Clinical trials: Cancer Screening
Advanced Solid Tumors, Metastatic Solid Tumors
Master Protocol for Basket Clinical Trials of Targeted Therapies Based on Proteome and Whole Exome Sequencing Screening in Patients With Advanced Solid Tumors
Study Overview This study evaluates a proteogenomic screening platform to identify precise therapeutic targets for patients with advanced solid tumors.
- Conditions
- Advanced Solid Tumors, Metastatic Solid Tumors, Locally Advanced Solid Tumors, Recurrent Solid Tumors
- Trial name
- K-PRECISION (NCT07891169)
- Testing
- Homologous Recombination Deficiency (HRD), ALK/ROS1/MET, standard care treatment
- Where
- 2 sites in South Korea
- Volunteers
- 2,800 people
- Sponsor
- National Cancer Center, Korea
Breast Cancer Screening
Breast Cancer Screening for Underserved Women: Comparing Outcomes and Lowering Recall Rates With 3D- vs. 2D-mammography
Three-dimensional (3D) + two-dimensional (2D)- mammography may have particular value for minority, rural, and underserved women in New Mexico by decreasing recall rates and improving diagnostic sensitivity, thus alleviating some…
- Trial name
- NCT03979729
- Testing
- Routine Screening Mammogram (3D + 2D), Routine Screening Mammogram (2D), No Screening Mammogram
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- New Mexico Cancer Research Alliance
Cervical Cancer Screening, Human Papilloma Virus
Developing and Implementing HPV SCREENED
This study will assess the feasibility of implementing HPV self-sampling as a primary cervical cancer screening strategy for under-screened women in the emergency department (ED).
- Trial name
- NCT07657104
- Testing
- HPV Self-collection in the ED
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Young Adult-Mediated Intervention to Increase Colorectal Cancer Screening
Young Adult-Mediated Intervention to Increase Colorectal Cancer Screening
This study will garner preliminary data to develop a young adult-mediated intervention whereby a younger family member encourages their older family member to get colorectal cancer (CRC) screening.
- Trial name
- NCT05936931
- Testing
- Changes in CRC screening awareness and intentions
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Ovarian Cancer Screening Recommendations by Gynecologists
Ovarian Cancer Screening and AI
Gynecologists frequently overestimate the benefits and safety of ovarian cancer screening. AI-supported discussions may help correct these misperceptions.
- Trial name
- AI-OCS-Gyn (NCT07503054)
- Testing
- ChatGPT - Control, ChatGPT - Evidence-Based Screening Discussion
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- Charite University, Berlin, Germany
Breast Cancer Detection, Breast Cancer
Screening and the Future of Enhanced MRI for Early Breast Cancer Detection
This study aims to recruit women aged 45 years in the Netherlands to participate in a one-time breast MRI screening examination and to evaluate their motivation for participation as well as the impact of screening on their…
- Conditions
- Breast Cancer Detection, Breast Cancer, Screening Strategy
- Trial name
- SAFE-MRI (NCT07878377)
- Testing
- Breast MRI Screening, Questionnaires
- Volunteers
- 2,628 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Breast Cancer Screening, Cervical Cancer Screening
Cancer Awareness Among Syrian Migrants
This study aims to develop and evaluate a theory-based educational intervention to improve cancer screening participation among Syrian migrants in Turkey.
- Conditions
- Breast Cancer Screening, Cervical Cancer Screening, Colorectal Cancer Screening, Cancer Prevention Behavior
- Trial name
- NCT07541105
- Testing
- PMT-Based Cancer Screening Educational Intervention, PMT-Based Cancer Screening Education Program
- Volunteers
- 30 people
- Sponsor
- Toros University
Endometrial Cancer, DNA Methylation
Cervical Cytology DNA Methylation for Endometrial Cancer Screening
This study intends to conduct the "Real-world Study on Cervical Cytology Methylation Testing for Endometrial Cancer Screening" project through a multi-center real-world research approach.
- Conditions
- Endometrial Cancer, DNA Methylation, Cytology, Cancer Screening
- Trial name
- NCT07874529
- Testing
- CDO1 and CELF4 gene methylation
- Where
- China
- Volunteers
- 30,000 people
- Sponsor
- Lei Li
Cervical Cancer Screening
Effectiveness of an eHealth Intervention for Uptake of Cervical Cancer Screening in Hispanic Women
This study will test the effectiveness of an eHealth promotora (lay health advisor) outreach strategy to increase cervical cancer screening in Hispanic women.
- Trial name
- NCT06741241
- Testing
- eHealth Promotora, eHealth Healthy Nutrition
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Florida A&M University
Prostate Cancer Screening
MRI Screening in Men at High Risk of Developing Prostate Cancer
The purpose of this study is to determine whether or not Magnetic Resonance Images (MRI) will identify high-grade cancers earlier and more frequently in men at high risk of developing prostate cancer.
- Trial name
- NCT05608694
- Testing
- Prostate MRI
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- University of Chicago
Lung Cancer Screening
A Study of Lung Cancer Screening in People With Unexplained Weight Loss
The researchers are doing this study to see if people with unexplained weight loss who have lung cancer screening are more likely to have or develop lung cancer than people without unexplained weight loss.
