Clinical trials: CT Angiography
Chest Pain, Acute Coronary Syndrome
High-Sensitivity Troponin T and Coronary Computed Tomography Angiography for Rapid Diagnosis of Emergency Chest Pain
The purpose of this study is to determine the efficacy and safety of an evaluation strategy based on utilization of high sensitivity cardiac troponin T (hscTnT), followed by coronary computed tomography angiography (CCTA) in…
- Trial name
- TRUE (NCT01836211)
- Testing
- Fast strategy, Standard of care strategy
- Where
- Spain
- Volunteers
- 101 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Acute Coronary Syndrome, Coronary Bypass Stenosis
Coronary CT Angio Evaluating Graft Patency in ACS Patients Treated With DAPT or Single ASA After CABG (CoCAP)
The purpose of this study is to compare the presence of graft patency in single aspirin vs dual anti platelet therapy (DAPT) treatment including ticagrelor in patients with acute coronary syndrome (ACS) treated with coronary…
- Trial name
- NCT04783701
- Where
- 6 sites in Norway, Sweden
- Volunteers
- 360 people
- Sponsor
- University Hospital, Linkoeping
Atrial Fibrillation
Coronary Computed Tomography AngioGraphy Prior to Catheter Ablation in Patients With Atrial FIBrillation
The purpose of this randomized, controlled trial is to investigate whether coronary computed tomography (CT) angiography prior to catheter ablation and derived treatment (medical anti-ischemic and multimodality treatment and/or…
- Trial name
- FIBCAG (NCT05978388)
- Testing
- Analysis of coronary CT Angiography and CAC scoring at the time of catheter ablation
- Where
- Denmark
- Volunteers
- 852 people
- Sponsor
- Tor Biering-Sørensen
Coronary Angiography, Fractional Flow Reserve, Myocardial
Fractional Flow Reserve Derived From CT Related Treatment
This study is a retrospective, single-center study.This experiment aims to explore the influence of CT-FFR as a relevant for revascularization on the prognosis of patients with coronary heart disease, assessing concurrent on…
- Conditions
- Coronary Angiography, Fractional Flow Reserve, Myocardial, Coronary Artery Disease
- Trial name
- NCT05319119
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Pulmonary Embolism
Evaluation of the PERC Score and the YEARS Algorithm in the Diagnosis of Pulmonary Embolism in the Emergency Department
The current diagnostic strategy for pulmonary embolism relies on clinical evaluation, followed by D-dimer testing and chest CT angiography. However, this approach leads to overuse of CT angiography.
- Trial name
- EP (NCT07313501)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Strasbourg, France
Metabolic Syndrome
Effect of Aged Garlic Extract on Atherosclerosis
The investigators will be assessing the effect of Aged Garlic Extract on the coronary arteries. The investigators will enroll patients in a double blind study, where half the patients will receive placebo, and have the patients…
- Trial name
- Garlic4 (NCT01534910)
- Testing
- aged garlic extract
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Coronary Stenosis, Hemodynamics
Diagnostic Accuracy of CCTA-derived Versus AngiogRaphy-dErived QuantitativE Flow Ratio (CAREER) Study
To perform CT-QFR, invasive coronary angiography, FFR, and QFR tests on patients with moderate coronary stenosis after coronary CTA examination.
- Conditions
- Coronary Stenosis, Hemodynamics, Coronary Artery Disease, Coronary Computed Tomography Angiography
- Trial name
- CAREER (NCT04665817)
- Testing
- CT-QFR, QFR, FFR
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Fudan University
Pulmonary Embolism (Diagnosis), Pulmonary Embolism Acute
Role of n On-contrast Chest CT (NCCT) Based CT V: Q in Patients With Acute Pulmonary Embolism (aPE)
We are doing the research to see if a CT scan without the dye can help find pulmonary emboli. If you agree to join the study, you will be asked to sign this consent form before we do any research procedures.
- Trial name
- NCT07527117
- Testing
- Additional CT acquisition at low dose (1- 2 mSv)
- Where
- 2 sites in United States
- Volunteers
- 750 people
- Sponsor
- Massachusetts General Hospital
Coronary Artery Disease
Risk Evaluation by COronary CTA and Artificial intelliGence Based fuNctIonal analyZing tEchniques - I
This study is a multicenter, retrospective imaging study. The study intends to retrospectively enroll patients with acute myocardial infarction who had received coronary CTA in a certain time-window before this event.
- Trial name
- RECOGNIZE-I (NCT05884008)
- Where
- 9 sites in China
- Volunteers
- 300 people
- Sponsor
- Ruijin Hospital
Coronary Computed Tomography Angiography, Stable Chest Pain
CCTA Improves Clinical Management of Stable Chest Pain
The investigator aims to prospectively enroll patients who were referred for coronary computed tomography angiography (CCTA) for the assessment of stable chest pain (SCP) suspected of obstructive coronary artery disease (CAD).
