Clinical trials: Calorie Restriction
Overweight
Effect of South Beach Diet (SBD™) Using SBD™ Products Compared to a Calorie-Restricted Diet in Women
The purpose of this study is to examine the effectiveness of the South Beach Diet™ and South Beach Diet™ products compared to a traditional calorie restricted diet.
- Trial name
- NCT00932516
- Testing
- South Beach Diet™ with South Beach Diet™ Products, South Beach Diet™, Calorie restricted diet with South Beach Diet™ Products
- Where
- 4 sites in United States
- Volunteers
- 248 people
- Sponsor
- Mondelēz International, Inc.
Time Restricted Eating, Obesity
Time-restricted Eating Versus Daily Continuous Calorie Restriction on Body Weight and Colorectal Cancer Risk Markers
Approximately 42% of American adults are obese, and this condition is strongly related to the development of colorectal cancer. Innovative lifestyle strategies to treat obesity and reduce colorectal cancer risk are critically…
- Conditions
- Time Restricted Eating, Obesity, Weight Loss, Colorectal Cancer
- Trial name
- NCT05114798
- Testing
- Time restricted eating, Calorie Restriction
- Where
- United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Overweight, Obese
Effects of Long Term Calorie Restriction on Sphingomyelin and Amino Acids
The effect of weight loss with long-term low calorie diet (LCD) on plasma metabolites is unknown. The aim was to examine whether a LCD-induced weight reduction results in changes in the extended plasma metabolites.
- Trial name
- NCT02081898
- Testing
- LCD
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Yonsei University
Obesity, Type 2 Diabetes Mellitus
Changes in Insulin Sensitivity After Weight Loss
This study is designed to compare the changes in insulin sensitivity as well as gastrointestinal hormone levels in diabetic and non-diabetic obese individuals who are undergoing weight loss procedures.
- Conditions
- Obesity, Type 2 Diabetes Mellitus, Insulin Resistance
- Trial name
- NCT00627484
- Testing
- Gastric bypass, Gastric banding, Sleeve gastrectomy
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Columbia University
Inflammation
Effects of a Short Term Caloric Restriction on T Cell Activation in Fat
Overweight and obesity are major problems and their complications such as cardiovascular disease and type 2 diabetes mellitus pose great burdens on healthcare systems.
- Trial name
- NCT02473835
- Testing
- Calorie restriction, Activity monitoring, Diet monitoring
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Bath
Multiple Sclerosis
Calorie Restriction in Multiple Sclerosis Patients
The investigators hypothesize that adipokine (soluble molecules produced by the adipose tissue) levels are altered in MS compared to control subjects.
- Trial name
- NCT02411838
- Testing
- Calorie restriction
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Washington University School of Medicine
Anorexia in Adolescence, Anorexia Nervosa
3-Dimensional Optical Scanning to Assess and Monitor Malnutrition in Eating Disorders (3D-ED) Study
People with anorexia nervosa often become medically unstable because of severe malnutrition and require hospitalization for nutritional rehabilitation.
- Conditions
- Anorexia in Adolescence, Anorexia Nervosa, Anorexia Nervosa, Atypical, Anorexia Nervosa, Binge Eating/Purging Type
- Trial name
- 3D-ED (NCT07726524)
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of California, San Francisco
Hypertriglyceridemia, Overweight or Obesity
Intermittent Fasting in Hypertriglyceridemic Overweight or Obese Subjects
some studies have shown similar effects of intermittent fasting and continuous caloric restriction on body weight and plasma lipid profile, but there is still a wide controversy.
- Trial name
- NCT04143971
- Testing
- intermittent fasting diet, low calorie diet
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Shahid Beheshti University
Acute Renal Failure
Brief Title:Effect of a Preoperative Calorie Restriction on Renal Function After Cardiac Surgery
The aim of this study is to assess the effect of a diet prior to cardiac surgery on the common postoperative decline of renal function. Until now, there is no known drug or procedure to preserve the kidneys from this impairment.
- Trial name
- CR_KCH (NCT01534364)
- Testing
- calorie restriction
- Where
- Germany
- Volunteers
- 82 people
- Sponsor
- University of Cologne
Obesity, Menopause
Calorie Restriction With Leucine Supplementation
The purpose of this study is to determine whether consuming additional leucine during calorie restriction induced weight loss has beneficial or harmful effects on multi-organ (liver, muscle, adipose tissue) insulin sensitivity…
- Conditions
- Obesity, Menopause, Osteoporosis, Sarcopenia
- Trial name
- NCT01757340
- Testing
- Weight loss with normal protein and leucine intake, Weight loss with protein/leucine supplementation
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Calorie Restriction
The CALERIE™ Legacy Study
The purpose of the CALERIE Legacy Study is to follow up on the health and wellness of participants from phase 2 of the Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy (CALERIE) trial, which was…
- Trial name
- NCT05651620
- Where
- 3 sites in United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Tufts University
Morbid Obesity, Liver Fat
Low-calorie Diet and Body Composition Prior to Roux-en-Y Gastric Bypass
Losing weight before undergoing Roux-en-Y gastric bypass (RYGB) surgery may reduce liver fat content and size thereby improving surgical outcomes.