- Trial name
- NCT06717334
- Testing
- Low Dose CT imaging, blood draws, screening questionnaire
- Where
- 8 sites in United States
- Volunteers
- 409 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Colorectal Cancer Screening
Effectiveness of a Cloud-based Digital Health Navigation Program for Colorectal Cancer Screening
mPATH-CRC (mobile Patient Technology for Health) is an automated direct-to-patient digital health program about colorectal cancer screening.
- Trial name
- NCT06821009
- Testing
- mPATH-CRC, Usual Care (Control)
- Where
- 2 sites in United States
- Volunteers
- 6,500 people, healthy volunteers welcome
- Sponsor
- Digital Health Navigation Solutions, Inc
Anxiety, Cervical Cancer Screening
Cervical Cancer Awareness Education to Aid Confidence and Screening upTake (ACT): A Pilot Randomised Control Trial
Cervical cancer remains a major threat to women's health and wellbeing, with the burden disproportionately concentrated in low- and middle-income countries such as Nigeria, where inadequate awareness, limited access to screening…
- Conditions
- Anxiety, Cervical Cancer Screening, Health Education, Wellbeing
- Trial name
- ACT (NCT07863596)
- Testing
- cervical cancer Awareness education to aid Confidence and screening upTake (ACT), Control group
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Teesside University
Lung Cancer Screening, Military Service-related Environmental and Occupational Exposures
Personalizing Veterans' Lung Cancer Screening and Diagnosis
Lung cancer screening with low-dose chest computed tomography (CT) is currently recommended for high-risk individuals who are 50 to 80 years old, have smoked cigarettes for at least 20 pack-years, and currently smoke or quit…
- Conditions
- Lung Cancer Screening, Military Service-related Environmental and Occupational Exposures, Cancer Survivor, Family History of Lung Cancer
- Trial name
- MAS-EXPAND (NCT07838519)
- Testing
- Low-dose computed tomography
- Where
- 7 sites in United States
- Volunteers
- 1,400 people
- Sponsor
- VA Office of Research and Development
Cervical Cancer Screening, Cervical Cancer
Culturally Adapted Materials to Increase Cervical Cancer Screening Among Polish Women in Iceland
This study tests whether sending Polish women residing in Iceland a culturally adapted invitation letter - tailored in language and messaging to the target group - increases participation in cervical cancer screening compared…
- Conditions
- Cervical Cancer Screening, Cervical Cancer, Cervical Cancer (Early Detection)
- Trial name
- NCT07856862
- Testing
- Culturally adapted cervical cancer screening invitation letter, Standard cervical cancer screening invitation letter
- Where
- Iceland
- Volunteers
- 2,000 people
- Sponsor
- The Primary Health Care in the Capital Area
Sickle Cell, Diabetes
Developing the Family Map: Looking at Communal Coping
Background: Knowing one s family medical history is a part of staying healthy. Some health risks run in families, and knowing these risks can promote more healthy behavior.
- Conditions
- Sickle Cell, Diabetes, Cancer, Cardiovascular Disease
- Trial name
- NCT01633021
- Where
- 3 sites in United States
- Volunteers
- 1,061 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Colorectal Neoplasms, Mass Screening
Preventing Early-Onset Colorectal Cancer in the VA
Colorectal cancer is a leading cause of cancer death among Veterans. The starting age for colorectal cancer screening has been lowered from 50 to 45 years in response to the rising incidence of early-onset colorectal cancer…
- Trial name
- PRECISE (NCT07071454)
- Testing
- Patient intervention, PCP intervention
- Where
- United States
- Volunteers
- 536 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cervical Cancer Screening, HPV Infection
Risk of Cervical Cancer Following Incident, Persistent and History-unknown HPV Detection
The goal of this register-based retrospective observational study is to understand the risk of cervical cancer following incident, persistent and history-unknown HPV detection by HPV genotype in healthy women participating in…
- Trial name
- NCT07850128
- Testing
- No Intervention: Observational Cohort
- Where
- Sweden
- Volunteers
- 130,000 people
- Sponsor
- Karolinska Institutet
Colorectal Cancer Screening
Optimizing Participation In Colorectal Cancer Screening By Direct Invitation Of Non Responders By General Practitionners
The goal of this randomized trial is to assess the effectiveness of a targeted telephone reminder strategy, implemented by the patient's general practitioner, in enhancing participation in colorectal cancer screening among…
- Trial name
- OPTIDEC COLO (NCT07639554)
- Testing
- Intervention
- Where
- France
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- MSPU des 3 Provinces
Colorectal Cancer (CRC) Screening
A Novel Multi-functional Artificial Intelligence System on Treatment Efficacy and Implementation in Colonoscopy
To overcome non-neoplastic polyp (NNP) resections, computer-aided diagnosis (CADx) systems have been developed. In a meta-analysis, the performance of CADx systems was superior to endoscopists.
- Trial name
- mAInstream (NCT07844252)
- Testing
- CADe/CADx
- Volunteers
- 2,818 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong