Clinical trials: Burn Degree Second
Partial-Thickness Burn, Thermal Burn
Silver Sulfadiazine With Hyaluronic Acid Versus Silver Sulfadiazine Alone in Partial-Thickness Burns
Partial-thickness burns are commonly treated with topical silver sulfadiazine; however, its use may delay epithelialization due to cytotoxic effects on regenerating cells.
- Trial name
- NCT07367087
- Testing
- Silver Sulfadiazine With Hyaluronic Acid, Silver Sulfadiazine
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Dr Muhammad Naveed Shahzad
Burns
Evaluation of Antimicrobial Soft Silicone, Silver Containing, Foam Dressing, Mepilex Border Ag, in Second Degree Burns
The investigation is designed as an open, non-controlled, post-marketing investigation. Subjects with at least one second degree burn less than 9.5x15 cm in size at 1-3 sites will be included.
- Trial name
- NCT01418482
- Testing
- Mepilex Border Ag
- Where
- 2 sites in Sweden
- Volunteers
- 15 people
- Sponsor
- Molnlycke Health Care AB
Skin Burn Degree Second
Compare the Efficacy of Mepilex and Keramatrix in Second Degree Burn Wounds
The purpose of this study is to determine the extent to which Keramatrix dressing promotes the healing of second-degree burn wounds in pediatric patients.
- Trial name
- NCT01790763
- Testing
- Keramatrix, Mepilex
- Where
- United States
- Sponsor
- The University of Texas Medical Branch, Galveston
Wounds and Injuries
Acute Partial Thickness Burn Study Comparing Transforming Powder Dressing to Standard of Care Dressing
This study is being performed to assess the effectiveness of Altrazeal(R) Transforming Powder Dressing (TPD) in patients with partial thickness burns compared to the current standard of care (SOC) dressing.
- Trial name
- NCT05424354
- Testing
- Altrazeal (R) Transforming Powder Dressing, Standard of Care burn dressing
- Where
- 6 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ULURU Inc.
Acute Deep Partial Thickness Thermal Burns
Applying Platelet Rich Plasma (PRP) Gel to Acute Deep Partial Thickness Thermal Injuries
The study will examine the safety of using a concentration of proteins from a patient's own blood, referred to as platelet rich plasma or (PRP) and applying it to a second degree burn wound.
- Trial name
- NCT02169362
- Testing
- Autologous Platelet Rich Plasma (PRP) Gel (Magellan® Bio-Bandage™)
- Where
- 8 sites in United States
- Volunteers
- 36 people
- Sponsor
- Arteriocyte, Inc.
Burns
Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns
To compare MW-III to Silvadene® Cream 1% (Silver Sulfadiazine) with respect to "time to healing" (≥95% re-epithelialization) of a partial thickness target thermal burn.
- Trial name
- NCT01297400
- Testing
- Investigational Drug, MW-III, Silvadene® Cream 1% [Silver Sulfadiazine]
- Where
- 6 sites in United States, Mexico
- Volunteers
- 60 people
- Sponsor
- Skingenix, Inc.
Burn
A Study to Evaluate the Safety of ALLO-ASC-DFU in the Subjects With Deep Second-degree Burn Wound
This is a phase I study to evaluate the safety of ALLO-ASC-DFU for the treatment of deep second-degree burn wound patients. ALLO-ASC-DFU is a hydrogel sheet containing allogenic adipose-derived mesenchymal stem cells.
- Trial name
- NCT02394873
- Testing
- ALLO-ASC-DFU
- Where
- South Korea
- Volunteers
- 5 people
- Sponsor
- Anterogen Co., Ltd.
Burn, Second Degree Burns
Effect of Laughie on Pain Anxiety and Pain Level in Second-Degree Burn Patients
Burn injuries are traumatic conditions that seriously affect individuals' quality of life, both physically and psychologically. Second-degree burns, in particular, affect the superficial and/or deep layers of the dermis, causing…
- Trial name
- LA-PAP (NCT07386821)
- Testing
- Laughie
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Hacettepe University
Skin Burn Degree Second
Stem Cell Therapy to Improve Burn Wound Healing
This study will determine the safety of allogeneic stem cell therapy from healthy donors, for 2nd degree burn wounds of less than 20% Total Body Surface Area (TBSA), at four different dose levels.
- Trial name
- NCT02104713
- Testing
- Allogeneic (MSC's) Application to the Burn Wounds
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- E.Badiavas
Burns
Oleogel-S10 Versus Standard of Care in Healing of Grade 2a Burn Wounds
The main goal of this phase III clinical trial is to show safety and efficacy of Oleogel-S10 in the acceleration of wound healing of grade 2a burn wounds.
- Trial name
- NCT01657292
- Testing
- Oleogel-S10 ointment, Octenilin® wound gel
- Where
- 9 sites in Germany, Sweden and 2 more
- Volunteers
- 61 people
- Sponsor
- Birken AG
Second Degree Burns
Comparison of Amniotic Membrane Dressing and Aquacel®Ag in Second-degree Burns
To compare the outcome of amniotic membrane dressing versus Aquacel® Ag dressing with respect to the duration of healing in patients with second-degree burns within the local demographic setting.
- Trial name
- NCT07300137
- Testing
- preserved amniotic membrane dressing
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Patel Hospital, Pakistan
Burns Second Degree
Thermal Imaging and Pediatric Burns
The need to cover a burn with a skin graft is determined primarily by its depth. In fact only burns of the second deep degree or the third degree are likely to be grafted.
- Trial name
- FLIRPED (NCT03702972)
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Deep Partial Thickness Burn
Efficacy and Safety Study of rhGM-CSF Gel to Treat Deep 2nd Thickness Burn
This was a multicenter, randomized, phase Ⅳ study, to investigate the extensive efficacy and safety of Recombinant Human Granulocyte/Macrophage Colony-stimulating Factor Hydro-gel for Topical Application (rhGM-CSF Gel) on deep…
- Trial name
- rhGM-CSF (NCT01785784)
- Testing
- rhGM-CSF Gel
- Volunteers
- 2,510 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Third Degree Burn, Second Degree Burn
Diagnostic of Infections Following Major Abdominal Surgery and Burn Injury
This study was designed to investigate, if new biomarkers may improve the early diagnostic of infections following major abdominal surgery and severe burn injuries.
- Trial name
- Earlygnost (NCT01055587)
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Klinikum St. Georg gGmbH
Burn Wound, Pressure Ulcers Stage II
Study to Evaluate the Performance and Safety of the Medical Device Argogen
A wound, i.e., a break in the skin, can result from several reasons. Pressure ulcers (also called pressure sores, bed sores and decubitus ulcers) are localized damage to the skin and underlying soft tissue usually over a bony…
- Conditions
- Burn Wound, Pressure Ulcers Stage II, Pressure Ulcers Stage III
- Trial name
- NCT05649332
- Testing
- Argogen (silver zeolite powder)
- Where
- 2 sites in Romania
- Volunteers
- 58 people
- Sponsor
- Signorini Medicale S.r.l.
Burns Degree Second
Evaluation of a Management Strategy for Second-degree Fibrinous Burns Integrating a Poly-absorbent Dressing
The management of the local treatment of second-degree burns has an influence on the healing time and thus on the quality of the healing process.
- Trial name
- HYDRA-B (NCT05347654)
- Testing
- Local treatment with silver sulphadiazine only, Local treatment with silver sulphadiazine followed by URGOCLEAN® dressing
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Hospices Civils de Lyon
Burn, Burn Wounds - Partial Thickness (2nd Degree)
Phase II Clinical Trial of KJ101in the Treatment of Deep II Degree Burns
This multicentre, randomised, double-blind, dose-finding, active- and placebo-controlled Phase II clinical trial will evaluate the safety, efficacy, pharmacokinetic profile, and immunogenicity of KJ101 for the debridement of deep…
- Trial name
- NCT07025408
- Testing
- KJ101, Chymotrypsin
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Shanghai Bao Pharmaceuticals Co., Ltd.
Partial-thickness Burn Wounds
Evaluating Whether Intact Fish Skin Graft Can Decrease the Need for Autograft in the Treatment of Deep Partial-Thickness Burns
The goal of this randomized controlled clinical trial is to determine whether use of Kericis Intact Fish Skin Graft (IFSG) can decrease the amount of autograft tissue needed for treatment of deep partial-thickness burns in…
- Trial name
- LOGI (NCT07326657)
- Testing
- Intact fish skin graft, autograft
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Kerecis Ltd.
Thermal Injury, Deep Partial-Thickness Burn
Safety and Efficacy Study of Autologous Engineered Skin Substitute to Treat Partial- and Full-Thickness Burn Wounds
The purpose of this research study is to test how well the investigational treatment, Engineered Skin Substitutes (ESS-W), works for covering and treating burn wounds.
- Conditions
- Thermal Injury, Deep Partial-Thickness Burn, Full-Thickness Burn
- Trial name
- NCT01655407
- Testing
- Autologous Engineered Skin Substitute, Split-Thickness Autograft (AG)
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- Amarantus BioScience Holdings, Inc.
Burn, Burn Contracture of Skin
Development and Clinical Study of Burn Wound Nursing Dressing Based on Sodium Hyaluronate Carbomer Composite Hydrogel
Development and clinical study of burn wound nursing dressing based on sodium hyaluronate carbomer composite hydrogel
- Conditions
- Burn, Burn Contracture of Skin, Burn Degree Second
- Trial name
- NCT07568600
- Testing
- sodium hyaluronate carbomer composite hydrogel
- Volunteers
- 30 people
- Sponsor
- The First Affiliated Hospital of Xinxiang Medical College