Clinical trials: Burn
Blood Sugar; High, Overweight and Obesity
Effect of a Glucagon Like Peptide 1 (GLP1) Booster in Healthy Humans
BACKGROUND GLP1 booster (GB) was designed to stimulate the endogenous production of GLP1, which in turn releases insulin, controls blood glucose level, suppresses appetite and thus helps people lose weight.
- Conditions
- Blood Sugar; High, Overweight and Obesity, Fat Burn, Obesity
- Trial name
- NCT06333496
- Testing
- GLP-1 Booster (GB)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Alpine Biotech LLC
Intubation; Difficult or Failed
Application of THRIVE in Burn Children With Suspected Difficult Airway
In order to improve intubation conditions in burn children, our aim is to investigate the efficacy of transnasal humidified rapid-insufflation ventilatory exchange technique（THRIVE) in children aged between 0 and 18 years who…
- Trial name
- NCT06459076
- Testing
- Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE)
- Volunteers
- 120 people
- Sponsor
- Shuxiu Wang
UVB Phototherapy Burn, Insulin-like Growth Factor 1
Gene Expression Changes In Young and Geriatric Skin
This study does not involve any particular diagnosis. The goal of this research study is to explore the effects of artificial sunlight (ultraviolet B radiation; UVB) on the skin of young adults versus geriatric adults.
- Conditions
- UVB Phototherapy Burn, Insulin-like Growth Factor 1, Aging
- Trial name
- NCT03932162
- Testing
- Insulin-Like Growth Factor 1, No Insulin-Lie Growth Factor 1
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Wright State University
Burns Shock
Study on Efficacy and Safety of Human Albumin in Burn Shock Recovery
To explore the effects and safety of human albumin in burn shock recovery, and then provide a theoretical basis for its rational use.
- Trial name
- NCT04928859
- Testing
- Albumin
- Volunteers
- 364 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Burn Injury
Vitamin E Supplementation in Burn Patients
Burned patients because of their increased oxidative stress have severely depleted vitamin E, which is a dietary antioxidant. Oxidative stress is responsible for much of the pathophysiology seen in burned patients, which leads to…
- Trial name
- NCT01413620
- Testing
- dl-alpha-tocopheryl acetate
- Where
- United States
- Sponsor
- Shriners Hospitals for Children
Burns
Intraoperative Small-dose Esketamine Infusion for Pain Control in Burn Patients
This study aim to determine whether a small-dose esketamine infusion can be used for pain control in severe burn patients, and thereby reduce the total intra-operative opioid requirement.
- Trial name
- NCT04682782
- Testing
- Esketamine, Saline
- Where
- China
- Volunteers
- 26 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Burns, Sepsis
The Impact of Continuous Renal Replacement Therapy on the Outcomes of Burn Patients With Early Phase of Sepsis
The purpose of this study is to determine if early application of CRRT will result in an improvement of clinical outcomes of burn patients during the early phase of sepsis
- Trial name
- CRRT (NCT01501097)
- Testing
- Continuous Renal Replacement Therapy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Southwest Hospital, China
Hand Burns, Flexion Contracture
Comparison of Outcome of Post Burn Flexion Contracture Release Under Tourniquet Verses Tumescent Technique in Children
Post burn flexion contractures are common in pediatric age group. Release of contracture and coverage with full thickness skin graft (FTSG) is a widely used procedure for this problem.
- Trial name
- NCT02501720
- Testing
- post burn flexion contractures release under tourniquet control, post burn flexion contractures release using tumescent solution, Contracture release and application of FTSG
- Volunteers
- 80 people
- Sponsor
- King Edward Medical University
Virtual Reality, High Fidelity Simulation Training
Preliminary Exploration of Applying Multi-person Simulation Training to Improve Nurse-led Burn and Scald Nursing Care
The purpose of this study was to compare the learning performance of trainees before and after learning burns and scald nursing care by applying the burns and scald virtual reality (VR) training module multi-person interactive…
- Trial name
- NCT05493774
- Testing
- Multi-person virtual reality simulation scenario training, Multi-person high-fidelity simulation scenario training
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chimei Medical Center
Inhalation Injury, Pulmonary Function
Effects of IMT on Pulmonary Functions IN CASES With Inhalation Injury
The current study aimed to investigate the effect of inspiratory muscle training (IMT) on pulmonary functions (FEV1and FVC), and respiratory muscle strength in patients with inhalation injury, which may prove to be a promising…
- Conditions
- Inhalation Injury, Pulmonary Function, Respiratory Muscle Strength
- Trial name
- NCT05190497
- Testing
- Exercise group
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Burn Injury, Acute Wound
Cutaneous Microcirculation After Plasma Therapy
In plastic and reconstructive surgery, treatment strategies of second-degree burns, superficial wounds, burn scars, flaps and chronic wounds aim at reducing infection and improving microcirculation.
- Conditions
- Burn Injury, Acute Wound, Chronic Wound, Burn Scar
- Trial name
- NCT02417818
- Testing
- Plasma Therapy (PlasmaDerm), Repetitive Plasma Therapy (repetitive PlasmaDerm)
- Where
- Germany
- Volunteers
- 240 people
- Sponsor
- University Hospital Schleswig-Holstein
Burn Wound
Safety Study of a Novel Wearable Phototherapy System for the Management of Acute Burn Wounds
The primary purpose of this first-in-human, early feasibility study is to assess safety and feasibility of the Low-Irradiance Monochromatic Biostimulation (LIMB) System as a phototherapeutic intervention for the management of…
- Trial name
- NCT03948360
- Testing
- Low-Irradiance Monochromatic Biostimulation (LIMB) Device, Standard of Care
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Rogers Sciences Inc.
Scars
Burn Scar Appearance After Treatment With Fractional Carbon Dioxide (CO2) Laser
The purpose of this study is to determine if fractional carbon dioxide laser treatment of a burn scar is a more effective method for improving the appearance of scars than the current available treatments.
- Trial name
- NCT00969215
- Testing
- Lumenis fractional carbon dioxide laser
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Moy-Fincher Medical Group
Burns, Muscle Weakness
Reallocating Rehabilitation Time to Wii Fit or Pilates After Lower-Limb Burn Injury
This randomized controlled trial will evaluate whether reallocating part of a fixed-duration supervised rehabilitation session to Wii Fit or Pilates will improve functional outcomes in adults with healed lower-extremity burns.
- Conditions
- Burns, Muscle Weakness, Exercises, Functional Performance
- Trial name
- NCT06081504
- Testing
- Wii fit exercises program, Pilates exercises program, Standard physical therapy program
- Where
- 2 sites in Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Pain
Lidocaine For Treatment of Post-operative Pain From Donor Sites Following Burn Injury.
Burn pain is known to be one the most severe forms of acute pain often requiring large amounts of narcotics in addition to other adjuvants.
- Trial name
- LidocaineBurn (NCT02229578)
- Testing
- Lidocaine
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Florida
Burns
Gaming Based PNF on Spatiotemporal Parameters in Upper Limb Burned Patients
Burn injuries are among the most severe forms of trauma, often leading to significant physical and psychological challenges. The rehabilitation process for burn patients, particularly those with upper limb injuries, is complex…
- Trial name
- NCT07183943
- Testing
- Proprioceptive neuromuscular facilitation (PNF), Visual reality (VR), PNF and VR
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- MTI University
Burn Wounds
SWC for Treatment of Superficial Partial-Thickness Burns
The purpose of this study is to test the safety and effectiveness of SynePure™ Wound Cleanser when used in combination with Catasyn™ Advanced Technology Hydrogel for the treatment of superficial partial-thickness burn wounds.
- Trial name
- NCT05877638
- Testing
- SynePure Wound Cleanser and Catasyn Advanced Technology Hydrogel, SILVADENE Cream 1% (silver sulfadiazine)
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Synedgen, Inc.
Sepsis - to Reduce Mortality in the Intensive Care Unit, Burns Involving 20% or More of Body Surface
Evaluating the Accuracy of Multiple Blood Tests to Diagnose Sepsis in Adult Burn Patients
This prospective diagnostic accuracy study evaluates the performance of presepsin and C-reactive protein (CRP) as early biomarkers for suspected sepsis in adult burn patients.
- Trial name
- BioBurnSepsis (NCT07126574)
- Where
- South Korea
- Volunteers
- 165 people
- Sponsor
- Dohern Kym
Burn
Determining Elements of Anti-Fungal Immunity in BURN Patients
Scientific justification Invasive fungal diseases (IFDs) pose a substantial threat, especially in immunocompromised patients, necessitating urgent research focus and therapeutic advancements.
- Trial name
- DEFI-BURN (NCT06828458)
- Testing
- Biological sampling
- Where
- France
- Volunteers
- 327 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Burn
Microbiota in Children With Severe Burn Injury
The research protocol consists of taking aliquots of biological specimens from skin swabs, nasopharyngeal swabs, and fecal swabs.
- Trial name
- MIBUS (NCT07098377)
- Testing
- nasopharyngeal swab for biological sample analysis
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS