Clinical trials: Brown Adipose Tissue
Breast Cancer
The Effects of HER2 Receptor Signaling on Human Brown Fat Activity
The objective of this observational study is to investigate the significance of the HER2 receptor for brown fat activity in humans.
- Trial name
- HEAT (NCT06222957)
- Testing
- None (Observational study)
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Obese
Monounsaturated Fatty Acids and Brown/Beige Adipose Tissue in Humans
Considering the high prevalence of obesity its comorbidities in Brazil and in the world, different therapeutic measures have been suggested.
- Trial name
- NCT03024359
- Testing
- Extra virgin olive oil
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Polycystic Ovary Syndrome (PCOS)
Brown Adipose Tissue Modulation in Polycystic Ovary Syndrome Using Infrared Thermography
This study will investigate brown adipose tissue-related physiological responses in women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT07896642
- Testing
- inositol
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Health and Technology University
Mitochondrial Metabolism Disorders, Adipose Tissue, Brown
Human Brown Adipose Tissue and Mitochondrial Respiration
This study is focused on measuring mitochondrial activity of human brown adipose tissue. During surgery, adipose tissue biopsies from white and brown adipose tissue will be collected from the deep neck area.
- Conditions
- Mitochondrial Metabolism Disorders, Adipose Tissue, Brown, Aging, Obesity
- Trial name
- NCT03111719
- Where
- Netherlands
- Volunteers
- 180 people
- Sponsor
- Maastricht University Medical Center
Adipose Tissue, Brown, Insulin Resistance
Effect of Fluvastatin on Brown Fat Activity
The purpose of this study is to elucidate the effects of Fluvastatin on brown adipose tissue activity in humans.
- Conditions
- Adipose Tissue, Brown, Insulin Resistance, Clinical Trial
- Trial name
- FluvaBAT (NCT03189511)
- Testing
- Fluvastatin
- Where
- 2 sites in Switzerland
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Type 2 Diabetes
Pharmacological Activation of Brown Adipose Tissue Metabolism
Lean tissue intracellular triglycerides (ICTG) accretion is an important marker of lean tissue lipotoxicity that significantly contributes to the development of type 2 diabetes (T2D).
- Trial name
- GB6 (NCT02811289)
- Testing
- Mirbetriq (Mirabegron), cold exposure, injection of 18FDG
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Obesity, Atherosclerosis
Observational Study of Early Metabolic and Vascular Changes in Obesity
To work against the increasing burden of obesity, the STYJOBS / EDECTA (STYrian Juvenile OBesity Study / Early DetECtion of Atherosclerosis) project was started at the Medical University of Graz in 2003.
- Conditions
- Obesity, Atherosclerosis, Inflammation, Adiponectin Deficiency
- Trial name
- STYJOBS (NCT00482924)
- Testing
- Lifestyle intervention
- Where
- Austria
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Adiposity, Metabolic Complication
Insight Into New Brown Adipose Tissue Activators.
The general purpose of the study was to provide new information about the role of macronutrients intake, metabolomics, proteomics and microRNA on BAT activation.
- Conditions
- Adiposity, Metabolic Complication, Metabolic Disturbance, Healthy
- Trial name
- NCT04787952
- Testing
- cold expossure
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok