Clinical trials: CPAP
Hypertension, Cardiac Function and Hemodynamics
AKTIIA OBPM to Assess CPAP Effect on Blood Pressure in Obstructive Sleep Apnea
The goal of this clinical trial is to learn if positive airway pressure (CPAP) therapy works for blood pressure (BP) control in obstructive sleep apnea (OSA) adult patients plus undiagnosed hypertension (HBP), using a cuffless…
- Conditions
- Hypertension, Cardiac Function and Hemodynamics, Usability, Patient Experience
- Trial name
- AVLA1 (NCT06446934)
- Testing
- CPAP
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Hospital Universitario Araba
Obstructive Sleep Apnea (OSA), Suspected Obstructive Sleep Apnea
Empirical CPAP Therapy for Suspected Obstructive Sleep Apnea in a Resource-Limited Setting
Obstructive sleep apnea (OSA) is a condition where a person's airway repeatedly collapses during sleep, causing them to stop breathing briefly and disrupting their rest.
- Conditions
- Obstructive Sleep Apnea (OSA), Suspected Obstructive Sleep Apnea, Sleep Apnea Syndromes
- Trial name
- NCT07693101
- Volunteers
- 80 people
- Sponsor
- Assiut University
Obstructive Sleep Apnea, CPAP Treatment
OurSleepKit To Support CPAP Adherence
The goal of this clinical trial is to learn if a couple-focused mobile health intervention will improve the use of continuous positive airway pressure (CPAP), the primary treatment option for obstructive sleep apnea (OSA).
- Conditions
- Obstructive Sleep Apnea, CPAP Treatment, Treatment Adherence
- Trial name
- NCT06621511
- Testing
- OurSleepKit
- Where
- 2 sites in United States
- Volunteers
- 360 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Hypertension, Sleep Apnea
Losartan in Hypertensive Men and Women With Sleep Apnea Before and on Continuous Positive Airway Pressure (CPAP) Treatment
Obstructive sleep apnea (OSA) is a highly prevalent condition in hypertensive patients. The renin-angiotension-aldosterone-system (RAAS) has a central role in blood pressure control.
- Trial name
- LosartanPAP (NCT00701428)
- Testing
- Losartan, CPAP
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Skaraborg Hospital
Obstructive Sleep Apnea Syndrome
Feasibility Evaluation of CPAP in the Treatment of Obstructive Sleep Apnea Synchrone in the Acute Phase of Stroke
This project is focused on the treatment of obstructive sleep apnea in the acute phase of stroke. Stroke is a frequent pathology with a high morbidity and mortality rate.
- Trial name
- NCT02522819
- Testing
- CPAP
- Where
- France
- Volunteers
- 13 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Apnea Syndrome, Apnea, Obstructive
Effect of Hypnosis on Adherence to Continuous Positive Airway Pressure.
The prevalence of sleep-disordered breathing is high, with an apnea-hypopnea index of over 15 per hour found in 49.7% of men and 23.4% of women in the general population (1).
- Trial name
- HypnOSA (NCT06397365)
- Testing
- medical hypnosis
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Solelhac Geoffroy
Sleep Apnea, Obstructive, Endothelial Dysfunction
Impact of the Mandibular Advancement Device on Sleep Apnea During CPAP Withdrawal
Obstructive sleep apnea hypopnea syndrome (OSAS) is a frequent disease with neuropsychological and cardiovascular (CV) consequences.
- Trial name
- ORTAP (NCT05939934)
- Testing
- Mandibular advancement device treatment
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Angers
Prematurity, Respiratory Distress Syndrome
Comparing Different Delivery Systems of Continuous Positive Airway Pressure in Neonates
The goal of this clinical trial is to compare late preterm newborn lung physiology when supported with different continuous positive airway pressure (CPAP) devices.
- Trial name
- NCT06038565
- Testing
- RAM cannula ventilator CPAP, Occlusive interface bubble CPAP
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Obstructive Sleep Apnea
Sleep Schedules Modifications in Sleep Apnea Patients Treated by nCPAP
In Obstructive sleep apnea (OSA) patients, sleep is disrupted and sleep quality is very poor. The investigators can suppose that with continuous positive airway pressure (CPAP) therapy, there is an improvement in sleep quality…
- Trial name
- NCT01355419
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Chronic Obstructive Airway Disease
Cardiac Hemodynamics in Overlap Syndrome (COPD With Obstructive Sleep Apnea)
Patients with both sleep apnea and COPD have overlap syndrome, but their optimal management is not known. We plan to conduct a randomized trial of of bi-level PAP vs.
- Trial name
- NCT01261377
- Testing
- Bi-level positive airway pressure (BPAP), Oxygen, CPAP
- Where
- 2 sites in United States
- Sponsor
- Brigham and Women's Hospital
Obstructive Sleep Apnea Syndrome, Brain Infarction
Consequences of Obstructive Sleep Apnea Syndrome (OSAS) After Ischemic Subtentorial Stroke.
