Clinical trials: CUP
Cancer, CUP
Living Without Answers - ILLUMINATE CUP
This project aims to improve care, service delivery, and patient experience for people with Cancer of Unknown Primary (CUP) by addressing a critical gap in understanding the lived experiences of patients and carers.
- Conditions
- Cancer, CUP, Cancer Unknown Primary
- Trial name
- ILLUMINATE CUP (NCT07712965)
- Volunteers
- 20 people
- Sponsor
- The Clatterbridge Cancer Centre NHS Foundation Trust
no Obvious Abnormalities, Diabetic Retinopathy (DR)
Retinal Clinical Assessment With AI-derived Quantitative Information
This randomized controlled trial evaluates whether providing clinicians with AI-derived quantitative retinal information improves the quality and efficiency of retinal clinical assessment.
- Conditions
- no Obvious Abnormalities, Diabetic Retinopathy (DR), AMD, Cup-to-disc Ratio Bigger Than 0.5
- Trial name
- NCT07291960
- Testing
- AI-derived retinal quantitative information-assisted reporting
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Sexual Transmitted Disease, Vaginosis, Bacterial
Impact of Internal Menstrual Protections on Immunity and Vaginal Microbiota
The availability, effectiveness, and safety of menstrual protection represent a key public health issue. However, research on women's menstrual and sexual health remains extremely limited.
- Conditions
- Sexual Transmitted Disease, Vaginosis, Bacterial, Mycosis, Urogenital Disease
- Trial name
- CUPS2 (NCT07199998)
- Testing
- Samples collection (whole blood, urine, vaginal and cervical cells)
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centre National de la Recherche Scientifique, France
IUD; Complications, Mechanical, Menstrual Cup
Pilot Study of Suction as a Mechanism of IUD Expulsion With Concomitant Menstrual Cup Use
This study will provide pilot data examining suction as a mechanism of IUD displacement with menstrual cup use. The investigator hypothesize that manufacturer-recommended menstrual cup insertion and removal by breaking the seal…
- Trial name
- NCT05254041
- Testing
- Menstrual Cup Removal
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Malignant Tumor With Metastasis, CUP
Evaluating the Predictive Capability of Transcriptomic Profiling for Identifying the Primary Site of Metastatic Tumors
This study will enroll patients with metastatic malignancies. Tumor samples (fresh or formalin-fixed paraffin-embedded tissue specimens) will undergo RNA extraction and next-generation sequencing (RNA-seq).
- Trial name
- NCT07319949
- Volunteers
- 30 people
- Sponsor
- Fudan University
Menstrual Cup, Menstrual Hygiene Management
The Use of Menstrual Cups in the Menstrual Health and Hygiene Management of Women Who Use Wheelchairs
This study is designed to evaluate the impact of menstrual cup use on menstrual health and hygiene management among women who use wheelchairs.In addition, the study will serve as a reference for future research that includes…
- Conditions
- Menstrual Cup, Menstrual Hygiene Management, Disabled People
- Trial name
- NCT07137663
- Testing
- Educational and practical intervention on menstrual cup use
- Volunteers
- 30 people
- Sponsor
- Hülya ULAŞLI KABAN
Menstrual Cup
The Effect of Menstrual Cup Use on Menstrual Life and Sleep Quality
Women's reproductive age is an important process that begins with menarche and ends with menopause. During this period, women need to use safe, effective and affordable products during their menstrual periods.
- Trial name
- NCT06718790
- Testing
- Using menstrual cup, Using menstrual pads
- Where
- Turkey (Türkiye)
- Volunteers
- 125 people
- Sponsor
- Trakya University
Optic Nerve Cup, Intracranial Pressure Increase
Effect of Lithotomy Position on Optic Nerve Sheath Diameter
In this study, the effect of increased venous return and increased intra-abdominal pressure on intracranial pressure in the lithotomy position was evaluated.
- Trial name
- NCT06464419
- Testing
- ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
NSCLC Stage IV, CRC
Donation of Post Mortem Tumor Tissues
DONUM is an observational prospective independent protocol for patients with advanced lung cancer, colorectal cancer or cancer of unknown primary, willing to donate their tumor tissue samples post mortem for biomedical research…
- Conditions
- NSCLC Stage IV, CRC, CUP
- Trial name
- DONUM (NCT03385980)
- Testing
- Proteomic analysis
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Niguarda Hospital
Menstrual Cup, Intrauterine Device Migration
Shifting of Intrauterine Device and Use of the Menstrual Cup: Case-control Study
In France, 26% of women of childbearing age use an intrauterine device (IUD) containing copper or levonorgestrel as a method of contraception. Failures of IUD contraception are mainly due to shifting or expulsion of the IUD.
- Trial name
- CUP-DIU (NCT04782583)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 740 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Femoral Head Size, Cup Size THP
Correlation Between Femoral Head and Cup Size and Postoperative Pain in Total Hip Arthroplasty
We want to investigate the correlation between the native femoral head and the implanted cup in Total hip arthroplasty. As second parameter to investigate we believe an oversized cup will cause groin pain.
- Conditions
- Femoral Head Size, Cup Size THP, Postoperatie Groin Pain
- Trial name
- jantje (NCT04637958)
- Testing
- THA
- Where
- Belgium
- Volunteers
- 463 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Total Hip Arthroplasty, Acetabular Cup
A Prospective RSA and Clinical Evaluation of the Trident II Acetabular Cup
The objective of this study is to use radiostereometric analysis (RSA) and clinical outcome measures to evaluate early post-operative implant stability and the clinical performance of Stryker's Trident II Acetabular Cup.
- Trial name
- NCT03261986
- Testing
- Radiostereometric Analysis, total hip arthroplasty with RSA bead implantation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Midwest Orthopaedics at Rush
Peritoneum Cancer, Peritoneum Neoplasm
International Registry of Patients Treated With Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC)
Multicentric, international, web-based prospective documentation of the indications and results of Pressurized Aerosol Chemotherapy (so-called PIPAC or PITAC) for treating malignant pleural and peritoneal diseases.
- Conditions
- Peritoneum Cancer, Peritoneum Neoplasm, Pleural Cancer, Pleural Effusion
- Trial name
- PIPACRegis (NCT03210298)
- Testing
- PIPAC
- Where
- 16 sites in Argentina, Australia and 11 more
- Volunteers
- 1,000 people
- Sponsor
- Sabine Rhode
Neoplasms, Unknown Primary, CUP
Outcomes of FoundationOne Directed Therapy in Cancer of Unknown Primary
The goal of the current study is to determine whether Foundation Medicine's next generation sequencing assay, called FoundationOne, will provide information that allows physicians to make treatment decisions using targeted…
- Conditions
- Neoplasms, Unknown Primary, CUP, Metastatic Disease, Poorly Differentiated Adenocarcinoma
- Trial name
- NCT02628379
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Foundation Medicine
Radiostereometric Analysis, Vitamin E Liner
A Prospective Radiostereometric Analysis and Clinical Evaluation of the Zimmer® Continuum® Acetabular Cup With Vitamin E Stabilized Polyethylene
The purpose of this study is to use Radiostereometric Analysis (RSA) and clinical outcome measures to evaluate early, post-operative implant stability, post-operative implant fixation, clinical performance, and in-vivo wear of…
- Conditions
- Radiostereometric Analysis, Vitamin E Liner, Zimmer® Continuum® Acetabular Cup
- Trial name
- NCT01754155
- Testing
- RSA images
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Central DuPage Hospital