Clinical trials: CGA
Lung Cancer, Non-small Cell Lung Cancer
Comprehensive Geriatric Assessment in Elderly Non-Small Cell Lung Cancer Patients
Lung cancer is responsible for one of the highest incidences of cancer-related mortality globally, and non-small cell lung cancer (NSCLC) accounts for the biggest subtype of lung cancer.
- Trial name
- NCT05230888
- Testing
- Questionnaires about symptoms
- Where
- United Kingdom
- Sponsor
- University of Hull
Neuroendocrine Tumors
Investigation of the Effects of Diet on the Measurement of Plasma Chromogranin in NET Patients
Measurement of plasma chromogranin A remains the most commonly used biomarkers for both screening and monitoring of patients with gastro-entero-pancreatic neuroendocrine tumours (GEP-NET), despite several limitations that…
- Trial name
- DIB-NET (NCT03288402)
- Testing
- ongoing fasted state, intake of caffeine containing beverages or 5-item English breakfast
- Where
- United Kingdom
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Surgery and Anesthesia on Elderly, Comprehensive Geriatric Assessment
To Investigate the Influence of Surgery and Anesthesia on Elderly Population by Using the Comprehensive Geriatric Assessment
Aging is a universal and progressive physiological phenomenon clinically characterized by degenerative changes in both the structure and the functional capacity of organs and tissues.
- Conditions
- Surgery and Anesthesia on Elderly, Comprehensive Geriatric Assessment, Aged
- Trial name
- CGA (NCT04042064)
- Where
- Taiwan
- Volunteers
- 2,000 people
- Sponsor
- Chang Gung Memorial Hospital
Colorectal Neoplasms, Frailty
Effect of CGA for Frail Elderly Patients Operated for Colorectal Cancer - The CRC Frailty-study
This multicentre randomized controlled trial aims to investigate whether an individualized comprehensive geriatric assessment (CGA) and care will improve postoperative results in frail elderly patients undergoing surgery for…
- Conditions
- Colorectal Neoplasms, Frailty, CGA
- Trial name
- NCT04358328
- Testing
- Comprehensive geriatric assessment (CGA) and care, Standard care
- Where
- 2 sites in Sweden
- Volunteers
- 340 people
- Sponsor
- Sahlgrenska University Hospital
Elderly Inpatients, Frail
Prevalence and Influencing Factors of Frailty in Elderly Patients With Heart Failure
The goal of this observational study is to investigate the prevalence and associated factors of frailty in hospitalized elderly patients with heart failure.
- Conditions
- Elderly Inpatients, Frail, Heart Failure Hospitalization, CGA
- Trial name
- NCT07510035
- Where
- China
- Volunteers
- 298 people
- Sponsor
- Zhejiang Hospital
Ischemic Heart Disease
Use of GeriKit to Better Phenotype Older Adults With Ischemic Heart Disease
This study seeks to expand the use of the NYU GeriKit mobile application ("app") in a diverse range of settings to better phenotype older patients, which will enhance both research and patient care.
- Trial name
- NCT05788666
- Testing
- GeriKit Mobile Application
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- NYU Langone Health
Periodontitis and Diabetitis
Chromogranin-A-Derived Peptides and Periodontitis in Diabetic Patients
Periodontitis is a chronic disease of the supporting tissue of the teeth, characterized by bleeding and inflamed gingival, resorption of alveolar bone.
- Trial name
- NCT00399620
- Testing
- Gingival crevicular fluid samples (this procedure is added to the subject usual medical follow-up).
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Neoplasm, Plasma Cell, Lymphoma
Impact of Chemotherapeutic Treatments in Patients Aged 75 Years and Over Treated for Lymphoid Hematological Malignancy
The aim of the study is to assess the prevalence of functional decline in elderly patients treated with chemotherapy or immunochemotherapy for lymphoid hematologic malignancies.
- Trial name
- LYMPHOLD (NCT05101759)
- Testing
- Comprehensive Geriatric Assessment
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Toulouse
Pre-Eclampsia, Eclampsia
Catestatin and Hypertension in Pregnancy
Catestatin is a kind of protein involved with cardiovascular disease. Accumulated evidence shows that Catestatin may be a predictor of primary hypertension, but whether it plays the same role in pregnant hypertensive disorders…
- Conditions
- Pre-Eclampsia, Eclampsia, Hypertension, Pregnancy-Induced, Hypertension in Pregnancy
- Trial name
- NCT03200743
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Yuchen Pan
Neuroendocrine Tumors
ProGRP, CgA, NSE and TUM2-PK in in Patients With Neuroendocrine Tumors
The purpose of this study is to determine whether monitoring of levels of Serological Markers ProGRP, CgA, NSE and Pyruvate Kinase M2 are effective in the Evaluation of Diagnosis, Monitoring Therapeutic Effects and Predicting…
- Trial name
- NCT00851604
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Hadassah Medical Organization
Prostate Cancer
Effects of Octreotide Acetate on Circulating Levels of Chromogranin A in Advanced Prostate Cancer Patients
The present study will provide information on whether the somatostatin analog, octreotide acetate, could have an inhibitory effect on circulating chromogranin A.
