Clinical trials: Calciphylaxis, open to volunteers
Calciphylaxis
Anti-Interleukin-6 (IL6) in Calciphylaxis
Calciphylaxis is a rare but incredibly dangerous condition that causes small blood vessels in the skin to become blocked by calcium buildup and blood clots. This leads to painful skin sores (necrosis) that do not heal easily.
- Trial name
- NCT07708038
- Testing
- Tocilizumab
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Boston Medical Center
Diabetic Foot, Pressure Ulcer
A Real-World Registry of Chronic Wounds and Ulcers
WOUNDJOURNEY is a longitudinal, real-world, observational registry designed to capture the full clinical course and patient journey associated with chronic wounds and ulcers.
- Conditions
- Diabetic Foot, Pressure Ulcer, Surgical Wound Dehiscence, Vasculitis
- Trial name
- WOUNDJOURNEY (NCT02280733)
- Testing
- Usual care
- Where
- United States
- Volunteers
- 300,000 people
- Sponsor
- U.S. Wound Registry
Calciphylaxis, Calcific Uremic Arteriolopathy
Partners Calciphylaxis Biobank
Calciphylaxis, a vascular calcification disorder, is a rare and serious disorder characterized by calcification of dermal arterioles.
- Conditions
- Calciphylaxis, Calcific Uremic Arteriolopathy, End Stage Renal Disease, Chronic Kidney Diseases
- Trial name
- PCB (NCT03032835)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Massachusetts General Hospital
Calciphylaxis
Study of EPN-701 for the Treatment of Calciphylaxis
Calciphylaxis is a rare but serious condition that leads to painful skin lesions. At present, there is no approved treatment for calciphylaxis.
- Trial name
- NCT07583745
- Testing
- EPN-701 (Oral)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Sagar U. Nigwekar, MD, MMSc
Chronic Kidney Diseases, Calciphylaxis
Human Amniotic-Derived Mesenchymal Stem Cell Therapy for Calciphylaxis
Treatment for Calciphylaxis Patients with Human Amniotic-derived Mesenchymal Stem Cells
- Conditions
- Chronic Kidney Diseases, Calciphylaxis, Calcific Uremic Arteriolopathy, Treatment
- Trial name
- NCT04592640
- Testing
- Human amniotic-derived mesenchymal stem cells
- Where
- China
- Volunteers
- 9 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Calciphylaxis, Calcific Uremic Arteriolopathy
Calciphylaxis in Patients With Chronic Kidney Disease - A Study of the Danish Calciphylaxis Research Initiative (DanCaRI)
Calciphylaxis is a rare yet life-threatening condition involving pronounced calcification in small blood vessels of the skin. Knowledge about its underlying mechanisms and contributing risk factors remains limited.
- Conditions
- Calciphylaxis, Calcific Uremic Arteriolopathy, End Stage Renal Disease (ESRD), Chronic Kidney Diseases
- Trial name
- NCT07511283
- Where
- Denmark
- Volunteers
- 860 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Calciphylaxis
Better Evidence and Translation for Calciphylaxis
This global platform study will evaluate multiple interventions, across several domains of therapeutic care, in adult patients with kidney failure and newly diagnosed calciphylaxis.
- Trial name
- BEAT-Calci (NCT05018221)
- Testing
- Vitamin K1, Magnesium citrate, Sodium Thiosulfate
- Where
- 21 sites in Australia, New Zealand
- Volunteers
- 350 people
- Sponsor
- University of Sydney
Metabolic Disorder, End Stage Renal Disease
Rheopheresis as Adjuvant Treatment of Calciphylaxis
The investigators propose to set up a prospective randomized controlled trial to control the security and assess the efficacy of adjuvant treatment by rheopheresis in necrotizing-ulcered calciphylaxis in the hemodialysis…
- Conditions
- Metabolic Disorder, End Stage Renal Disease, Rare Diseases
- Trial name
- RHEO-CAL (NCT04654000)
- Testing
- Rheopheresis procedure
- Where
- 29 sites in France
- Volunteers
- 138 people
- Sponsor
- University Hospital, Lille
Adenine Phosphoribosyltransferase Deficiency, AH Amyloidosis
National Registry of Rare Kidney Diseases
The goal of this National Registry is to is to collect information from patients with rare kidney diseases, so that it that can be used for research.
- Conditions
- Adenine Phosphoribosyltransferase Deficiency, AH Amyloidosis, AHL Amyloidosis, AL Amyloidosis
- Trial name
- RaDaR (NCT06065852)
- Where
- United Kingdom
- Volunteers
- 35,000 people
- Sponsor
- UK Kidney Association