Clinical trials: Caloric Intake and Energy Metabolism
Obesity
Effects of Consuming Protein Shakes, Varying in Protein Source, on Appetite, Satiety and Energy Intake
Background: Consistent data from acute, single preload studies demonstrate improvements in perceived appetite and satiety following the consumption of high-protein preloads compared to normal protein preloads.
- Trial name
- NCT03132376
- Testing
- Water Preload Drink, Whey Protein Isolate Drink, Micellar Casein Protein Drink
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Purdue University
Obesity, Eating Behavior
Portion Size and To-go Container on Dinner Intake
This study investigated whether the provision of a to-go container influenced the portion size effect at a meal. Following a screening visit, women came to the lab once a week for 4 weeks to eat a meal of multiple foods.
- Trial name
- NCT03502096
- Testing
- To-Go container, Control
- Volunteers
- 58 people
- Sponsor
- Penn State University
Obesity
Functional Lipids and Appetite Regulation
To evaluate the short-term effects of structured lipids on appetite regulation.
- Trial name
- NCT00259259
- Testing
- SALATRIM
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Body Weight
Beverage Consumption and Fine Motor Control
The aim of this study will be to compare the effects of daily consumption of aspartame, rebaudioside a, saccharin, sucralose, and sucrose on body weight and composition in a standardized protocol.
- Trial name
- LCS (NCT02928653)
- Testing
- Beverage
- Where
- United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Purdue University
Food Selection, Obesity
Changing Portion Size Descriptions in a Cafeteria
The goal of this this intervention is to test the degree to which a portion size labeling intervention influences consumer selection of smaller portions at two large cafés.
- Conditions
- Food Selection, Obesity, Weight Gain, Food Preferences
- Trial name
- NCT06263621
- Testing
- Intervention "Standard"
- Where
- 2 sites in United States
- Volunteers
- 101,481 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Obesity & Overweight, Healthcare Worker
Personalized Nutrition Coaching for a Weight Loss Program Among Overweight and Obese Nurses
Obesity among healthcare workers has become an increasing public health concern, with potential consequences for work productivity, quality of care, and long-term health outcomes.
- Conditions
- Obesity & Overweight, Healthcare Worker, Low Physical Activity Level
- Trial name
- NCT07440979
- Testing
- Personalized Nutrition Coaching
- Where
- Indonesia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Obesity
The TREND Study: Tapered Reduction in Energy Intake as a Novel Approach to Dieting
TREND is a pilot randomized trial comparing two alternative methods of initiating a low-calorie weight loss diet. The study will compare the traditional diet initiation of abruptly dropping energy intake to 1000 kcal/day for…
- Trial name
- TREND (NCT02837211)
- Testing
- Tapered Low Calorie Diet, Traditional Low-Calorie Diet
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Wake Forest University Health Sciences
Sleep
The Sleep Lengthening and Metabolic Health, Body Composition, Energy Balance and Cardiovascular Risk Study
Short sleep duration has been associated with increased risk of weight gain and development of non-communicable diseases. Sleep deprivation studies have suggested the link between restricted sleep and risk of adiposity and…
- Trial name
- SLuMBER (NCT02787577)
- Testing
- Sleep Lengthening
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- King's College London
Health, Appetite Regulation
Sodium Alginate in Chocolate Milk, Satiety and Glycemic Control
This study compares the effects of isovolumetric (325 ml) preloads of chocolate milk supplemented with sodium alginates at incremental doses on inter-meal glucose levels, appetite scores and food intake in healthy adult men.
- Conditions
- Health, Appetite Regulation, Glucose Metabolism
- Trial name
- NCT01877460
- Testing
- Dietary intervention
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy Underweight, Normal Weight Adults
Energy Metabolism and Eating Behavior in Underweight and Normal-weight Individuals
This study evaluates eating behavior and metabolic responses following consumption of a high-fat high-energy meal in healthy underweight and normal-weight adults.
