscle mass, increased…
- Conditions
- Prostatic Neoplasms, Exercise, Soccer Training, Androgen Deprivation Therapy
- Trial name
- NCT01711892
- Testing
- Soccer training
- Where
- Denmark
- Volunteers
- 57 people
- Sponsor
- University of Copenhagen
Multiple Sclerosis
Effect of Active-Passive Trainer Cycling on Multiple Sclerosis
This randomised controlled trial aims to explore the effectiveness of a four week programme of exercise using lower limb Active Passive trainer (APT) (MOTOmed trainer) in terms of spasticity in people with moderate to severe…
- Trial name
- NCT02737904
- Testing
- APT, Usual care
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- NHS Greater Glasgow and Clyde
Refractory Epilepsy
Randomized Controlled Trial on Cardiovascular Exercise in Uncontrolled Epilepsy:
This is an open-label randomized controlled tria testing if an improvement in cardiovascular fitness can improve quality of Life and reduce seizure frequency in patients with refractory epilepsy..
- Trial name
- Epilepsy (NCT03570489)
- Testing
- Exercise, Relaxation
- Where
- Sweden
- Volunteers
- 28 people
- Sponsor
- Vastra Gotaland Region
MINOCA, Shortness of Breath
Determinants of Cardiorespiratory Fitness and Effects of HIIT in Patients With ANOCA Obstructive Coronary Artery Disease(ANOCA)
The main goal is to understand what causes reduced fitness in ANOCA and whether targeted exercise can help improve it. This study aims to better understand why patients with Angina and No Obstructive Coronary Artery Disease…
- Conditions
- MINOCA, Shortness of Breath, Atherosclerotic Heart Disease of Native Coronary Artery
- Trial name
- NCT07182955
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Virginia
Multiple Sclerosis, Progressive
The Effect of High Intensity Interval Training on Cardiovascular Fitness in People With Progressive Multiple Sclerosis.
This is a pilot trial to explore the cardiovascular of eight weeks of twice weekly high intensity interval training in people with progressive multiple sclerosis.
- Trial name
- NCT02950454
- Testing
- High intensity interval training, Continuous moderate exercise
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Cardiovascular Risk Factor, Lipemia
Postprandial Monocyte Maturation and Vascular Dysfunction Following High-Fat Meals - Study 1
The purpose of this research study is to examine the effect of high-fat meals on the health of blood vessels. In addition, the study will examine how exercise/fitness/physical activity impacts blood vessels after consumption of a…
- Trial name
- NCT03958734
- Testing
- High-fat meal
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Healthy Participants
The UBC Long-distance Triathlon Adaptation Study
The purpose of this study is to investigate the effect of 12-months of individualized endurance-training (swimming, cycling and running) on physiological and psychological adaptations in exercise naïve individuals.
- Trial name
- ULTRA (NCT06467656)
- Testing
- Individualized, periodized endurance training for ultra-endurance triathlon., Time-Aligned Control
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Aging, Stress
Fitness, Cellular Aging, and Caregiver Stress Study
The purpose of this study is to determine whether an aerobic training intervention will alter markers of immune cell aging, improve exercise capacity and blood pressure and decrease psychological distress over 24 weeks in 32…
- Conditions
- Aging, Stress, Disease Risk
- Trial name
- FAST (NCT01993082)
- Testing
- Aerobic Training Intervention
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Child Behavior, Adolescent Behavior
Effect of Judo Training Compared to Ball Games on Motor Skills, Physical Fitness, Quality of Life and Cardiovascular Parameters in Children and Adolescents
There will be a three-month intervention with two groups: judo training and ball games, twice a week, for 50 minutes. The sample will consist of children and adolescents with low socioeconomic status, participants of a…
- Trial name
- NCT03068000
- Testing
- Judo Training, Ball Games
- Where
- Brazil
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Acute Coronary Syndrome
Impact of a Digital Solution (CardiCare™) on Cardiorespiratory Fitness Improvement in Patients Discharged From a Phase 2 Cardiac Rehabilitation Following an Acute Coronary Syndrome
Coronary heart disease is a partial inability of the coronary arteries to supply the heart muscle due to their narrowing. There is angina and myocardial infarction.
- Trial name
- NCT04294940
- Testing
- Wear an actigraph, Use the mobile application CardiCare™ and wear an actigraph
- Where
- 10 sites in France, Italy and 2 more
- Sponsor
- Ad scientiam
Obesity, Cardiovascular Fitness
Systematic Initiative to Increase Activity in Schools
This initiative is a prospective study evaluating the effects of implementing physical activity strategies in Wisconsin schools with low socioeconomic status on childhood fitness.
- Trial name
- NCT02411552
- Testing
- physical activity
- Volunteers
- 4,894 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Inactive 30-50-year-old Men
Recreational Football for Young-to-middle-aged Inactive Men
The aim of this study was to examine the health and physical fitness effects of 12 weeks of recreational football in inactive 30-50-year-old men.
- Trial name
- NCT07804563
- Testing
- Experimental: Intervention group
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Turner Syndrome, Turner Syndrome Mosaicism, 45, X/46, XX or XY
Health, Fitness, and Quality of Life in Adolescent Girls With Turner Syndrome
This study plans to learn more about how the energy system works in girls with Turner syndrome. This is important to know so that the investigators understand how Turner syndrome relates to diseases such as diabetes, extra weight…
- Conditions
- Turner Syndrome, Turner Syndrome Mosaicism, 45, X/46, XX or XY, Turner Syndrome Mosaicism 46,X,I(X)(Q10)/45,X, Turner Syndrome Karyotype 46,X With Abnormal Sex Chromosome , Except I(Xq)
- Trial name
- NCT03181230
- Testing
- No intervention
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Colorado, Denver
Cardiovascular Fitness
Physiological and Perceptual Responses During 4-Second Exercise
The purpose of this study is to investigate the acute effects of different intensities (i.e., 50, 75, and 100% of maximal anaerobic power) of 4-s sprint interval exercise on physiological responses.
- Trial name
- NCT06912932
- Testing
- Preventive
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Hypertrophic Cardiomyopathy
High Intensity Exercise for Increasing Fitness in Patients With Hypertrophic Cardiomyopathy
Although current clinical guidelines stipulate that patients with hypertrophic cardiomyopathy should not partake in high intensity exercise (HIE) or competitive sport due to safety concerns, there is no clear evidence to support…
- Trial name
- NCT03335332
- Testing
- High intensity exercise, Moderate intensity exercise
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Texas Southwestern Medical Center