Clinical trials: Cardiac Sarcoidosis
Cardiac Sarcoidosis
Interleukin-1 Blockade for Treatment of Cardiac Sarcoidosis
Sarcoidosis is a heterogeneous disorder of unknown etiology whose signature lesions are granulomatous inflammatory infiltrates in involved tissues. Tissue commonly affected are lungs, skin, eyes, lymph nodes and the heart.
- Trial name
- MAGiC-ART (NCT04017936)
- Testing
- Anakinra
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Virginia Commonwealth University
Emphysema, Chronic Obstructive Pulmonary Disease (COPD)
Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability
The purpose of this research study is to learn about the safety of transplanting lungs obtained from non-heart-beating donors (NHBDs) that have been ventilated (attached to a breathing machine or ventilator to deliver oxygen) and…
- Conditions
- Emphysema, Chronic Obstructive Pulmonary Disease (COPD), Cystic Fibrosis, Pulmonary Fibrosis
- Trial name
- NCT01615484
- Testing
- Transplantation of lungs obtained from Non-Heart-Beating Donors (NHBDs) after ex-vivo perfusion w/ STEEN Solution™, STEEN Solution™
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- University of North Carolina, Chapel Hill
Sarcoidosis
Somatostatin Receptor Imaging in Patients With Suspected Cardiac Sarcoidosis
The purpose of this research study to find out if a drug called OctreoScan or DOTATATE can help doctors diagnose people with cardiac sarcoidosis better. OctreoScan and DOTATATE are both approved by the U.S.
- Trial name
- NCT02546388
- Testing
- Indium-111 Pentreotide, Gallium-68 DOTATATE
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Marcelo F. Di Carli, MD, FACC
Cardiac Sarcoidosis
d68Ga-DOTATATE PET/CT Assessment of Cardiac Sarcoidosis
The Researchers are trying to determine if 68Ga-DOTATATE PET/CT imaging will have a similar accuracy as 18FDG PET/CT in diagnosing cardiac sarcoidosis and if it will be able to do so without the need for complex patient dietary…
- Trial name
- NCT03549598
- Testing
- 68Ga-DOTATATE PET/CT, 18FDG PET/CT scan, 13NH3 PET/CT scan
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mayo Clinic
Cardiac Sarcoidosis, Myocardial Inflammation
18F-FSPG PET/MRI or PET/CT Imaging of Cardiac Sarcoidosis or Inflammation
The investigators will evaluate the detection of cardiac sarcoidosis or inflammation using 18F-FSPG PET/MRI (or PET/CT for participants with metal implants).
- Trial name
- NCT03103490
- Testing
- 18F-FSPG
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Stanford University
Cardiac Sarcoidosis
Non-Invasive Characterization in Cardiac Sarcoidosis
In a study of Cardiac sarcoidosis, a serious heart condition, a radiotracer is being used to examine inflammation.
- Trial name
- NCT02017522
- Testing
- 11C-PBR PET
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Michigan
Sarcoidosis, Cardiac
A Study to Assess the Safety, Tolerability, and Efficacy of Namilumab in Participants With Active Cardiac Sarcoidosis
A Randomized, Double-blind, Placebo-controlled, Study with an Open-label Cohort.
- Trial name
- RESOLVE-Heart (NCT05351554)
- Testing
- Namilumab
- Where
- 12 sites in United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Kinevant Sciences GmbH