- Trial name
- PROB I (NCT07671105)
- Testing
- High-fat high-energy meal
- Where
- Chile
- Volunteers
- 59 people
- Sponsor
- Jose Galgani
Schizophrenia, Schizoaffective Disorder
Effects of Antipsychotic Medications on Energy Intake and Expenditure
Aim 1: To evaluate the effect of antipsychotic treatment group on Activity Energy Expenditure. The project hypothesizes that subjects treated with olanzapine will demonstrate a greater decrease in AEE over time than subjects…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Weight Gain
- Trial name
- DLW (NCT00836251)
- Testing
- H218O and 2H2O, administered as a mixed cocktail
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Washington University School of Medicine
Obesity
High Quality Protein for Assisting With Weight Loss
The purpose of this study is to determine if, in presence of a reduced calorie diet, a breakfast containing high quality protein source (eggs) would be more effective in reducing hunger and increasing feeling of fullness compared…
- Trial name
- Egg_breakfast (NCT03085511)
- Testing
- Egg breakfast (EB), Weight Loss Counseling, Weight Loss Diet
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Mitochondrial Diseases, Mitochondrial Myopathies
Human Mitochondrial Stress-driven Obesity Resistance
The overarching aim of this observational study is to determine alterations in energy balance while exploring the underlying cellular mechanisms in human genetic models of mitochondrial stress.
- Conditions
- Mitochondrial Diseases, Mitochondrial Myopathies, Mitochondrial Disorder
- Trial name
- MITO-OB-RES (NCT06080568)
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Total Caloric Intake, Nutrient Dense Caloric Intake
The Presence of Friends Increases Food Intake in Youth
Participants will be matched with either their friend or an unfamiliar peer who is the same gender and about the same age. Participants will have 45 minutes of free-play in an experimental room where they will have free access to…
- Conditions
- Total Caloric Intake, Nutrient Dense Caloric Intake, Energy Dense Caloric Intake
- Trial name
- NCT00874055
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University at Buffalo
Obesity, Eating Behavior
Influence of a Monopoly Game on Subtle Behaviors
This project will investigate the influence of experimentally manipulated perceived social standing on eating behavior and obesity risk.
- Trial name
- NCT02470949
- Testing
- Low Social Status, High Social Status
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Type 2 Diabetes Mellitus, Cardiovascular Disease
The Impact of Reformulated Foods on Cardiovascular Risk Factors
Specific policies on obesity reduction often include a recommendation to reduce sugar consumption as a means of lowering overall caloric intake. Reformulating processed foods (e.g.
- Conditions
- Type 2 Diabetes Mellitus, Cardiovascular Disease, Obesity
- Trial name
- REFORM (NCT01645995)
- Testing
- Reformulated products, Conventional products
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Reading
Obesity
Reducing Dietary Energy Density by Incorporating Vegetables in Order to Decrease Energy Intake
This study will test the hypothesis that incorporating vegetables into meals as a method of reducing the energy density will result in increased vegetable intake and decreased energy intake.
- Trial name
- NCT01165086
- Testing
- Incorporating vegetables into the diet to reduce energy density
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Penn State University
Overweight, Obesity
The Effectiveness of Low Calorie Low Salt Lunch for Weight Reduction of Workers of a Health Promoting Hospital
The aim of this study is to evaluate the effectiveness of Low Calorie Low Salt Lunch for Weight Reduction in overweight or obese workers of a health promoting hospital.
- Trial name
- HPH (NCT02416544)
- Testing
- Lunch which is calorie-restricted and low-salt
- Where
- South Korea
- Volunteers
- 109 people
- Sponsor
- Seoul National University Hospital
Obesity
APPETITE: linguAl PYY3-36 on aPpEtite and acuTe Energy InTakE
A double-blind, cross-over, placebo-controlled, proof-of-concept study using oral peptide YY3-36 solution to investigate the mechanistic role of lingual PYY in regulating appetite, energy intake and food preference in people with…
- Trial name
- APPETITE (NCT05110664)
- Testing
- PYY (3-36) Peptide, Placibo
- Volunteers
- 40 people
- Sponsor
- University College, London
Obesity
A Research Study to Look at How CagriSema Influences Food Intake, Appetite and Emptying of the Stomach in People With Excess Body Weight
This research study tests if CagriSema influences food intake, appetite and emptying of the stomach in people with excess body weight.
- Trial name
- NCT06207877
- Testing
- Cagrilintide, Semaglutide
- Where
- Germany
- Volunteers
- 62 people
- Sponsor
- Novo Nordisk A/S