Clinical trials: CKD Stage 3
Chronic Disease, Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight
Truway Diagnostic Tools in Primary Care
This study evaluates the effectiveness of Truway Health-sourced portable diagnostic devices, including ultrasound and blood glucose monitors, in early detection of chronic conditions in outpatient primary care settings.
- Conditions
- Chronic Disease, Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight, Hypertension, Cardiovascular Disease Acute
- Trial name
- TruDxPC (NCT07209527)
- Testing
- Truway Portable Ultrasound Device, Truway Blood Glucose Monitor, Standard Oral Hypoglycemic Agent
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Truway Health, Inc.
CKD (Chronic Kidney Disease) Stage 5D
Impact of Propionic Acid on Regulatory T Cell Function in Children With CKD
Pro-Kids is a multi-center, double-blind, randomized and placebo-controlled intervention study in children with chronic kidney disease.
- Trial name
- Pro-Kids (NCT05858437)
- Testing
- Sodium propionate
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Charite University, Berlin, Germany
Chronic Heart Failure, CKD Stage 3
Reducing Fluid Overload in Heart Failure Patients Using a Non-invasive, Renal Independent System
The REFORM-HF study aims to test a new technology, AQUAPASS, designed to assist patients experiencing symptoms of fluid overload due to Heart Failure.
- Trial name
- REFORM-HF (NCT06360380)
- Testing
- AquaPass System
- Where
- 10 sites in United States, Israel
- Volunteers
- 40 people
- Sponsor
- AquaPass Medical Ltd.
Type 2 Diabetes, Chronic Kidney Disease (CKD) Stages G2 to G3b
A Study to Learn More About How Well Finerenone Works in Real-world in People With Type 2 Diabetes and Chronic Kidney Disease in Primary Care (IMSS= Instituto Mexicano Del Seguro Social)
The main purpose of this study is to learn how treatment with finerenone affects the urinary albumin-to-creatinine ratio (uACR), a marker of kidney health, over time in adults with type 2 diabetes and chronic kidney disease who…
- Trial name
- FINE-IMSS-MX (NCT07841015)
- Testing
- Finerenone
- Where
- Mexico
- Volunteers
- 800 people
- Sponsor
- Bayer
CKD (Chronic Kidney Disease) Stage 5D
ASPIrin in Reducing Events in Dialysis ( ASPIRED )
People with kidney failure requiring dialysis have a much higher risk of developing cardiovascular (CV) disease compared with the general population.
- Trial name
- NCT04381143
- Testing
- Aspirin 100 mg Oral Tablet
- Where
- 127 sites in China
- Volunteers
- 9,082 people
- Sponsor
- Guangdong Provincial People's Hospital
CKD, Chronic Kidney Disease (Stages 3b-5)
Fostering Self-Empowerment in CKD Patients Through Food Choice Mapping
This project aims to develop mapping of food choices available for chronic kidney disease (CKD) patients when dining out in Singapore.
- Trial name
- NCT07804316
- Testing
- Mobile application empowerment approach
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Singapore Institute of Technology
End Stage Renal Disease (ESRD), Chronic Kidney Disease (CKD)
Clinical Effectiveness and Resource Use in End-Stage Renal Disease Patients: Remote Patient Monitoring Across Dialysis Modalities
This is a multicenter, prospective, observational real-world study designed to evaluate clinical effectiveness, quality of life, and healthcare resource utilization in patients with end-stage renal disease (ESRD) initiating…
- Trial name
- NCT07781124
- Testing
- Remote patient monitoring-automated peritoneal (RPM-APD), Manual peritoneal dialysis (PD) cohort, Maintenance hemodialysis (HD)
- Where
- 20 sites in China
- Volunteers
- 750 people
- Sponsor
- Vantive Health LLC
Chronic Kidney Disease (CKD) Stage 5, Kidney Dysfunction Requiring Dialysis (KDRD)
Incremental Hemodialysis for Veterans in the First Year of Dialysis (IncHVets)
In this pragmatic clinical trial, which will dovetail with Veterans' routine outpatient dialysis clinic visits in six VA medical centers, the investigators will study 252 Veterans with kidney disease who need to start dialysis…
- Conditions
- Chronic Kidney Disease (CKD) Stage 5, Kidney Dysfunction Requiring Dialysis (KDRD), Dialysis Dependency
- Trial name
- INCHVETS (NCT05465044)
- Testing
- Twice-weekly hemodialysis with incremental crossover to thrice-weekly schedule, Thrice-Weekly Hemodialysis
- Where
- 8 sites in United States
- Volunteers
- 252 people
- Sponsor
- VA Office of Research and Development
CKD Stage 3, CKD Stage 4
Pharmacokinetics, Pharmacodynamics, Safety and Tolerability Evaluation of CTAP101 Extended-release Capsules in Pediatric Participants
The goal of this clinical trial is to evaluate safety, tolerability, and how CTAP101 Capsules work to treat Pediatric Participants with Secondary Hyperparathyroidism, Stage 3 or 4 Chronic Kidney Disease and Vitamin D…
- Conditions
- CKD Stage 3, CKD Stage 4, Secondary Hyperparathyroidism, VDI
- Trial name
- NCT07494045
- Testing
- CTAP101
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- OPKO Health, Inc.
Kidney Transplant, Rejection of Renal Transplant
Development and Validation of HistoMX, a Gene-Expression Platform for Molecular Interpretation of Kidney Allograft Biopsies
This retrospective multicentre observational study developed and validated HistoMX, an automated gene-expression-based platform for multidimensional molecular interpretation of kidney allograft biopsies.
- Conditions
- Kidney Transplant, Rejection of Renal Transplant, Antibody Mediated Rejection, BK Virus Nephropathy
- Trial name
- HistoMX (NCT07700563)
- Volunteers
- 2,410 people
- Sponsor
- Paris Translational Research Center for Organ Transplantation
ESRD, CKD Stage 4
Safety and Efficacy of Canagliflozin in Advanced CKD
The study objective is to characterize the pharmacokinetics (PK), pharmacodynamics, and surrogate measures of efficacy for canagliflozin in patients with advanced CKD, including those receiving HD.
- Conditions
- ESRD, CKD Stage 4, CKD Stage 5
- Trial name
- SIP-AKiD (NCT05309785)
- Testing
- Invokana 300 mg and 100 mg tablet
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Telenurse, CKD Stage 3/4
EFFECTS OF TELENURSING IN PREDIALYSIS PATIENTS
This study aims to evaluate the effect of tele-nursing practices on quality of life and clinical outcomes in predialysis patients with chronic kidney disease.
- Trial name
- Telenurse-CKD (NCT07669142)
- Testing
- Structured Telenursing Education, Counseling, and Follow-up Program
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Istanbul University - Cerrahpasa
End-Stage Kidney Disease (ESKD), Chronic Kidney Disease (CKD)
Comparing Hemodiafiltration to Conventional Hemodialysis: Effects on Clinical and Biochemical Parameters
Chronic kidney disease may progress to end-stage renal disease, a stage in which the kidneys will no longer be able to adequately remove extra fluid and waste products from the body.
- Trial name
- NCT07662889
- Testing
- Conventional Hemodialysis, Hemodiafiltration
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Services Institute of Medical Sciences, Pakistan
CKD Stage 5
Potential Therapeutic Role of Effervescent Calcium-Magnesium Citrate in Chronic Kidney Disease Stage V
The Investigators plan to conduct a long-term trial to explore therapeutic implications of effervescent calcium magnesium citrate (EffCaMgCit) in CKD Stage V (end stage renal disease on hemodialysis).
- Trial name
- NCT03565913
- Testing
- EffCaMgCit, CaAcS
- Where
- United States
- Volunteers
- 269 people
- Sponsor
- University of Texas Southwestern Medical Center
Chronic Kidney Disease (CKD), CKD Stage 1-3
Multimedia Health Education on Physical Fitness and Physical Activity for Patients With Chronic Kidney Disease
This clinical trial aims to determine whether a multimedia educational intervention can effectively improve physical fitness and physical activity levels in patients with chronic kidney disease (CKD), while also evaluating its…
- Trial name
- NCT07493642
- Testing
- Multimedia Health Education, Standard Education Group
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Fu Jen Catholic University Hospital
Exercise, Diet Interventions
Multimodal Intervention for Early Chronic Kidney Disease in Young People: Dysbiosis and Inflammation (CKD)
Chronic kidney disease (CKD) is a progressive condition associated with substantial morbidity, mortality, and healthcare costs. Early detection and timely intervention are critical to modify disease trajectory, particularly in…
- Conditions
- Exercise, Diet Interventions, Symbiotic, CKD Stage 1
- Trial name
- CKD (NCT07483697)
- Testing
- symbiotic
- Where
- Mexico
- Volunteers
- 200 people
- Sponsor
- Centenario Hospital Miguel Hidalgo
ESRD, CKD (Chronic Kidney Disease) Stage 5D
Effect of Canagliflozin on Ultrafiltration & Fibrosis in Patients on Peritoneal Dialysis
This is a phase II, proof-of-concept, placebo-controlled, double-blind, cross-over randomized clinical trial, assessing the effect of canagliflozin on peritoneal membrane function in patients on PD.
- Trial name
- CAN-PD (NCT06913647)
- Testing
- Canagliflozin 300 MG
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Chronic Kidney Disease (CKD) Stage 5, Peritoneal Dialysis Access
PD Catheter Survival: Modified Percutaneous vs Moncrief-Popovich
Peritoneal dialysis (PD) catheter placement technique may affect catheter survival, functionality and infection risk. The Moncrief-Popovich (subcutaneous burying or embedding) technique was developed to reduce exit-site/tunnel…
- Trial name
- NCT07465445
- Testing
- Embedded Peritoneal catheter placement, Modified Percutaneous PD catheter placement
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Hospital Civil de Guadalajara
Diabetes Mellitus Type 2 With Proteinuria, Diabetes Mellitus, Type 2
Treatment Optimization for Patients With Type 2 Diabetes Using Empagliflozin and Finerenone in a Remote Clinical Trial
The goal of this clinical trial is to determine the feasibility of remote clinical trial conduct in patients with type 2 diabetes and elevated albuminuria.
- Conditions
- Diabetes Mellitus Type 2 With Proteinuria, Diabetes Mellitus, Type 2, Diabetes Mellitus, Diabetes
- Trial name
- Optimize@Home (NCT06094920)
- Testing
- Empagliflozin 10 MG, Finerenone, Withings BPM Connect
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- University Medical Center Groningen
Kidney Transplantation, CKD (Chronic Kidney Disease) Stage 5D
Tubeless Spontaneous Ventilation Anesthesia in Kidney Transplantation
The aim of this clinical trial is to compare the intraoperative use of neuromuscular blocking agents and other anesthetic drugs between tubeless spontaneous ventilation anesthesia (TSVA) and conventional endotracheal intubation…
- Trial name
- NCT07377123
- Testing
- Tubeless Spontaneous Ventilation Anesthesia, Endotracheal Tube Anesthesia
- Volunteers
- 60 people
- Sponsor
- Jianxing He