Clinical trials: Burn Shock
Trauma, Burns
Inflammation and the Host Response to Injury (Burns)
The purpose of this study is to help improve our understanding of the biology involved in the body's response to serious trauma or burn injury.
- Conditions
- Trauma, Burns, Multiple Organ Failure
- Trial name
- NCT00257244
- Where
- 4 sites in United States
- Volunteers
- 280 people
- Sponsor
- Massachusetts General Hospital
Burns, Growth Factors, Combined Defect of
Keratinocyte Growth Factor and Cytokines in Burns.
KERATINOCYTE GROWTH FACTOR AND CYTOKINES IN SKIN BURNS. INTRODUCTION: Intense inflammatory responses are activated by burns that affect a large total body surface area.
- Conditions
- Burns, Growth Factors, Combined Defect of, Inflammation, Cytokine Storm
- Trial name
- NCT01302223
- Where
- Brazil
- Volunteers
- 8 people
- Sponsor
- Federal University of São Paulo
Post Burn Cubital Tunnel Syndrome
Post Burn Cubital Tunnel Syndrome Electrophysioligical and Functional Responses to High Intensity Laser Therapy Versus Extracorperal Shock Wave Therapy.
Post-burn cubital tunnel syndrome is a disabling complication that may occur after upper-limb burns involving the elbow due to edema, scar formation, and tissue compression around the ulnar nerve.
- Trial name
- NCT07102992
- Testing
- High intensity laser therapy, Shock Wave therapy, Ulnar nerve gliding exercises.
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ahram Canadian University
Burn Body Region Unspecified, Burn Shock
Enteral Resuscitation Nepal
Nepal and the South Asian sub-continent carry some of the highest rates of burn injury globally, with associated high morbidity and mortality.
- Trial name
- NCT05559489
- Testing
- Oral Rehydration Solution, Lactated Ringer
- Where
- Nepal
- Volunteers
- 240 people
- Sponsor
- Nepal Health Research Council
Trauma, Burns
Inflammation and the Host Response to Injury (Trauma)
The purpose of this study is to help improve our understanding of the biology involved in the body's response to serious trauma or burn injury.
- Conditions
- Trauma, Burns, Multiple Organ Failure
- Trial name
- NCT00257231
- Where
- 4 sites in United States
- Volunteers
- 610 people
- Sponsor
- Massachusetts General Hospital
Hand-burned Children
Comparative Study Between Botulinum Toxin-A Injection and Shock Waves on Hypertrophic Scars in Hand-burned Children
PURPOSE: The study aims to compare study between Botulinum toxin-A injection and shock waves therapy on hypertrophic scars in hand-burned children.
- Trial name
- NCT06174155
- Testing
- physical therapy treatment, Botulinum toxin-A injection in addition to physical therapy program, shock wave therapy in addition to physical therapy program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Burn Scar
The Clinical Utility of Extracorporeal Shock Wave Therapy on Burns
In burn patients, the wound healing process may lead to a fibrotic hypertrophic scar, which is raised, inflexible and responsible functional impairments.
- Trial name
- NCT04340271
- Testing
- Extracorporeal shock wave therapy, conventional occupational therapy
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Hangang Sacred Heart Hospital
Burns, Multiple Organ Failure
Early Haemadsorption in Major Burns
Major deep burns (>20% body surface, involving deep skin layers) and associated severe inflammatory reaction and their complication are one of the biggest challenge of intensive care.
- Conditions
- Burns, Multiple Organ Failure, Shock, Organ Dysfunction Syndrome, Multiple
- Trial name
- NCT04195126
- Testing
- CytoSorb haemadsorption device
- Where
- Hungary
- Volunteers
- 20 people
- Sponsor
- University of Pecs
Hypertrophy; Scar
Effect of Extracorporeal Shock Waves on Hypertrophy Scar
Assess the effect of extracorporeal shock waves on hypertrophy scar
- Trial name
- NCT03134053
- Testing
- extracorporeal shock-wave, massage
- Where
- Taiwan
- Volunteers
- 22 people
- Sponsor
- Mackay Memorial Hospital
Sepsis, Burn Injury
TDAP in Burn Patients (Group 2)
This study is following adult patients with serious burn injuries to better understand how their bodies respond to treatment and recovery.
