Clinical trials: Candida Infection
Candidiasis, Oral
Trial of Two Dosing Regimens of Micafungin Versus Caspofungin for the Treatment of Esophageal Candidiasis
To determine the efficacy and safety of daily doses of IV micafungin versus IV caspofungin for the treatment of esophageal candidiasis
- Trial name
- NCT00665639
- Testing
- micafungin, caspofungin
- Where
- 31 sites in Argentina, Brazil and 2 more
- Volunteers
- 454 people
- Sponsor
- Astellas Pharma Inc
Candidiasis, Oral, HIV Infections
Comparative Randomized Study of the Efficacy, Safety, and Toleration of Fluconazole Oral Suspension or Nystatin Oral Suspension in the Treatment of Patients With Oropharyngeal Candidiasis in Association With the Acquired Immunodeficiency Syndrome
To compare the efficacy, safety, and toleration of fluconazole as a single daily oral suspension for 14 days versus nystatin oral suspension 4 times daily for 14 days in the treatment of oropharyngeal candidiasis in patients with…
- Trial name
- NCT00002112
- Testing
- Nystatin, Fluconazole
- Where
- 5 sites in United States
- Sponsor
- Pfizer
Oral Lichen Planus, Recurrent Aphthous Stomatitis
Improving Prescribing Quality for Oral Mucosal Disorders Using a Pharmacist-Led Model
This study aims to improve how oral mucosal disorders-such as oral lichen planus, recurrent aphthous stomatitis, burning mouth syndrome, herpes viral infection and oral candidiasis-are treated in dental settings.
- Conditions
- Oral Lichen Planus, Recurrent Aphthous Stomatitis, Burning Mouth Syndrome, Oral Candidiasis
- Trial name
- NCT07721090
- Testing
- Pharmacist-Led Prescribing Optimization and Patient Counselling
- Volunteers
- 336 people
- Sponsor
- University of Fujairah
Fungal Infection by Site
Outcomes of Patients Who Fail to Respond to Fluconazole Treatment of Severe Candida Albicans Infections
The primary aims of this study are to identify and characterize the immediate consequences of patients who fail fluconazole treatment during the treatment of severe infection, and to determine if fluconazole failures are more…
- Trial name
- NCT00721487
- Testing
- Fluconazole
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- CPL Associates
Vulvovaginal Candidiases
Epidemiological Study in Subjects With Vulvovaginal Candidiases
Epidemiological study about the clinical and microbiological progress in subjects under treatment for a severe vulvovaginal candidiases episody
- Trial name
- NCT03064789
- Where
- Spain
- Volunteers
- 43 people
- Sponsor
- Dr. Santiago Palacios
Oral Candidiasis
Acidophilus for the Treatment and Prevention of Oral Candidiasis in Patients Undergoing Radiation Therapy
The purpose of this study is to determine the effectiveness of using acidophilus to treat oral candidiasis (thrush) caused by radiation therapy to the head and neck region. This study will conducted in two parts.
- Trial name
- NCT00768794
- Testing
- Acidophilus, Acidolphilus
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Summa Health System
Invasive Candidiasis, Invasive Aspergillosis
Amphotericin B Cholesteryl Sulfate Complex for Injection(ABCD) in the Treatment of Invasive Candidiasis and Invasive Aspergillosis
This is an open, multicenter clinical trial of ABCD for invasive candidiasis and invasive aspergillosis.
- Trial name
- NCT04225195
- Testing
- Amphotericin B cholesteryl sulfate complex for injection(ABCD)
- Volunteers
- 60 people
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Candidiasis, Esophageal, HIV Infections
Evaluation of Amphotericin B in the Treatment of Biopsy Proven Candida Esophagitis in Immunocompromised Patients
To determine the appropriate duration of amphotericin B therapy for Candida esophagitis. To compare the effectiveness of two different amphotericin B doses in the treatment of biopsy-proven Candida esophagitis.
- Trial name
- NCT00002041
- Testing
- Amphotericin B
- Where
- United States
- Sponsor
- Bristol-Myers Squibb
Fungal Infections, Primary Immune Deficiencies
Studies of Disorders With Increased Susceptibility to Fungal Infections
Background: Researchers are interested in studying disorders that make individuals more susceptible to fungal infections, specifically infections with the Candida yeast.
- Trial name
- NCT01222741
- Where
- United States
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Candidiasis, Oral, HIV Infections
A Study of Amphotericin B in the Treatment of Fungal Infections of the Mouth in HIV-Infected Patients Who Have Not Had Success With Fluconazole
To assess response and toxicity in patients with fluconazole-resistant oral candidiasis ( thrush ) when given initial induction with amphotericin B oral suspension.
