Clinical trials: Callus
Nutritional Deficiency
Absorption of Zinc (Zn) From Zn-biofortified and Zn-fortified Maize in Young Zambian Children Between 24-36 Months
The objective of this study is to compare the quantity of Zn absorbed from an accurately weighed quantity (~100 g) of minimally milled control maize (~15 µg Zn/g maize), from biofortified maize (~30 µg Zn/g) and from the same…
- Trial name
- HPZM (NCT02208635)
- Testing
- Biofortified Maize, Fortified Maize, Control Maize
- Where
- 2 sites in United States, Zambia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Pseudarthrosis, Ununited Fracture
Tuebingen Register of Union Failure After Fractures of the Upper and Lower Extremities
TRUFFLE is a register of clinical patient data of failed bone healing and bone non-union after fracture. All patients suffering from a long bone delayed or non-union after fracture and undergoing revision surgery are registered…
- Trial name
- TRUFFLE (NCT06098157)
- Where
- Germany
- Volunteers
- 850 people
- Sponsor
- Department of Trauma and Reconstructive Surgery at Eberhard Karls University Tuebingen, BG Klinik Tu
Conduct Disorder, Conduct Disorders in Children
Impact VR: An Emotion Recognition and Regulation Training Program for Youth With CD
Conduct disorder (CD) is one of the most prevalent childhood psychiatric disorders. Unfortunately, there are limited treatments available for CD.
- Conditions
- Conduct Disorder, Conduct Disorders in Children, Conduct Disorders in Adolescence, Callous-Unemotional Traits
- Trial name
- NCT06301516
- Testing
- Virtual Reality, Comparative Control
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Virginia Commonwealth University
Glycemic Index, Glycemic Load
Determination of the Glycemic Index of Products Varying in Levels of Refined and Whole Grain Corn
Interest in identifying low GI foods and the food factors responsible for the low GI of foods has increased. Three corn products with varying levels of refined and whole grain corn will be compared to each other and to a dextrose…
- Trial name
- NCT07427654
- Testing
- Corn snack containing 25 grams available carbohydrate, Dextrose control
- Where
- Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Femur Shaft Fracture, Tibia Fractures
Assessing Bone Fracture Healing Effect of Almonds
Femur and tibia shaft fractures are common after trauma with a burden of 5% and 20% respectively. Clinicians recommend costly bone strengthening drugs/supplements while treating bone fractures.
- Conditions
- Femur Shaft Fracture, Tibia Fractures, Vitamin D, Sweet Almonds
- Trial name
- AFHEA (NCT07153302)
- Testing
- Prunus dulcis (sweet almonds)
- Where
- Pakistan
- Volunteers
- 136 people
- Sponsor
- Aga Khan University Hospital, Pakistan
Diabetic Neuropathies, Plantar Callus
Short-term Effect of Podiatric Callus Debridement on Plantar Pressure in Diabetic Neuropathic Patients
Diabetes peripheral neuropathy (DPN) affects up to 50% of the diabetes population. In the diabetic neuropathic foot, it commonly manifests as loss of protective sensation, foot deformity and skin dryness.
- Trial name
- NCT06357884
- Testing
- Callus debridement
- Where
- Hong Kong
- Volunteers
- 16 people
- Sponsor
- Chinese University of Hong Kong
Vitamin A Status With Maize Feeding
Determination of Changes in Total Body Stores of Vitamin A in Response to Orange Maize Consumption by Zambian Children
Determination of liver stores of vitamin A will be determined before and after consumption of high pro-vitamin A orange maize, compared to low provitamin A white maize.
- Trial name
- NCT01814891
- Testing
- Orange maize feeding, Vitamin A supplement, Oil only
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Age Macular Degeneration
Study of the Macular Pigment by the Consumption of Corn With Strong Content in Zeaxanthine
The Age Macular Degeneration (AMD) is the first cause of blindness in industrialized countries. The macular pigment (lutein and zeaxanthin) could play an important role in the arisen of the AMD.
- Trial name
- MAIS (NCT02113254)
- Testing
- Corn zeaxanthin
- Where
- France
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Diabetic Foot, Diabetic Foot Ulcer
Digital Foot Check by Using the D-Foot, a New Software
Patients with diabetes should be thoroughly examined before they are provided with insoles and shoes. In the study the feet are examined with the help of a new software, the D-Foot. D-Foot includes questions and surveys.
- Conditions
- Diabetic Foot, Diabetic Foot Ulcer, Diabetic Foot Ulcer Neuropathic, Neuropathy;Peripheral
- Trial name
- D-Foot2019 (NCT04054804)
- Testing
- D-Foot
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Sahlgrenska University Hospital
Obesity, Morbid
Plantar Callosities and the Validity of Body Composition Assessment by Bio-impedance in Severely Obese Persons
Studies have confirmed the association between plantar callosities and severely obese individuals. Bioelectrical impedance analysis (BIA) is an increasingly popular tool for estimating body composition because it is easy to use…
- Trial name
- NCT01676883
- Testing
- Bioelectric impedance, Air displacement plethysmography
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Norwegian University of Science and Technology
Keratosis Plantaris
Treatment of Plantar Keratosis With Medicinal Plant in Diabetic Patients
This study evaluates the addition of medicinal plant in the treatment of diabetic foot keratosis. Half of participants will receive medicinal plant and other half will receive a placebo.
