Clinical trials: Cardiac Output,Low
Cardiac Output, Low
Real-time Continuous Cardiac Output Measurements
Study to assess the feasibility of real-time automatic cardiac output measurements using transthoracic echocardiography (TTE)
- Trial name
- NCT04774978
- Testing
- TTE
- Volunteers
- 20 people
- Sponsor
- Rijnstate Hospital
Shock, Cardiogenic, Surgery
Validity of Cardiac Output Measurement Using Niccomo Device After Cardiac Surgery
Cardiac surgery is at high risk of low cardiac output syndrome after procedure. Monitoring cardiac function, and especially cardiac output, is important to identify cardiovascular dysfunction and to introduce and adjust optimal…
- Conditions
- Shock, Cardiogenic, Surgery, Output, Low Cardiac
- Trial name
- Niccomo-Card (NCT04643509)
- Testing
- Niccomo
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Rouen
Cardiac Output, Low, Surgery
Validation of Automated Cardiac Output Measurement
Automated software analysis now allows for quick estimation of cardiac output from the echocardiographic 5-chamber view. This study will validate the automated software method against pulmonary artery thermodilution and against…
- Trial name
- NCT03372863
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Cardiac Surgery, Extracorporeal Circulation; Complications
Evaluation of Blood and Cardiac Protein O-GlcNAcylation Levels in Cardiac Surgery in Children
Cardiac surgery requires the use of extracorporeal circulation (ECC). Age-related differences in inflammatory response, the greater susceptibility of immature organ systems to injury and the larger ratio of extracorporeal…
- Conditions
- Cardiac Surgery, Extracorporeal Circulation; Complications, Metabolism, Low Cardiac Output
- Trial name
- CardiOGlcNAc (NCT06754709)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Nantes University Hospital
Cardiac Output, Low, Anesthesia
Comparison of the Ability of the esCCO and the Volume View to Measure Trends in Cardiac Output During Cardiac Surgery
The purpose of this study was to compare CO measured by two easy to use non-invasive monitors, the esCCO (Nihon Kohden, Tokyo, Japan) to the Volume View (Edwards Lifesciences, Irvine, USA) and to assess their trending ability in…
- Trial name
- NCT02964663
- Testing
- esCCO
- Where
- Belgium
- Volunteers
- 19 people
- Sponsor
- Université Libre de Bruxelles
Surgery, Cardiac Output, Low
Reliability of a New Pulse Contour Technique for Diagnosing an Increase in Stroke Volume During a Fluid Challenge for Hemodynamic Optimization in Patients Scheduled for High-risk Abdominal Surgery: Comparison With Transthoracic Echocardiography: COMPARE Study
The present study aims at assessing the ability of a new pulse contour device for diagnosing a >15% stroke volume (SV) increase during patient hemodynamic optimization by fluid challenge in high risk abdominal surgery.
- Trial name
- COMPARE (NCT04871620)
- Testing
- >15% SV increase during fluid challenge
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Body Fluid Retention, Impedance
Effect of Passive Leg Raising for Fluid Responsiveness
Changes in volumetric hemodynamic parameters and fluid overload (Cardiac Index,Stroke Volume, Thoracic Fluid Content, Systemic Vascular Resistance) were measured using a impedance cardiography (ICG) (CardioScreen 1000 …
- Conditions
- Body Fluid Retention, Impedance, Cardiac Output, Low
- Trial name
- NCT02702544
- Testing
- CardioScreen 1000 - Haemodynamic Measurement System, Medis, SCHILLER, BR-102 plus - Ambulatory Blood Pressure Monitoring System
- Where
- Poland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Shock, Sepsis
Hemodynamic Evaluation of Preload Responsiveness in Children by Using PiCCO
The purpose of this study is To assess the value of dynamics (SVV, PPV) and static indices (GEDVI, ITBVI, CVP) of preload and its combination with contractility (CI,SV, ventricular power, dP/dtmax, CFI, GEF) and lung water…
- Conditions
- Shock, Sepsis, Systemic Inflammatory Response Syndrome, Low Cardiac Output
- Trial name
- PreloaDren (NCT01157299)
- Where
- 7 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Universitario La Paz
Cardiac Output, Low
Comparison Studies Comparing Hemodynamic Parameters Provided by the Caretaker Against Respective Gold Standard References
Comparison studies comparing hemodynamic parameters provided by the Caretaker against respective Gold Standard references.
- Trial name
- NCT05035719
- Testing
- non-invasive cardiac output monitor
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- CareTaker Medical LLC
Acute Heart Failure, Low Output Heart Failure
Postcardiotomy Venoarterial Extracorporeal Membrane Oxygenation
Cardiac surgery can be not infrequently complicated by cardiac low-output syndrome due to critical preoperative conditions such as cardiogenic shock, poor left ventricular function and severe myocardial ischemia.
