Clinical trials: Bronchitis
Bronchiolitis
Nebulised 3% Hypertonic Saline Versus 0.9% Saline for Treating Patients Hospitalized With Acute Bronchiolitis
Bronchiolitis is an acute viral infection of the lower respiratory tract. It is most commonly caused by respiratory syncytial virus (RSV).
- Trial name
- NCT06069336
- Testing
- Hypertonic saline, Normal saline
- Where
- 3 sites in Poland
- Volunteers
- 180 people
- Sponsor
- Szpital im. Św. Jadwigi Śląskiej
Emphysema, Chronic Obstructive Pulmonary Disease
Emphysema Research Registry and Biosample Repository
The Comprehensive Lung Center (CLC) at the University of Pittsburgh Medical Center (UPMC Health System) provides patients with any type of breathing or lung disorder a full range of diagnostic and therapeutic services.
- Conditions
- Emphysema, Chronic Obstructive Pulmonary Disease, Chronic Bronchitis
- Trial name
- NCT00307281
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Chronic Bronchitis
VX-770 for the Treatment of Chronic Bronchitis
This research study will test how well a new drug affects bronchiectasis or chronic bronchitis. The new drug, Ivacaftor (KALYDECO), is a drug that has recently been approved by the U.S.
- Trial name
- NCT03251911
- Testing
- Ivacaftor (VX-770)
- Where
- United States
- Sponsor
- University of Alabama at Birmingham
Cough
An Investigation Into the Mechanism of Inhalation Cough Challenge
Despite its commonplace use in respiratory medicine the mechanism whereby inhalation challenge with a variety of mild acid aerosols produces a dose related and predictable cough is unknown.
- Trial name
- NCT02039999
- Testing
- Nebulised citric acid in serial dilutions, Nebulised ATP solution in serial dilutions, Nebulised TRPA1 agonist solution in serial dilutions
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Acute Bronchitis
Evaluate the Efficacy and Safety of Acute Bronchitis Symptoms Improvement for Bronpass Tab. Compared to Erdos Capsule
The purpose of this clinical trial is to evaluate the acute bronchitis symptom relief effect of Bronpass tab. compared to Erdos capsule, and compare and evaluate the safety.
- Trial name
- NCT06038084
- Testing
- Bronpass Tab., Erdos capsule
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Kwang-Ha Yoo
Bronchiolitis
Suctioning of NOse Therapy in Bronchiolitis
Research Questions: Primary: In otherwise healthy infants 4 weeks to 12 months of age discharged home from the ED with acute bronchiolitis,1 is there a difference in the probability of "treatment failure" by 72 hours post…
- Trial name
- SNOT (NCT03361371)
- Testing
- Battery operated nasal aspirator, Suction bulb
- Where
- 3 sites in Canada
- Volunteers
- 373 people
- Sponsor
- The Hospital for Sick Children
Neck Pain, Chronic Neck Pain
Prediction of Recovery in Patients With Neck Pain
This prognostic prediction model will be a reference for the health care professionals in clinical decision making and subsequent outcomes in dealing with patients having sub-acute and chronic neck pain, as well as, it will be a…
- Conditions
- Neck Pain, Chronic Neck Pain, Cervical Radiculopathy
- Trial name
- NCT04924764
- Testing
- Conventional physical therapy.
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- Riphah International University
COPD, Chronic Obstructive Pulmonary Disease
Melodica Orchestra for Dyspnea: Safety and Feasibility Pilot
This project seeks to pilot-test the feasibility of using a melodica training program to teach pursed lip breathing for Veterans with chronic obstructive pulmonary disease (COPD) with moderate to severe dyspnea (shortness of…
- Conditions
- COPD, Chronic Obstructive Pulmonary Disease, Dyspnea, Breathlessness
- Trial name
- MELODY (NCT03653104)
- Testing
- Melodica Intervention, Pulmonary Health Education
- Where
- United States
- Sponsor
- VA Quality Enhancement Research Intiative
Leukemia, Myelogenous
TKI Discontinuation in CML Patients of China
The primary objective of this study is to describe the maintenance of the molecular remission after tyrosine kinase inhibitor (TKI) disconnection in chronic myeloid leukaemia (CML) patients in China in the real-world clinical…
- Conditions
- Leukemia, Myelogenous, Chronic, BCR-ABL (Breakpoint Cluster Region-abelson Murine Leukemia)
- Trial name
- TFR_china (NCT03251352)
- Where
- China
- Volunteers
- 98 people
- Sponsor
- Shenzhen Second People's Hospital
Diabetes, Chronic Kidney Diseases
Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY)
This research programme seeks to combine the resources of NHS primary care, with the leading spectroscopic work in low-magnetic fields of the Wilson Group (Nottingham Trent University) to demonstrate the potential for benchtop…
- Conditions
- Diabetes, Chronic Kidney Diseases, Cancer, Bowel Disease
- Trial name
- BRANCH-P (NCT05473325)
- Where
- United Kingdom
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Willows Health
Cholecystitis, Acute, Cholecystitis, Chronic
BDD With UDCA Therapy After Laparoscopic Cholecystectomy
Prospective Study for the Effects of Biphenyl Dimethyl Dicarboxylate and Ursodeoxycolic Acid Therapy on Liver Function and Quality of Life After Laparoscopic Cholecystectomy Primary endpoint: peak level of postoperative AST…
- Trial name
- BULQ-LC (NCT03578055)
- Testing
- BDD with UDCA
- Where
- South Korea
- Volunteers
- 172 people
- Sponsor
- Ewha Womans University Mokdong Hospital
Severe Bronchiolitis
Prone Position Effects on Work of Breathing and Intrinsic PEEP in Children With Severe Acute Viral Bronchiolitis
Acute viral bronchiolitis is the first cause of respiratory distress in infant. Airway inflammation increases the respiratory system resistances and dynamic hyperinflation. This leads to an increase in the work of breathing.