- Trial name
- NCT03447925
- Testing
- Medicinal Plant, Salicylate, Vaseline
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Sapucai
Septo-Optic Dysplasia, Agenesis of Corpus Callosum
Sleep Profile of Patients With Septo-optic Dysplasia
The aim of this study is to evaluate sleep of patients with septo-optic dysplasia compared to patients with an isolated disorder of peripheral visual system and patients with corpus callosum agenesis since both visus defict and…
- Conditions
- Septo-Optic Dysplasia, Agenesis of Corpus Callosum, Blindness
- Trial name
- NCT06262152
- Testing
- Actigraphy, blood and salivary sample, and sleep evaluation
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Keratosis, Actinic, Actinic Lesion
A Pre-market Study to Evaluate the Performance and Safety of a Skin Preparation Device for Removal of Dry Crusty Skin
In this clinical one-site investigation the performance and safety of a skin preparation device will be evaluated for removing hyperkeratotic skin prior to further medical treatment.
- Conditions
- Keratosis, Actinic, Actinic Lesion, Solar Keratosis/Sunburn, Hyperkeratosis
- Trial name
- NCT05356572
- Testing
- Investigational Skin Preparation Device, GMDN 47102 / Electrode Skin Abrasive Pad, UMDNS 13-230 / Biopsy punch (Dermal Curette)
- Where
- Finland
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mirka Ltd
Heloma Durum
A 3 Day In-use Assessment of the Scholl Corn Foam Cushions on Pain Levels Associated With Heloma Durum.
This is an open-label, single-centre, parallel-group clinical investigation to evaluate the symptomatic pain relief, consumer acceptability and in-use tolerability of the Scholl Corn Foam Cushion in participants suffering from…
- Trial name
- NCT04695873
- Testing
- Corn Foam Cushion
- Where
- Ireland
- Volunteers
- 96 people
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Leg Length Inequality
Distraction Osteogenesis in Limb-length Discrepancy With Mesenchymal Cell Transplantation
Limb-length discrepancy can be due to many causes. These are divided into three groups: congenital (from birth), developmental (from a childhood disease or injury that slows or damages the growth plates), and posttraumatic (from…
- Trial name
- NCT01210950
- Testing
- cell and RPR injection
- Where
- Iran
- Volunteers
- 6 people
- Sponsor
- Royan Institute
Forefoot Callus, Podiatry
A Longitudinal Quantitative Assessment of the Effectiveness of Metatarsal Pads on Plantar Pressures
Musculoskeletal deformities of the foot and abnormal biomechanics can create areas of high pressure over bony prominences on the plantar aspect of the foot and often lead to the formation of calluses and corns.
- Conditions
- Forefoot Callus, Podiatry, Foot Dermatoses, Keratosis
- Trial name
- NCT04336514
- Testing
- Semi-compressed felt pad (SCF)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Nutritional Deficiency
Zinc Bioavailability From Amaranth-enriched Maize Tortillas
Young children in Guatemala are at risk for nutrient deficiencies due to plant-based diets and poor sanitation. Stunting, frequent diarrhea, and respiratory infections are common.
- Trial name
- NCT02208609
- Testing
- Day 1: Maize Tortillas with 20% Amaranth, Day 2 Maize Tortillas without 20% Amaranth
- Where
- 2 sites in United States, Guatemala
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Foot Callus, Plantar Fascitis
Talocalcaneal Angle in Calcaneal Spur Formation
Calcaneal spur is one of the most common causes of chronic heel lower face pain without a traumatic cause. Obesity, sedentary life and advanced age play a role in its etiology.
- Trial name
- NCT05509556
- Testing
- talocalcaneal angle measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Healthy
A Study to Examine the Glycemic Response of Corn and Soy Tortillas in Healthy Individuals
Tortillas are a staple food in several cultures and are widely used to make tacos, burritos, and enchiladas. These foods are gaining a significant segment of the North American fast food and restaurant industry.
- Trial name
- SOYT-2013 (NCT01828671)
- Testing
- Oral Glucose Solution 296 mls, Corn Tortilla, Low Soy Flour Corn Tortilla
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Affective Symptoms, Empathy
Facial Affect Sensitivity Training for Young Children With Callous-unemotional Traits
The goal of this study is to test a novel intervention for children ages 6-11 with elevated callous-unemotional (CU) traits. Conduct problems are among the most prevalent and costly mental health conditions of childhood, and a…
- Trial name
- NCT04159168
- Testing
- Facial Affect Sensitivity Training (FAST), Implicit Gaze Training task (Active control condition)
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- University of Alabama, Tuscaloosa