- Conditions
- Acute Heart Failure, Low Output Heart Failure, Cardiac Output, Low, Extracorporeal Membrane Oxygenation
- Trial name
- PC-ECMO (NCT03508505)
- Testing
- Venoarterial extracorporeal oxygenation
- Where
- Finland
- Volunteers
- 1,000 people
- Sponsor
- Turku University Hospital
Cardiac Output, Low
Effects of Inspiratory Flow Waveforms on Preload
The clinical usefulness of inspiratory flow pattern manipulation during mechanical ventilation remains unclear. The aim of this study was to investigate the effects of different inspiratory flow waveforms, i.e.
- Trial name
- NCT01892696
- Testing
- varying inspiratory flow waveforms
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- Military Hospital of Tunis
Cardiac Output,Low, Hemodynamic Instability
Cardiac Output Changes in Cesarean Section
Since 2011, phenylephrine was recommended as the preferred drug to maintain blood pressure in obstetric anesthesia.Phenylephrine, an α adrenoceptor agonist, can induce peripheral vasoconstriction to maintain blood pressure, while…
- Conditions
- Cardiac Output,Low, Hemodynamic Instability, Obstetrical Complication of Anesthesia
- Trial name
- NCT02759510
- Testing
- Norepinephrine, Phenylephrine
- Volunteers
- 106 people
- Sponsor
- RenJi Hospital
Congestive Heart Failure, Low Cardiac Output
Losartan in Decompensated Heart Failure
The dual blockade of the renin-angiotensin-aldosterone system with an angiotensin-converting enzyme inhibitor and an angiotensin-receptor blocker used together in heart failure patients has been demonstrated to be beneficial.
- Trial name
- NCT01857999
- Testing
- Losartan
- Where
- Brazil
- Volunteers
- 21 people
- Sponsor
- InCor Heart Institute
Hemodynamic Instability
Pulse Pressure Variation Helps to Predict Fluid Responsiveness in Patients Ventilated With Low Tidal Volumes
Objective: To determine the value of pulse pressure variation (ΔRESPPP) to predict fluid responsiveness in patients ventilated with low tidal volumes (VT), and to investigate whether a lower ΔRESPPP cut-off point should be used…
- Trial name
- NCT01569308
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Low Cardiac Output Syndrome
Levosimendan Administration in Neonates With Transposition of the Great Arteries
Calcium sensitizer drugs such as Levosimendan may exert anti-ischemic effect in addition to positive inotropic and anti-stunning effects mediated by the opening of ATP-sensitive potassium (KATP) channels.
- Trial name
- NCT01120106
- Testing
- levosimendan
- Where
- Italy
- Volunteers
- 63 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Apnea of Prematurity, Preterm Birth
Hemodynamic Responses to Cardio-respiratory Events in Preterm Infants
Intermittent episodes of hypoxemia and/or bradycardia, also defined as cardio-respiratory events (CRE) are very frequent in preterm infants and may result in transient hypoxia and hypoperfusion of target organs, with possible…
- Conditions
- Apnea of Prematurity, Preterm Birth, Patent Ductus Arteriosus, Hypoxia, Brain
- Trial name
- NCT04184245
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Healthy
Determination of Variances in Exhaled Nitric Oxide Output in Normal Healthy Male Volunteers Consuming High and Low Nitrate/Nitrite Diets
This study will determine whether and how nitrites and nitrates in the diet affect the level of nitric oxide gas that is breathed out in air.
- Trial name
- NCT00027157
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiac Output, Low
Cardiac Output Autonomic Stimulation Therapy for Heart Failure (COAST-HF) - Human NeuroCatheter Study
A single-center feasibility study in patients undergoing cardiac catheterization, to investigate the acute hemodynamic effects of transvenous cardiac autonomic nerve stimulation.
- Trial name
- COAST-HF HNrCS (NCT02880683)
- Testing
- NeuroTronik CANS Therapy System
- Where
- Paraguay
- Volunteers
- 16 people
- Sponsor
- NeuroTronik Inc.
Complications; Cesarean Section, Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Hemodynamic Effects of Low Dose Spinal Anesthesia for Cesarean Section
We propose to study the effects on hemodynamics (blood pressure, cardiac output, and central venous pressure) of two doses of bupivacaine for spinal anesthesia during cesarean section: a higher dose of 12 mg to a lower dose of…
- Conditions
- Complications; Cesarean Section, Effects of; Anesthesia, Spinal and Epidural, in Pregnancy, Hemodynamic Instability, Personal Satisfaction
- Trial name
- NCT02036697
- Testing
- Bupivacaine 4.5, Bupivacaine 9, Morphine
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Low Cardiac Output Syndrome, Cardiogenic Shock
Milrinone Versus Dobutamine in Critically Ill Patients
The investigators are interested in determining if there is a meaningful difference between two of the most commonly used medications used to improve the pumping function of the heart among critically ill patients admitted to the…
- Conditions
- Low Cardiac Output Syndrome, Cardiogenic Shock, Acute Coronary Syndrome, Pulmonary Edema
- Trial name
- NCT03207165
- Testing
- Milrinone, Dobutamine
- Where
- Canada
- Volunteers
- 192 people
- Sponsor
- Ottawa Heart Institute Research Corporation