Clinical trials: Caesarean Sections, open to volunteers
Shivering, Post-Spinal Shivering
Efficacy of Intravenous Midazolam-Ketamine Combination Versus Placebo for Prevention of Post-Spinal Shivering in Elective Cesarean Section
Spinal anesthesia is the preferred anesthetic method for elective cesarean deliveries, but it frequently causes post-spinal shivering.
- Conditions
- Shivering, Post-Spinal Shivering, Hypothermia, Cesarean Section
- Trial name
- NCT07855523
- Testing
- Midazolam and Ketamine, 0.9% Sodium Chloride
- Volunteers
- 120 people
- Sponsor
- Assiut University
Postoperative Pain After Cesarean Section
TAP vs. ESP Blocks for Post-Cesarean Analgesia
This study compares the effectiveness of two ultrasound-guided nerve blocks (TAP block and ESP block) versus standard pain management for relieving pain after a planned cesarean section.
- Trial name
- RCT-TAP-ESP-CS (NCT07853482)
- Testing
- Ropivacaine, Ultrasound-guided Nerve Block, Ketoprofen and Paracetamol
- Where
- Russia
- Volunteers
- 162 people
- Sponsor
- Maternity Hospital - State Budgetary Institution of the Rostov Region, Taganrog
Cesarean Section Complications
Ultrasonographic ONSD as a Predictor of PDPH in Spinal Anesthesia for Cesarean Delivery
The Optic Nerve Sheath Diameter (ONSD), measured non-invasively by bedside ultrasound, is a well-established surrogate for intracranial pressure (ICP), as the optic nerve sheath is continuous with the intracranial dura mater and…
- Trial name
- NCT07360756
- Testing
- Study Cohort (Single Cohort)
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Al-Azhar University
Caesarean Delivery, Hypotension Postprocedural
Comparison of Classic and Sequential Spinal Techniques for Preventing Hypotension During Cesarean Delivery.
Given the clinical importance of maternal hypotension, the potential advantages of sequential spinal dosing warrant formal evaluation in a prospective, adequately powered randomized controlled trial.
- Trial name
- NCT07327866
- Testing
- Classic group, Sequential group
- Where
- Egypt
- Volunteers
- 94 people
- Sponsor
- Al-Azhar University
Transcutaneous Electric Nerve Stimulation, Analgesia
Transcutaneous Electrical Nerve Stimulation for Post-Cesarean Pain Control
Purpose of study is to evaluate the efficacy of transcutaneous electrical nerve stimulation (TENS) for post-operative pain control after a cesarean delivery compared to placebo and no TENS.
- Conditions
- Transcutaneous Electric Nerve Stimulation, Analgesia, Cesarean Section
- Trial name
- NCT04399707
- Testing
- Transcutaneous electrical nerve stimulation (TENS) unit
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Hawaii Pacific Health
Postpartum Hemorrhage, Delivery Complication
Trends in the Administration of Tranexamic Acid for Postpartum Hemorrhage
Postpartum hemorrhage (PPH) is the global leading cause of maternal death, with 20-30% of maternal deaths in Thailand linked to hemorrhage.
- Conditions
- Postpartum Hemorrhage, Delivery Complication, Cesarean Section Complications, Perinatal Problems
- Trial name
- NCT07278037
- Testing
- Tranexamic acid
- Where
- Thailand
- Volunteers
- 648 people
- Sponsor
- Mahidol University
Spinal Induced Hypotension in Cesarean Delivery
Minimum Effective Volume of Crystalloid Co-Loading to Prevent Spinal Anesthesia-Induced Hypotension in Cesarean Section
The goal of this clinical trial is to find the minimum effective volume of IV crystalloid that should be given with phenylephrine to prevent hypotension caused by spinal anesthesia in healthy, term pregnant adults having elective…
- Trial name
- NCT07324512
- Testing
- Intravenous Crystalloid Co-Loading
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Postpartum Hemorrhage (Primary)
Effect of Co-administration of Carbetocin and Calcium Chloride on Uterine Tone in Patients Undergoing Elective Cesarean Delivery
Postpartum hemorrhage (PPH) is a leading cause of maternal mortality, and its severity has been increasing globally, including in high-income countries.
- Trial name
- NCT07187544
- Testing
- Calcium Chloride, Carbetocin
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pain, Postoperative Pain
Comparison of Transversalis Fascia Plane Block and Erector Spinae Plane Blocks in Cesarean Section
Cesarean section is one of the most common major surgical procedures performed worldwide,, Post-cesarean analgesia should provide adequate pain control while allowing the mother to remain active to meet the needs of the baby.
- Trial name
- NCT05117307
- Testing
- Bupivacaine 0.25% Injectable Solution
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Erzurum Regional Training & Research Hospital
Hypotension After Spinal Anesthesia, Hypotension During Cesarean Delivery
Comparison of the Efficacy of Continuous Metaraminol Infusion Versus Continuous Norepinephrine Infusion for the Prevention of Hypotension During Cesarean Section Under Spinal Anaesthesia. A Randomised Controlled Trial.
The aim of this double-blind randomised study will be to compare a fixed-rate prophylactic metaraminol infusion to a fixed-rate prophylactic norepinephrine infusion during elective cesarean section under combined spinal-epidural…
- Trial name
- NCT07363109
- Testing
- Metaraminol infusion, Norepinephrine infusion
- Volunteers
- 80 people
- Sponsor
- Aretaieion University Hospital
Misoprostol, Respiratory Distress Syndrome (RDS) of Neonate
Misoprostol Before Caesarean Section
The aim of our study is to evaluate the efficacy of Misoprostol before elective cesarean section in pregnant women with gestational age less than 38 weeks for preventing the occurrence of neonatal respiratory morbidity.