- Conditions
- Sepsis, Burn Injury, Wound Healing, Critical Illness
- Trial name
- NCT07223684
- Testing
- Observational Cohort (No Intervention)
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Cicatrix, Hypertrophic
The Effect of Extracorporeal Shock Wave Therapy in the Treatment of Post Burn Scars
A prospective, randomized, controlled study. The patients were divided into two groups with twenty patients per group. The control group received the standard treatment for postburn scars.
- Trial name
- NCT04558944
- Testing
- Extracorporal Shock Wave Therapy
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Septic Shock, Acute Respiratory Distress Syndrome
CytOSorb TreatMent Of Critically Ill PatientS Registry
Registry intended to provide a data repository and reporting infrastructure for the surveillance of CytoSorb device use in real-world critical care settings, and to serve as an objective, comprehensive, and scientifically-based…
- Conditions
- Septic Shock, Acute Respiratory Distress Syndrome, Trauma, Rhabdomyolysis
- Trial name
- COSMOS (NCT05146336)
- Testing
- CytoSorb
- Where
- 28 sites in Austria, Germany and 4 more
- Volunteers
- 3,000 people
- Sponsor
- CytoSorbents, Inc
Shortness of Breath, Chest Pain
Checklists Resuscitation Emergency Department
The study will systematically evaluate how an emergency manual-a collection of checklists and fact sheets-affects the performance of resuscitation teams during the management of priority one patients in an emergency department.
- Conditions
- Shortness of Breath, Chest Pain, Abdominal Pain, Altered Mental Status
- Trial name
- NCT05649891
- Testing
- Emergency Manual
- Volunteers
- 2,000 people
- Sponsor
- Region Skane
Burns, Trauma
Microcirculatory Assessment in Patients With Trauma and Severe Burns
Predict the development of multiple organ failure in patients with trauma and severe burns.
- Trial name
- NCT01922960
- Testing
- micro-imaging
- Where
- United States
- Sponsor
- University of South Alabama
Septic Shock, Severe Trauma
REAnimation Low Immune Status Markers
The fact that sepsis disrupts immune system homeostasis by inducing an initial cytokine storm, that participates to occurrence of organ failures and early death, followed by a compensatory anti-inflammatory response leading to…
- Conditions
- Septic Shock, Severe Trauma, Severe Burn, Major Surgery
- Trial name
- REALISM (NCT02638779)
- Testing
- Blood sampling
- Where
- France
- Volunteers
- 552 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Burns Shock
Study on Efficacy and Safety of Human Albumin in Burn Shock Recovery
To explore the effects and safety of human albumin in burn shock recovery, and then provide a theoretical basis for its rational use.
- Trial name
- NCT04928859
- Testing
- Albumin
- Volunteers
- 364 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Burn Scar, Burns
Shock Wave Therapy Versus Conventional Physical Therapy for Partial- Thickness Forearm Burn Scars
Burn injuries can lead to significant physical and psychological challenges, particularly when they result in scarring. Burn scars can lead to a variety of complications that significantly impact a patient's quality of life1.
- Trial name
- NCT07234305
- Testing
- Shock wave, Traditional Physical Therapy
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- MTI University
Burns, Ascorbic Acid Deficiency
Low Dose Vitamin C in Burns >20% Compared to Previous Studies With High Dose Vitamin C
Burn injury is marked by a large release of inflammatory mediators which disrupt the normal capillary barrier and cause a rapid shift of intravascular fluid into interstitial spaces, ultimately leading to shock and death.
- Conditions
- Burns, Ascorbic Acid Deficiency, Burn Shock, Burn Degree Second
- Trial name
- NCT05612867
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Arrowhead Regional Medical Center
Burns, Shock
The Acute Burn Resuscitation Multicenter Prospective Observational Trial
This is a prospective, non-interventional, observational study of consecutive burn patients admitted to 20 selected burn centers in North America.
- Trial name
- ABRUPT (NCT03144427)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- American Burn Association
Inflammatory Response, Multi Organ Failure
Association of Cytokines With the Development of Complications in Burn and Toxic Epidermal Necrolysis (TENS) Patients
This study will involve blood draws to test for specific cytokines. The study goal is to gain a better understanding of the role of inflammatory response in the development of specific complications in burn and TENS patients.
- Conditions
- Inflammatory Response, Multi Organ Failure, Nosocomial Infection, Deep Vein Thrombosis
- Trial name
- NCT04252651
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Joseph M. Still Research Foundation, Inc.