- Conditions
- Coronary Computed Tomography Angiography, Stable Chest Pain, Optimal Medical Therapy, Invasive Coronary Angiography
- Trial name
- CICM-SCP (NCT04691037)
- Testing
- CCTA
- Where
- 4 sites in China
- Volunteers
- 50,000 people
- Sponsor
- Tianjin Chest Hospital
Coronary Artery Disease
Quantification of Myocardial Blood Flow Using Dynamic PET/CTA Fused Imagery
This observational prospective clinical study is to develop software tools to fuse coronary anatomy data obtained from CT coronary angiography with dynamic PET data to noninvasively measure absolute myocardial blood flow, flow…
- Trial name
- NCT04221594
- Testing
- Invasive Cardiac Catheterization (ICA), Coronary Computed Tomographic Angiogram (CCTA), Dynamic Cardiac Positron Emission Tomography (dPET)
- Where
- 6 sites in United States, South Korea
- Volunteers
- 68 people
- Sponsor
- Emory University
Coronary Heart Disease, Metabolic Syndrome
Slowing HEART diSease With Lifestyle and Omega-3 Fatty Acids
The purpose of the study is to target inflammation to reduce progression of noncalcified plaque in the coronary arteries using omega-3 fatty acid supplementation compared to standard of care.
- Trial name
- HEARTS (NCT01624727)
- Testing
- Omega 3 acid ethyl esters
- Where
- 2 sites in United States
- Volunteers
- 338 people
- Sponsor
- Beth Israel Deaconess Medical Center
Coronary Artery Disease
Comparison of Image Quality of Coronary Computed Tomography Angiography bEtweeN High concenTRATion and Low concEntration Contrast Agents(CONCENTRATE Trial)
According to CT technology development, cardiac CT is very useful examination as noninvasive examination and the accuracy in locating lesions has increased to 95%.
- Trial name
- NCT02549794
- Testing
- CT angiography with high concentration contrast agent, CT angiography with low concentration contrast agent (320), CT angiography with low concentration contrast agent (270)
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Yonsei University
Complex Aortic Surgery
Coronary CT Angiography in Aneurysms Repaired With Open or Endovascular Approach
This proposal is for the pilot study that will inform the conduct of a larger prospective randomized controlled trial to guide perioperative work up and the cost/utility of CTCA (high definition CT coronary angiography.)
- Trial name
- CARE (NCT01211548)
- Testing
- contrast CTA of the CAP
- Volunteers
- 40 people
- Sponsor
- The Cleveland Clinic
Chest Pain, Coronary Artery Disease
Study of Value of Cardiac PET Scans With or Without CT Angiography and/or Measurement of Coronary Flow Reserve
How does PET myocardial perfusion imaging involving CT angiography and measurement of coronary flow reserve affect patient care.
- Trial name
- NCT00669968
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Kettering Health Network
Coronary, Coronary Artery Disease
CAPRA-EVO: a Randomized Serial PCCT Trial of Early Evolocumab After ACS
The CAPRA-EVO trial is a single-center, randomized, open-label study with blinded endpoint assessment comparing early evolocumab plus standard lipid-lowering therapy versus standard-of-care lipid-lowering therapy in patients with…
- Trial name
- CAPRA-EVO (NCT07612774)
- Testing
- Evolocumab, Serial photon-counting coronary computed tomography angiography, Standard Lipid-Lowering Therapy
- Where
- 2 sites in China
- Volunteers
- 232 people
- Sponsor
- West China Hospital
Contrast Enhanced X-ray Based Examination
A Study, Called UV Population, to Learn More About the Safety of the Study Drug Ultravist, Which is Given to Get Clearer X-ray Pictures, in People of Different Sexes, Races, and From Different Countries/Regions
This is an observational study in which patient data from the past of people who received Ultravist prior to an X-ray based scan are studied.
- Trial name
- NCT05428397
- Testing
- Iopromide (Ultravist, BAY86-4877)
- Where
- Germany
- Volunteers
- 152,233 people
- Sponsor
- Bayer
Aortic Disorders, Carotid Disease
A Multicenter Study of Iomeron®-400 Used With Multi-detector Computed Tomography Angiography (MDCTA)
This is a Phase IV multicenter, open-label study and is being implemented in order to assess diagnostic image quality of MDCTA in subjects undergoing computed tomography angiography (CTA) of the thoraco-abdominal aorta, and the…
- Conditions
- Aortic Disorders, Carotid Disease, Pulmonary Disease, Peripheral Artery Disease
- Trial name
- Iomeron®-400 (NCT02596048)
- Testing
- Iomeron
- Where
- 5 sites in China
- Volunteers
- 224 people
- Sponsor
- Bracco Diagnostics, Inc
Breast Cancer
CT-Angiography Prior to DIEP Flap Breast Reconstruction
This study will Investigate whether or not preoperative computed tomography (CT) angiography will lower operative times and post operative complications for breast reconstruction performed with a deep inferior epigastric artery…
- Trial name
- NCT02883387
- Testing
- Preoperative CT angiography, No Preoperative Imaging
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Colorado, Denver
Coronary Artery Disease of Significant Bypass Graft, Coronary Syndrome
Implementation of Contemporary Coronary CT Angiography in Clinical Practice
Coronary CT angiography (CCTA) has been recognized as the first-line diagnostic test for most patients with suspected coronary syndrome, often acting as a gatekeeper for invasive coronary angiography.
- Conditions
- Coronary Artery Disease of Significant Bypass Graft, Coronary Syndrome, Coronary Arteriosclerosis
- Trial name
- CONCORDE (NCT06273033)
- Where
- Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Humanitas Hospital, Italy