Clinical trials: CCT
Bladder Cancer
Phase II Gemcitabine + Cisplatin +/- Iressa Bladder CCT
The primary objective of the study is to assess the activity of ZD1839 250 mg once daily in addition to the standard chemotherapy in patients with advanced or metastatic transitional cell carcinoma of the urothelium by estimating…
- Trial name
- NCT00246974
- Testing
- Gemcitabine, Cisplatin, Gefitinib
- Where
- 14 sites in Germany
- Volunteers
- 125 people
- Sponsor
- AstraZeneca
Coronary Bypass Graft Occlusion
Diagnostic and Prognostic Value of Cardiac Biomarkers for Early Coronary Bypass Occlusion in Patients Undergoing Coronary Revascularization
This study is to evaluate the correlation between hs-cTn level as cardiac biomarker for ischemia and early graft occlusion as assessed by CCT in patients undergoing coronary bypass surgery.
- Trial name
- NCT04595630
- Testing
- data collection from the hospital records
- Where
- 3 sites in Croatia, Poland and 1 more
- Volunteers
- 480 people
- Sponsor
- University Hospital, Basel, Switzerland
Surgery, Infection
Efficacy of Bifidobacterium Lactis CCT 7858 in Adults Using Antibiotics
To evaluate the effectiveness of the probiotic Bifidobacterium lactis CCT 7858 in preventing and / or improving gastrointestinal symptoms in adults using antibiotics.
- Trial name
- NCT04742322
- Testing
- Bifidobacterium Lactis CCT7858, Maltodextrin
- Where
- Brazil
- Volunteers
- 116 people
- Sponsor
- Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude
Breast Cancer
Cardiotoxicity of Cancer Therapy (CCT)
The objective of this study is to define the clinical significance of mechanistic biomarkers (including Neuregulin-1Beta) and novel echocardiographic measures of cardiac function in predicting the incident risk of cancer therapy…
- Trial name
- NCT01173341
- Testing
- Echocardiography, Blood Collection, Symptoms Questionnaire
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Chaperonin-Containing TCP-1, Circulating Tumor Cells
Liquid Biopsy Collection Study
The purpose of this study is to develop a liquid biopsy approach for detection of circulating tumor cells (CTC) that could be used in place of the more invasive and potentially risky methods of tissue biopsy.
- Conditions
- Chaperonin-Containing TCP-1, Circulating Tumor Cells, CCT, CTC
- Trial name
- NCT06068348
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Rare Fetal Genetic Diseases, Congenital Malformation
Characterization and Contribution of Genome-wide DNA Methylation (DNA Methylation Episignatures) in Rare Diseases With Prenatal Onset
It is necessary to define reference DNA Methylation Episignatures from fetal DNA. The hypotheses are: It is possible to define reference DNA Methylation Episignatures from fetal DNA extracted from amniotic fluid or frozen tissues…
- Trial name
- FOETEPISIGN (NCT06475651)
- Testing
- Methylation analysis
- Where
- France
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Alcohol Use Disorder
Compensatory Cognitive Training Via Telehealth for Veterans With Alcohol Use Disorders
Most individuals entering treatment for alcohol use disorders (AUDs) present with cognitive deficits across a range of cognitive domains, and these deficits frequently persist for six months or longer following remission.
- Trial name
- CCT-A (NCT06134128)
- Testing
- Motivationally Enhanced Compensatory Cognitive Training for Addictions Group
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Portland VA Medical Center
Nasopharyngeal Carcinoma, De-escalation Therapy
Reduced-dose RT With/Without CCT Versus Standard CCRT for High-risk LANPC Who Achieved CR Post Induction Chemotherapy
This prospective trial aims to enroll patients with high-risk stage III-IVA (AJCC 8th, except T3N0) locoregionally-advanced nasopharyngeal carcinoma (LANPC).
- Trial name
- NCT06092957
- Testing
- Cisplatin-based induction chemotherapy, Full course of PD-1/PD-L1 blockades, Reduced-dose IMRT
- Where
- China
- Volunteers
- 504 people
- Sponsor
- Sun Yat-sen University
Renal Cell Carcinoma
Safety and Efficacy of CCT301 CAR-T in Adult Subjects With Recurrent or Refractory Stage IV Renal Cell Carcinoma
This is a two arm, open-label, dose escalation and dose expansion clinical study to evaluate the safety and efficacy of infusion of autologous CCT301-38 or CCT 301-59 T cells in adult subjects with relapsed and refractory stage…
- Trial name
- NCT03393936
- Testing
- CCT301-38, CCT301-59
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Shanghai PerHum Therapeutics Co., Ltd.
Mild Cognitive Impairment
Effects of tACS Combined With CCT for Patients With MCI
This goal of this study is to explore the effects of transcranial alternating current stimulation(tACS) combined with computerized cognitive training(CCT) on improving cognition for patients with mild cognitive impairment(MCI).