- Trial name
- NCT00001065
- Testing
- Amphotericin B
- Where
- 32 sites in United States, Puerto Rico and 1 more
- Volunteers
- 70 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Candidiasis
Early Clinical Experience With Anidulafungin In Patients With Liver Disease In The United Kingdom
The purpose of this study is to describe the real world effectiveness of anidulafungin in clinical practice in a large Liver Unit in the United Kingdom.
- Trial name
- NCT01202253
- Testing
- anidulafungin
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Pfizer
Vulvovaginal Candidiasis
Monthly Itraconazole Versus Classic Homeopathy for Treatment of Recurrent Vulvovaginal Candidiasis (RVVC)
A prospective study to evaluate the efficacy of classic homeopathic therapy compared to maintenance itraconazole therapy with and without additional exogenous lactobacillus for treatment of recurrent Candida vaginitis.
- Trial name
- NCT00895453
- Testing
- itraconazole, lactobacillus gasseri, classic homeopathy (carcinosin M, nux vomica, pulsatilla M, ferrum metallicum, sepia M, etc. as prescribed)
- Where
- Austria
- Volunteers
- 144 people
- Sponsor
- Medical University of Vienna
Vaginitis
Management of Vaginal Complaints: A Pilot Study Within a Practice-Based Research Network
Many women present in primary care with vaginal complaints. The best way of managing these complaints is unclear. This trial will test two different methods of managing patients with vaginal complaints. This is a pilot trial.
- Trial name
- VCAT (NCT00503542)
- Testing
- Terazol or oral fluconazole for candidal vaginitis, Metronidazole or Clindamycin for Bacterial Vaginosis, Flagyl for definitively diagnosed vaginal trichomoniasis
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Posaconazole, Pharmacokinetics
Posaconazole Pharmacokinetics in Patients Receiving Chemotherapy or Stem Cell Transplants
The purpose of the study is to investigate the pharmacokinetics of oral dosage of Posaconazole which is routinely administered as a standard care prophylaxis for patients undergoing cancer treatments.
- Conditions
- Posaconazole, Pharmacokinetics, Invasive Candidiases, Invasive Aspergillosis
- Trial name
- POPULAR (NCT03717623)
- Testing
- Posaconazole pharmacokinetics
- Where
- Australia
- Volunteers
- 100 people
- Sponsor
- Melbourne Health
Bacterial Vaginosis, Vaginal Candidiasis
Multi-Gyn FemiTotal for the Treatment and Prevention of Vulvovaginal Candidiasis Symptoms and Bacterial Vaginosis
The goal of this clinical trial is to assess the safety and efficacy of Multi-Gyn Femitotal to treat and prevent women suffering from bacterial vaginosis and vulvo vaginal candidiasis.
- Trial name
- NCT07234786
- Testing
- Multi-Gyn FemiTotal
- Where
- Mauritius
- Volunteers
- 80 people
- Sponsor
- Karo Pharma AB
Fungal Infection
Efflux Pump Mediated Azole Resistance in Candida Albicans
Candida albicans is the major fungal pathogen causing infections in humans, ranging from superficial mucosal infection to systemic mycoses.
- Trial name
- NCT03659162
- Testing
- Azole Antifungal
- Volunteers
- 100 people
- Sponsor
- Assiut University
Invasive Candidiasis
Anidulafungin Candidemia/Invasive Candidiasis Intensive Care Study
To evaluate the efficacy and safety of anidulafungin in the treatment of systemic fungal infections in intensive care and critical care unit patients.
- Trial name
- ICE (NCT00689338)
- Testing
- Anidulafungin, Fluconazole, Voriconazole
- Where
- 61 sites in Austria, Belgium and 17 more
- Volunteers
- 216 people
- Sponsor
- Pfizer
Candidiasis
Staging Candidiasis in ICU Patients
Our primary objective is to evaluate the relevance of the early determination of Candida infection status among non-neutropenic patients hospitalized over 48 hours in ICUs.
- Trial name
- NCT01322698
- Testing
- Tests for candidiasis
- Where
- 2 sites in France
- Volunteers
- 422 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Vaginal Diseases
Probiotic for Vaginal Candidiasis in Pregnant Women
This project aims to study the benefits of a probiotic product, STP4 for vaginal health properties, primarily prevention of vaginal candidiasis, among pregnant women in second and third trimester pregnancy.
- Trial name
- NCT03940612
- Testing
- STP4 (product with probiotics)
- Where
- Malaysia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Candidiasis, Esophageal, HIV Infections
A Study of the Side Effects of L-743,872 in Men With Candidal Esophagitis
The purpose of this study is to see if it is safe to give L-743,872 to men with candidal esophagitis, an AIDS-related yeast infection in the esophagus.
- Trial name
- NCT00005921
- Testing
- L-743,872
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Merck Sharp & Dohme LLC