- Trial name
- BRONCHIO-DV (NCT02602678)
- Testing
- Supine then Prone position, Prone then supine position
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Hospices Civils de Lyon
COPD
The Effect of QVAR on Lung Functioning in Chronic Obstructive Pulmonary Disease
This is an investigator-sponsored research study to evaluate if treatment with HFA-134a beclomethasone (QVAR) has an effect on peripheral (or outer) airway inflammation and airway "remodeling" or scarring in subjects with COPD.
- Trial name
- NCT00238082
- Testing
- HFA-134A Beclomethasone DIpropionate (QVAR)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Jewish Health
Chronic Hypersecretions
Efficacy of Temporary Positive Expiratory Pressure (TPEP) in Chronic Hypersecretion
Mechanical devices to increase the individual's bronchial hygiene are commonly used in patients with chronic retention of secretions and abnormal cough reflex.
- Trial name
- UNIKO (NCT00700388)
- Testing
- TPEP device (UNIKO), MABT (Manually assisted breathing techniques)
- Where
- 6 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Villa Pineta Hospital
Bronchiolitis
Nebulized 5% Hypertonic Saline for the Treatment of Bronchiolitis
The investigators reasoned that a hypertonic saline concentration higher than 3% could be safe and more efficacious in the treatment of bronchiolitis, alleviating severe symptoms and preventing the need for hospitalization in…
- Trial name
- NCT01016249
- Testing
- Treatment 1. (5% Hypertonic saline + Epinephrine), Treatment 3. (3% Hypertonic saline + Epinephrine), Treatment 2. (Normal saline + Epinephrine)
- Where
- Qatar
- Volunteers
- 187 people
- Sponsor
- Hamad Medical Corporation
Spinal Cord Injuries, Cerebral Palsy
Mobile Health Self-Management and Support System for Chronic and Complex Health Conditions
This study will assess the benefits of using mobile health system designed for individuals with chronic and complex health conditions (such as those with Spinal Cord Injury,Cerebral Palsy, Spina Bifida, and Traumatic Brain…
- Conditions
- Spinal Cord Injuries, Cerebral Palsy, Spinal Dysraphism, Brain Injuries
- Trial name
- NCT02592291
- Testing
- MHealth
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Neck Pain
The Effects of Two Different Home-exercise Programmes on Women Suffering Long Term Neck/Shoulder Muscle Pain
The purpose of this study is to investigate the effects of specific neck/shoulder muscle exercises on pain, function, biochemistry and psychological factors in women suffering chronic neck/shoulder pain.
- Trial name
- NCT01876680
- Testing
- Stretching and aerobic exercise, Strength training
- Where
- Sweden
- Volunteers
- 57 people
- Sponsor
- Linkoeping University
Hepatitis C, Chronic; AUD
Hepatitis C Alcohol Reduction Treatment
Subjects are being asked to take part in a research study to test two levels of alcohol services for patients with hepatitis C virus (HCV) who drink alcohol.
- Trial name
- HepART-RCT (NCT02176980)
- Testing
- Brief alcohol counseling, Group and Individual Therapy Sessions
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- Duke University
Chronic Graft-versus-host-disease
Efficacy and Safety of SCM-CGH in Patients With Steroid-Refractory or Dependent Chronic Graft-Versus-Host Disease
The purpose of this study is to evaluate efficacy of SCM-CGH in participants with steroid dependent/refractory chronic graft versus host disease (cGVHD) by measuring overall cGVHD response (complete response [CR] and partial…
- Trial name
- NCT04189432
- Testing
- SCM-CGH
- Where
- 11 sites in South Korea
- Volunteers
- 84 people
- Sponsor
- SCM Lifescience Co., LTD.
Neck Pain, Cervical Pain
The Effect of Cervical Taping on Neck Pain and Kinematics in Patients With Chronic Neck Pain
Objective: This study examined the effects of elastic tape applied to the neck on patients experiencing chronic neck pain. Background: Neck pain is often persistent or recurrent.
- Conditions
- Neck Pain, Cervical Pain, Chronic Pain
- Trial name
- NCT02915887
- Testing
- Cervical Taping
- Where
- Israel
- Volunteers
- 27 people
- Sponsor
- University of Haifa
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