- Conditions
- Misoprostol, Respiratory Distress Syndrome (RDS) of Neonate, Caesarean Section
- Trial name
- Miso/CS (NCT06946914)
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Caesarean Section
The Impact of Virtual Reality Glasses on Maternal Satisfaction and Postpartum Comfort in Cesarean Sections Performed Under Spinal Anesthesia
Due to the stressful nature of cesarean birth, it is important that the use of virtual reality (VR) glasses is both feasible and effective.
- Trial name
- NCT07247643
- Testing
- (Intervention Group): Virtual Reality Glasses, Control Group
- Volunteers
- 96 people
- Sponsor
- Büşra Küçüktürkmen
Hypothermia, Shivering
Effect Of Acupressure On Hypothermıa And Shıverıng After Cesarean Sectıon
This research was planned to determine the effect of acupressure on hypothermia and shivering after cesarean section. H01: There is no difference in hypothermia findings between women who received acupressure and women in the…
- Conditions
- Hypothermia, Shivering, Postoperative Hypothermia, Postoperative Shivering
- Trial name
- NCT07864376
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Cesarean Delivery Affecting Fetus or Newborn, Labor (Obstetrics)--Complications
Two Previous Cesarean and Vaginal Birth Before and After Starting Training and Protocols
In 2015 ObGyn Dept of Santo Spirito Hospital in Pescara (Italy) started protocol for previous CS vaginal birth. In 2021 was started a protocol for training on obstetric emergencies and protocol on two previous cesarean was…
- Conditions
- Cesarean Delivery Affecting Fetus or Newborn, Labor (Obstetrics)--Complications, Hemorrhagic Complications
- Trial name
- TOLA2C Train (NCT07258459)
- Testing
- Acceptance, rate of vaginal birth and safety
- Where
- 2 sites in Italy
- Volunteers
- 2,016 people
- Sponsor
- G. d'Annunzio University
Pregnant Women, Cesarean Section
Evaluation of the Absence of Intraoperative Bladder Catheterization in Case of Planned Cesarean Section
The hypothesis of this trial is that the absence of systematic bladder catheterization in patients performing spontaneous urination in the hour preceding the planned cesarean section under spinal anesthesia would not lead to more…
- Trial name
- C2S (NCT06357546)
- Testing
- Spontaneous urination during the hour before caesarean section., Systematic bladder catherization during caesarean section.
- Where
- 2 sites in France
- Volunteers
- 550 people
- Sponsor
- University Hospital, Montpellier
Pregnancy, Cesarean Section
Effects of High Flow Humidified Oxygen on Umbilical Artery Acid-base Balance in Cesarean Section Under Spinal Anesthesia
Spinal anesthesia is the most commonly used anesthetic technique for cesarean section in developed countries, but vasodilation and a decrease in systemic vascular resistance caused by sympathetic blockade result in hypotension in…
- Conditions
- Pregnancy, Cesarean Section, Spinal Anesthesia
- Trial name
- NCT07515716
- Testing
- high-flow nasal oxygen, conventional nasal cannula oxygen
- Volunteers
- 200 people
- Sponsor
- Yonsei University
Shared Decision Making, Cesarean Section
Shared Decision-Making During Anesthesia Consent for Elective Cesarean Delivery
Shared decision-making (SDM) is the accepted ethical and legal standard for informed consent, but it is not known how it operates in anesthesia consent for cesarean delivery.
- Conditions
- Shared Decision Making, Cesarean Section, Anesthesia, Obstetrical, Informed Consent
- Trial name
- SDM-Consent (NCT07858084)
- Testing
- Observation of anesthesia consent encounter and postpartum questionnaire
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- University of British Columbia
Post Traumatic Stress Disorder, Post Partum Depression
Predictive Value of Early Peritraumatic Distress Screening for Childbirth-PTSD Following Unplanned Cesarean Delivery
The goal of this observational study is to learn whether early postpartum screening tools can predict the development of childbirth-related post-traumatic stress symptoms in individuals who undergo unplanned cesarean delivery.
- Conditions
- Post Traumatic Stress Disorder, Post Partum Depression, Acute Stress Symptoms
- Trial name
- PREDICT (NCT07561632)
- Testing
- Postpartum Psychological Screening
- Where
- Canada
- Volunteers
- 420 people
- Sponsor
- University of British Columbia
Anxiety, TOLAC
Educational Video, Anxiety, and Mode of Delivery After Previous Cesarean
This interventional study evaluates whether video-based patient education regarding Trial of Labor After Cesarean (TOLAC) reduces maternal anxiety compared with standard verbal counseling.
- Conditions
- Anxiety, TOLAC, Previous Cesarean Delivery, Trial of Labor After Cesarean
- Trial name
- NCT07338747
- Testing
- Video-Based Educational Intervention, Standard Verbal Counseling
- Volunteers
- 90 people
- Sponsor
- Wolfson Medical Center
Placenta Accreta Spectrum, Placenta Previa
Hematological and Coagulation Markers in Predicting Placenta Accreta Spectrum in Placenta Previa
Placenta accreta spectrum (PAS) is a serious pregnancy complication where the placenta attaches too deeply into the wall of the uterus.
- Trial name
- NCT07826247
- Volunteers
- 130 people
- Sponsor
- Assiut University