- Trial name
- NCT00166725
- Testing
- Octreotide LAR
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Novartis
Non Hodgkin Lymphoma (NHL), Diffuse Large B-cell Lymphoma (DLBCL)
Comprehensive Geriatric Assessment to Predict Toxic Events in Older Patients With Non-Hodgkin Lymphoma With Imbedded Pilot Study of Pre-Phase Therapy
This study will evaluate the ability of a largely self-administered geriatric assessment (GA) to predict toxicity in non-Hodgkin Lymphoma (NHL) patients ≥60 years old receiving chemotherapy or chemoimmunotherapy.
- Trial name
- NCT01829958
- Testing
- rituximab, prednisone, Geriatric Assessment
- Where
- 8 sites in United States
- Volunteers
- 201 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
CGA
Preoperative Comprehensive Geriatric Assessment (CGA) and Postoperative Delirium
The purpose of this research is to find out the best way to reduce delirium in frail, older patients undergoing planned surgery. Delirium is a state of confusion and difficulty concentrating that is temporary.
- Trial name
- NCT07059585
- Testing
- CGA, control
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Miami
Carcinoid Tumors, Neuroendocrine Tumors
Effect of Oral 5-HTP Intake on Urinary 5-HIAA Excretion
This is a research study looking at the effect of 5-Hydroxy Tryptophan (5-HTP) on urine excretion of 5-Hydroxyindolacetic acid (5-HIAA).
- Trial name
- NCT00227136
- Testing
- 5-Hydroxy-Tryptamine
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Western Ontario, Canada
Geriatric Disorder
(MIGA) Mini Geriatric Assessment To Replace the Comprehensive Geriatric Assessment
This is a comprehensive Geriatric Assessment (CGA) currently used to evaluate elderly people in order to be able to assess their multiple organ pathology, cognitive, functional and social problems.
- Trial name
- MIGA (NCT01318759)
- Where
- Israel
- Volunteers
- 400 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Colon Cancer, Rectal Cancer
CGA Guided Ultrafractionated RT and First-line Systemic Treatment in Elderly or Frail Patients with MCRC
This is a prospective, multicentre, cohort study. For cohort 1(CGA cohort), experimental cohort, older or Frail patients with metastatic colorectal cancer will receive Ultrafractionated Radiotherapy (RT) and Comprehensive…
- Trial name
- NCT06665087
- Testing
- Ultrafractionated RT and CGA Guided systemic treatment., Ultrafractionated Radiotherapy, PD-1 antibody
- Volunteers
- 110 people
- Sponsor
- Fudan University
Hematologic Malignancies, Solid Tumor
Impact of the Comprehensive Geriatric Assessment on the Quality of Life OF Elderly Patients
Impact of the Comprehensive Geriatric Assessment on the Quality of Life of elderly onco-hematologic patients' candidates for complex antitumoral therapies: clinical and biological correlatives
- Conditions
- Hematologic Malignancies, Solid Tumor, Elderly Patients
- Trial name
- ONCO-AGING (NCT04478916)
- Where
- Italy
- Volunteers
- 144 people
- Sponsor
- Lorenza Scotti
Elderly Cancer Patients, Cognitive Impairment
Validation of the Freund Clock Drawing Test to Screen for Cognitive Dysfunction in Cancer Patients
A Comprehensive Geriatric Assessment (CGA) has become a fundamental aid in the evaluation and treatment planning of older cancer patients.
- Trial name
- PROACTIVE (NCT01749995)
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- General Hospital Groeninge
Psoriasis
Pathogenesis of Periodontal Disease in Individuals With Psoriasis
The aim of this study is to evaluate the levels of Th17 cell-associated cytokines (IL-17, IL-21, IL-23) and the salivary stress biomarkers cortisol, dehydroepiandrosterone, and Chromogranin A in the pathogenesis of periodontal…
- Trial name
- NCT07158125
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
PreTerm Birth
Linear Growth and Neurobehavioural Outcome in PT Neonates (<34 Wks) at 37 and 40 Wks of CGA
This study will evaluate the association of linear growth on neurobehavioural outcome in preterm neonates at 37 and 40 weeks of (CGA) corrected gestational age.
- Trial name
- NCT02970994
- Volunteers
- 70 people
- Sponsor
- Lady Hardinge Medical College