- Trial name
- LCD (NCT02144597)
- Testing
- Liquid formula low-calorie diet (LCD), Roux-en-Y gastric bypass (RYGB), Control diet
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Imperial College London
Excessive Diet Restriction
How Participants Behave and Respond on Their Own After Completing a 2-year Intervention of Calorie Restriction
The purpose of this study is to gain knowledge about how participants behave and respond on their own after completing a 2-year intervention of calorie restriction.
- Trial name
- CALERIE2-FU (NCT00943215)
- Volunteers
- 42 people
- Sponsor
- Pennington Biomedical Research Center
Eating Disorders, Intermittent Fasting
Effect of Fasting and Calorie-Restricted Diets on Dopamine and Serotonin Levels Among Obese Women With BED and FA
Obesity presents a substantial economic burden in Jordan. Binge eating disorder (BED) and food addiction (FA) are the most common eating disorders associated with obesity.
- Conditions
- Eating Disorders, Intermittent Fasting, Obesity
- Trial name
- NCT04873648
- Testing
- caloric reduced -intermitted fasting diet, Daily calorie restriction, Control group
- Where
- Jordan
- Volunteers
- 100 people
- Sponsor
- University of Jordan
Obesity Type 2 Diabetes Mellitus
Fecal Microbiota Transplantation (FMT) Combined With Calorie-Restricted Diet and Semaglutide in Patients With Obesity and Type 2 Diabetes
Investigation of the efficacy of fecal microbiota transplantation added to calorie-restricted diet and semaglutide versus calorie-restricted diet and semaglutide alone for weight loss and metabolic improvement in patients with…
- Trial name
- NCT07599046
- Testing
- Fecal microbiota transplantation (FMT), Semaglutide (1 Mg Dose), Calorie-restricted diet
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Eighth Affiliated Hospital, Sun Yat-sen University
Nonalcoholic Fatty Liver, Nonalcoholic Steatohepatitis
Nonalcoholic Fatty Liver Disease - Intermittent Calorie Restriction (FLICR) Study
Several diets have been proposed to reduce liver steatosis in patients with nonalcoholic fatty liver disease (NAFLD), and various effects on liver steatosis have been observed.
- Trial name
- NCT05309642
- Testing
- Intermittent calorie restriction, Standard of care
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Ewha Womans University Mokdong Hospital
Obesity
A Study to Measure Calorie Consumption and Usage in Participants With Obesity Using LY3437943
The main purpose of the study is to look at the effect of the study drug compared to placebo on calorie intake, energy metabolism, and appetite. The study will last up to 6 months and may include up to 20 visits.
- Trial name
- NCT06313528
- Testing
- LY3437943
- Where
- 3 sites in United States
- Volunteers
- 85 people
- Sponsor
- Eli Lilly and Company
Obesity, Menopause
Calorie Restriction, Protein Supplementation and Metabolic Health
The purpose of this study is to determine whether consuming additional protein during calorie restriction induced weight loss has beneficial or harmful effects on multi-organ (liver, muscle, adipose tissue) insulin sensitivity…
- Conditions
- Obesity, Menopause, Osteoporosis, Sarcopenia
- Trial name
- CRPS (NCT01538836)
- Testing
- Weight loss with normal protein intake, Weight loss with protein supplementation
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obesity
Brain Response to Dietary Interventions
In order to better understand how commonly used dietary interventions for obesity influence brain activity and in turn people's ability to adhere to their healthy nutrition plan, the investigators need to study how people's…
- Trial name
- BRDI (NCT02637271)
- Testing
- Low calorie total meal replacement, Low calorie typical diet
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Texas Tech University
Obesity, Severe Obesity
Energy Expenditure From ECAL Indirect Calorimeter in a Multicomponent Weight Management Service
Whether greater weight loss is as a result of a smaller reduction in energy expenditure with caloric restriction is not known. Resting energy expenditure and 24-hour energy expenditure vary substantially between individuals.
- Conditions
- Obesity, Severe Obesity, Sleep Apnoea
- Trial name
- ECAL (NCT03638895)
- Testing
- ECAL Indirect Calorimeter, Diet, exercise & behaviour modification therapy
- Where
- United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Liverpool