Obstructive Sleep Apnea Syndrome (OSAS) is associated with stroke as a risk factor but little is known about the consequences of OSAS on the outcome and the survival after stroke.
- Trial name
- NCT01561677
- Testing
- Continuous Positive Airway pressure-RESPIRONICS
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Montpellier
Obstructive Sleep Apnea
Self-Management of Continuous Positive Airway Pressure Settings
Obstructive sleep apnea (OSA) is a major chronic condition affecting the quality of life of millions of Americans. Per the Institute of Medicine new treatment adherence strategies are needed to help improve the quality of care…
- Trial name
- ImPRESS (NCT03536572)
- Testing
- Sleep Apnea Self-Management Program
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- VA Office of Research and Development
Sleep Apnea Syndrome (OSAS), Sleep Apnea Syndrome
Personalised Treatment for OSA
Obstructive sleep apnea (OSA) is a sleep disorder characterized by repetitive episodes of partial or complete obstruction of the upper airway during sleep.
- Conditions
- Sleep Apnea Syndrome (OSAS), Sleep Apnea Syndrome, Sleep Apnea Syndrome, Obstructive, Sleep Apnea/Hypopnea Syndrome
- Trial name
- NCT06915077
- Where
- Belgium
- Volunteers
- 850 people
- Sponsor
- University Hospital, Antwerp
Acute Cardiogenic Pulmonary Edema
OUT-OF-HOSPITAL CPAP STUDY
Evaluate efficacy and safety of CPAP in a randomised standard treatment controlled study, in out-of-hospital patients with acute cardiogenic pulmonary edema.
- Trial name
- NCT00439075
- Testing
- CPAP, standard treatment
- Where
- France
- Volunteers
- 124 people
- Sponsor
- University Hospital, Toulouse
Ventilator Lung
Pressure Support Ventilation Versus Continuous Positive Air Way Pressure (CPAP) Using I Gelin Adult Patients,
Introduction of Supra glottic airway devices (SAD) has revolutionized the airway management. The first successful supraglottic airway device, the Laryngeal Mask Airway(LMA).The various other SADs include ProSeal LMA, Intubating…
- Trial name
- NCT05116839
- Testing
- the first 15 minutes with pressure support ventilation, the following 15 minutes ventilation will be changed to continous positive air way pressureCPAP mode, i gel air way
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Mansoura University
Obstructive Sleep Apnea
Treatment Adherence and Outcomes in Three Modalities of Continuous Positive Airway Pressure Treatment for Obstructive Sleep Apnea
The purpose of this study is to compare the treatment adherence and effects in three modalities of Continuous Positive Airway Pressure Treatment for Obstructive Sleep Apnea.
- Trial name
- NCT00873977
- Testing
- CPAP (REMstar (Respironics))
- Where
- Japan
- Volunteers
- 93 people
- Sponsor
- Kyoto University, Graduate School of Medicine
Severe Asthma With Obstructive Sleep Apnea
The Efficacy of Continuous Positive Airway Pressure in Achieving Asthma Control in Patients With Severe Asthma and Obstructive Sleep Apnea
Asthma is a common heterogeneous chronic disorder of the airways, characterized by variables, usually reversible and recurring symptoms related to one or more of airflow obstruction, bronchial hyper-responsiveness, and underlying…
- Trial name
- NCT05470153
- Testing
- Continuous Positive Airway Pressure
- Where
- Saudi Arabia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Neonatal Respiratory Distress Syndrome
Heated, Humidified High-flow Nasal (HHHFN) Cannula vs Nasal Continuous Positive Airway Pressure in Respiratory Distress in Premature Neonates
Newborn babies who have difficulty breathing may need breathing support to help them receive enough oxygen. Two commonly used methods are heated, humidified high-flow nasal cannula (HHFNC), which delivers warmed, moist air and…
- Trial name
- NCT07891494
- Testing
- Heated Humidified High-Flow Nasal Cannula therapy, nCPAP
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Pakistan Air Force (PAF) Hospital Islamabad
Hypertension, Resistant to Conventional Therapy, Sleep Apnea
Physical Activity Program for Reducing Blood Pressure in Sleep Apnea Patients With Resistant Hypertension
Investigators hypothesize that CPAP treatment for suppressing OSAS in combination with a physical activity program will optimize 24-hour blood pressure control in patients with OSA-related resistant hypertension.
- Trial name
- RAP (NCT02057783)
- Testing
- Physical activity
- Where
- 5 sites in Canada, France and 1 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- AGIR à Dom
Obstructive Sleep Apnea Syndrome
Evaluation of a New Medical Device AL539 in Patients With Obstructive Apneas Sleep Syndrome
Continuous Positive Airway Pressure (CPAP) is the standard treatment in patients with Obstructive Sleep Apnea Syndrome (OSAS). The goal of the study is to evaluate CPAP treatment duration recorded by the AL539 during attended…
- Trial name
- AL539 (NCT01441622)
- Testing
- AL539 (SRETT)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Air Liquide Santé International