- Trial name
- NCT04135742
- Testing
- Transcranial Alternating Current Stimulation, Cognitive Training
- Where
- 2 sites in China
- Volunteers
- 195 people
- Sponsor
- Shanghai Mental Health Center
Coronary Arterial Disease (CAD)
Health Improvements by Understanding the Determinants of Residual Risk in Coronary Artery Disease and New Targets for Prevention and Treatment
Current medical treatments, in patients with stable coronary artery disease (CAD), mainly target established risk factors and are able to reduce morbidity and mortality but still leave a substantial residual risk of coronary…
- Trial name
- HURRICANE (NCT06601153)
- Testing
- Cardiac CT
- Where
- 2 sites in Italy
- Volunteers
- 961 people
- Sponsor
- Fondazione Toscana Gabriele Monasterio
Alcohol Addiction
Transcranial Magnetic Stimulation in the Treatment of Addiction
The investigators hypothesize that repetitive transcranial magnetic stimulation (rTMS) on the right side of the head will make craving towards alcohol less severe in recently detoxified alcohol addicted patients.
- Trial name
- MAGENTA (NCT01973127)
- Testing
- Verum rTMS
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- IrisZorg
Traumatic Brain Injury, Cognitive Impairment
"Cognitive Rehabilitation With Direct Current Transcranial Stimulation in Post-Traumatic Brain Injury Patients"
The goal of this clinical trial is to investigate the impact of daily self-administered transcranial direct current stimulation (tDCS) therapy on the cognitive function of individuals with moderate to severe cognitive impairment…
- Trial name
- tDCS-TEC (NCT06228872)
- Testing
- Cognitive Computerized Training (CCT) plus Anodic transcranial Direct Current Stimulation (tDCS)
- Where
- Chile
- Volunteers
- 38 people
- Sponsor
- Mutual de Seguridad Hospital Clinico
Psychological Distress
Compassion Cultivation Training (CCT): An Intervention for Caregivers
This study will begin a novel line of research on CCT in Denmark as a preventive intervention for caregivers of people suffering from a mental illness.
- Trial name
- NCT03730155
- Testing
- CCT intervention.
- Where
- 2 sites in Denmark
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Anemia
Effectiveness and Acceptability of Weekly Iron Folic Acid Supplementation With Conditional Cash Transfer (WIFASCCT) Among Adolescent Girls in Four Districts of Pakistan in Low Income Setting
In Pakistan, adolescent girls aged 15-19 years are particularly vulnerable to anemia and malnutrition, with over half (54.7%) being anemic.
- Trial name
- NCT06733844
- Testing
- Weekly iron folic acid supplementations
- Where
- Pakistan
- Volunteers
- 2,131 people
- Sponsor
- Aga Khan University
Diabetes, Older Diabetic Persons Without Dementia
CCT for Older Diabetic Adults
The current study examines the efficiency of a home-based computerized cognitive training (CT) intervention targeting older adults with diabetes.The primary aim of the study is to evaluate the effects of CCT on cognitive and…
- Trial name
- NCT02709629
- Testing
- Individualized and adaptive computerized cognitive training, Active control
- Where
- Israel
- Volunteers
- 85 people
- Sponsor
- Sheba Medical Center
Nasopharyngeal Carcinoma, De-escalation Therapy
Under Whole-course of Immunotherapy, Gradient Fractionated RT with CCT Versus CFRT with CCT for LANPC Who Achieved PR Post Induction Chemotherapy.
This prospective trial aims to enroll patients with stage III-IVA (AJCC 8th,) locoregionally advanced nasopharyngeal carcinoma (LANPC).
- Trial name
- NCT06675214
- Testing
- Full course of PD-1/PD-L1 blockades, Cisplatin-based induction chemotherapy, Standard-dose IMRT
- Where
- China
- Volunteers
- 586 people
- Sponsor
- Sun Yat-sen University
Primary Aldosteronism
Study on the Application of Liquid Chromatography-Tandem Mass Spectrometry for the Determination of Aldosterone and Renin Activity in the Diagnosis of Primary Aldosteronism by Captopril Test
Primary aldosteronism (PA) is the most common cause of secondary hypertension. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is more accurate than the traditional radioimmunoassay method in measuring aldosterone.
- Trial name
- NCT07691801
- Testing
- Captopril inhibition test(CCT)
- Where
- China
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Heroin Dependence
Economic Evaluation Comparing CCT With MMT in Hai Phong City, Vietnam
The study compared the effectiveness and cost-effectiveness of two dominant heroin dependence treatment approaches: center-based compulsory rehabilitation (CCT) and community-based voluntary methadone treatment (MMT) in Hai Phong…
- Trial name
- NCT03071315
- Testing
- CCT, MMT
- Where
- Vietnam
- Volunteers
- 522 people
- Sponsor
- The University of New South Wales
Stress, Depression
Evaluation of the Efficacy and Mechanisms of Change of Compassion Cultivation Training in Medical Students
The aim of this randomized, waitlist controlled trial is to examine the efficacy of the Compassion Cultivation Training (CCT©) in reducing psychological distress (i.e., stress, anxiety and depression) and burnout symptoms while…
- Conditions
- Stress, Depression, Anxiety, Burn Out
- Trial name
- NCT04690452
- Testing
- Compassion Cultivation Training
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid